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移植肾     
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  renal transplantation
    Application of Color Doppler Power Imaging in Diagnosis of Renal Transplantation Rejection and Its Treatment
    彩色多普勒能量图在移植肾排异反应诊断和治疗中的应用研究
短句来源
    Conclusion Detection of PRA before and after renal transplantation plays a very important role in evaluating outcome of renal transplantation.
    结论 PRA检测对预测移植肾排斥有重要意义
短句来源
  transplanted renal
    Acute transplanted renal rejection occurred in 2 cases in FK506 group and 9 cases in CsA group respectively.
    FK5 0 6组有 2例 (5 .0 % )、CsA组有 9例(15 .5 % )出现经病理证实的急性移植肾排斥反应 ;
短句来源
    Mophological observation and fluorescence antibody staining were performed on the resected transplanted renal samples.
    将切除的移植肾标本行形态学及荧光抗体染色观察 ;
短句来源
    Conclusion FK506 combined with MMF could decrease the occurrence of acute transplanted renal rejection and the dosage of Pred.
    结论 新型免疫抑制剂FK5 0 6与MMF联合应用使急性移植肾排斥反应率降低 ,皮质激素用量减少。
短句来源
  renal transplant
    Clinical Application Studying of MRI for Renal Transplant
    移植肾MRI临床应用研究
短句来源
    The renal sonograms lengths of 43 cases who received renal transplant were studied. It showed that the lengths of the normal renal transplant control group. the AR group and the ATN group were 10. 88±0. 86cm, 12. 75±0. 67cm, 11. 15± 0. 54cm, respectively ;
    本文对43例肾移植患者进行超声观察,结果表明:①正常对照组、急性排异组(AR组)、急性肾小管坏死织(ATN组)的移植肾长径分别为10.83±0.86cm,12.75±067cm,11.15±0.54cm。
短句来源
    4 cases,stenosis of renal transplant artery.
    4例移植肾动脉狭窄。
短句来源
    The approach of comprehension of delayed graft function in renal transplant recipients
    移植肾功能延迟恢复的临床诊治体会
短句来源
    The results showed: (1 ) the length of renal transplant increased by 8. 4% (control group), 28 % (AR group), 12. 5 % (ATN group) over baseline. The increase of AR group was significant (P<0.05) including thickness, volume and cortex thickness of the renes as compared with those of control group (P<0.05 ).
    结果表明; ①肾移植术后,正常对照组、AR组、ATN组移植肾长度均较术前增加,分别为8.4%、28%、12.5%,以AR纷增大明显(P<0.05),AR组的厚径、体积、皮质厚径也较正常对照组增大(P<0.05);
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  transplant renal
    Applied value of color Doppler flow imaging before the interventional treatment for transplant renal artery stenosis
    彩色多普勒超声在移植肾动脉狭窄介入治疗前的应用价值
短句来源
    Methods The quantitative CDFI diagnostic criteria for transplant renal artery stenosis were the peek velocity of main renal artery (Vp)≥200 cm/s,and the acceleration of the intrarenal segmental artery (Ac)≤150 cm/s 2.Four hundred and ten patients after kidney transplantation were detected by CDFI,of which 11 cases who needed interventional treatment underwent further detection to determine the stenostic site and type.
    方法 CDFI以主肾动脉峰值流速 (Vp)≥ 2 0 0cm /s ,肾内段动脉峰速加速度 (Ac)≤ 15 0cm /s2 为诊断肾动脉狭窄量化标准 ,对 410例肾移植患者进行筛选检查并对 11例行介入治疗的移植肾动脉狭窄者进一步确定狭窄部位和类型。
短句来源
    Evaluation of CDFI for Transplant Renal Artery Stenosis interventional treatment
    移植肾动脉狭窄介入治疗的彩色多普勒超声评价
短句来源
    Objective:To ivestigate the applicational value of color Doppler flow imaging(CDFI)technique,which was used to assess the effects of percutaneous transluminal renal angioplasty(PTRA)and percutaneous transluminal renal stenting(PTRAS)for transplant renal stenosis.
    目的 :探讨彩色多普勒血流显像技术 (CDFI)评估移植肾动脉狭窄经皮血管成形术 (PTRA)和支架植入术 (PTRAS)疗效的应用价值。
短句来源
    Methods:Eleven cases with transplant renal artery stenosis underwent CDFI examination before and after interventional treatment followed up every 3~4 months. Statistic method was used to analyse the acceleration of the intrarenal segmental artery(Ac)and the peek velocity of the main renal artery(Vp).
    方法 :对 11例移植肾肾动脉狭窄者于介入治疗前、后行 CDFI检查并每隔 3~4个月随访复查 ,取多普勒参数肾内段动脉血流加速度 (Ac)和主肾动脉峰速度 (Vp)进行统计学分析。
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  renal transplantation
Integrin CD11a/CD18, CD11b/CD18 and CD69 expression in patients after renal transplantation
      
