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   肾癌 在 基础医学 分类中 的翻译结果: 查询用时:0.008秒
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肾癌
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  “肾癌”译为未确定词的双语例句
    UTILIZATION OF LEUCINE METHYL ESTER FOR THE GENERATION OF HYBRIDOMAS PRODUCING MONOCLONAL ANTIBODIES SPECIFIC TO KIDNEY AND SUBSETS OF RENAL CELL CARCINOMAS
    亮氨酸甲基酯处理法制备抗人肾癌单克隆抗体
短句来源
    The axudl gene consists of five exons and encodes a nuclear protein with 63kD molecular weight. It was frequently down-regulated in lung, kidney, liver and colon cancers compared with their corresponding normal tissues.
    该基因含有五个外显子,其编码产物为分子量63kD的细胞核内蛋白,该基因在肺癌、肾癌、肝癌和结肠癌中的表达较相应的正常组织均明显降低。
短句来源
    PCNA expression correlates with staging and grading of the tumor. The survival rate of higher PCNA expression (3 ̄4 grade) was lower than that of lower expression (1 ̄2 grade).
    肾癌组织的PCNA表达与肿瘤分期、分级均相关,PCNA高表达组(3~4级)术后5年生存率显著较PCNA低表达组(1~2级)短。
短句来源
    transferring FasL into GRC 1 cell may induced GRC 1 cell line to display cell apoptosis.
    转染 Fas L 基因可诱导肾癌 GRC- 1细胞凋亡
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  相似匹配句对
    Proliferating Cell Nuclear Antigen(Pc10) in Renal Cancer
    增殖细胞核抗原的研究
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    transferring FasL into GRC 1 cell may induced GRC 1 cell line to display cell apoptosis.
    转染 Fas L 基因可诱导 GRC- 1细胞凋亡
短句来源
    Important factors regulating the differentiation of kidney
    分化调控的相关因子
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    Anatomy of Aorticorenal Ganglia
    主动脉节的解剖
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    HISTOCYTOCHEMICAL STUDY OF CARCINOGENESIS OF CHEMICALLY INDUCED NASOPHARYNGEAL CARCINOMA IN RATS
    大鼠鼻咽变的组织化学
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The splenocyte of BALB/c mice, immunizedwith soluble and ovarian serous papillarycystedenoma-associated antigen CA_(925), was fusedwith NS-1 myeloma cell strain to produce amonoclonal antibody. 5 cell strains of the monoclonalantibody with continous secretion were obtained. Thefusion openings were used as code names. OC_(4D9),OC_(7E10), OC_(1B4), OC_(3B8) and OC_(9B9), their titers were1 : 10 ̄7, 1 : 1 0 ̄7, 1 : 10 ̄6, 1 : 10 ̄4 and 1 :10 ̄5 respectively. Ig subgroups were IgM and IgG. Thechromosomes showed the characteristics...

The splenocyte of BALB/c mice, immunizedwith soluble and ovarian serous papillarycystedenoma-associated antigen CA_(925), was fusedwith NS-1 myeloma cell strain to produce amonoclonal antibody. 5 cell strains of the monoclonalantibody with continous secretion were obtained. Thefusion openings were used as code names. OC_(4D9),OC_(7E10), OC_(1B4), OC_(3B8) and OC_(9B9), their titers were1 : 10 ̄7, 1 : 1 0 ̄7, 1 : 10 ̄6, 1 : 10 ̄4 and 1 :10 ̄5 respectively. Ig subgroups were IgM and IgG. Thechromosomes showed the characteristics of their par-ents. The 5 strains of the monoclonal antibody ob-tained presented specific reactions to CA_(925), no posi-tive reaction with normal ovarian tissues orleiomyoma of the uterus were seen, and there wereweak reactions with carcinomas of the lung, the stomach, thekidney, the esophagus and the rectum. Immunohistochemical tests proved that the monoclonal antibody produced wasspecific agains ovarian epithelial carcinoma, and itmight offer a means to the diagnosis and treatment ofmalignant ovarian tumors.

