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肝纤维化
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  liver fibrosis
    The Content Changes of Serum Liver Fibrosis Indicators after Transarterial Chemoembolization for Primary Hepatic Carcinoma and Their Clinical Significance
    肝癌化疗栓塞后血清肝纤维化指标的含量变化及临床意义
短句来源
    The Significance of The Measurement of Serum Fibrosis Markers in Liver Fibrosis for The Hepatocellular Carcinoma
    原发性肝癌患者血清肝纤维化指标检测的意义
短句来源
    Objective To develop a radioimmunoassay (RIA) of type Ⅳ collagen (CⅣ) for diagnosis of liver fibrosis and cirrhosis.
    目的建立血清Ⅳ型胶原(CⅣ)放射免疫测定法,辅助诊断肝纤维化及肝硬化。
短句来源
    Conclusions TNF α is able to induce the expression of CTGF in HSC, and this may be one of the mechanisms for TNF α involving in the liver fibrosis.
    结论 TNF α可诱导 HSC的 CTGF mRNA表达,可能是其参与早期肝纤维化形成的作用机理之一。
短句来源
    Conclusion:During the occurrence and development of liver cirrhosis and HCC,TGF-β 2 and TNF-α are two important cytokines implicated as important pathogenic mediators in the development of liver fibrosis and HCC.
    结论细胞因子TGF-β2,TNF-α在HBV感染后肝纤维化及肝癌的形成及发展过程中起一定作用。
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  hepatic fibrosis
    Pathological Observation of Schistosomiasis Hepatic Fibrosis Coincident with Hepatocellular Carcinoma
    血吸虫病肝纤维化并发肝细胞癌的病理观察
短句来源
    Objective To evaluate the clinical effect and the indexes of hepatic fibrosis by TACE (Transcather arterial chemoembolization) with different chemotherapy dose in advanced hepatic carcinoma.
    目的:对比观察不同化疗药物剂量经动脉导管灌注化疗栓塞术(transcather arterial chemoembolization,TACE)治疗原发性肝癌的疗效及对肝纤维化指标的影响。
    PATHOLOGICAL OBSERVATION OF SCHISTOSOMIASIS HEPATIC FIBROSIS COINCIDENT WITH HEPATOCELLULAR CARCINOMA
    血吸虫病肝纤维化并发肝细胞癌的病理观察
短句来源
    Effect of Hepatic Fibrosis on Liver Metastasis in Cancer of Colon and It's Mechanisms
    肝纤维化对结肠癌肝转移的影响及其作用机制的研究
短句来源
    1.3 Construction of liver metastasis model:After the formation of hepatic fibrosis,we divided randomly GA mice into two groups:normal liver group(group A1, GA1) and normal liver inoculated with CT26 group (group A2,GA2);
    1.3转移癌模型的构建:肝纤维化模型制成后,将A组和B组小鼠再分别分为两组,即A1组(正常肝组)、A2组(正常肝种瘤组)、B1组(肝纤维化组)和B2组(肝纤维化种瘤组),每组16只小鼠。
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  “肝纤维化”译为未确定词的双语例句
    Methods:Twenty hepatic fibrotic rabbit models were randomly divided into the HGF group(n=10) and control group(n=10).
    方法:20只肝纤维化新西兰大白兔模型,随机分为两组(HGF组,对照组),每组各10只。
短句来源
    A Sutdy of Three Intervention Therapies Influence on the Five Hepatofibrosis Indexes of Middle and Advanced Hepatocellular Carcimona Serum
    三介入治疗对中晚期肝癌血清五项肝纤维化指标影响的研究
短句来源
    27 cases of viral-induced cirrhosis with Child-Pugh A, 23 cases of viral-induced cirrhosis with Child-Pugh B, 15 cases of viral-induced cirrhosis with Child-Pugh C.
    正常对照组34例,肝炎肝纤维化组21例,肝硬化Child-Pugh A级27例,肝硬化Child-Pugh B级23例,肝硬化Child-Pugh C级15例; 共5组120例。
短句来源
    Result HSP47-positive cells were observed in the capsule of HCC and the fibrous septa of fibrostic liver around HCC.
    结果 人肝癌包膜、癌旁肝纤维化纤维间隔内的纤维细胞以及在纤维间隔附近肝细胞周围的星状细胞表达HSP47蛋白。
短句来源
    the expression of TGF-β1 and smad4 mRNA in pare-cancerous tissues were significantly lower than that in the chronic virus hepatitis and hepatocirrhosis, as comparied with with the normal liver;
    而癌旁肝组织二者的表达均低下,与对照组无明显差异; 随着肝纤维化的发展TGF-β1和smad4mRNA的表达呈逐渐增强趋势,S3期达高峰,S4期有所回落;
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  liver fibrosis
Conversely, HAART-related hepatotoxicity may enhance the progression of liver fibrosis.
      
Objective: To study the effect of Xuesaitong soft capsule (XST) on liver fibrosis criteria in patients with post-hepatitis fibrosis.Methods: Sixty-four patients with such fibrosis were randomly divided into the treated group and control group.
      
