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| | It has been learned that tumor can be cured by heat since 18 th century certain patients with tumor cured after several dayss high fever were reported.Hwever,the method of treating tumor by heating had not been studied and used until 1970s due to te slow development of research in biological thermal effects,temperature monitoring technology and image technilogy.Since 1970s,ultrasound hyperthermia has been greatly developed.The effect of conventional hyperthermia which can elevate the temperature of... | | 早在 18世纪 ,就有肿瘤患者因发高烧而使肿瘤消退的报道 ,但由于生物学、热剂量学加热、测温和影像技术发展缓慢 ,加热治疗肿瘤长期不为人们重视。自上世纪七十年代 ,由于科学技术的突飞猛进 ,特别是计算机、测温、控温、超声学、自动控制等学科的发展 ,使超声加热治疗肿瘤得到相应的发展 ,由常规热疗 (42 .5℃~ 4 5℃ )配合放疗、化疗治疗肿瘤 ,发展到固化热疗 (6 5℃~ 10 0℃ )。固化热疗应用高强度聚焦超声 (HIFU) ,能在短时间内使癌变组织的温度升至 6 5℃以上 ,从而使病变组织凝固、坏死、脱落 ,是一种具有巨大潜力的、无损的、有效的局部治疗手段。本文将对单纯超声热疗 (U) ,单纯 X线放射组 (R) ,先放射后超声加热 (RU) ,先超声加热后放射 (UR)及对照组得出的结果和高强度聚焦超声 (HIFU)固化热疗的有关聚焦换能器原理、方法及临床进行讨论 | | 文摘来源 | | Objective To investigate the therapeutic effects of therapy combined radiation with intracavitary solidifying treatment on nasopharyngeal carcinoma(NPC). Methods Thirty-two cases with NPC were included in this study as treating group and their therapeutic response was compared with that of cases treated simply by radiotherapy.The combined therapy was carried out to the cases with external irradiation given at a dosage of 36 Gy firstly and 50~70 Gy at the total dosage followed after one week of intermittent ... | | 目的探讨体外放射治疗合并微波固化热疗对鼻咽癌的临床治疗价值。方法采用放射治疗合并微波固化热疗对临床32例鼻咽癌患者进行治疗观察,与常规单纯放射治疗进行对比分析。治疗组体外照射36Gy后,采用微波腔内固化一次,瘤体表面温度90±5℃。休息一周继续放疗至总剂量50~70Gy,再给予腔内微波固化1~4次。结果放射合并微波固化热疗对鼻咽癌的疗效比单纯放疗有明显优势。临床疗效显示治疗组完全缓解达75%。结论正确选择适应证并规范操作,放疗合并微波腔内固化治疗鼻咽癌可以获得更好的临床疗效,值得推广。 | | 文摘来源 | |   |
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