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膀胱癌    
相关语句
  bladder
    It was indicated through in vitro biological assays by using MTT that the title compound exhibited higher inhibitory effect on the malignant proliferation of bladder cancer cell T-24 and stomach cancer cell BGC-823 than tegafur,but on the other hand it showed a higher toxicity on the normal liver epithelial cell L-02.
    体外细胞毒性试验结果表明:产物对膀胱癌细胞T-24、胃癌细胞BGC-823的恶性增殖抑制效果优于替加氟; 但对正常肝上皮细胞毒性也大于替加氟.
短句来源
  bladder cancer
    It was indicated through in vitro biological assays by using MTT that the title compound exhibited higher inhibitory effect on the malignant proliferation of bladder cancer cell T-24 and stomach cancer cell BGC-823 than tegafur,but on the other hand it showed a higher toxicity on the normal liver epithelial cell L-02.
    体外细胞毒性试验结果表明:产物对膀胱癌细胞T-24、胃癌细胞BGC-823的恶性增殖抑制效果优于替加氟; 但对正常肝上皮细胞毒性也大于替加氟.
短句来源
  bladder cancer
    It was indicated through in vitro biological assays by using MTT that the title compound exhibited higher inhibitory effect on the malignant proliferation of bladder cancer cell T-24 and stomach cancer cell BGC-823 than tegafur,but on the other hand it showed a higher toxicity on the normal liver epithelial cell L-02.
    体外细胞毒性试验结果表明:产物对膀胱癌细胞T-24、胃癌细胞BGC-823的恶性增殖抑制效果优于替加氟; 但对正常肝上皮细胞毒性也大于替加氟.
短句来源
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  bladder
EGFR is over-expressed in numerous tumors including, those derived from the brain, lung, bladder, head and neck.
      
Intra-abdominal pressure (IAP) was measured in the first three days after surgery by using the urinary bladder technique.
      
Study of recombinant human IFN-α-2b bacilli calmette-guerin activated killer cells and against bladder cancer cell in vitro
      
Presently, one of the most potent immunotherapies is the application of bacillus Calmette Guerin (BCG) to prevent recurrences of the superficial bladder cancer.
      
BAK cells have the ability to kill bladder tumor cells, and the antitumor activity of effecter cells was determined by LDH release assay.
      
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  bladder cancer
Study of recombinant human IFN-α-2b bacilli calmette-guerin activated killer cells and against bladder cancer cell in vitro
      
Presently, one of the most potent immunotherapies is the application of bacillus Calmette Guerin (BCG) to prevent recurrences of the superficial bladder cancer.
      
We conclude that the recombinant BCG can activate more PBMCs to anti-bladder cancer in vitro than wild-type BCG does.
      
Radiotherapy is an Effective Treatment for High-Risk T1-Bladder Cancer
      
We have evaluated the efficacy of adjuvant radiotherapy or radiochemotherapy on local control, bladder preservation, recurrence rate and long-term survival after TURB of high-risk T1-bladder cancer.
      
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  bladder carcinoma
TBARS, Carnitine, and Reduced Glutathione Levels in Human Bladder Carcinoma
      
In this study, we investigated tissue levels of reduced glutathione (GSH) and carnitine as well as thiobarbituric acid reactive substances (TBARS, as a marker of lipid peroxidation) levels in bladder carcinoma and control group of patients.
      
Cefoperazone was administered to 50 of 139 in-patients suffering from urinary tract infections complicated by underlying diseases such as prostatic adenoma or carcinoma, bladder carcinoma, ureterolithiasis or epididymitis.
      
Expression of a mutant hTERT in human bladder carcinoma cell line T24 and its clinical significance
      
After transfecting the fusion gene into bladder carcinoma cell line T24 by calcium phosphate-DNA coprecipitation, the steady expression of GFP-hTERT fusion protein was tested by fluorescent light microscopy.
      
更多          
  bladder cancer
Study of recombinant human IFN-α-2b bacilli calmette-guerin activated killer cells and against bladder cancer cell in vitro
      
Presently, one of the most potent immunotherapies is the application of bacillus Calmette Guerin (BCG) to prevent recurrences of the superficial bladder cancer.
      
We conclude that the recombinant BCG can activate more PBMCs to anti-bladder cancer in vitro than wild-type BCG does.
      
Radiotherapy is an Effective Treatment for High-Risk T1-Bladder Cancer
      
We have evaluated the efficacy of adjuvant radiotherapy or radiochemotherapy on local control, bladder preservation, recurrence rate and long-term survival after TURB of high-risk T1-bladder cancer.
      
更多          


Four analogues and three segments were designed and synthesized by using solidphase peptide synthesis method according to separated papaver somniferum pollen heptade-capeptide with promoting immunity and antitumor activities as the leading compound. Theirprimary secondary structures in solution were determined by CD spectra and their inhibitiveactivities to human gastric and bladder cancer cells were assayed by MTT method. The rela-tionship of structure-activity was preliminarily discussed.

