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电生理心脏模型
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  “电生理心脏模型”译为未确定词的双语例句
     Most previous electrical heart models were static,not beating ones.
     以往的电生理心脏模型大多是静态的,而非动态模型。
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  相似匹配句对
     Simulation Application of Whole-heart Electrophysiological Model
     全心脏生理模型的仿真应用
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     Effects of pethidine on cardiac electrophysiological properties
     哌替啶的心脏生理效应
短句来源
     Virtual Heart-Computer Simulation of Electrocardiological Activity
     心脏活动的计算机仿真模型
短句来源
     Three-dimensional Motion Analysis of Right Ventricular Based on an Electrophysiologic-mechanical Composite Heart Model
     基于生理-力学复合心脏模型的右心室三维运动分析
短句来源
     Computer Simulation Methods of Cardiac Electrophysiology
     心脏生理的计算机仿真方法研究
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The human heart pumps blood via contraction of myocardial muscleand the mechanical properties of the muscle depend highly on its fibrous structure. Considering the fiber orientation, a three-dimensional finite element mechanical model of left ventricle is constructed, based on composite theory and an electric model of human heart. The mechanical response of the left ventricle subjected to the active force is simulated. The simulation results show that the left ventricle contraction is very complicated, it includes...

The human heart pumps blood via contraction of myocardial muscleand the mechanical properties of the muscle depend highly on its fibrous structure. Considering the fiber orientation, a three-dimensional finite element mechanical model of left ventricle is constructed, based on composite theory and an electric model of human heart. The mechanical response of the left ventricle subjected to the active force is simulated. The simulation results show that the left ventricle contraction is very complicated, it includes axial shortening, radial contraction, basal contraction and twisting around the long axis at different degree, and among these deformations, the apical contraction is the strongest. In addition, the stress distribution on the left ventricle wall is not uniform, and it reduces from the endocardium to the epicardium. The stress on the apex and base of left ventricle is much greater, and the greatest exists on the apex of endocardium. These results show that the cardiomechanics is sensitive to the myocardial fibrous structure, the left ventricle geometric shape and electric active stimulus. The simulation results are compared with the solutions obtained from corresponding medical images and those comes from other models,it proves that the given model can be used to study the mechanical function of the left ventricle.

人体心脏通过电兴奋引起的心肌收缩实现泵血功能 ,而心肌的力学特性高度依赖于肌纤维结构。本文根据肌纤维旋向和复合材料理论以及电生理心脏模型建立了左心室的有限元机械模型 ,仿真研究了左心室在心电兴奋力作用下的力学响应。结果表明左心室的收缩过程是十分复杂的 ,包括轴向和径向的收缩及绕长轴的不同程度的旋转扭曲。从总体趋势上看 ,心尖处变形最为严重。此外 ,仿真结果还表明 ,心壁应力分布不均匀 ,从内壁到外壁有所减少 ;在心尖和心底部应力较大 ,其中内壁心尖处应力最大。这些结果说明了心脏的力学特性与心肌纤维结构、左心室的几何形状以及电兴奋刺激密切相关。作者将本文的仿真结果与医学图像及其它模型进行了对比分析 ,结果表明了该模型用于分析心肌力学功能特性的可行性

Most previous electrical heart models were static,not beating ones.When computing body surface ECG based on quasi-static field theory,the distances between equivalent cardiac dipoles(source points) and body surface(field points) were supposed to be constant during the whole cardiac cycle.Large system errors could be introduced because of the significant relative position changes of source-field points during cardiac systole and diastole.Therefore,to improve the ECG simulation accuracy,a beating or dynamic heart...