Renal transplantation (RT) is one of the renal replacement therapy options in the terminal stage of chronic renal failure.
      
The expression of integrins was not altered in renal transplantation patients in the current study setting.
      
IL-2, IL-6 and IL-8 levels remain unaltered in the course of immunosuppressive therapy after renal transplantation
      
Cytokines regulate the immune reactions elicited by renal transplantation (RT).
      
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  transplanted renal
We conclude that PTA is the treatment of choice for children with hypertension due to fibromuscular dysplasia and should be attempted for stenosis of the transplanted renal artery.
      
Stenosis was commonly found at the site of the arterial anastomosis of the transplanted renal artery.
      
  renal transplant
The diagnosis of urinary tract infection in renal transplant patients is important because unrecognized bacterial infection may lead - in the worst case - to graft loss.
      
Early diagnosis and successful treatment of acute cytomegalovirus encephalitis in a renal transplant recipient
      
We report the case of a 40-year-old male HIV-negative renal transplant patient with allograft rejection and immunosuppressive therapy who presented with acute cytomegalovirus (CMV) encephalitis.
      
Generalized yersinia enterocolitica infection in a renal transplant patient
      
This report describes a case ofYersinia enterocolitica serotype 0:9 septicaemia in a female renal transplant patient receiving combined immunosuppressive therapy.
      
更多          
  transplant renal
Review of the literature suggests that RAS blockers should be considered as useful agents for treatment of post-transplant hypertension not due to transplant renal artery stenosis.
      
At six months post-transplant renal function is similar in patients receiving CyA and in those receiving azathioprine and steroids.
      
Neither HLA matching, peak panel reactivity, age of the recipient, occurrence of post-transplant renal dysfunction nor 1-month renal function affected the short-term graft outcome.
      
Transplant renal artery stenosis: experience and comparative results between surgery and angioplasty
      
One hundred thirty-eight patients with transplant renal artery stenosis (TRAS) were identified among 1200 patients undergoing renal transplantation in our university hospital.
      
更多          
  其他


PURPOSE 99mTc-DTPA dynamic images of renal transplants were evaluated in dogs, in order to provide a basis for clinical applications. METHODS The 99mTc-DTPA dynamic renal images were performed during the various postoperative periods of the renal allografts in 15 dogs. RESULTS 1. In the stable stage (n = 10), the renal images were clear and the mean K / A index was 3.68 ± 1.18. The B / K indices were > 1 (100%); 2. In the early stage of acute rejection (n = 10), although the renal images were clear, the mean...