以从罂粟花粉中分离得到的具有促免疫和抗肿瘤活性的十七肽为先导化合物,设计了4个类似物和3个片段,并用固相法合成,通过CD谱测定了它们在溶液中的初级二级结构,同时测定了它们对人胃癌和人膀胱癌肿瘤细胞的抑制活性,初步讨论了构效关系.

The complexes \[Pt(II)(H\-2O)\-2(OOC-CH\-2NH\-2)\-2\](1) and \[Pt(II)(H\-2O)\-2(OOC-CHCHCOO)\](2) were synthesized for the first time. They were characterized by elemental analysis, molar conductance, differential thermal analysis and spectral(IR, UV, 1HNMR) studies. The results indicated that the complexes (1-2) have poor activities against human tumor cell lines in vitro and the inhibitory ratios against EJ are 25.77%和28 27% at concentration of 10 μM, respectively.

首次合成两种二水羧酸根合铂类配合物[Pt(II) (H2 O) 2 (OOC—CH2 NH2 ) 2 ](1)和[Pt(II) (H2 O) 2 (OOC—CH=CHCOO) ](2 ) .用元素分析、摩尔电导、差热热重分析、红外光谱、紫外光谱和核磁共振氢谱对其进行了表征.体外抗肿瘤活性表明,两种配合物对所试的肿瘤细胞表现出较低的活性,在10 μM浓度下配合物对人膀胱癌细胞EJ的增殖抑制率分别为2 5 .77%和2 8.2 7% .

2-Phthalimidoethyl-2-sulfur-1,3,2-dioxaphopholane(1) and cyclic glycerothiophospholipid conjugate of phahalimidoethanol(2) were used as model compounds to investigate the selectivity and reaction conditions of nucleophilic opening ring by heteroatomic function groups.CH-3OH could attack the phosphor atom in 1,3,2-dioxaphopholane of compiound(1) to give O-methyl O-hydroxyethyl-O-phthalimidoethyl thiophosphate in 85% yield;in the presence of potassium hydroxide aryl selenol could attack the carbon atom in 1,3,2-dioxaphopholane...

2-Phthalimidoethyl-2-sulfur-1,3,2-dioxaphopholane(1) and cyclic glycerothiophospholipid conjugate of phahalimidoethanol(2) were used as model compounds to investigate the selectivity and reaction conditions of nucleophilic opening ring by heteroatomic function groups.CH-3OH could attack the phosphor atom in 1,3,2-dioxaphopholane of compiound(1) to give O-methyl O-hydroxyethyl-O-phthalimidoethyl thiophosphate in 85% yield;in the presence of potassium hydroxide aryl selenol could attack the carbon atom in 1,3,2-dioxaphopholane of the cyclic phospholipid conjugate of N~1-(2-furanidyl)-N~3-(hydroxyalkyl)-5-fluorouracil to give the corresponding product of ring-opening in high yields.It was indicated through in vitro biological assays by using MTT that the title compound exhibited higher inhibitory effect on the malignant proliferation of bladder cancer cell T-24 and stomach cancer cell BGC-823 than tegafur,but on the other hand it showed a higher toxicity on the normal liver epithelial cell L-02.

以O-(2-邻苯二甲酰亚氨基)乙基-1,3,2-二氧磷杂环戊烷硫代磷酸酯1及2-邻苯二甲酰亚氨基乙醇环甘油硫代磷脂缀合物2为模型,研究开环反应的条件.结果表明,在室温下,甲醇对化合物1中1,3,2-二氧磷杂环戊烷中的磷原子的亲核进攻,生成O-甲基-O-羟乙基-O-(2-邻苯二甲酰亚氨基)乙基硫代磷酸酯3,但是在此条件下,甲醇与化合物2不反应.在室温下,以异丙醇作溶剂,苯硒酚与化合物2不反应.在氢氧化钾存在下,以异丙醇/水作溶剂(体积比20∶1),在室温下,硒酚可以有效地进攻中化合物2中1,3,2-二氧磷杂环戊烷中的碳原子生成相应的开环产物.按照这一反应条件,顺利实现了硒酚对N1-(2-呋喃基)-N3-羟烷基-5-氟脲嘧啶硫代环甘油磷脂缀合物的亲核开环,生成甘油骨架的端碳原子上带有芳硒基新颖的磷脂核苷缀合物.对开环反应的机理进行了探讨.体外细胞毒性试验结果表明:产物对膀胱癌细胞T-24、胃癌细胞BGC-823的恶性增殖抑制效果优于替加氟;但对正常肝上皮细胞毒性也大于替加氟.

 
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