Most previous electrical heart models were static,not beating ones.When computing body surface ECG based on quasi-static field theory,the distances between equivalent cardiac dipoles(source points) and body surface(field points) were supposed to be constant during the whole cardiac cycle.Large system errors could be introduced because of the significant relative position changes of source-field points during cardiac systole and diastole.Therefore,to improve the ECG simulation accuracy,a beating or dynamic heart model should be considered.In this investigation,a dynamic or beating heart model was constructed based on our previous static electrical heart model,and a comparative simulation study of 12-lead ECG based on dynamic and static heart models was presented.In the dynamic heart model,the coupling of electrical excitation and mechanical contraction were considered,and the resulted relative position changes between heart wall and body surface during cardiac systole and diastole were employed to calculate body surface ECG afterwards.The results showed that,compared with ECG signals simulated from the static electrical heart model,the ECG signals obtained from the beating heart model was more accordant with clinical recorded ECG,especially for ST segment and T wave of V1-V6 lead ECG.For slight-degree myocardial ischemia,the ST segment and T wave changes were observed from the simulated ECG based on beating heart model,while the ST segment and T wave of simulated ECG based on static heart model was almost unchanged compared with normal ECG.These simulation results suggest that the beating heart model generate more accurate ECG signals.

以往的电生理心脏模型大多是静态的,而非动态模型。这样在用准静电场理论求解体表电位时,整个心动周期中等效心电偶极子(源点)与体表(场点)之间的距离假设为恒定不变,从而会引入较大的系统误差。因此,为了更准确仿真心电图,有必要采用动态或跳动的心脏模型。基于原来静态心脏模型,构造了一个动态心脏模型,并对体表12导联心电图进行仿真比较研究。在动态心脏模型中考虑了心肌电兴奋引起的心脏机械力学收缩,通过计算心动周期中心室壁的位移,从而将心脏与体表之间的相对距离变化考虑进体表电位计算过程。仿真结果表明,对于正常心电图,基于动态心脏模型的仿真结果比基于静态心脏模型的仿真结果更符合临床记录心电图,特别是V1-V6胸导联的ST段和T波。对于前壁轻微缺血情况,在动态心脏模型的仿真心电图中能明显看出ST段和T波的变化,而在静态心脏模型的仿真心电图中与正常心电图相比看不出什么变化。本研究的仿真研究证实了动态心脏模型的确能更准确地仿真体表心电图。

Based on our previous electrical heart model,an electromechanical biventricular model was constructed by means of composite material theory and the finite element method.And the 3-D motion of the right ventricular wall was simulated based on this model.The orientation of cardiac fibers and myocardial contractility were taken into consideration during simulation modeling.The propagation of electrical excitation was simulated using an electrical heart model,and the resulting active forces was used to calculate...

Based on our previous electrical heart model,an electromechanical biventricular model was constructed by means of composite material theory and the finite element method.And the 3-D motion of the right ventricular wall was simulated based on this model.The orientation of cardiac fibers and myocardial contractility were taken into consideration during simulation modeling.The propagation of electrical excitation was simulated using an electrical heart model,and the resulting active forces was used to calculate the ventricular wall motion.Regional deformation and Lagrangian strain tensors were calculated during systole.Displacements,minimum principal strains were used to describe the motion of the right ventricle.The simulation results are in good accordance with results obtained from MR tagging images reported in literatures.In addition,the results also show that although the maximum displacement occurs in the base of the heart,however,the maximum contraction occurs in the apex of the heart.Such result is very difficult to be obtained by means of animal experiment or human experiment.This study suggests that such electrophysiologic-mechanical biventricular models have the important significance to be used to assess the mechanical functions of the two ventricles.

在原有电生理心脏模型基础上,我们采用有限元方法和复合材料理论建立了一个电生理-力学复合双心室模型,并基于该模型对右心室心壁在收缩期的三维运动进行仿真分析。模型建立过程中,考虑了心肌的纤维旋向、心电兴奋产生的心肌收缩力。心室壁位移、最小主应变(E 3)等用来表征心室的运动。仿真结果与加标记磁共振成像的实验结果基本一致。另外,仿真结果还表明,虽然心基部位移最大,但最大收缩力却发生在心尖部,这个结果用一般的动物实验或人体实验是难以得到的。因此,电生理-力学复合双心室模型对于今后进一步评价心脏功能具有重要意义。

 
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