PURPOSE 99mTc-DTPA dynamic images of renal transplants were evaluated in dogs, in order to provide a basis for clinical applications. METHODS The 99mTc-DTPA dynamic renal images were performed during the various postoperative periods of the renal allografts in 15 dogs. RESULTS 1. In the stable stage (n = 10), the renal images were clear and the mean K / A index was 3.68 ± 1.18. The B / K indices were > 1 (100%); 2. In the early stage of acute rejection (n = 10), although the renal images were clear, the mean K / A index was 1 .98 ± 0. 17 (P< 0.01), the rate of tracer elimination from the renal allograft was obviously delayed, and the B / K indices were < 1 (100%); 3. In the advanced stage of acute rejection (n= 10), the renal images were obviously faint and dim, and the bladder was not shown. We also performed 99mTc-DTPA dynamic renal images in 8 renal transplant patients. Normal images were observed in 3 cases,including 1 heterotopic renal autograft patient suffering from renovascular hypertension, I renal allograft patient whose renal function was stable, and I patient with early stage of acute rejection which was reversed by the "pulse therapy" of large doses of glucocorticoid for 3 days, but the serum Cr had not returned to normal. Four patients with acute rejection including 2 mild and 2 severe cases, whose renal dynamic images were identified as the early rejection and the advanced rejection respectively when compared with the above animal experiments. One patient with urinary obstruction showedan obstructed pattern of the function curve while the perfusion of the graft kidney remained normal.CONCLUSIONS In 99mTc-DTPA dynamic renal images, B / K index can precisely detect any disturbance of renal function in the early stage of acute rejection; whereas the K / A index, which reflects the renal blood perfusion, can indicate the seventy of rejection. It can also serve as a parameter to indicate the curative effect of anti-rejection treatment,more sensitive than the change of serum Cr, and to discriminate urinary obstruction as well.

通过狗异体肾移植动态肾显像的研究,为临床应用提供依据.方法:建立标准狗异体肾移植模型,以99mTc-DTPA为示踪剂,对15条狗异体肾移植后进行肾动态显像监测.结果:稳定期(n=10)肾显像清晰,移植肾高峰计数/主动脉高峰计数(K/A)均值3.65±1.18.20分钟膀胱/移植肾放射性计数(B/K))比值>1(100%);排异早期(n=10)肾显像清晰.K/A均值1.98±0.67(P<0.01),肾清除核素速率明显降低,B/K比值<1(100%);排异晚期(n=10)肾显像差,膀胱不显像.临床检查8例肾移植病人,正常肾动态显像3例,包括1例自体肾移植和1例异体肾移植,两者肾功能均正常,1例急性排异早期,用大剂量糖皮质激素冲击疗法3天,肾恢复利尿但血Cr尚未恢复正常;异常肾动态显像5例,其中2例急性排异病情较轻和2例严重急性排异病人,肾动态显像表现分别与上述动物实验的排异早、晚期的异常显像相符,1例并发急性尿路梗阻病人移植肾血流灌注正常,排泄受阻,功能相呈梗阻型.结论:99mTc-DTPA肾动态显像的B/K比值能发现早期排异的肾功能异常,K/A比值反映肾血流灌注情况.与排异...

通过狗异体肾移植动态肾显像的研究,为临床应用提供依据.方法:建立标准狗异体肾移植模型,以99mTc-DTPA为示踪剂,对15条狗异体肾移植后进行肾动态显像监测.结果:稳定期(n=10)肾显像清晰,移植肾高峰计数/主动脉高峰计数(K/A)均值3.65±1.18.20分钟膀胱/移植肾放射性计数(B/K))比值>1(100%);排异早期(n=10)肾显像清晰.K/A均值1.98±0.67(P<0.01),肾清除核素速率明显降低,B/K比值<1(100%);排异晚期(n=10)肾显像差,膀胱不显像.临床检查8例肾移植病人,正常肾动态显像3例,包括1例自体肾移植和1例异体肾移植,两者肾功能均正常,1例急性排异早期,用大剂量糖皮质激素冲击疗法3天,肾恢复利尿但血Cr尚未恢复正常;异常肾动态显像5例,其中2例急性排异病情较轻和2例严重急性排异病人,肾动态显像表现分别与上述动物实验的排异早、晚期的异常显像相符,1例并发急性尿路梗阻病人移植肾血流灌注正常,排泄受阻,功能相呈梗阻型.结论:99mTc-DTPA肾动态显像的B/K比值能发现早期排异的肾功能异常,K/A比值反映肾血流灌注情况.与排异的严重程度相关;该检查还能早期反映抗?

