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基因注释
相关语句
  gene annotation
     Cut the neighboring sequence of SNPs and compare with the gene annotation database of NCBI to find their distribution among coding sequence, as well as the effects they have on amino acids coding.
     为了了解SNP对编码基因的影响,截取SNP位点两侧的序列与人类基因注释库进行序列的同源性比较,以了解SNP在编码区域及非编码区域的分布情况。
短句来源
  “基因注释”译为未确定词的双语例句
     Construction and Annotation of the JS5-BC Contig of Rice Sixth Chromosome S5 Locus and OS-APH Gene Analysis
     水稻第6染色体S5区重叠群构建、基因注释与OS-APH的克隆分析
短句来源
     Using the Visual Basic for Applications (VBA) language in Microsoft Excel 2003,we established a management system of macroprocessor-Management System of Sequences and Notation Database of Expressed Genes (MSSNDBEG),which could massively and automatically extract and process key items of data from the results of a large number of EST sequence and functional notation texts.
     以微软公司的数据处理软件Microsoft Excel 2003为平台,利用其VBA语言,我们编写了从大量基因注释文档结果中自动并大规模提取并处理关键信息项的宏程序系统一表达基因序列(EST)及其注释数据管理系统(Management System of Sequences and Notation Database of Expressed Sequence Tags,MSSNDBEST)。
短句来源
     We get 2878 tentative unique transcripts. And annotated the genes, blastN, analyzed the EST redundancy, classed the function of genes.
     文库中得到了2878条序列,对2878个基因进行基本的分析、序列的比对、功能注释、分析了表达基因的丰度、基因注释的情况、基因功能分类的情形;
短句来源
     After annotation of JS5-BC,46 gene loci were predicted.
     通过生物信息学方法,对JS5-BC进行了基因注释,确定该区域含有46个基因位点。
短句来源
     Vertebrate Gene Predictions and the Problem of Large Genes
     脊椎动物基因注释中的大基因问题
短句来源
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  相似匹配句对
     4 new genes were obtained.
     U基因
短句来源
     UBROAD:A Web Based Platform of Gene and Protein Data
     基因和蛋白质的批量注释系统UBROAD
短句来源
     Vertebrate Gene Predictions and the Problem of Large Genes
     脊椎动物基因注释中的大基因问题
短句来源
     Genetic Information Carrier Gene
     基因简史
短句来源
     supplementing the history annotations;
     增加沿革注释 ;
短句来源
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  gene annotation
Using gene annotation information of TIGR, a putative resistance gene was identified in the BAC clone OSJNBa0028L05 and the sequence information was used to generate STS marker 7312.T4A.
      
To finely map the Avr gene, two additional candidate avirulence gene (CAG) markers, CAG6-1 and CAG6-2, were developed based on the gene annotation of the sequence of TEL 11.
      
Variation analysis and gene annotation of eight MHC haplotypes: The MHC Haplotype Project
      
The gene annotation uncovered haplotype-specific differences and confirmed the presence of more than 300 loci, including over 160 protein-coding genes.
      
Among the tools developed at TAIR, the most notable is the Sequence Viewer, which displays gene annotation, clones, transcripts, markers and polymorphisms on the Arabidopsis genome, and allows zooming in to the nucleotide level.
      
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A method has been developed for extracting and purifying genomic DNA from environmental samples.In this method,an environmental sample is treated first by grinding and freezing/thawing and subsequently by SDS/proteinase K\|based DNA extraction.The yields of purified DNA from three samples used in this study ranged from 2 to 16μg per gram of dry sample.Mixed genomic DNA libraries for two of the environmental samples were constructed by inserting restriction fragements (3~8 kb) of the purified DNAs into plasmid...

