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   前列腺间质肉瘤 在 肿瘤学 分类中 的翻译结果: 查询用时:0.638秒
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前列腺间质肉瘤
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  “前列腺间质肉瘤”译为未确定词的双语例句
    A TUMOR ORIGINATES FROM SPECIALIZED PROSTATIC STROMA - PROSTATIC STROMAL SARCOMA
    前列腺间质肉瘤──一种由特异性间质细胞发生的肿瘤
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    Results PSS originated in specialized prostatic stroma.
    结果前列腺间质肉瘤是发生于前列腺特异性间质细胞的肿瘤。
短句来源
    conclusions The histologic features and immunohistochemical profile of PSS are different from other mesenchymal lesions of the prostate.
    结论 前列腺间质肉瘤是一种在组织学特征及免疫组化表型上都不同于其他间叶性肿瘤的激素依赖性肿瘤。
短句来源
    Some of them were followed up. Results Of the 16 cases, 6 presented stromal nodular hyperplasia, 3 were stromal sarcoma, 1 malignant phyllodes type tumor, 3 leiomyosarcoma, 1 fibrosarcoma, and one non Hodgkin′s lymphoma.
    结果  16例中诊断前列腺间质结节 6例 ,前列腺恶性分叶状肿瘤 1例 ,前列腺间质肉瘤 3例 ,前列腺平滑肌肉瘤 3例 ,纤维肉瘤 1例 ,前列腺非霍奇金恶性淋巴瘤 2例。
短句来源
    The phyllodes type tumors are often confused with stromal sarcomas in needle biopsy specimens and cause difficulty in differential diagnosis.
    在穿刺的标本中 ,前列腺叶状囊肉瘤易与前列腺间质肉瘤混淆 ,前列腺间质肉瘤以无特定结构的小梭形细胞为特点。
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Objective To study the clinical pathological characterisites and the diagnosis of prostatic stromal sarcoma (PSS). Methods The clinicopathologic features and immnunohistochemical profile of 2 cases of PSS were studied. Results PSS originated in specialized prostatic stroma. It occurred in males above 60 years old. The histologic features of PSS were characterized by highly proliferative specialized prostatic stroma with moderate to high degree of cytological atypia, and associated with non-neoplastic prostatic...

Objective To study the clinical pathological characterisites and the diagnosis of prostatic stromal sarcoma (PSS). Methods The clinicopathologic features and immnunohistochemical profile of 2 cases of PSS were studied. Results PSS originated in specialized prostatic stroma. It occurred in males above 60 years old. The histologic features of PSS were characterized by highly proliferative specialized prostatic stroma with moderate to high degree of cytological atypia, and associated with non-neoplastic prostatic glandular elements. Immunohistochemical staining of Vimentin, CD34 and PR were positive. conclusions The histologic features and immunohistochemical profile of PSS are different from other mesenchymal lesions of the prostate. It is a hormonal responsive tumor, which originates from prostatic specialized stroma. [

目的 探讨前列腺间质肉瘤的临床病理特征。方法对两例该肿瘤作常规HE染色及免疫组织化学标记,在光镜下观察组织学形态及免疫组化表达。结果前列腺间质肉瘤是发生于前列腺特异性间质细胞的肿瘤。发病高峰在老年人(50~69岁)。镜下肿瘤组织以间质细胞高度增生伴中-高度异型为特征。病变内可含良性前列腺腺体成分,类似于乳腺的叶状囊肉瘤。免疫组化表达Vimentin,CD34及PR阳性。结论 前列腺间质肉瘤是一种在组织学特征及免疫组化表型上都不同于其他间叶性肿瘤的激素依赖性肿瘤。激素治疗有效。应将其作为一种独立的肿瘤诊断。

Objective To investigate the diagnosis, differential diagnosis and prognosis of stromal tumors and tumor like lesions of the prostate. Methods By means of HE, immunohistochemistry and electron microscopy, the clinical and histological data of 16 cases with stromal tumors and tumor like lesions of the prostate were observed. Some of them were followed up. Results Of the 16 cases, 6 presented stromal nodular hyperplasia, 3 were stromal sarcoma, 1 malignant phyllodes type tumor, 3 leiomyosarcoma, 1 fibrosarcoma,...

Objective To investigate the diagnosis, differential diagnosis and prognosis of stromal tumors and tumor like lesions of the prostate. Methods By means of HE, immunohistochemistry and electron microscopy, the clinical and histological data of 16 cases with stromal tumors and tumor like lesions of the prostate were observed. Some of them were followed up. Results Of the 16 cases, 6 presented stromal nodular hyperplasia, 3 were stromal sarcoma, 1 malignant phyllodes type tumor, 3 leiomyosarcoma, 1 fibrosarcoma, and one non Hodgkin′s lymphoma. Conclusions Nearly all the leiomyomas of the prostate diagnosed previously are, in fact, stromal nodular hyperplasia. The phyllodes type tumors are often confused with stromal sarcomas in needle biopsy specimens and cause difficulty in differential diagnosis. Diagnostic criteria of leiomyosarcoma, fibrosarcoma, non Hodgkin′s lymphoma of the prostate are the same as their counterparts in the soft tissue. Non epithelial malignant tumors in prostate are of poor prognosis.

