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原发性骨关节炎
相关语句
  primary osteoarthritis
     The morbidity of primary osteoarthritis is higher in the elderly , especially the os-teoarthritis of Knee is the more common.
     原发性骨关节炎在老年人中发病率较高,而膝骨关节炎又更为常见。
短句来源
     Conclusions Estradiol metabolism may attribute to the pathogenesis of primary osteoarthritis.
     结论 原发性骨关节炎的发病机制可能与雌激素的代谢有关
短句来源
     Conclusion:Those results suggested that IGF-I is an important regulator for growth and development of articular cartilage. IGF-I metabolism may attribute to the pathogenesis of primary osteoarthritis.
     结论 :IGF -I是关节软骨生长发育的重要调节因子 ,IGF -I的代谢可能与原发性骨关节炎的发病机制有关。
短句来源
     Conclusion Biochemical features of primary osteoarthritis in serum and cartilage change significantly with age.
     结论原发性骨关节炎血清及软骨生化指标随年龄增高改变明显。
短句来源
     Estradiol metabolism may attribute to the pathogenesis of primary osteoarthritis.
     雌激素代谢可能与原发性骨关节炎的发病机制有关。
短句来源
  spontaneous osteoarthritis
     Observation on Histopathological and Histochemical Features of Spontaneous Osteoarthritis in Guinea Pigs of Different Age
     不同月龄豚鼠原发性骨关节炎的病理变化
短句来源
     [Objective] To observe the dynamic changes in histopathological and histochemical features of spontaneous osteoarthritis(OA) in guinea pigs.
     [目的]观察豚鼠原发性骨关节炎(osteoarthritis,OA)病理和组织化学的动态变化,有助于OA病理机制和防治效果的研究。
短句来源
  “原发性骨关节炎”译为未确定词的双语例句
     Observation on Biochemical Features of P rimary Osteoarthritis of Guinea Pigs
     豚鼠原发性骨关节炎的生化研究
短句来源
     [Conclusion] No obvious signs of OA were discernible in the guinea pigs aged younger than three months old. Histopathological and histochemical changes of articular cartilage were developed in animals aged 3 and 4 months. Degenerative joints were found in 5 and 6-month old animals.
     [结论]0.5-2月龄的Hartley豚鼠未发现明显的原发性骨关节炎病理改变,3-4月龄的变化较明显,5-6月龄的豚鼠骨关节发生退行性变。
短句来源
     Excluded other etiological factors,some of them were finally diagnosed as idiopathic osteoarthritis of knee if they had clinical symptoms and a radiographic grade above Kellgren & Lawrence Ⅱ grade.
     并安排被调查对象拍双膝正侧位X射线片。 根据问卷内容确实有临床症状,且放射学X射线片显示Kellgren&Lawrence分级≥Ⅱ级的,排除继发性骨关节炎后,可以确诊膝原发性骨关节炎
短句来源
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  primary osteoarthritis
This series involved 53 prostheses implanted in patients solely with primary osteoarthritis (OA) of the shoulder who had been reviewed clinically and radiologically.
      
Primary osteoarthritis (OA) is a polygenic disease associated with age and obesity.
      
In most cases of these diseases and in primary osteoarthritis, there are mineral deposits in the cartilage, mineral crystals in the synovial fluid, and aberrations of pyrophosphate metabolism.
      
In a prospective non-randomized consecutive study, 34 patients with primary osteoarthritis of the knee underwent TKR.
      
Radiological evaluation of the proximal tibiofibular joint in knees with severe primary osteoarthritis
      
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  spontaneous osteoarthritis
Histological study of spontaneous osteoarthritis in the knee joint of guinea pigs
      
The guinea pig represents a useful animal model of spontaneous osteoarthritis (OA).
      
Anin vivo investigation of the effect of anthraquinones on the turnover of aggrecans in spontaneous osteoarthritis in the guinea
      
Since the guinea pig develops spontaneous osteoarthritis, this may give useful information on the potential for such compounds to inhibit the progression of osteoarthritis.
      
Bilateral spontaneous osteoarthritis of the stifle joint was observed to cause progressive lameness in 3 Holstein-Friesian and 52 Jersey cows 5-13 years old.
      


The morbidity of primary osteoarthritis is higher in the elderly , especially the os-teoarthritis of Knee is the more common. The author has worded in Yemen for 2years and divided the patients with osteoarthritis of knee in to three groups, according to clinicmanifestation. Treatment with medicine, local block or ostedectomy at upper end of tibia was given separately. In the second group the "cord-like"node is panniculitis which resulted from chronic accumulating minor injury, which was effecitve treated y prednisoplone....

The morbidity of primary osteoarthritis is higher in the elderly , especially the os-teoarthritis of Knee is the more common. The author has worded in Yemen for 2years and divided the patients with osteoarthritis of knee in to three groups, according to clinicmanifestation. Treatment with medicine, local block or ostedectomy at upper end of tibia was given separately. In the second group the "cord-like"node is panniculitis which resulted from chronic accumulating minor injury, which was effecitve treated y prednisoplone. The indication of osteoectomy at upper end of tibia is the cases com-plained rest pain associated with or without bowleg or Knock-Knee, because after osteoeetomy can de-crease intraosteous pressure, and also correct the deformity . This kind of operation is easy and sim-ple.the curative effect is satisfactory.

