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聚乙烯醇水凝胶弹性体
相关语句
  polyvinyl alcohol hydrogel elastomers
     A study on repair of the defects of articular cartilage with polyvinyl alcohol hydrogel elastomers composite device
     聚乙烯醇水凝胶弹性体复合物修复关节软骨缺损的实验研究
短句来源
     Development of Artificial Disc Nucleus Materials (Semicrystalline Polyvinyl Alcohol Hydrogel Elastomers)
     人工髓核材料(半晶聚乙烯醇水凝胶弹性体)的研制
短句来源
     Objective:To investigate the use of polyvinyl alcohol hydrogel elastomers composite device as the substitute of articular cartilage to repair the defects in dogs.
     目的:研究应用聚乙烯醇水凝胶弹性体复合物作为关节软骨替代物修复成年犬的关节软骨缺损。
短句来源
  相似匹配句对
     HIGH WATER CONTENT POLY (VINYL ALCOHOL) ELASTOMER
     高含水聚乙烯醇弹性体
短句来源
     Development of Artificial Disc Nucleus Materials (Semicrystalline Polyvinyl Alcohol Hydrogel Elastomers)
     人工髓核材料(半晶聚乙烯醇水凝胶弹性体)的研制
短句来源
     A study on repair of the defects of articular cartilage with polyvinyl alcohol hydrogel elastomers composite device
     聚乙烯醇水凝胶弹性体复合物修复关节软骨缺损的实验研究
短句来源
     Survey on Study of Poly(Vinyl Alcohol) Hydrogels
     聚乙烯醇(PVA)水凝胶研究进展
短句来源
     STUDY OF REINFORCEMENT OF POLY (VINYL ALCOHOL) HYDROGEL FILM
     聚乙烯醇水凝胶膜的强化研究
短句来源
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For the purpose of developing of disc nucleus replacement (semicrystalline PVA hydrogel elastomers) and explorating the possibility of clinical application, in this study,the aqueous PVA solution froze at -20℃ for 6-12 h, and then thawed at room temperature for 1-2h. The same process was repeated 1-3 times. After the specimen was dehydrated in vacuum, a kind of artificial disc nucleus materials (semicrystalline PVA hydrogel elastomers ) was formed. DSC and mechanical tests were conducted to investigate the...

For the purpose of developing of disc nucleus replacement (semicrystalline PVA hydrogel elastomers) and explorating the possibility of clinical application, in this study,the aqueous PVA solution froze at -20℃ for 6-12 h, and then thawed at room temperature for 1-2h. The same process was repeated 1-3 times. After the specimen was dehydrated in vacuum, a kind of artificial disc nucleus materials (semicrystalline PVA hydrogel elastomers ) was formed. DSC and mechanical tests were conducted to investigate the influence of aqueous PVA solution concentration, of dehydrating in vacuum, and of γ-ray irradiating upon the degree of crystallity and mechanical properties of PVA hydrogel elastomers.

研制一种可替代椎间盘髓核并恢复其功能的生物医用材料 ,探讨半晶聚乙烯醇水凝胶弹性体材料临床应用的可行性。聚乙烯醇 (PVA)水溶液在 - 2 0℃下冷冻 6~ 12 h,室温下融化 1~ 2 h,上述过程重复 1~ 3次 ,然后对试样进行真空脱水 ,制得人工髓核材料 (半晶 PVA水凝胶弹性体 )。差示扫描量热法 (DSC)和力学性能试验研究了 PVA水溶液浓度、真空脱水和 γ射线辐照对水凝胶 PVA的结晶度和力学性能的影响

Objective:To investigate the use of polyvinyl alcohol hydrogel elastomers composite device as the substitute of articular cartilage to repair the defects in dogs.Method:Eight mature adult mongrel dogs were randomly divided into two groups. Both hind legs of each dog were operated to make defects of cartilage in the load-bearing portions of the medial femoral condyles. The polyvinyl alcohol hydrogel elastomers composite device was implanted in the defects afterward. Four dogs were sacrificed in 8 weeks and others...

Objective:To investigate the use of polyvinyl alcohol hydrogel elastomers composite device as the substitute of articular cartilage to repair the defects in dogs.Method:Eight mature adult mongrel dogs were randomly divided into two groups. Both hind legs of each dog were operated to make defects of cartilage in the load-bearing portions of the medial femoral condyles. The polyvinyl alcohol hydrogel elastomers composite device was implanted in the defects afterward. Four dogs were sacrificed in 8 weeks and others were killed in 24 weeks postoperatively. The cartilage around the implant, the subchondral bone, the menisci and the tibial joint surface were observed with light microscopes.Result:The range of motion of each animal′s knee joint was almost normal after operation. All of the implants attached firmly to the underlying bone through bone ingrowth into the pores of the titanium fiber mesh after 8 and 24 weeks. There were not any lymphocyte infiltration around the implants and no cartilage degeneration. Conclusion: The polyvinyl alcohol hydrogel elastomers have good lubrication properties, adequate shock-absorbing ability, high wear resistance and good biocompatibility, which is similar to the properties of the articular cartilage. The composite device became firmly attachedy to the host bone as a result of bone penetration through the pores of the titanium fiber mesh substrate. It could be used as artificial articular cartilage to repair the defects of cartilage.Author′s address Department of Orthopaedics, the Third Hospital, Peking University,Beijing,100083

目的:研究应用聚乙烯醇水凝胶弹性体复合物作为关节软骨替代物修复成年犬的关节软骨缺损。方法:取8只成年犬随机均分为A、B两组,每组4只。在犬双后肢膝关节股骨内髁负重面制造软骨缺损区,在缺损区植入同等大小的聚乙烯醇水凝胶弹性体复合物。手术后8周和24周分别将A、B两组实验动物处死取材。在肉眼和光镜下观察植入物周围的软骨和软骨下骨,对应的半月板和胫骨面的软骨组织。结果:大体观察,实验动物术后关节功能良好,植入物在8周和24周均未见松动和脱落,与软骨下骨牢固结合。植入物周围软骨和对应部位的半月板和胫骨面软骨未见退变表现。光镜下观察8周和24周植入物周围未见软骨组织退变表现;软骨下骨组织长入钛纤维网孔隙中,形成生物力学固定;植入物周围无淋巴细胞浸润。结论:聚乙烯醇水凝胶弹性体具有与关节软骨类似的物理特性和良好的生物相容性,能作为关节软骨替代物修复关节软骨的缺损,恢复关节面的完整,维持关节功能。

 
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