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肛管鳞癌
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  anal squamous carcinoma
     Methods 15 patients with anal squamous carcinoma were in our hospital during 1984-1998.Only 5 patients were diagnosed as cancer of anal canal in first time.
     方法北京医院1984-1998年间收治15例肛管鳞癌,首次诊断为肛管癌者仅5例。
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  “肛管鳞癌”译为未确定词的双语例句
     We have treated 60 cases of rare malignant anorectal tumors consisting of liomyosarcoma, malignant lymphoma, carcinoid, malignant melanoma, hasal cell carcinoma,anal canal squamous cell carcinoma,perianal mucinous adenocarcinoma during the period 1986-1995. It accounted for 4. 4% (60/1359) of the total malignant anorectal tumors treated in the same period.
     1986~1995年,收治直肠平滑肌肉瘤、直肠恶性淋巴瘤、直肠类癌、肛管直肠恶性黑色素瘤、一穴肛源癌、基底细胞癌、肛管鳞癌、原发性肛周粘液腺癌等8种少见的肛管直肠恶性肿瘤共60例。 占同期肛管直肠恶性肿瘤的4.4%(60/1359)。
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     However, this study failed to detect HPV in other anal cancers and rectal adenocarcinomas. We found that the HPV infection was not closely associated with the anal cancers in this group, however it existed in the anal glandular epithelium.
     研究表明本组肛管鳞癌与HPV感染关系不密切,但提示HPV可以感染腺上皮,为其与肛管腺癌关系研究提供了一条线索
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  相似匹配句对
     Anal and Perianal Squamous Cell Cancer Report of Thirteen Cases
     肛管及肛周13例分析
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     Diagnosis and Treatment of 15 Patients with Anal Squamous Carcinoma
     肛管的诊断与治疗(附15例分析)
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     , C.
     短苔草、C.
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     Melanoma of the Anorectum
     肛管直肠黑色素瘤
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     and squamous cell carcinoma was negative.
     阴性。
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  anal squamous carcinoma
Study of human papillomavirus infection in patients with anal squamous carcinoma
      
PURPOSE: The purpose of this study was to determine the incidence of human papillomavirus deoxyribonucleic acid (HPV DNA) in anal squamous carcinoma.
      


We have treated 60 cases of rare malignant anorectal tumors consisting of liomyosarcoma, malignant lymphoma, carcinoid, malignant melanoma, hasal cell carcinoma,anal canal squamous cell carcinoma,perianal mucinous adenocarcinoma during the period 1986-1995. It accounted for 4. 4% (60/1359) of the total malignant anorectal tumors treated in the same period. All these tumors were situated within 8 cm above the anal margin. The authors emphasize that digital examination and biopsy are of utmost importance in the...

We have treated 60 cases of rare malignant anorectal tumors consisting of liomyosarcoma, malignant lymphoma, carcinoid, malignant melanoma, hasal cell carcinoma,anal canal squamous cell carcinoma,perianal mucinous adenocarcinoma during the period 1986-1995. It accounted for 4. 4% (60/1359) of the total malignant anorectal tumors treated in the same period. All these tumors were situated within 8 cm above the anal margin. The authors emphasize that digital examination and biopsy are of utmost importance in the early diagnosis of malignant anorectal tumors.

1986~1995年,收治直肠平滑肌肉瘤、直肠恶性淋巴瘤、直肠类癌、肛管直肠恶性黑色素瘤、一穴肛源癌、基底细胞癌、肛管鳞癌、原发性肛周粘液腺癌等8种少见的肛管直肠恶性肿瘤共60例。占同期肛管直肠恶性肿瘤的4.4%(60/1359)。并就这些肿瘤的诊断与治疗进行了讨论。发现这些肿瘤均位于距肛缘8cm以下范围内,故强调肛指及活检的重要性。

In this study the polymerase chain reaction (PCR), dot blot hybridization (DBH), in situ hybridization (ISH) and immunohistochemistry (IMHC) techniques were applied to detect HPV DNA and antigen in 75 specimens of anal carcinomas. The results showed that in 19 squamous cell carcinomas (SCC), HPV,DNA was detected only in one case (5%, 1/19) by PCR, and was further identified as HPV 16 by DBH . HPV antigen was also found in this case. Positive staining was present not only in foci of the invasive tumour, but also...