目的 探讨前列腺非上皮性肿瘤的诊断和鉴别诊断并观察其预后。方法 收集临床及病理资料 ,应用HE、免疫组织化学LSAB法及电镜等方法 ,对 16例前列腺非上皮性肿瘤的临床和形态特点进行了观察 ,并进行了随访。结果  16例中诊断前列腺间质结节 6例 ,前列腺恶性分叶状肿瘤 1例 ,前列腺间质肉瘤 3例 ,前列腺平滑肌肉瘤 3例 ,纤维肉瘤 1例 ,前列腺非霍奇金恶性淋巴瘤 2例。结论 伴发于前列腺良性增生过去诊断为前列腺平滑肌瘤的病变实为前列腺的间质结节。在穿刺的标本中 ,前列腺叶状囊肉瘤易与前列腺间质肉瘤混淆 ,前列腺间质肉瘤以无特定结构的小梭形细胞为特点。前列腺平滑肌肉瘤、纤维肉瘤、前列腺非霍奇金恶性淋巴瘤与软组织同类肿瘤的诊断标准相同。前列腺非上皮性恶性肿瘤预后差

Objective To evaluate the expression of alpha-methylacyl-coenzyme-A racemase (AMACR,P504s) with immunohistochemical staining in diagnosis of prostate carcinoma. Methods A total of 133 specimens were taken from the patients (mean age,71 years),including 46 cases of prostate carcinoma (PCa) (1 case of stage A,19 cases of stage B,14 cases of stage C,12 cases of stage D;4 cases of gradeⅠ,14 cases of gradeⅡ,28 cases of grade Ⅲ),53 cases of benign prostate hyperplasia (BPH),13 cases of prostate intraepithelial tumor...

Objective To evaluate the expression of alpha-methylacyl-coenzyme-A racemase (AMACR,P504s) with immunohistochemical staining in diagnosis of prostate carcinoma. Methods A total of 133 specimens were taken from the patients (mean age,71 years),including 46 cases of prostate carcinoma (PCa) (1 case of stage A,19 cases of stage B,14 cases of stage C,12 cases of stage D;4 cases of gradeⅠ,14 cases of gradeⅡ,28 cases of grade Ⅲ),53 cases of benign prostate hyperplasia (BPH),13 cases of prostate intraepithelial tumor (PIN),9 cases of normal prostate,6 cases of prostatitis,3 cases of metastatic prostate cancer.Two sections of each specimen were made,with 1 stained by hematoxylin and eosin,and the other stained immunohistochemically by a rabbit monoclonal antibody to AMACR (P504s).AMACR staining expression was characterized as negative (score,1), weak (positive) (2), moderate (3) or strong (4). Results In 46 cases of PCa,AMACR staining expression was negative in 2 cases,weak in 1,moderate in 25 and strong in 18,with a mean staining intensity of 3.28 [95% confidence interval (CI), 3.07-3.50]. In 53 cases of BPH, the staining expression was negative in 47 cases, weak in 6, with a mean intensity of 1.11 (95% CI, 1.02-1.20).In 13 cases of PIN, the staining expression was negative in 12, weak in 1, with a mean intensity of 1.08 (95% CI, 0.91-1.24).The score of PCa group was significantly different from those of the latter 2 groups (P<0.001).All the specimens of other groups (normal prostate, prostatitis, metastatic prostate cancer,etc) had negative staining. Conclusions AMACR (P504s) has gerat value in diagnosis of PCa.

目的探讨α甲酰辅酶A消旋酶(AMACR,P504s)免疫组化染色在前列腺癌诊断中的价值。方法前列腺癌(PCa)标本46例(A期1例,B期19例,C期14例,D期12例;Ⅰ级4例,Ⅱ级14例,Ⅲ级28例),良性前列腺增生(BPH)53例,前列腺上皮内瘤(PIN)13例,正常前列腺9例,前列腺炎6例,膀胱癌转移前列腺3例,前列腺间质肉瘤、鳞癌、未分化癌各1例。平均年龄71岁。采用HE染色及P504s的兔单克隆抗体行免疫组化分析。P504s表达分为阴性(1分)、弱阳性(2分)、阳性(3分)、强阳性(4分)。结果46例PCa标本中P504s阴性2例、弱阳性1例、阳性25例、强阳性18例,平均染色浓度3.28分(95%可信区间CI3.07~3.50分);53例BPH标本中P504s阴性47例、弱阳性6例,平均染色浓度1.11分(95%CI1.02~1.20分);13例PIN标本中P504s阴性12例、弱阳性1例,平均染色浓度1.08分(95%CI0.91~1.24分)。PCa组与BPH、PIN组差异有统计学意义(P<0.001)。正常前列腺、前列腺炎、前列腺间质肉瘤、鳞癌、未分化癌、膀胱癌转移前...

目的探讨α甲酰辅酶A消旋酶(AMACR,P504s)免疫组化染色在前列腺癌诊断中的价值。方法前列腺癌(PCa)标本46例(A期1例,B期19例,C期14例,D期12例;Ⅰ级4例,Ⅱ级14例,Ⅲ级28例),良性前列腺增生(BPH)53例,前列腺上皮内瘤(PIN)13例,正常前列腺9例,前列腺炎6例,膀胱癌转移前列腺3例,前列腺间质肉瘤、鳞癌、未分化癌各1例。平均年龄71岁。采用HE染色及P504s的兔单克隆抗体行免疫组化分析。P504s表达分为阴性(1分)、弱阳性(2分)、阳性(3分)、强阳性(4分)。结果46例PCa标本中P504s阴性2例、弱阳性1例、阳性25例、强阳性18例,平均染色浓度3.28分(95%可信区间CI3.07~3.50分);53例BPH标本中P504s阴性47例、弱阳性6例,平均染色浓度1.11分(95%CI1.02~1.20分);13例PIN标本中P504s阴性12例、弱阳性1例,平均染色浓度1.08分(95%CI0.91~1.24分)。PCa组与BPH、PIN组差异有统计学意义(P<0.001)。正常前列腺、前列腺炎、前列腺间质肉瘤、鳞癌、未分化癌、膀胱癌转移前列腺标本P504s染色均为阴性。结论P504s检测诊断PCa有重要的参考价值。

 
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