At the same time, the work of building mathematical model and optimizing the algorithm were completed. Results: Obtained the auto-fluorescence spectra and quantity of riboflavin in the corresponding tissue; the mean quantity of riboflavin in cancer and normal tissue are 609 ± 57 ng/g, 786±91 ng/g respectively.
Methods The LIAF spectra of normal lung and lung cancer in 42 surgical specimens were examined with a detecting system which consists of an YAG laser(wavelength 355 nm) and an optical multichannel analyzer(OMA), pathological examinations were done in every testing spots.
The multivariate statistical discrimination method of PCA and SMLR together can effectively distinguish normal tissues from early cancers and advanced cancers with high sensitivity and specificity by means of systemic 5-ALA at low dose. laser induced fluorescence 5-ALA-based technique is promising for the detection of colonic early cancer.
Guanidine-like compounds have been investigated since the first observations of their therapeutic potential some 30 years ago in fields of cancer and virology.
Epidermal Growth Factor Receptor (EGFR) is among the growth factor receptor kinases that have been implicated in as being important in cancer.
Inhibitive Effect of Prodigiosin on the Proliferation of Human Malignant Pancreatic Cancer Cells
Pancreatic cancer is not only common, but also extremely difficult to treat, for which it has been called "the challenge of the twenty-first century".
In this study, we find that prodigiosin could effectively inhibit the proliferation of human pancreatic cancer cells H8898 in a dose-and-time-dependent manner, with an IC50 of 75μmol according to the results of MTT and cell proliferation assays.
To determine the correlation of Sef with human diseases, Sef expression patterns were observed in cell lines and human cancer tissues.
Results demonstrated that Sef might be up-regulated in the cancer tissues suggesting a possible role of Sef in pathophysiology of human diseases.
LOH and MSI of the FHIT were detected by using PCR at 4 microsatellite loci: D3S 1300, D3S 4103, D3S 1481, D3S 1234 in cancer tissues from 50 patients with primary GC, with normal mucosa acting as matched controls.
Our results showed over expression of EMMPRIN in advanced stages of breast cancer tissues compared with benign tumor tissue samples.
The expression level of Pescadillo was increased significantly in breast cancer tissues compared with their paired margin tissues.