应用卵巢浆液性乳头状囊腺癌可溶性相关抗原CA_(925)免疫BALB/c小鼠,与NS-1骨髓瘤细胞株融合制各单克隆抗作(McAb),获得5株持续性分泌抗体的细胞株,以融合孔为代号,分别为OC_(4D9),OC_(7E10),OC_(1B4),OC_(3B8),OC_(9B9)。5种McAb的滴度分别为1:10 ̄7,1:10 ̄7,1:10 ̄6,1:10 ̄4,1:10 ̄5,免疫球蛋白亚型为IgM和IgG型,染色体呈双亲染色体特点。所获得5种McAb与CA_(925)有特异性反应(阳性反应);与正常卵巢组织及子宫平滑肌瘤未呈阳性反应;与肺癌、胃癌、肾癌、食管癌、直肠癌组织有弱阳性反应。

Proliferating cell nuclear antigen (PCNA) was arrayed by immunohistochemical methods in 53 cases of renal cancer,using 6 cases of renal angiomyolipoma and normal renal tissue for control.The results were as follows:No positive immunostaining cell was found in renal angiomyolipoma,a few cells in normal renal tissue were stained,and PCNA was expressed in all renal cancer specimens.PCNA expression correlates with staging and grading of the tumor.The survival rate of higher PCNA expression (3 ̄4 grade) was lower...

Proliferating cell nuclear antigen (PCNA) was arrayed by immunohistochemical methods in 53 cases of renal cancer,using 6 cases of renal angiomyolipoma and normal renal tissue for control.The results were as follows:No positive immunostaining cell was found in renal angiomyolipoma,a few cells in normal renal tissue were stained,and PCNA was expressed in all renal cancer specimens.PCNA expression correlates with staging and grading of the tumor.The survival rate of higher PCNA expression (3 ̄4 grade) was lower than that of lower expression (1 ̄2 grade).PCNA can judge the degree of differentiation and malignancy of neoplasms quantitively and may act as an independent criterion for the prognosis of renal cancer.

为探讨肾癌的生物学行为及预后,采用免疫组化ABC法对53例肾癌组织中PCNA进行检测,取6例肾错构瘤及正常肾组织作为对照。结果发现:肾错构瘤中未见PCNA着色,在正常肾组织中仅见少许细胞着色,而肾癌所有切片均呈阳性反应。肾癌组织的PCNA表达与肿瘤分期、分级均相关,PCNA高表达组(3~4级)术后5年生存率显著较PCNA低表达组(1~2级)短。PCNA可定量地判断肿瘤分化程度及恶性度,可作为肾癌预后判断的独立指标

おy treating the primed spleen cells with leucine methyl ester (LeuOMe),4 murine monoclonal antibodies (MAbs) was generated following immunization of mice with our own established human renal cancer cell line GRC1.LeuOMe can drastically improved the outgrowth of hybridomas.YD5,an IgG1 murine Mab,was of special insterest.YD5 is highly reactive with normal kidney and human renal cancer,and has little crossreactivity to nonrenal tissue.This procedure will be an option when production of MAb specific to cellsurface...

おy treating the primed spleen cells with leucine methyl ester (LeuOMe),4 murine monoclonal antibodies (MAbs) was generated following immunization of mice with our own established human renal cancer cell line GRC1.LeuOMe can drastically improved the outgrowth of hybridomas.YD5,an IgG1 murine Mab,was of special insterest.YD5 is highly reactive with normal kidney and human renal cancer,and has little crossreactivity to nonrenal tissue.This procedure will be an option when production of MAb specific to cellsurface antigen is intended and outgrowth of hybridoma is unexpectedly low.

以本所自建的肾癌细胞株(GRC1)作为免疫原,用亮氨酸甲基酯(LeuOMe)处理免疫后的脾细胞,可以显著提高细胞融合率,并且筛选到4株抗人肾癌单克隆抗体(MAb)。YD5为其中特异性较好的1株,属IgG1亚类,在正常肾组织的肾小管、大多数肾癌(13/15)组织中表达,且与其它被检正常组织交叉反应少。当以某些肿瘤细胞株作为免疫原且融合率很低时,用LeuOMe处理法来提高融合率是很有意义的

 
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