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剂量-容积直方图
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     Rapid Compultation for Dose-Volume Histogram
     剂量体积直方图的快速计算
短句来源
     Dose volume histograms were performed for each target/technique combination.
     每个靶区和每种技术都经过剂量容积直方图计算。
短句来源
     Analysis of 3D dose distributions and dose volume histograms (DVH) was used to evaluate the dose and volume in tumor, parotids and spinal cord in the patients.
     对患者的肿瘤、腮腺和脊髓作三维剂量分布和剂量容积DVH直方图分析。
短句来源
     Then, a rational converging beam technic was adopted . (3) The 50% and 20% doses received by the lung were 18% and 49% by the dose volume histogram.
     (3)采用剂量容积百分比直方图,50%,20%肺最大受量体积分别为18%,49%。
短句来源
     A Development of the Conventional DVH ——Function Dose-volume Histograms
     剂量体积直方图的扩充——功能剂量体积直方图
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  dose-volume histogram
Influence of Treatment Technique on Dose-Volume Histogram and Normal Tissue Complication Probability for Small Bowel and Bladder
      
The aim of this paper is to examine the usefulness of the receiver operating characteristic (ROC) analysis using dose-volume histogram data to evaluate the conformity degree of a stereotactic treatment plan, as well as to propose a reference isodose.
      
Treatment outcomes and dose-volume histogram analysis of simultaneous integrated boost method for malignant gliomas using intens
      


Objective: To study the optimal treatment plan for small intracranial lesions(< 10cm3) in gamma knife radiosurgery. Methods:With different collimators(18mm,14mm,8mm),treatment plans for three small intracranial lesions were done with Leksell Gamma Plan .Dose volume histograms for both within the target volume and surrounding normal brain tissue of each plan was calculated using LGP5.12. The treatment parameters(HI and CI) for each plan were made.The comparison of dose distribution and dose homogeneity among...

Objective: To study the optimal treatment plan for small intracranial lesions(< 10cm3) in gamma knife radiosurgery. Methods:With different collimators(18mm,14mm,8mm),treatment plans for three small intracranial lesions were done with Leksell Gamma Plan .Dose volume histograms for both within the target volume and surrounding normal brain tissue of each plan was calculated using LGP5.12. The treatment parameters(HI and CI) for each plan were made.The comparison of dose distribution and dose homogeneity among different plans was done.Results: Between single-isocenter plan and multi-isocenters plan,the dose volume histogram showed different falling gradient above 50% isodose within the target volume,futhermore there are differences in the volume of normal brain irradiated in the less than 50% isodose region. The comparison of homogeneity indexes showed that multiple isocenter treatments were associated with a relative dose inhomogeneity within the target volume.Conclusion:Both dose-volume histogram and dose lack of homogeneity index demonstrate that treatment plan by single isocenter for small,nearly spherical volume is superior to that by other multi-isocenters treatment plans if the single isocenter conformed very well to the lesion contour. The use of multi-isocenters improved the conformality for irregular shaped lesions.Especially for both small,sphericall volume and irregular volume.the use of narrow beam collimators improved the target homogeneity and dose distribution of surrounding brain tissue.

目的 :探讨颅内小病灶伽玛刀治疗的最优化剂量方案。方法 :选取容积未超过10cm3 且周围无重要敏感结构的3例形状不同的颅内小病灶分别单一使用18、14、8mm的准直器进行治疗计划的设计。根据剂量参数进行均匀指数和适形指数的计算并绘出剂量容积直方图进行分析。结果 :不同准直器组合的剂量计划的参数显示 :对球形病灶单等中心计划的剂量均匀性和适形性最好且病灶周围正常脑组织接受等剂量曲线容积最小。对不规则病灶增加等中心数即增加不均匀性。结论 :对于单等中心即能实现良好适形性的颅内小病灶 ,应避免使用多等中心。对于不规则形状病灶以及邻近重要功能区的病灶 ,则应根据病灶形状、性质及周围邻近结构选择适当的准直器组合 ,以提高疗效。

The dose comformity and normal tissue isodose characteristics were compared by four stereotactic techniques of radiotherapy for two tumor target shapes. Methods Two test targets were constructed and calculated using a 3D treatment planning system after patients received CT simulation. The targets included a small regular tumor and a large irregular tumor. The stereotactic techniques were compared for each target: 1. Arc: 3 - 4 arcs as used in traditional linear radiotherapy. 2. Comformal therapy(3D): 6 fixed...

The dose comformity and normal tissue isodose characteristics were compared by four stereotactic techniques of radiotherapy for two tumor target shapes. Methods Two test targets were constructed and calculated using a 3D treatment planning system after patients received CT simulation. The targets included a small regular tumor and a large irregular tumor. The stereotactic techniques were compared for each target: 1. Arc: 3 - 4 arcs as used in traditional linear radiotherapy. 2. Comformal therapy(3D): 6 fixed noncoplanar fields. 3. Intensity modulation radiotherapy(IMRT) a: 5 coplanar beams and a multileaf collimator. 4. IMRTb: noncoplanar beams and a multileaf collimator. IMRT were calculated using inversely - planned system. Dose volume histograms were performed for each target/technique combination. Results For the small regular tumor, dose conformity and normal tissue isodose distributions were similar in all four techniques, and IMRTa was more favorable than others. For the large irregular tumor, dose conformity was most favorable in IMRTb, and high/low isodose of normal tissue distribution was more favorable than IMRTa. Conclusion The intensity- modulated technique may improve dose conformity and decrease the dose for the normal tissue in a high/low isodose region as compared with the ARC and 3D technique. IMRT delivery may increase the therapeutic efficacy in treating large and irregularly shaped targets that were stereotactically defined.

