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  hepatitis b
This study evaluates the survival outcomes of patients who underwent living-donor liver transplantation (LDLT) using right lobe liver grafts for fulminant liver failure due to hepatitis B infection.
      
Expression and Characterization of Hepatitis B Surface Antigen in Transgenic Potato Plants
      
Transgenic potato plants expressing the gene of hepatitis B surface antigen (HBsAg) under the control of the double promoter of 35S RNA of cauliflower mosaic virus (CaMV 35SS) and the promoter of patatin gene of potato tubers have been obtained.
      
The molecular weight of HBsAg peptide was approximately 24 kD, which is in agreement with the size of the major protein of the envelope of hepatitis B virus.
      
Therefore, as well as in recombinant HBsAg-yeast cells, assembling of HBsAg monomers into immunogenic aggregates takes place in HBsAg-transgenic potato, which can be used as a source of recombinant vaccine against hepatitis B virus.
      
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  type hepatitis
A possibility that this escape mutant had selective advantage over wild-type hepatitis B virus under immune pressure is discussed.
      
Hepatitis B virus is a small hepatotropic DNA virus, causing acute and chronic B-type hepatitis in man.
      
In 1992 he developed a very severe disease which was diagnosed as severe type hepatitis B.
      
Nucleotide sequence of wild-type hepatitis A virus GBM in comparison with two cell culture-adapted variants.
      
No animal model or cell culture system is available for the isolation or propagation of noroviruses and most wild-type hepatitis A virus strains.
      
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One hundred seventy-four cases (5.82%) with elevated SGPT (48-415u), including 14 HBsAg positive cases, in 2,973 pregnant women during 1980-1982 were reviewed. Among the 174 cases, 2 were associated with active hepatitis, 26 were of cholestasis, 41 of hepatic damage due to hypertensive disorders of pregnancy, 13 healthy HBsAg carrier with pregnancy hepatopathy, and 92 of pregnancy hepatopathy. The incidences of dystocia and puerperal complications were almost the same in the groups of pregnant women with or...

One hundred seventy-four cases (5.82%) with elevated SGPT (48-415u), including 14 HBsAg positive cases, in 2,973 pregnant women during 1980-1982 were reviewed. Among the 174 cases, 2 were associated with active hepatitis, 26 were of cholestasis, 41 of hepatic damage due to hypertensive disorders of pregnancy, 13 healthy HBsAg carrier with pregnancy hepatopathy, and 92 of pregnancy hepatopathy. The incidences of dystocia and puerperal complications were almost the same in the groups of pregnant women with or without elevated SGPT levels. One hundred forty-eight out of 162 postpartum women had SGPT returned to normal 4-14 days after delivery.

本文报道1980~1982年产前检查2,973例,孕妇SGPT升高者174例,占5.82%。其中伴有HBsAg阳性者14例,SGPT值48~415u。174例中诊断妊娠合并肝炎2例,胆汁郁积症26例,妊娠高血压综合征肝损害41例,乙型肝炎抗原携带者并发妊娠肝损13例,单纯妊娠肝损92例。难产率及并发症与同期SGPT正常产妇相比无差异。除2例肝炎外,余均未经治疗,随访162例,产后4~14天内SGPT恢复正常者148例,占91.34%。本文对孕晚期SGPT升高、妊娠胆汁郁积症、妊娠高血压综合征肝损害、乙型肝炎抗原携带者妊娠肝损害等进行了探讨。

Twenty-four neonates born to HBsAg carrier mothers were tested by ELISA, RIA and dot blot hybridization for the presence of HBV markers in the cord blood. Placental tissue samples from 24 HBsAg carrier mothers were detected for HBV-DNA by dot blot hybridization using 32P-labelled cloned HBV-DNA as a probe. The results showed that antiHBc-IgM were found in the cord blood of 5 infants born to 5 HBsAg carrier mothers who were negative for antiHBc-IgM. HBV-DNA was found in one liver tissue sample from an aborted...

Twenty-four neonates born to HBsAg carrier mothers were tested by ELISA, RIA and dot blot hybridization for the presence of HBV markers in the cord blood. Placental tissue samples from 24 HBsAg carrier mothers were detected for HBV-DNA by dot blot hybridization using 32P-labelled cloned HBV-DNA as a probe. The results showed that antiHBc-IgM were found in the cord blood of 5 infants born to 5 HBsAg carrier mothers who were negative for antiHBc-IgM. HBV-DNA was found in one liver tissue sample from an aborted fetus of a HBsAg carrier mother. Thus, 6 neonates were infected in uteri among 24 neonates (6/24,25%).23 placental tissue samples were found to be HBV-DNA positive among 24 placental samples from HBsAg carrier mothers, indicating that placental tissue could be infected by HBV. All 6 mothers of intranterine infected infants had no history of threatened abortion and / or threatened premature labor. Placental leakage is not the only route of intrauterine infection.

本文对乙型肝炎病毒宫内感染的发生率及机理进行了研究。24例HBsAg阳性母亲的新生儿中,5例脐血AntiHBc-IgM阳性,1例引产儿肝组织HBV-DNA阳性(斑点杂交法)。宫内感染率为6/24(25.0%)6例母亲全无先兆流产及/或先兆早产病史。斑点杂交法检测24例HBsAg阳性母亲胎盘组织HBV-DNA,阳性23例。实验结果表明宫内感染发生率较高。胎盘组织可受HBV感染。母血漏入并非宫内感染的唯一途径。

This paper analyses 500 eases of pregnant women with HNANB (E) who were admitted to the hospital of Meyu County in s uth Xinjiang during the breakout of HNANB (E) from December 1986 to April 1988. HNANB (E) was found to occur greatly in pregnant women within the age of 19-39 years old(87.2%), and mostly in the second and third trimesters. 24.8% of all cases developed into fulminant hepatitis. The fatality rate was higher(20.8%)in pregnant women with HNANB (E) . Labor can severely influnce the prognosis and result...

This paper analyses 500 eases of pregnant women with HNANB (E) who were admitted to the hospital of Meyu County in s uth Xinjiang during the breakout of HNANB (E) from December 1986 to April 1988. HNANB (E) was found to occur greatly in pregnant women within the age of 19-39 years old(87.2%), and mostly in the second and third trimesters. 24.8% of all cases developed into fulminant hepatitis. The fatality rate was higher(20.8%)in pregnant women with HNANB (E) . Labor can severely influnce the prognosis and result in post-partum hemorrhage which warsened the hepatitis. Pregnant women infected with HNANB (E) led to miscarriages, prematurs and stillbirths. The HNANB (E) virus may infect the fetus through the placenta.

本文对1986年12月~1988年4月,在新疆墨玉县爆发流行肠传非甲非乙型肝炎[HNANB(E)]期间,收住该县医院的500例妊娠合并肠传非甲非乙型肝炎患者进行了分析。其中19~39岁患者占87.2%,以中,晚期妊娠为主。24.8%(124例)为重症肝炎。病死率达20.8%。分娩对预后有严重影响,易导致产后大出血,加重原有肝病。HNANB(E)对妊娠和胎儿影响较大,早产和死产率较高,有胎儿宫内感染的可能。

 
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