人源单克隆抗体 human monoclonal antibody(2) human anti-hbs fab(0) human monoclonal antibodies(2)   human monoclonal antibody      Human monoclonal antibody Fab fragments to HIV 1 have been prepared by using phage display technology.      应用噬菌体抗体库技术有效地筛选出了多株抗HIV 1人源单克隆抗体。 短句来源      Objective: To prepare and purify human monoclonal antibody fragments from a combinatorial library to hepatitis B virus surface antigens with a self prepared affinity chromatography column.      目的：探索亲和纯化人源单克隆抗体片段的简便实用方法。 方法：应用自制的抗人免疫球蛋白片段抗体（Anti－Fab）与链球菌蛋白G亲和胶（Gam m a Bind）交联制备亲和层析柱，用一步法从工程菌培养上清中纯化人源抗HBs单克隆Fab 片段。 短句来源   human monoclonal antibodies      High affinity anti-TNFα human monoclonal antibodies directly selected from pooled phage display library      从混合的噬菌体抗体库中直接筛选高亲和性的抗肿瘤坏死因子-α人源单克隆抗体 短句来源      Human monoclonal antibodies can be made by means of antibody library technology.      利用抗体库技术可制备人源单克隆抗体。 短句来源   “人源单克隆抗体”译为未确定词的双语例句      Traditional murine antibodies were limited by human anti-mouse antibody (HAMA) response, and humanized antibodies pave the way to solve this problem.      由于人体对鼠源单克隆抗体能产生人抗鼠抗体反应(HAMA)，人源单克隆抗体成为单克隆抗体应用于临床治疗的一个关键因素。 短句来源      The toxin neutralizing activity was detected by human MAbs G2、G6、G2+G6 and horse anti tetanus antitoxin.      对抗破伤风毒素人源单克隆抗体G2、G6、G2 +G6与精制破伤风抗毒素进行了中和效力比较试验。 短句来源      Study of protective ability of anti tetanus humans monoclonal antibodies with neutralizing activity      抗破伤风毒素人源单克隆抗体中和效力的研究 短句来源      This study aims to construct a human immunoglobulin combinatorial library by using phage surface display expression system and to screen the autoantibodies against platelet, preparing for the further screening of antibodies directed against the GPⅡb/Ⅲa which have been regarded as potential agents to diagnose or treat acute coronary syndromes.      该技术已广泛用于制备人源单克隆抗体及免疫学研究中。 本研究旨在运用噬菌体抗体库技术构建一个经血小板自身免疫的抗体组合文库,为下步筛选针对血小板特异性靶点如GPⅡb/Ⅲa等的人源抗体,进行以GPⅡb/Ⅲa受体等作为靶点的治疗性人源抗体的研究和开发奠定基础。 短句来源      Human anti-TNFα monoclonal antibodies were directly selected from the pooled human antibody combinatorial libraries using phage display technology. Three different assays proved that phage antibodies that could bind TNFα were enriched effectively after five rounds of biopan- ning.      采用噬菌体抗体库技术，从未经免疫的混合人噬菌体抗体库直接筛选抗TNFα的人源单克隆抗体，3种不同的检测手段表明，经过5轮的筛选，能够与TNFα结合的噬菌体抗体得到了有效的富集。 短句来源 更多          相似匹配句对      Humanization of murine monoclonal antibody      鼠单克隆抗体人源化 短句来源      GENERATION OF HUMAN MONOCLONAL ANTIBODY LIBRARY TO HEPATITIS B SURFACE ANTIGEN      人源抗HBsAg单克隆抗体组合文库的建立 短句来源      Establishment of Monoclonal Antibodies to E.Coli HEAT-Labile En-teratoxin of Human      人源大肠杆菌不耐热肠毒素单克隆抗体的研究 短句来源      Epratuzumab is a humanized anti-CD22 monoclonal antibody.      epratuzumab是抗CD22的人源化单克隆抗体。 短句来源      Study of protective ability of anti tetanus humans monoclonal antibodies with neutralizing activity      抗破伤风毒素人源单克隆抗体中和效力的研究 短句来源 查询“人源单克隆抗体”译词为用户自定义的双语例句     我想查看译文中含有：的双语例句 为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法，我们为您准备了出自英文原文的大量英语例句，供您参考。   human monoclonal antibody Additional studies have demonstrated that the pANCA human monoclonal antibody (mAb) Fab 5-3 reacts with histone H1 and with bacterial and mycobacterial antigens. 例句来源       Rituximab is a chimeric mouse-human monoclonal antibody against the B cell-specific antigen CD20, which selectively and profoundly depletes B lymphocytes and has been widely used to treat B cell lymphomas. 