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大鼠原位肾移植     
相关语句
  orthotopic renal transplantation in rats
     Improved techniques and observation of acute allograft rejection of orthotopic renal transplantation in rats
     大鼠原位肾移植技术的改进及急性排斥反应观察
短句来源
     Experiment 1AIM: To study and modify the techniques of orthotopic renal transplantation in rats, and to observe the acute allograft rejection of renal transplantation in recepted Wistar rats.
     目的:对大鼠原位肾移植模型进行技术改进,并观察异基因肾移植大鼠急性排斥发生的规律。
短句来源
     AIM: To modify the techniques of orthotopic renal transplantation in rats and to observe the acute allograft rejection of renal transplantation in Wistar rats.
     目的:对大鼠原位肾移植模型进行技术改进,并观察异基因肾移植大鼠急性排斥发生的规律.
短句来源
  rat renal heterotopic transplantation
     The rat renal heterotopic transplantation model (n=32) was established.
     建立异基因大鼠原位肾移植模型。
短句来源
  “大鼠原位肾移植”译为未确定词的双语例句
     Establishment of a Rat Model of Orthotopic Renal Transplantation by Harvesting Two Kidneys from One Donor
     双侧供肾大鼠原位肾移植模型的建立
短句来源
     Methods:The erythrocyte C3b receptor rate (C3bRR), immune complex rate (ICR), immune adherence enhance factor(RFER) and immune adherence inhibitor factor (RFIR) were determined in 20 renal transplanted rats with acute rejection and in 20 healthy rats.
     方法 通过建立大鼠原位肾移植模型 ,测定 2 0只术后急排期大鼠的红细胞C3b受体花环率 (C3bRR) ,免疫复合物花环率 (ICR) ,免疫黏附促进因子 (RFER) ,免疫黏附抑制因子 (RFIR)及血清SOD酶活性、MDA浓度。
短句来源
     Methods The erythrocyte C3b receptor rate(C3bRR),immune complex rate(ICR),immune adherence enhance factor(RFER) and immune adherence inhibitor factor(RFIR) were determined in 20 renal transplanted rats with acute rejection and in 20 healthy rats.
     方法 建立大鼠原位肾移植模型 ,测定 2 0只术后急排期大鼠的红细胞C3b受体花环率 (C3bRR) ,免疫复合物花环率(ICR) ,免黏附促进因子 (RFER) ,免疫黏附抑制因子 (RFIR)及血清SOD酶活性、MDA浓度。
短句来源
     Establishment of a Modified Orthotopic Renal Transplantation Model in Rat
     一种新的大鼠原位肾移植模型的建立
短句来源
     Improved in situ kidney transplantation in rats
     改良的大鼠原位肾移植模型的建立
短句来源
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  相似匹配句对
     Technique of Orthotopic Allograft Kidney Transplantation in Rats
     大鼠同种异体原位移植
短句来源
     Experience in building a rat model of kidney transplantation
     大鼠原位移植模型建立的手术技巧
短句来源
     The Rat Model of the Renal Allograft in Prime Position
     大鼠原位异体移植的模型研究
短句来源
     Improved in situ kidney transplantation in rats
     改良的大鼠原位移植模型的建立
短句来源
     Prevention and cure of complications in the renal orthotopic transplantation of rat
     大鼠原位移植并发症的防治研究
短句来源
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The Purpose of this study was to address the mechanism of medicine S which has anti rejection effects of renal allografts in rats. Kidney transplantations were performed from SD to Wistar strain (allogeneic) and from Wistar to Wistar (Isograft) using the same modified technigue described by Fabre and kamada. Experimental rats were divided into five groups. Group Ⅰ (Isograft group) and group Ⅱ (allograft group)as controls were not treated with medicine. The others were allograft groups which received medicine...

The Purpose of this study was to address the mechanism of medicine S which has anti rejection effects of renal allografts in rats. Kidney transplantations were performed from SD to Wistar strain (allogeneic) and from Wistar to Wistar (Isograft) using the same modified technigue described by Fabre and kamada. Experimental rats were divided into five groups. Group Ⅰ (Isograft group) and group Ⅱ (allograft group)as controls were not treated with medicine. The others were allograft groups which received medicine S, Cyclosporine A, and low dose Cyclosporine combined with medicine S, respectively. Renal function and resultant morphology changes were assessed 2, 4 weeks after transplantation. All sections of kidney grafts were stained with monoclonal antibody class Ⅱ MHC (OX6), and then the surface densities of positive staining were quantified by computer image analysis. The level of molecular expression in group Ⅱ was significantly increased (7.61±0.57 vs 0.51±0.2 of group Ⅰ, P<0.01) . In groups Ⅰ and Ⅳ, the molecule of expression was reduced, compared with the groups Ⅱ, Ⅲ and Ⅴ ( P<0.05 ). The results suggest that medicine S decreases the level of class Ⅱ MHC expression and medicines combined with lowe dose cyclosporine is more effective than cyclosporine alone.

