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三甲基吲哚
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  3-methylindole
     Study on Chromatogram Analysis of 3- Methylindole
     三甲基吲哚的气相色谱分析方法研究
短句来源
     A gas chromatogram method to detect 3- methylindole content is est ablished.
     建立了三甲基吲哚的气相色谱含量测定分析方法。
短句来源
  “三甲基吲哚”译为未确定词的双语例句
     When the sample concentra tion and internal standard quality concentration are 5~ 25 mg/mL,2 mg/mL ~ 10 mg/mL respectively, it shows good linearity with peak area, relative coefficient R=0.999. Relative standard deviation is between 0.15% ~ 0.20% .
     样品和内标质量浓度分别为5~25mg/mL,2~10mg/mL时与峰面积呈良好的线性关系,相关系数R=0.999以上。 三甲基吲哚的相对标准偏差在0.15%~0.20%之间。
短句来源
     Pharmacokinetics of 5-(1, 3, 3-trimethylindolinyl)N,N- dimethyl carbamate and its metabolites inthe isolated perfused rat livers
     N,N-二甲氨基甲酸5-(1,3,3-三甲基吲哚满)酯及其代谢产物在大鼠离体肝脏中的代谢动力学
短句来源
     Comparison of f acilitatory effects of 5-(1, 3, 3-trimethylindolinyl) N, N-dimethyl carbamate and physostigmine onthe performance of visual cueing spatial discriminationin mice
     N,N-二甲氨基甲酸5-(1,3,3-三甲基吲哚满)酯与毒扁豆碱促进小鼠视觉暗示空间鉴别学习和记忆的比较
短句来源
     Using phenylhydrazine and 3-methyl-2-butanone as main materials,2,3,3-tri-methyl-3H-indole was prepared,after quaterizing with iodomethane,reacting with 2-hydroxy-1-naphthaldehyde under basic condition,the target compound 1,3,3-trimethylindolinespironaphthooxazine was got.
     以苯肼、3-甲基-2-丁酮为原料合成得到2,3,3-三甲基-3H-吲哚,经碘甲烷季铵盐化后在碱性条件下与1-亚硝基-2-萘酚反应得到1,3,3-三甲基吲哚啉螺萘并口恶嗪光致变色化合物。
短句来源
     Five new substituted indocarbocyanine dyes with N- sulfonic acid moiety were synthesized by refluxing a selected 1-(3'-sulfopropyl)-2, 3, 3-trimethyl-indolenine salt with etheyl orthoformate in pyridine or acetic anhydride.
     将(未)取代的1-(3′-磺酸丙基)-2,3,3-三甲基吲哚啉内盐与原乙酸三乙酯在吡啶或酸酐中回流合成了五个氮原子上带有磺酸丙基的取代吲哚碳菁染料。
短句来源
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  相似匹配句对
     Three.
     .
短句来源
     三.
     .
短句来源
     Study on Chromatogram Analysis of 3- Methylindole
     甲基吲哚的气相色谱分析方法研究
短句来源
     A gas chromatogram method to detect 3- methylindole content is est ablished.
     建立了甲基吲哚的气相色谱含量测定分析方法。
短句来源
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  3-methylindole
Exploratory activity of mice of different genetic strains after olfaction disruption by 3-methylindole (skatole)
      
The behavior of mice of two inbred strains (C57BL/6J and CBA) and their F1 hybrids was evaluated in the open field test after intraperitoneal administration of 3-methylindole (skatole) disrupting epithelium of the main olfactory system.
      
Reactions of indole, 1-methylindole, and 3-methylindole with dimethyl acetylenedicarboxylate in the presence of K10 montmorillonite as a catalyst led to the formation of the corresponding dimethyl 2,2-bis(indolyl)butanedioates.
      
Application of LC-MS for Determination of Indole and 3-Methylindole in Porcine Adipose Tissue
      
A new method is described for simultaneous determination of 3-methylindole (3MI) and indole in porcine adipose tissue.
      
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Fordine, a reversible ChE inhibitor with a new structure, acts as a potent cholinomimetic drug. In vitro, the inhibitory potency of fordine on mouse brain or erythrocyte AChE and on porcine brain immobilized AChE was thousand times higher than that on BuChE in the blood and serum of mouse. In vivo, the recovery of mouse AChE inhibited by fordine was significantly delayed than that inhibited by CuiXingNing. The inhibition of ChE by fordine showed a mixed pattern of both competitive and non-competitive inhibitions....

