Objective To study the relationship between the expression of P50 proteins of nuclear transcription factor kappa B(NF-κB),its suppressor protein IκBα and the infiltration, metastasis of esophageal squamous cell carcinoma.
Conclusion A significant positive correlation exist between the expression of Tiam1 and the gastric carcinoma infiltration and metastasis as well as among kinds of clinical pathological factors, so the expression of Tiam1 can provide valuable reference for the prevention of infiltration, metastasis and the decision of prognosis.
Objective: To study the expression of MCP-1 in colorectal carcinoma and its relationship to the infiltration of the macrophage and to the biological behaviour of infiltration and metastasis of colorectal carcinoma.
Conclusion: The expression of chemokine MCP-1 in colorectal carcinoma may influence its biological behaviour of infiltration and metastasis, and can attract the immuno-cell to the local of the tumor, such as Macrophage.
The most important prognostic factors are size >amp;gt;5 cm, tumor necrosis, infiltration and metastasis to other sites, mitotic count >amp;gt;1-5 per 10 high-powered fields, and most recently, mutation in the c-kit gene.
In our work, it was apparent that MUC1 expression was associated with PLC cell infiltration and metastasis as well.
Both E-Cadherin and β-Catenin were proved respectively with tumor suppressor effect against invasiveness and metastasis.
The results were correlated with the frequency of cell proliferation and with clinicopathological characteristics such as degree of differentiation, invasiveness and metastasis.
The correlation of p53 and nm23-H1 expression with invasiveness and metastasis in esophageal carcinoma
Malignant progression is the process by which tumor cells acquire more malignant properties, such as invasiveness and metastasis, during tumor development.
These data suggest that TFPI-2 is critical for the invasion and metastasis of lung cancer and that the downregulation of TFPI-2 production may be a feasible approach to increase invasiveness and metastasis.