为探索草药S抗大鼠同种异体肾移植急性排斥的作用机理,采用改进的Fabre和Ka-mada大鼠原位肾移植模型,将SD大鼠肾移植给Wistar大鼠为同种异体移植,Wistar移植给Wistar大鼠为同品系移植(空白对照),共设五个实验组,观察移植后受体鼠存活、检测移植肾功能及定量测定移植肾内MHCClasⅡ抗原分子的表达。结果表明,草药S能延长受体鼠存活时间,并抑制MHCClasⅡ在移植肾内的表达(与不用药物组比较P<0.01),S药加小剂量环孢素A(cyclosporineA,CsA)治疗组与同系组相比差异无显著性(P>0.05)。这些结果提示,移植肾内MHCClassⅡ表达水平的高低与其排斥的强弱有相关性。

bjective To assess relationship between the renal graft expression of ICAM1 (intercellular adhesion molecule1) and LFA1 (Lymphocyte function associated antigen1) molecule and the graft rejection. Methods Rat kidney transplantation was performed according to the procedure of kamada, with some modification. Experimental rats were divided into 5 groups. The survival time of recipient rats and function of grafts after renal transplantation were observed. The sections of renal graft were stained for monoclonal...

bjective To assess relationship between the renal graft expression of ICAM1 (intercellular adhesion molecule1) and LFA1 (Lymphocyte function associated antigen1) molecule and the graft rejection. Methods Rat kidney transplantation was performed according to the procedure of kamada, with some modification. Experimental rats were divided into 5 groups. The survival time of recipient rats and function of grafts after renal transplantation were observed. The sections of renal graft were stained for monoclonal antibody ICAM1 and LFA1, and then quantification of ICAM1 and LFA1 expression was accomplished by computer image analysis. Results ICAM1 and LFA1 increased significantly in the renal allograft rejection group as compared with the nonrejection group (P<0.05). Conclusion Both the biopsy of renal graft and the monitoring of ICAM1 and LFA1 are useful tools in diagnosing and treating acute rejection.

目的探讨移植肾组织内细胞间粘附分子-1(ICAM-1)/淋巴细胞功能相关抗原-1(LFA-1)的异常表达与移植排斥的关系。方法采用改进的大鼠原位肾移植模型,分五个实验组,在不同的时间段、观测受体鼠存活、肾功能;以及移植肾组织用单克隆抗体免疫组织化学染色后,图象分析法定量测定移植肾组织ICAM-1/LFA-1分子表达的水平。结果移植肾急性排斥组ICAM-1/LFA-1分子水平显著高于同品系移植对照组和药物治疗组。结论移植肾组织活检同时检测组织内ICAM-1/LFA-1分子的表达,在肾移植急性排斥的诊断和治疗方面具有极其重要的临床意义。

Objective To find the ways of preventing the complications during establishing animal model of the renal orthotopic transplantation in rat. Methods We performed 69 rat renal transplantation with end side anastomosis of the left renal artery and ureter, end end sleevelet anastomosis of the left renal vein. We analysed these causes of the death rats. Results Sixty one rats lived and 8 rats died from complications. Conclusion Preparation of pre operation, operations and attendance of post operation affect...

Objective To find the ways of preventing the complications during establishing animal model of the renal orthotopic transplantation in rat. Methods We performed 69 rat renal transplantation with end side anastomosis of the left renal artery and ureter, end end sleevelet anastomosis of the left renal vein. We analysed these causes of the death rats. Results Sixty one rats lived and 8 rats died from complications. Conclusion Preparation of pre operation, operations and attendance of post operation affect the establishment of rat renal transplantation. We can decrease the mortality by the concrete methods.

目的 找到预防大鼠原位肾移植模型建立过程中发生并发症的方法。方法 采用动脉端 侧吻合、静脉袖套吻合、输尿管端 侧吻合的方法进行 6 9次大鼠原位肾移植实验 ,并分析死亡的原因。结果 共有 6 1只大鼠存活 ,8只大鼠死于并发症。结论 大鼠肾移植手术的术前准备、术中操作及术后护理对模型的建立有重要影响 ,采取具体的保护措施可以减少大鼠的死亡率

 
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