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寻常银屑病
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  psoriasis vulgaris
     Results: ① HLA-DRB1*07 allele was markedly correlated with psoriasis vulgaris from Baotou(P<0.01,OR=2.72); ② There is no difference of distribution between cases with typeI and typeII psoriasis vulgaris,,,,(χ~2=0.16 P>0.05).
     结果①HLA-DRB1*07与包头市汉族寻常型银屑病患者具有明显的相关性(P<0.01,OR=2.72)②HLA-DRB1*07在Ⅰ型、Ⅱ型寻常银屑病患者中分布无差异(χ2=0.16,P>0.05)。
短句来源
     Efficacy of treatment with calcipotriol/betamethasone dipropionate followed by calcipotriol alone compared with tacalcitol for the treatment of psoriasis vulgaris: A randomised, double-blind trial
     单纯用钙泊三醇后再用钙泊三醇/倍他米松二丙酸盐与Tacalcitol治疗寻常银屑病疗效比较:随机双盲试验
短句来源
     Results:1)Drugs, infection,stress,moisture, drinking,sea food, vaccination, smoking and trauma were risk induced factors of primary psoriasis vulgaris;
     结果 :  (1 )寻常银屑病首发诱因为 :服药、感染、精神紧张、受潮、嗜酒、吸烟、食鱼虾、接种疫苗及外伤 (P <0 .0 5 ) ;
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  “寻常银屑病”译为未确定词的双语例句
     The abnormality of serum immunoglobulin also suggests that there are disturbance of humoral immunity in psoriasis and that vulgar psoriasis is related to human autoimmunizatian in some way.
     寻常银屑病患者血清免疫球蛋白的变化也进一步说明寻常型银屑病存在体液免疫功能紊乱,检测的结果从一个侧面支持了寻常型银屑病并发病与自身免疫有关。
短句来源
     Conclusion The results suggested that increased dermal mast cell and elevated levels of IL-8 and RANTES in the keratinocytes of psoriatic lesions may play an important role in the pathogenesis of psoriasis.
     结论结果提示MC、IL-8和RANTES可能参与寻常银屑病的致病过程; 真皮MC密度的增加与表皮中IL-8的趋化有关。
短句来源
  相似匹配句对
     Analyses of Genetic Epidemiology of Psoriasis Vulgaris
     寻常银屑病遗传流行病学分析
短句来源
     Case-merely Study on Psoriasis Vulgaris
     寻常银屑病单纯病例研究
短句来源
     Psoriatic arthritis
     银屑病关节炎
短句来源
     PSORIASIS IN THE AGED
     老年银屑病
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  psoriasis vulgaris
Clinical observation on effect of triptolide tablet in treating patients with psoriasis vulgaris
      
Objective: To investigate the effects of triptolide tablet in the treatment of patients with psoriasis vulgaris.Methods: By an open clinical study of 103 patients with psoriasis vulgaris.
      
Expression of CC chemokine ligand 20 and CC chemokine receptor 6 mRNA in patients with psoriasis vulgaris
      
The skin biopsies were collected from skin lesions in 35 cases of psoriasis vulgaris and 18 normal controls.
      
Expression of LL-37, human beta defensin-2, and CCR6 mRNA in patients with psoriasis vulgaris
      
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This article deals with the study of the content of plasma middle molecular substance (MMS) in patients with vulgaris psoriasis (±S,292.6±16.8u/dl,n=47), The result shows that their content is noticeably higher than that in normal controlled group(±SD, 224±24u/dl, n=187), and the content in progressive group (±SD, 304±57u/dl, n=37) remarkabiy higher than that in silent group (±SD, 252±38u/dl, n=10). Prompt: The content of plasma MINTS has relevant parallel relations to the seriousness of psoriasis. The determination...

This article deals with the study of the content of plasma middle molecular substance (MMS) in patients with vulgaris psoriasis (±S,292.6±16.8u/dl,n=47), The result shows that their content is noticeably higher than that in normal controlled group(±SD, 224±24u/dl, n=187), and the content in progressive group (±SD, 304±57u/dl, n=37) remarkabiy higher than that in silent group (±SD, 252±38u/dl, n=10). Prompt: The content of plasma MINTS has relevant parallel relations to the seriousness of psoriasis. The determination of the content of plasma MMS can be regarded as a biochemical index to determine the change of the disease, to evaluate the curative effect and to judge prognosis.

本文研究了寻常银屑病患者血浆中分子(MMS)含量(±SD为292.6±16.8u/dl,n=47,显著高于正常对照组(±SD为224±24u/dl,n=187)。而进行期组血浆MMS含量(±SD)为304±57u/dl,(n=37),静止期组血浆MMS含量(±SD)为252±38u/dl,(n=10),统计结果,进行期组血浆MMS含量显著高于静止期组(P<0.01),静止期组MMS含量显著高于对照组(P<0.01),提示:血浆MMS含量与银屑病的严重程度有相应的平行关系,血浆MMS含量升高的幅度与病情的严重程度大体一致,其含量测定拟可作为监测该病病情活动,评价疗效和判断预后的生化指标。

Objective:To determine the risk factors of psoriasis vulgaris.Methods:Using case control study,182 primary psoriatics and 603 recurrent psoriatics were investigated with 647 healthy people as control.Results:1)Drugs, infection,stress,moisture, drinking,sea food, vaccination, smoking and trauma were risk induced factors of primary psoriasis vulgaris; 2)The risk induced factors of recurrent psoriasis vulgaris were the same as those of primary psoriasis vulgaris, except for trauma; 3)Smoking and drinking, as...