A method has been developed for extracting and purifying genomic DNA from environmental samples.In this method,an environmental sample is treated first by grinding and freezing/thawing and subsequently by SDS/proteinase K\|based DNA extraction.The yields of purified DNA from three samples used in this study ranged from 2 to 16μg per gram of dry sample.Mixed genomic DNA libraries for two of the environmental samples were constructed by inserting restriction fragements (3~8 kb) of the purified DNAs into plasmid pUC18 and transforming \%E.coli\% DH5α with the resultant plasmids.Approximately 10 3 to 10 4 insert\|containing clones were obtained from 1g of cach sample.Clone libraries were analyzed by DNA sequencing and gene annotation.Among 20 randomly\|selected clones, 14 contained an insert whose sequence had not been reported while the rest had an insert of either E.coli or vector origin.A search of sequence databases using the end sequences of each of the foreign inserts showed that each sequence was part of a gene encoding,in most cases, a predictable function.Our results are of significance to the collection,investigation and exploitation of the genes of uncultured microorganisms.

采用研磨 /冻融和SDS/蛋白酶K热处理等理化方法 ,直接从性质不同的环境样品中提取和纯化混合基因组DNA。所获得纯品DNA的产量为每克样品 2~ 1 6μg。对纯品DNA进行限制性内切酶处理后 ,构建了以pUC1 8为载体的DNA文库。建库效率为从每克环境样品获得约 1 0 3~ 1 0 4 个含 3~ 8kb外源随机插入片段的克隆。通过DNA序列测定和基因注释 ,对从文库中随机选取的克隆进行了分析 ,发现外源插入片段均含序列未见报道的新基因。本文所做的尝试对于保存、研究和开发未培养微生物基因资源具有意义

In the post-genomic era,with the accomplishment of the sequence mapping of human genome,one of the most important tasks for life science is the explanation and identification of human genome,that is,about 1/3genes of human genome and their functions need further revealment and verific-ation on the level of protein.In the field of functional proteomics,the human disease proteomics shows great potential in the discovery of new molecular targets and biomarkers for medicine and biopharmacy.In this article,we...

In the post-genomic era,with the accomplishment of the sequence mapping of human genome,one of the most important tasks for life science is the explanation and identification of human genome,that is,about 1/3genes of human genome and their functions need further revealment and verific-ation on the level of protein.In the field of functional proteomics,the human disease proteomics shows great potential in the discovery of new molecular targets and biomarkers for medicine and biopharmacy.In this article,we have made a concise discussion on the current status,existing problems and future development in the research of human disease proteomics both in and out of China.

在人类基因组草图完成的后基因组时代,生命科学面临的最重要任务之一将是对人类基因的注释与确认,即人类基因组中约1/3的基因及其功能有待于蛋白质水平上的揭示与确认。其中,在功能蛋白质组领域内,疾病蛋白质组学在医学和生物制药方面具有发现新分子药靶、生物标志物的巨大的潜力。本文对疾病蛋白质组学在国外、国内研究现状及目前所存在的问题、发展趋势等几方面作简要概述。

The life science has entered the era of post-genomics.One of the most important tasks of present life science research is to annotate and verify human genomic data already obtained.Microarrays of DNA and protein and lab-on-chip all play crucial roles in uncovering the functions of the genomes and in analyzing the specific genomic relationships of the interacting networks.At the same time, microarray technologies can provide tremendous amount of data for biomedical researchers, and is becoming an ever-powerful...

The life science has entered the era of post-genomics.One of the most important tasks of present life science research is to annotate and verify human genomic data already obtained.Microarrays of DNA and protein and lab-on-chip all play crucial roles in uncovering the functions of the genomes and in analyzing the specific genomic relationships of the interacting networks.At the same time, microarray technologies can provide tremendous amount of data for biomedical researchers, and is becoming an ever-powerful tool for system biology.All these shall contribute to the eventual elucidation of the functional genomics.

生命科学研究已进入后基因组时代,当前最重要的任务之一是对人类基因的注释与确认。基因芯片、蛋白质芯片及芯片实验室在揭示基因功能中将发挥重要作用。同时。生物芯片技术为系统生物学的发展提供大量数据,并成为系统生物学研究强有力的工具,为最终破解基因功能指明了方向。

 
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