例句来源       4C10 was made against the human monoclonal antibody (HuMAb) L612, which reacts with several types of human cancer cells, including melanoma and breast cancer. 例句来源       Serodiagnosis of cancer, using porcine antigens recognized by human monoclonal antibody, HB4C5 例句来源       Antigens, recognized by human monoclonal antibody (HB4C5) generated from a lung cancer patient, were found to occur in porcine pancreas. 例句来源       更多             human monoclonal antibodies The VH3 gene family, which encodes for approx 50% of immunoglobulins expressed by peripheral B-cells from normal adults, is underrepresented in human monoclonal antibodies to HIV-1 and in the peripheral B-cells of AIDS patients. 例句来源       To produce human monoclonal antibodies in bacteria, a gene repertoire of IgM variable regions was isolated from human peripheral B lymphocytes by the polymerase chain reaction. 例句来源       In this review we focus on advances in the generation of both genetically engineered humanized and fully human monoclonal antibodies. 例句来源       The double replacement of Asn247Ser and Leu574Pro in glutamic acid decarboxylase 65 resulted in the loss of binding of all eleven human monoclonal antibodies, irrespective of their epitope recognition. 例句来源       Replacement of Asn247Ser did not, however, influence the binding of any patients serum or human monoclonal antibodies.?Conclusion/interpretation. 例句来源       更多                    To identify the humoral immunological characteristics of the super severe combined immunodeficient mice (B. C. B-17 scid-beige mice) ,sera of the mice were analysed with various immunochemical techniques. None of the techniques (immuno-diffusion assay, SDS-PAGE and densitoscanning, western-blotting) could demonstrate the presence of immunoglobulin. This super severe combined immunodeficient strain of mice will be useful to the construction of the human-immunodef icient mice model and the production of human...             本文采用多项免疫化学技术对超重症联合免疫缺陷小鼠(B.C,B-17 scid-beige)血清免疫化学特征进行了分析。结果表明: 用免疫双扩散试验、SDS-PAGE和薄层凝胶扫描、以及免疫印迹法均未测出有免疫球蛋白存在,从而表明该品系小鼠血清免疫球蛋白缺失,该鼠体内已导入scid基因。该特征在人源单克隆抗体及其它蛋白质基因工程产品的生产等方面具有重要意义。 文摘来源          Con the methods of antigen based selections,one human monoclonal antibody fragment library to hepatitis B surface antigeus(HBsAg)was generated. Liquid HBsAg were coated on the ELISA plate and one combinatorial antibody library that was from a HBsAg-positive donor was panned with the HBsAg coated wells,The antigen specific phages in the library were selected and enriched to form a HBsAg-specific library,Choosing 12 clones for Fab expression and anti-HBsAg specificity study,Fab supernatants from 5 clones show...             应用固相抗原筛选法，建立了人抗ＨＢｓＡｇ单克隆抗体组合文库。以液相ＨＢｓＡｇ包被酶标板，对抗ＨＢｓＡｇ血清阳性供者文库经多次筛选、扩增，建立起针对ＨＢｓＡｇ的组合抗体子文库。选取１２个克隆进行抗体片段表达研究，并对该抗体进行特异性酶联免疫测定，其中５株为抗－ＨＢｓ阳性，应用组合文库制备人源单克隆抗体是─种简便、实用的方法。 文摘来源          Phage antibody library is a repertoire of antibodies, which connects human antibody genes to phagemid vector and is expressed in bacteria. Human monoclonal antibodies can be made by means of antibody library technology. This is an important new technology in biotechnological field recently. This article will review its production, development and prospects.             噬菌体抗体库（ｐｈａｇｅａｎｔｉｂｏｄｙｌｉｂｒａｒｙ）是将人抗体基因与噬菌粒载体相连，在细菌体内表达而制备的人全套抗体（ｒｅｐｅｒｔｏｉｒｅｏｆａｎｔｉｂｏｄｉｅｓ）。利用抗体库技术可制备人源单克隆抗体。这是目前生物技术领域中一项重要的新技术。该文综述了其产生、发展和前景。 文摘来源   << 更多相关文摘         相关查询: 人源 人源轮状病毒 人源fab 人源抗体 人源大肠杆菌 人源输入 人源烃 人源性 人源株 人源胰岛素原 人源组织 人源抗体酶  对查询结果不满意

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