Objective:To determine the risk factors of psoriasis vulgaris.Methods:Using case control study,182 primary psoriatics and 603 recurrent psoriatics were investigated with 647 healthy people as control.Results:1)Drugs, infection,stress,moisture, drinking,sea food, vaccination, smoking and trauma were risk induced factors of primary psoriasis vulgaris; 2)The risk induced factors of recurrent psoriasis vulgaris were the same as those of primary psoriasis vulgaris, except for trauma; 3)Smoking and drinking, as risk induced factors of posriasis vulgaris, presented a significant difference between men and women; 4)High risk induced factors of primary psoriasis vulgaris were infection, drugs, trauma and drinking. Conclusion :The authors suggested that environmental factors play an important role in the onset of psoriasis vulgaris. [

目的 : 研究寻常型银屑病的诱因。方法 : 采用病例对照研究方法 ,调查了 1 82例寻常型银屑病首发患者、6 0 9例复发患者及同一地区的健康对照 6 47例 ,对寻常型银病的诱发因素进行了研究。结果 :  (1 )寻常银屑病首发诱因为 :服药、感染、精神紧张、受潮、嗜酒、吸烟、食鱼虾、接种疫苗及外伤 (P <0 .0 5 ) ;(2 )寻常银屑病复发诱因为 :精神紧张、受潮、嗜酒、吸烟、食鱼虾、服药、接种疫苗、感染 (P <0 .0 5 ) ;(3)诱发寻常型银屑病的环境因素在男女间存在显著性差异的为嗜酒及吸烟 ;(4)银屑病首发更重要的诱因为 :感染、服药、外伤及嗜酒 (P <0 .0 5 )。结论 : 环境因素可能在寻常型银屑病的发病中起一定作用

Objective: To study the relationship between psoriasis and β2-microglobulin. Methods: The serum levels of β2-mi-croglobulin were determined by radioimmunoassay in 80 patients with vulgar psoriasis. Serum levels of immunoglobulin were also tested. Reasults: The serum level of β2-microglobulin was significantly higher in the psoriasis patients than in control group.The level was higher in the progressive stage than in the stable stage;it was higher in geographic.The serum level of IgA was significantly higher...

Objective: To study the relationship between psoriasis and β2-microglobulin. Methods: The serum levels of β2-mi-croglobulin were determined by radioimmunoassay in 80 patients with vulgar psoriasis. Serum levels of immunoglobulin were also tested. Reasults: The serum level of β2-microglobulin was significantly higher in the psoriasis patients than in control group.The level was higher in the progressive stage than in the stable stage;it was higher in geographic.The serum level of IgA was significantly higher in the psoriasis patients than in control group.The serum level of IgM was lower in the psoriasis patients than in control group. Conclusion: there were autoantibodies to keratinocyte and lymphocyte in the serum of psoriasis vulgar patients.The destruction of these cells led to more β2-M in the serum, especially in progressive stage. There are some autoantibodies in the serum of patients with vulgar psoriasis, in stable stage, too, which led to more β2-M in the serum, and the increase of β2-M accounts for the alteration of stable stage and progressive stage in patients with psoriasis in some degree, and the reasan of the higher ratio of psoriasis in the cured psoriasis patients than healthy man. The abnormality of serum immunoglobulin also suggests that there are disturbance of humoral immunity in psoriasis and that vulgar psoriasis is related to human autoimmunizatian in some way.

目的:为明确银屑病与β_2微球蛋白(β_2-M)之间的关系。方法:对确诊的80例寻常型银屑病患者进行血清β_2-M水平的检测,同时测定了血清免疫球蛋白的浓度。β_2-M的检测采用125放射免疫分析法。结果:寻常型银屑病血清β_2-M水平显著性增高。尤以进展期为甚(与对照组比较,P值均<0.01),进展期升高又较稳定期明显(P<0.01)。地图状较点滴状高(P<0.01)。寻常型银屑病血清免疫球蛋白IgA浓度显著高于对照组(P<0.01)。而IgA浓度则显著低于对照组(P<0.05)。结论:从检测结果分析,寻常型银屑病患者血清中存在的自身抗体,可能包括角朊细胞,淋巴细胞等在内的有核细胞过多地破坏,使得血清β_2-M浓度显著升高,尤以进展期为甚。寻常型稳定期银屑病患者体内可能也存在一定量自身抗体。使得血清β_2-M浓度升高,一定程度上解释了临床上银屑病稳定期和进展期反复交替的现象,以及治愈的银屑病复发率比正常的人群发病率高的可能原因。寻常银屑病患者血清免疫球蛋白的变化也进一步说明寻常型银屑病存在体液免疫功能紊乱,检测的结果从一个侧面支持了寻常型银屑病并发病与自身免疫有关。

 
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