A Monte Carlo model was developed to simul at e laser energy transport in biological tissues photon-number-independently and mesh-independently for laser-induced interstitial thermotherapy (LITT). In ad dition, laser transport characters in human liver tissue and prostate tissue at 1064 nm and 850 nm as well as its main influential factors were analyzed based on the present model.
A physical and mathematical model considering the dynamic changes of tissue physical properties was developed in this paper to simulate the energy and temperature history during laser-induced interstitial thermotherapy (LITT). The energy transport of laser in tissue was simulated using the Monte Carlo method, and then the temperature distribution and the thermal damage volume were numerically calculated based on the Pennnes' Bioheat Equation and Arrhenius assumptions.
Considering the different physical properties between the tumor and the surrounding normal tissue, a two layer model was developed to describe the energy transport and the temperature behavior in the tumor tissue during the laser induced interstitial thermotherapy (LITT). Photon transport was simulated with the Monte Carlo method and then energy distribution was used to calculate the temperature distribution with Pennes bio heat equation. Both the time required to coagulate the tumor and the thermal damage depth are numerically predicted.
The numerical results showed that the dynamic changes of tissue physical properties significantly affected the thermal damage volume and should be carefully considered to properly predict the clinical procedure.
To describe the complex nonlinear process of laser tissue interactions,a two-dimensional mathematical model considering the dynamic changes in the physical tissue properties was developed here.
Laser-induced interstitial thermotherapy (LITT) performed under MRI guidance results in precise and reproducible areas of induced necrosis with a local control of 94 %, and with an improved survival rate.
The aim of the study was to evaluate the feasibility, safety and effectiveness of CT-guided and MR-thermometry-controlled laser-induced interstitial thermotherapy (LITT) in adrenal metastases.
Laser-induced interstitial thermotherapy (LITT) performed under MRI guidance results in precise and reproducible areas of induced necrosis with a local control of 94 %, and with an improved survival rate.
The aim of the study was to evaluate the feasibility, safety and effectiveness of CT-guided and MR-thermometry-controlled laser-induced interstitial thermotherapy (LITT) in adrenal metastases.