Their liver fibrosis criteria were examined before and after treatment.Results: The levels of serum procollagen III, hyaluronic acid, collagen IV, laminin in the two groups were significantly lower (P>amp;lt;0.
      
The differences between the two groups were insignificant (P>amp;gt;0.05).Conclusion: XST could recover liver dysfunction and had anti-liver fibrosis function.
      
However, response rates are much lower in patients who are difficult to treat, such as those infected with hepatitis C virus genotype 1, high viral load, or advanced liver fibrosis.
      
更多          
  hepatic fibrosis
The Ile50Val polymorphism of the IL4RA gene was tested for association with chronic viral hepatitis and the character of its progression (the stage of hepatic fibrosis).
      
However, a significant difference in genotype frequency distribution was observed for the patients with different stages of hepatic fibrosis.
      
In hepatic fibrosis, the connective tissue biomatrix of the liver changes from the normal matrix, rich in basement membrane collagens, to a matrix enriched in interstitial fibrillar collagens.
      
Viral hepatitis, hepatic fibrosis and hepatocirrhosis etc.
      
Clinical study of Dahuang Zhechong pill in treating posthepatitis B hepatic fibrosis
      
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By histochemical methods of AKPase, ACPase, 5'-Nase, NSE and SDH, 10 cases of human hepatocellular carcinoma (HCC) and its surrounding liver tissue were investigated. Generally, these enzyme activities in HCCs obviously decreased or completely disappeared, neverthless in one case, the AKPase of HCC showed notable activity, and in another case, the ACPase activity also marked.The surrounding liver tissue either in cirrhosis or in hepatic fibrosis appeared normal hepatic enzymatic activity. The differences of...

By histochemical methods of AKPase, ACPase, 5'-Nase, NSE and SDH, 10 cases of human hepatocellular carcinoma (HCC) and its surrounding liver tissue were investigated. Generally, these enzyme activities in HCCs obviously decreased or completely disappeared, neverthless in one case, the AKPase of HCC showed notable activity, and in another case, the ACPase activity also marked.The surrounding liver tissue either in cirrhosis or in hepatic fibrosis appeared normal hepatic enzymatic activity. The differences of enzymes between HCCs and their surrounding liver tissues were distinct.

本文用碱性和酸性磷酸酶、5′-核苷酸酶、非特异性酯酶和琥珀酸脱氢酶的组织化学方法观察了10例人体肝细胞癌和癌周肝组织的变化。一般来说,肝细胞上述酶的活性明显减弱至消失,仅见一例碱性磷酸酶和另一例酸性磷酸酶呈现明显活性。而癌周肝组织无论是肝硬化或肝纤维化均显示正常肝细胞的酶活性。癌和癌周肝具有明显的酶的差异性。

Congenital cystic dilatation of the intrahepatic ducts (Caroli' s disease) until recently has been rarely reported in the Chinese literature. 19 patients with this condition are reported from the experience of the surgeons and roentgenologists at the First Affiliated Hospital of the Sun Yat-sen University of Medical Sciences, together with a review of the world literature.

先天性肝内胆管囊性扩张症(Caroli病)在我国至今仅有37例,其中成人型者仅14例。本文报告19例,并作文献复习。Caroli将本病分为两型:①单纯型(Ⅰ型):以反复发作胆道感染为特点;②汇管区周围纤维化型,又称Ⅱ型。Caroli称本病Ⅰ型极少见。我国及本组材料则相反,以Ⅰ型占大多数。本病与肝胆管结石梗阻导致继发性肝内胆管扩张有时难以区别。由于本病累及双侧肝叶较多,故切除病变机会较少。病理学家对本病的病理组织学特点认识也不够。国外对本病Ⅱ型与先天性肝纤维化的关系认识意见亦相当混乱。因此,目前对本病诊断,主要依靠胆管造影所显示的肝内胆管形态。近年文献报告本病有恶性病变倾向,恶变率约为7%。

Chondroitin sulfate(CS)in human normal liver,cirrhotic liver and hepatocellu-lar carcinoma(HCC)was studied with PAP immunohistochemical method,CS wasprescnt in various liver cells ,on the surfaces of hepatic plates and in extracellularmatrix in normal liver,Much more CS was found in connective tissues of cirrho- tic liver and HCC. The latter one might be a carcinoembryonic phenomenon,whichcould stimulate growth,infiltration and metastas is of tumor.

本文应用PAP免疫组织化学法测定人正常肝脏、肝硬化及肝细胞癌组织中的硫酸软骨素(ChondroitinSulfate,CS),发现正常肝脏中CS多散在分布于肝脏细胞中和肝板表面,肝硬化组织中假小叶的纤维间隔和细胞外间质中CS大量不均匀分布,肝细胞癌组织亦见CS分布范围扩大,在癌细胞周围结缔组织中大量存在。提示:肝纤维化或癌变时伴随CS的大量合成和胞外沉积,对前者是参与纤维组织过度增生的重要因素,对后者可能是一种癌胚现象,与癌细胞增殖、浸润和转移有关。

 
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