The renal sonograms lengths of 43 cases who received renal transplant were studied. It showed that the lengths of the normal renal transplant control group. the AR group and the ATN group were 10. 88±0. 86cm, 12. 75±0. 67cm, 11. 15± 0. 54cm, respectively ; RI of cortex artery was 0. 66±0. 04 in control group, 0. 87± 0. 07 in AR group,and 0. 81±0. 06 in ATN group. Both the AR and ATN group showed obviously higher RI than the control group. Some echographic signs were perceived in AR patients, including hyperechogenicity...

The renal sonograms lengths of 43 cases who received renal transplant were studied. It showed that the lengths of the normal renal transplant control group. the AR group and the ATN group were 10. 88±0. 86cm, 12. 75±0. 67cm, 11. 15± 0. 54cm, respectively ; RI of cortex artery was 0. 66±0. 04 in control group, 0. 87± 0. 07 in AR group,and 0. 81±0. 06 in ATN group. Both the AR and ATN group showed obviously higher RI than the control group. Some echographic signs were perceived in AR patients, including hyperechogenicity of the renal cortex, decreased renal sinus area with hypoechogenicity, and thickening of the collecting system. During AR Period, RI problems usually resolved in about 5-7days'antirejection therapy, while ATN needed 10-14 days.

本文对43例肾移植患者进行超声观察,结果表明:①正常对照组、急性排异组(AR组)、急性肾小管坏死织(ATN组)的移植肾长径分别为10.83±0.86cm,12.75±067cm,11.15±0.54cm。AR组长径大于正常对照组(P<0.05),ATN组长径与对照组无统计学差异。②正常对照组、AR组、ATN组的皮质部RI值分别为:O.66±0.04,0.87±0.07,0.81±0.06。AR组和ATN组RI均明显高于对照组,但AR组和ATN组间无统计学差异(P>0.05)。③AR组可观察到肾皮质回声增强,肾窦回声减低、面积缩小,集合系统粘膜增厚等表现。④经抗排异治疗后,AR组RI值约5~7大恢复正常,而ATN组则需10~14天。

The model of renal transplantation in goat was mads. 18 goats were divided onto three groups: (1) con-trol group; (2) acute tubular necrosis (ATN ) group ; (3 ) acute rejection (AR) group, both group (1) and (2 ) had heterotopic autotransplantation in the neck, group (3) had heterotopic allografting in the same site. The results showed: (1 ) the length of renal transplant increased by 8. 4% (control group), 28 % (AR group), 12. 5 % (ATN group) over baseline. The increase of AR group was significant (P<0.05)...

The model of renal transplantation in goat was mads. 18 goats were divided onto three groups: (1) con-trol group; (2) acute tubular necrosis (ATN ) group ; (3 ) acute rejection (AR) group, both group (1) and (2 ) had heterotopic autotransplantation in the neck, group (3) had heterotopic allografting in the same site. The results showed: (1 ) the length of renal transplant increased by 8. 4% (control group), 28 % (AR group), 12. 5 % (ATN group) over baseline. The increase of AR group was significant (P<0.05) including thickness, volume and cortex thickness of the renes as compared with those of control group (P<0.05 ). (2) RI of cortex ateries in AR and ATN group were relatively higher than those of the control group (P<0.01), the RI peak time of AR group was earlier than that of ATN group. (3) Early period after acute rejection, peak systolic velocity obviously increased. (4) Color Doppler energy as a method of evaluating the blood perfusion of renal cortex was superior to color Doppler flow imaging.

本研究用山羊建立肾移植模型,分为三组:(1)正常对照组;(2)急性肾小管坏死组(ATN);(3)急性排异组(AR),每组6只。前两组采用自体肾移植,AR组采用同种异体肾移植。结果表明;①肾移植术后,正常对照组、AR组、ATN组移植肾长度均较术前增加,分别为8.4%、28%、12.5%,以AR纷增大明显(P<0.05),AR组的厚径、体积、皮质厚径也较正常对照组增大(P<0.05);②AR组和ATN级皮质部RI均高于正常对照组(P<0.01),ATN组RI峰值时间早于AR组;③AR组排异早期,肾皮质动脉峰值流速增快;④彩色多普勒能量图评价肾皮质血流灌注明显优于彩色多普勒血流显像。

 
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