原发性骨关节炎在老年人中发病率较高,而膝骨关节炎又更为常见。作者在也门共和国工作2年中对也门原发性股骨关节炎发病率高的原因进行了分析,并将所遇见之原发性膝骨关节炎病人分为3类,分别给予药物、局封和胫骨上端截骨治疗。对局封病例中,体检时所发现的膝关节周围(多见于膝外上方)的疼痛性“绳索样”物,认为是慢性积累性微小损伤产生的“脂膜炎”,因此用Prednisonlne治疗有效。胫骨上端截骨尤为适合有休息痛,合并膝内、外翻畸形者,因截骨后可降低骨内压和矫正畸形。此类手术简单易行,不需特殊器械,疗效确切。

Objective To study the ultrastructural and biochemical changes of primary osteoarthritis of the knee joint in guinea pigs, and investigate its early pathogenesis. Methods 30 female Hartley guinea pigs aged 1 ~ 7 months were divided into postnatal 1 months,postnatal 3 months and postnatal 7 months groups, with 10 animals each. The degeneration of the knee joint cartilage was observed by scanning electron microscope. Proteoglycan and estradiol in serum were measured by ELISA. Results Remarkable degeneration...

Objective To study the ultrastructural and biochemical changes of primary osteoarthritis of the knee joint in guinea pigs, and investigate its early pathogenesis. Methods 30 female Hartley guinea pigs aged 1 ~ 7 months were divided into postnatal 1 months,postnatal 3 months and postnatal 7 months groups, with 10 animals each. The degeneration of the knee joint cartilage was observed by scanning electron microscope. Proteoglycan and estradiol in serum were measured by ELISA. Results Remarkable degeneration of the knee joint cartilage was seen in guinea pigs of 3 months old. Serum estradiol level was high 1 month postnatal, and increased with age. The level of proteoglycan was lower in animals of 3 months old than in animals of 1 month old, and decreased with age.Conclusions Estradiol metabolism may attribute to the pathogenesis of primary osteoarthritis.

目的 通过动态观察豚鼠软骨降解的形态学与血液生物化学的改变 ,探讨骨性关节炎的早期病变机制。方法 选用 Harlty雌性豚鼠 30只 ,分为出生后 1、3、7个月组 ,每组各 10只。在扫描电镜下 ,观察 3组豚鼠膝关节软骨的降解情况 ,并测定其血清蛋白聚糖 GI区和雌二醇的水平。结果  3个月组关节软骨即有严重降解。 1个月组豚鼠的雌二醇水平已达到较高浓度并随着年龄的增长而升高。出生3个月组软骨严重破坏时 ,蛋白聚糖也明显低于出生 1个月组软骨正常时的水平 ,并随着年龄的增长而继续下降 ,各组间的差异均有非常显著性意义 (P <0 .0 1)。结论 原发性骨关节炎的发病机制可能与雌激素的代谢有关

Objective: To study the role of insulin-like growth factor I(IGF-I)in early pathogenesis of primary osteoarthritis (OA) in guinea pigs.Methods:30 female Hartley guinea pigs were divided into postnatal 1,3 and 7 months groups,with 10 animals in each group.The degeneration of knee joint cartilage was observed and the serum IGF-I was determined by radioimmunoassay (RIA).Linear correlation between variables was tested by calculating groups correlation coefficient.Results:Remarkable degeneration of knee joint cartilage...

Objective: To study the role of insulin-like growth factor I(IGF-I)in early pathogenesis of primary osteoarthritis (OA) in guinea pigs.Methods:30 female Hartley guinea pigs were divided into postnatal 1,3 and 7 months groups,with 10 animals in each group.The degeneration of knee joint cartilage was observed and the serum IGF-I was determined by radioimmunoassay (RIA).Linear correlation between variables was tested by calculating groups correlation coefficient.Results:Remarkable degeneration of knee joint cartilage was seen in guinea pigs of 3 months old.The level of serum IGF-I increased with age and significant difference were seen in three groups (p<0.01).The concentration of serum IGF-I was correlated with the age of guinea pigs (r=0.56,p<0.001).Conclusion:Those results suggested that IGF-I is an important regulator for growth and development of articular cartilage.IGF-I metabolism may attribute to the pathogenesis of primary osteoarthritis.

目的 :探讨胰岛素样生长因子I(IGF -I)在豚鼠原发性骨性关节炎早期病变机制中的作用。方法 :Hartley雌性豚鼠 3 0只 ,以出生后 1、3、7月分 3组 ,每组 10只。观察豚鼠膝关节软骨降解情况 ,用线性相关分析法分析各组变量间的相关关系。结果 :3个月组豚鼠关节软骨即有严重降解 ,其血清IGF -I水平随年龄段的增长而升高 ,各组间差异非常显著 ( p <0 .0 1)。 3组豚鼠血清IGF -I与其年龄呈显著正相关 (r =0 .5 6,p <0 .0 0 1)。结论 :IGF -I是关节软骨生长发育的重要调节因子 ,IGF -I的代谢可能与原发性骨关节炎的发病机制有关。

 
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