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精神活性物质依赖
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  “精神活性物质依赖”译为未确定词的双语例句
     RELATIONSHIP BETWEEN LEARNING,MEMORY AND RELAPSE OF PSYCHOLOGICAL ACTIVE SUBSTANCES
     应激、学习记忆与精神活性物质依赖及复发的关系
短句来源
     ROLE OF NON-TARGET RECEPTORS IN PSYCHOACTIVE SUBSTANCE DEPENDENCE
     非靶受体在精神活性物质依赖中的作用
短句来源
     This article mainly summarizes the functional and structural changes of these non-target receptors in the developing process of dependence on psychoactive substance,and discusses the mechanism of addiction. Furthermore,the research and development of new drugs that act on NMDA or histamine receptors as the target will open a new field of preventing and controlling opioid addiction.
     本文主要论述NMDA受体和组胺受体等非靶受体在精神活性物质依赖发生发展过程中功能和结构上的变化,探讨精神活性药物成瘾的机制,研究和开发以NMDA和组胺受体为靶标的新药,为阿片类药物成瘾的防治开辟新的研究领域。
短句来源
  相似匹配句对
     ROLE OF NON-TARGET RECEPTORS IN PSYCHOACTIVE SUBSTANCE DEPENDENCE
     非靶受体在精神活性物质依赖中的作用
短句来源
     One of the most abused substances in our country is opioid.
     在我国导致精神依赖活性物质主要是阿片类。
短句来源
     RELATIONSHIP BETWEEN LEARNING,MEMORY AND RELAPSE OF PSYCHOLOGICAL ACTIVE SUBSTANCES
     应激、学习记忆与精神活性物质依赖及复发的关系
短句来源
     STUDY ON PSYCHOACTIVE SUBSTANCES ADDICTION IN PSYCHOPHARMACOLOGICAL PROFILES
     精神活性物质成瘾的行为医学研究
短句来源
     PSYCHOACTIVE SUBSTANCE USE AMONG MEDICAL STUDENTS
     医学生使用精神活性物质状况分析
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At present,psychoactive substance abuse and addiction become more severe.It is not only a serious social issue,but also an important biological problem.One of the most abused substances in our country is opioid.The target receptor of psychoactive substance is opioid receptor and the non-target receptor mainly includes dopamine receptor,NMDA receptor,histamine receptor,and so on.This article mainly summarizes the functional and structural changes of these non-target receptors in the developing process of dependence...

At present,psychoactive substance abuse and addiction become more severe.It is not only a serious social issue,but also an important biological problem.One of the most abused substances in our country is opioid.The target receptor of psychoactive substance is opioid receptor and the non-target receptor mainly includes dopamine receptor,NMDA receptor,histamine receptor,and so on.This article mainly summarizes the functional and structural changes of these non-target receptors in the developing process of dependence on psychoactive substance,and discusses the mechanism of addiction.Furthermore,the research and development of new drugs that act on NMDA or histamine receptors as the target will open a new field of preventing and controlling opioid addiction.

当前精神活性物质滥用和成瘾呈上升趋势,它既是一个严重的社会问题,又是一个非常重要的生物学问题。在我国导致精神依赖的活性物质主要是阿片类。精神活性物质作用的靶受体为阿片受体,非靶受体主要包括多巴胺受体、N-甲基-D-门冬氨酸(NMDA)受体和组胺等。本文主要论述NMDA受体和组胺受体等非靶受体在精神活性物质依赖发生发展过程中功能和结构上的变化,探讨精神活性药物成瘾的机制,研究和开发以NMDA和组胺受体为靶标的新药,为阿片类药物成瘾的防治开辟新的研究领域。

This paper summarizes the advancement in the research of treatment of opioid dependence with electroacupuncture(EA) since 2003.This work,supported by a grant from the National Basic Research Programme(2003CB515407) of China,includes two parts,one is to investigate the effect of EA of different frequencies on morphine withdrawal syndrome(physical dependence) and morphine-induced conditioned place preference(psychic dependence) and their mechanisms in rats,another is to observe the effect of Han's acupoint nerve...

This paper summarizes the advancement in the research of treatment of opioid dependence with electroacupuncture(EA) since 2003.This work,supported by a grant from the National Basic Research Programme(2003CB515407) of China,includes two parts,one is to investigate the effect of EA of different frequencies on morphine withdrawal syndrome(physical dependence) and morphine-induced conditioned place preference(psychic dependence) and their mechanisms in rats,another is to observe the effect of Han's acupoint nerve stimulator(HANS),a device for transcutaneous nerve electric stimulation(TENS),on opiate withdrawal syndrome and craving for opiates in heroin addicts.

本文总结2003年以来在973基金(抗精神活性物质依赖和复发其他干预手段及其作用机理)支持下,我们进行的有关电针刺激抑制阿片依赖的研究进展。该研究内容分为阿片身体依赖和精神依赖两个方面。机制研究主要在吗啡依赖大鼠模型上进行,同时与临床人体观察互相配合(人体观察中关于脑影像的结果未包括在内)。鉴于综述思路上的系统性,本文也包括了2003年以前的2篇论文。

AIM:To test the reliability and validity of Dissociative Experiences Scale Ⅱ(DES-Ⅱ).METHODS:A total of 186 undergraduates selected from Sichuan University,Chengdu University of Traditional Chinese Medicine,Sichuan Normal College,Sichuan Education College,Sichuan Physical Education College and West-South Nationality College were interviewed from June 2003 to January 2004,who were selected by a senior attending physician according to the inclusion criteria and exclusion criteria.Inclusion criteria:①Undergraduates...

