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| | Based on the paper of “the research on the theoretical models and calculation of vaporizing and heat killing therapy of cancer with laser",the author makes further research into the condition and method of extending the vaporizing area in cancer tumour,and have revised the formulas derived from the hypothesis that the vaporizing area is small.The revised formulas not only fit to the condition of small vaporizing area,but also fit to the condition of large one.Some suggestions as to medical clinic applicati... | | 作者在“激光汽化兼热杀癌肿瘤理论模型的研究及定量计算”一文的基础上,进一步研究了扩大癌肿瘤组织内汽化域的条件及方法。对该文在假设汽化域较小的条件下导出的公式作了修正,使之既适合汽化域较小的情况,同时也适合于汽化域较大的情况。本文还对光纤插入法汽化兼热杀癌肿瘤的临床医学应用提出了若干建议。 | | 文摘来源 | | Based on the theoretical models of vaporizing and heat killing therapy of cancer with laser,the theoretical calculations of three common thermal effect lasers have been made,and the results are shown and compared in this paper.We discuss on the applied methods to get the irradiating time as short as possible under more large vaporizing area.These theoretical calculated data will be valuable for reference. | | 本文根据激光汽化兼热杀癌肿瘤的理论模型〔1,2〕,对三种常见热效应激光进行了理论计算和结果对比 ,讨论了在较大汽化域情况下尽可能减少照射治疗时间的应用方法和措施 ,为激光治疗较大肿瘤提供具体理论参考数据 | | 文摘来源 | | Objective To investigate how the various factors affect interstitial laser hyperthermal lesions in liver,including the simplex factors considered by“the theoretical models of vaporizing and heat-killing therapy of cancer with laser”and the complex or changeable factors not considered by the theoretical models.The results could be used to provide the reference data for the safety operating of laser surgery.Methods Based on the theoretical models,the irradiating times(Nd∶YAG laser wavelength1060nm,power7W)had... | | 目的研究影响激光热毁损区的各种因素,包括“激光汽化兼热杀癌肿瘤理论模型”已考虑的近似简化条件、以及未考虑的复杂或可变因素,为激光手术安全操作提供参考依据。方法由理论模型计算Nd∶YAG激光功率为7W(波长1064nm)、汽化空腔直径(mm)为4.40、5.40、6.40、7.40时所需的照射时间。将Nd∶YAG激光裸光纤插入活体和离体犬肝、离体猪肝(增加8.40mm数据点)定时照射。照射后即刻沿光纤剖开标本,测量激光热毁损区域的大小,作统计学相关对比分析,建立线性回归方程。结果理论模型对汽化空腔大小的数值模拟结果在4.40~7.40mm范围内与实验数据基本符合。能用汽化空腔理论值进一步估计空腔外围瞬态凝固区域长短径的平均值。对空腔或凝固区长短径均值的Pearson积矩相关分析表明,活体与离体犬肝对比P<0.05,离体犬肝与离体猪肝对比P<0.01。汽化空腔的形状还与光纤末端侧面透光区长短、照射前初温、肝组织各向异性等有关。结论根据数学方法选择激光的功率和作用时间来实施激光$... | | 文摘来源 | |   | | << 更多相关文摘 |
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