In this study the polymerase chain reaction (PCR), dot blot hybridization (DBH), in situ hybridization (ISH) and immunohistochemistry (IMHC) techniques were applied to detect HPV DNA and antigen in 75 specimens of anal carcinomas. The results showed that in 19 squamous cell carcinomas (SCC), HPV,DNA was detected only in one case (5%, 1/19) by PCR, and was further identified as HPV 16 by DBH . HPV antigen was also found in this case. Positive staining was present not only in foci of the invasive tumour, but also in nonneoplastic superficial epithelium and nomal glands adjacent to the tumor. However, this study failed to detect HPV in other anal cancers and rectal adenocarcinomas. We found that the HPV infection was not closely associated with the anal cancers in this group, however it existed in the anal glandular epithelium.

用聚合酶链反应、斑点杂交、原位杂交、免疫组化技术检测72例肛管癌标本,PCR扩增19例鳞癌1例阳性(5%),斑点杂交证实为HPV16型,免疫组化发现HPV抗原不仅在癌巢中,还在癌周上皮浅层和正常腺体中分布,但原位杂交检测阴性。其余标本检测均呈阴性。研究表明本组肛管鳞癌与HPV感染关系不密切,但提示HPV可以感染腺上皮,为其与肛管腺癌关系研究提供了一条线索

Objective To investigate the factors related to diagnosis and treatment,15 patients with anal squamous carcinoma were analyzed.Methods 15 patients with anal squamous carcinoma were in our hospital during 1984-1998.Only 5 patients were diagnosed as cancer of anal canal in first time.In these 15 patients,11 received radiotherapy and chemotherapy,8 received Miles operation.Results 15 patients with anal squamous carcinoma were proven by pathologic examination,6 in NCCN (2003) stage Ⅰ, 4 in stage Ⅱ, 2 in stage ⅢA,...

Objective To investigate the factors related to diagnosis and treatment,15 patients with anal squamous carcinoma were analyzed.Methods 15 patients with anal squamous carcinoma were in our hospital during 1984-1998.Only 5 patients were diagnosed as cancer of anal canal in first time.In these 15 patients,11 received radiotherapy and chemotherapy,8 received Miles operation.Results 15 patients with anal squamous carcinoma were proven by pathologic examination,6 in NCCN (2003) stage Ⅰ, 4 in stage Ⅱ, 2 in stage ⅢA, 3 in stage ⅢB.Interstitial fibrosis of tumor tissue was shown by immunohistochemistry,(+++) was in 4 patients,(++) in 7 ones,(+) in 4 ones.The patients were followed in 10 year,average of survival time was (47±27.6) months.Conclusion Anus digital examination was emphasized for finding and diagnosis of the anal carcinoma.Radiotherapy and combined therapy including radiotherapy,chemotherapy and surgery are important treatments of the anal carcinoma.Staging,metastasis of inguinal lymph nodes,treatment,and interstitial fibrosis of tumor tissue affect the prognosis of anal squamous carcinoma patients.

目的探讨肛管癌诊断、治疗和预后的相关因素。方法北京医院1984-1998年间收治15例肛管鳞癌,首次诊断为肛管癌者仅5例。15例中行放疗化疗11例,8例行Miles手术。结果病理均证实为鳞癌。根据NCCN(2003年)分期,Ⅰ期6例,Ⅱ期4例,ⅢA期2例,ⅢB期3例。免疫组织化学染色显示肿瘤组织间质纤维化(+++)者4例,(++)者7例,(+)者4例。随诊最长10年,平均生存期(47±27.6)个月。结论肛门指诊是发现和诊断肛管癌的重要手段。放疗以及以放疗为主,化疗、手术为辅的综合治疗是肛管癌的主要治疗方法。肿瘤分期、腹股沟淋巴结转移、治疗方法以及肿瘤组织间质纤维化对病人的预后均有影响。

 
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