AIM:To test the reliability and validity of Dissociative Experiences Scale Ⅱ(DES-Ⅱ).METHODS:A total of 186 undergraduates selected from Sichuan University,Chengdu University of Traditional Chinese Medicine,Sichuan Normal College,Sichuan Education College,Sichuan Physical Education College and West-South Nationality College were interviewed from June 2003 to January 2004,who were selected by a senior attending physician according to the inclusion criteria and exclusion criteria.Inclusion criteria:①Undergraduates of Han ethnic.②Normal subjects without mental diseases,general medical diseases,chronic pain and psychoactive addiction in the past and at present,and have never been hypnotized.③ Patients with the total score less than 2 points respectively in Psychiatry Screening Inventory and Neurosis Screening Inventory(Three items were added into the Neurosis Screening Inventory,including acute stress reaction,post-trauma stress disturbance and hypochondria,considering the differences in perceptibility of hypnosis between patients with stress disturbance and hypochondria and normal people).Exclusion criteria:①Patients with a score of either screening inventory equal to or above 2 points.All subjects filled in the DES-Ⅱ and Tellegen Absorption Scale(TAS),and the Stanford Group Hypnotic Susceptibility Scale was used to assess the subjects.Six weeks later,38 subjects were re-tested with DES-Ⅱ.RESULTS:A total of 155 subjects accomplished the whole hynotization with three valid questionnaires,whose test data were involved in the analysis of results.The Cronbach coefficient α was 0.93 in Chinese DES-Ⅱ,and the split-half coefficient of Spearman-Brown was 0.88,which was 0.84 in the retest at 6 weeks later.Factor analysis showed that there were three main factors,which determined 32.16% of the total variance and respectively represented absorption and imaginative involvement,amnestic dissociation as well as the experiences of depersonalization and derealization respectively.After controlling factor of sex,the partial-correlation coefficient between DES-Ⅱ and SGHSS:C was 0.25(P < 0.05),and the partial-correlation coefficient between DES-Ⅱ and TAS was 0.32(P < 0.05=.CONCLUSION:DES-Ⅱ has good reliability and validity,while further research should be done to provide the data for criterion validity of DES-Ⅱ.

目的:对分离体验量表Ⅱ进行信度和效度的检测。方法:于2003-06/2004-01选择四川大学、成都中医药大学、四川师范学院、四川教育学院、成都体育学院、西南民族学院的志愿者186名。由高年资主治医生按照纳入标准和排除标准纳志愿者。纳入标准:①汉族在校大学生。②既往精神健康,无严重躯体疾病,无慢性疼痛史,无精神活性物质依赖史,没有被催眠的经历。③精神病筛选表及神经症筛选表对志愿者进行筛选表的得分均在2分以下(考虑到应激障碍和疑病症患者的催眠感受性与正常人不同,故在神经症筛选表中,加入了3个条目,分别是关于急性应激反应、创伤后应激障碍和疑病症)。排除标准:①在任何一个筛选量表上得分为2分及2分以上。被试填写分离体验量表Ⅱ及Tellegen专注量表,并用斯坦福团体催眠感受性量表对被试进行催眠测试。6周后对38名进行了分离体验量表Ⅱ量表重测。结果:完成催眠过程且三份问卷填写均有效的共有155名,155名被试的测试数据结均进入结果分析。分离体验量表Ⅱ量表中文版的克伦巴赫α系数为0.93,Spearman-Brown分半信度为0.88,6周后的重测信度为0.84。因子分析得出了3个主要因子,它们决定了总方差...

目的:对分离体验量表Ⅱ进行信度和效度的检测。方法:于2003-06/2004-01选择四川大学、成都中医药大学、四川师范学院、四川教育学院、成都体育学院、西南民族学院的志愿者186名。由高年资主治医生按照纳入标准和排除标准纳志愿者。纳入标准:①汉族在校大学生。②既往精神健康,无严重躯体疾病,无慢性疼痛史,无精神活性物质依赖史,没有被催眠的经历。③精神病筛选表及神经症筛选表对志愿者进行筛选表的得分均在2分以下(考虑到应激障碍和疑病症患者的催眠感受性与正常人不同,故在神经症筛选表中,加入了3个条目,分别是关于急性应激反应、创伤后应激障碍和疑病症)。排除标准:①在任何一个筛选量表上得分为2分及2分以上。被试填写分离体验量表Ⅱ及Tellegen专注量表,并用斯坦福团体催眠感受性量表对被试进行催眠测试。6周后对38名进行了分离体验量表Ⅱ量表重测。结果:完成催眠过程且三份问卷填写均有效的共有155名,155名被试的测试数据结均进入结果分析。分离体验量表Ⅱ量表中文版的克伦巴赫α系数为0.93,Spearman-Brown分半信度为0.88,6周后的重测信度为0.84。因子分析得出了3个主要因子,它们决定了总方差的32.16%,3个因子分别代表专注与想象性参与、遗忘性分离、人格解体及现实解体。在控制了性别因素后,分离体验量表Ⅱ与斯坦福团体催眠感受性量表C式的偏相关系数为0.25(P<0.05),与Tellegen专注量表的偏相关系数为0.32(P<0.05)。结论:分离体验量表Ⅱ有较好的信度和效度,进一步的研究需要提供分离体验量表Ⅱ的效标效度资料。

 
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