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营养传感器
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  “营养传感器”译为未确定词的双语例句
     O-linked β-N-acetyglucosamine(O-GlcNAc),a newly identified post-translational modification,widely occurs in nuclear and cytoplasmic proteins. O-GlcNAc transferase and O-GlcNAcase are responsible for the addition and removal of O-GlcNAc from serine/threonine residues,respectively. Based on some well-studied proteins,this modification might interplay with O-phosphorylation directly or indirectly.
     N-乙酰葡萄糖胺(O-G lcNAc)修饰是一种新鉴定的蛋白质糖基化方式,在细胞内分布广泛,通过糖基转移酶和糖苷酶将N-乙酰葡萄糖胺单糖添加或移除到蛋白质的丝/苏氨酸残基上,并可能与磷酸化存在直接或间接的相互影响,参与转录调控、信号转导、蛋白酶解等多种重要保守的生命活动,从而发挥营养传感器和压力感受器的作用,调节细胞对外界刺激的反应。
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  相似匹配句对
     Sensors
     传感器
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     SENSOR
     浅谈传感器
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     Environmental Nutrition
     环境营养
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     the nutritional function;
     营养作用 ;
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  nutrient sensor
A role for N-acetylglucosamine as a nutrient sensor and mediator of insulin resistance
      
As one example, we are very interested in deploying nutrient sensor systems on such a mooring.
      
Whereas PI3K is responsive to growth factors, TOR has been proposed to be a cellular nutrient sensor.
      


O-linked β-N-acetyglucosamine(O-GlcNAc),a newly identified post-translational modification,widely occurs in nuclear and cytoplasmic proteins.O-GlcNAc transferase and O-GlcNAcase are responsible for the addition and removal of O-GlcNAc from serine/threonine residues,respectively.Based on some well-studied proteins,this modification might interplay with O-phosphorylation directly or indirectly.O-GlcNAc is implicated in some important cellular processes such as regulation of gene expression,signal transduction...

O-linked β-N-acetyglucosamine(O-GlcNAc),a newly identified post-translational modification,widely occurs in nuclear and cytoplasmic proteins.O-GlcNAc transferase and O-GlcNAcase are responsible for the addition and removal of O-GlcNAc from serine/threonine residues,respectively.Based on some well-studied proteins,this modification might interplay with O-phosphorylation directly or indirectly.O-GlcNAc is implicated in some important cellular processes such as regulation of gene expression,signal transduction and protein proteolysis.Thus it is suggested that this modification functions as a nutrient sensor or a stress sensor in response to extracellular stimuli.Moreover,recent researches showed that O-GlcNAc modification is closely related to the etiology of type 2 diabetes and neurodegenerative diseases.

N-乙酰葡萄糖胺(O-G lcNAc)修饰是一种新鉴定的蛋白质糖基化方式,在细胞内分布广泛,通过糖基转移酶和糖苷酶将N-乙酰葡萄糖胺单糖添加或移除到蛋白质的丝/苏氨酸残基上,并可能与磷酸化存在直接或间接的相互影响,参与转录调控、信号转导、蛋白酶解等多种重要保守的生命活动,从而发挥营养传感器和压力感受器的作用,调节细胞对外界刺激的反应。同时有研究表明,2型糖尿病和老年神经退行性疾病与O-G lcNAc修饰水平的升高和降低也有密切关系。

 
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