Fordine, a reversible ChE inhibitor with a new structure, acts as a potent cholinomimetic drug. In vitro, the inhibitory potency of fordine on mouse brain or erythrocyte AChE and on porcine brain immobilized AChE was thousand times higher than that on BuChE in the blood and serum of mouse. In vivo, the recovery of mouse AChE inhibited by fordine was significantly delayed than that inhibited by CuiXingNing. The inhibition of ChE by fordine showed a mixed pattern of both competitive and non-competitive inhibitions. Fordine showed a higher selective inhibition on AChE than on BuChE.

福定碱是一新结构类型的可逆性胆碱酯酶抑制剂。它具有较强的拟胆碱作用。对小鼠脑、红细胞和猪脑固相胆碱酯酶(AChE)的抑制强度为对血浆胆碱酯酶(BuChE)抑制强度的数千倍。体内对小鼠AChE的抑制时间远比氨基甲酸酯类化合物催醒宁(二甲氨基甲酸-5-(1,3,3-三甲基)吲哚满酯盐酸盐(TIDC)长。抑酶方式属竞争和非竞争性的混合型抑制。

The pharmacokinetics of 5 (1, 3, 3-trimethylindolinyl) N, N-dimethyl carbamate (TMDMC) and its metabolites were studied in the isolated perfused rat livers. The livers were perfused with TMDMC dissolved in a modified Krebs-Henseleit solution. The concentration of TMDMC and its metabolites from the perfusates were measured by HPLC. The results showed that the pharmacokinetics of TMDMC in the perfused liver corresponded to the two-compartment model. TMDMC in the perfusate was quickly eliminated as the perfusate...

The pharmacokinetics of 5 (1, 3, 3-trimethylindolinyl) N, N-dimethyl carbamate (TMDMC) and its metabolites were studied in the isolated perfused rat livers. The livers were perfused with TMDMC dissolved in a modified Krebs-Henseleit solution. The concentration of TMDMC and its metabolites from the perfusates were measured by HPLC. The results showed that the pharmacokinetics of TMDMC in the perfused liver corresponded to the two-compartment model. TMDMC in the perfusate was quickly eliminated as the perfusate passed throughthe liver with a t1 /2 a of 4 min and a Ⅵ of 102 ml in 20 min. By 2 h perfusion, the concentration of TMDMC reduced 73%. In the meanwhile, the metabolites, especially metabolite Ⅲ , were gradually formed. The maximal concentration of metabolite Ⅲ was about 477 μg·ml-1. The results suggest that the liver is one of the main organs which metabolize TMDMC.

利用大鼠肝脏灌流技术研究了N,N-二甲氨基甲酸5-(1,3,3-三甲基吲哚满)酯(TMDMC)及其代谢产物在大鼠离体肝脏中的代谢动力学,TMDMC在改良的灌流液中作循环式灌流,于不同时间留取少量灌流液,用高效液相色谱(HPLC)作药物的定量分析,结果显示其在离体灌流肝脏中的清除模型符合两相消除模型,动力学参数表明,TMDMC在肝内的分布较快,其分布半衰期仅为4min,肝脏分布容积为102.4 ml,清除率是0.67ml·min~(-1),清除比率为0.027.灌流2h时,其浓度已下降了73%.与此同时,TMDMC的代谢产物逐渐生成,其中以产物Ⅲ的生成量最大,其最高生成浓度(C_(max))为447.1 μg·ml~(-1),2 h产物Ⅲ的生成总量已达TMDMC灌流量的25.6%.而代谢产物Ⅱ,Ⅵ的生成较少,其C_(max)分别是20.4μg·ml~(-1)和20.7μg·ml~(-1).

Five new substituted indocarbocyanine dyes with N- sulfonic acid moiety were synthesized by refluxing a selected 1-(3'-sulfopropyl)-2, 3, 3-trimethyl-indolenine salt with etheyl orthoformate in pyridine or acetic anhydride. In comparison with the N-alkyl partner these dyes exhibit higher melting points and higher solubility in polar solvent. Absorption maxima of these dyes are in the range 540- 580nm with higher extinction coefficient (1- 2×105L · mol-1· cm-1).

将(未)取代的1-(3′-磺酸丙基)-2,3,3-三甲基吲哚啉内盐与原乙酸三乙酯在吡啶或酸酐中回流合成了五个氮原子上带有磺酸丙基的取代吲哚碳菁染料。这些染料和杂环氮原子上带有烷基取代的吲哚碳菁相比,它们具有较高的熔点,在极性溶剂中具有较高的溶解度。这些染料的最大吸收值在540~580nm之间,并具有较高的消光系数(1~2×10~5L·mol~(-1)·cm~(-1))。

 
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