目的 对二种不同形状的肿瘤靶区设野计算,比较四种立体放射治疗技术的剂量适形特点和正常组织受照剂量。方法 患者经过CT模拟定位后,行三维治疗计划勾画和计算。二个靶区,一个小而规则的肿瘤和一个大而不规则的肿瘤。用四种立体放射治疗技术对二靶区进行计算和比较:1.旋转治疗(ARC):似传统的直线加速器的旋转治疗,用3~4个弧度;2.三维适形技术(3D):用6个非共面固定野治疗;3.调强治疗(IMRTa):用5个共面固定野和多叶光栅调强治疗;4.IMRTb:用6个非共面固定野和多叶光栅调强治疗。IMRT由反向治疗计划系统计算。每个靶区和每种技术都经过剂量容积直方图计算。结果 对小而规则的肿瘤,四种技术的剂量适形度和正常组织的等剂量分布基本相似,IMRTa相对更加出色。对大而不规则的肿瘤,在靶区剂量适形度上IMRTb表现最好;在正常组织的高/低剂量分布上IMRTa最好。结论 与ARC和3D相比,调强技术能提高靶区剂量的适形度和减少正常组织的高/低受照剂量和范围,用立体放射技术治疗大而不规则的肿瘤靶区,调强技术可以提...

目的 对二种不同形状的肿瘤靶区设野计算,比较四种立体放射治疗技术的剂量适形特点和正常组织受照剂量。方法 患者经过CT模拟定位后,行三维治疗计划勾画和计算。二个靶区,一个小而规则的肿瘤和一个大而不规则的肿瘤。用四种立体放射治疗技术对二靶区进行计算和比较:1.旋转治疗(ARC):似传统的直线加速器的旋转治疗,用3~4个弧度;2.三维适形技术(3D):用6个非共面固定野治疗;3.调强治疗(IMRTa):用5个共面固定野和多叶光栅调强治疗;4.IMRTb:用6个非共面固定野和多叶光栅调强治疗。IMRT由反向治疗计划系统计算。每个靶区和每种技术都经过剂量容积直方图计算。结果 对小而规则的肿瘤,四种技术的剂量适形度和正常组织的等剂量分布基本相似,IMRTa相对更加出色。对大而不规则的肿瘤,在靶区剂量适形度上IMRTb表现最好;在正常组织的高/低剂量分布上IMRTa最好。结论 与ARC和3D相比,调强技术能提高靶区剂量的适形度和减少正常组织的高/低受照剂量和范围,用立体放射技术治疗大而不规则的肿瘤靶区,调强技术可以提高治疗率。

Objective Developing a motion-simulating model for various radiation treatment plans to study the effects of organ motion using Monte Carlo simulations. Methods This paper presents a 4D digital anatomical model for studying effects of organ motion on radiation treatment and delivery. An existing 3D VIP-Man (visible photographic man) model has been reconstructed using sampled control points for organs and non-uniform rational B-splines (NURBS) method. Transformation on those control points, using the respiratory...

Objective Developing a motion-simulating model for various radiation treatment plans to study the effects of organ motion using Monte Carlo simulations. Methods This paper presents a 4D digital anatomical model for studying effects of organ motion on radiation treatment and delivery. An existing 3D VIP-Man (visible photographic man) model has been reconstructed using sampled control points for organs and non-uniform rational B-splines (NURBS) method. Transformation on those control points, using the respiratory motion data obtained clinically, can be used to get the 4D partial-body anatomical model by time-dependent equations. EGS4 (electron gamma shower, version 4) code is used for Monte Carlo calculations. To test the model proposed, a simulation study of a lung lesion was created to study the impact of organ motion on delivered radiation dose. Results In this simulation study, the lesion dose could differ as much as 40% for different respiratory phases in the simulation study. Conclusion This preliminary study demonstrates the potential of 4D digital anatomical model utilizing Monte Carlo code for 4D dose calculations.

目的开发一种可以用于蒙特卡罗模拟的四维动态运动模型来研究不同放射治疗计划中器官运动造成的影响。方法本文阐述了一个用在放射治疗计划上来研究器官运动影响的四维数字化人体模型。该模型通过对器官控制点的采样和使用非均匀有理B样条方法,对现存的三维VIP-Man(visiblephotographicman)模型利用临床中得到的呼吸运动数据进行器官控制点的时间,空间变换,进而得到四维的数字化人体解剖模型。一种蒙特卡罗代码,EGS4(electrongammashower,version4),被用于对该四维VIP-Man模型进行放疗模拟。出于测试模型目的,我们模拟了四维VIP-Man左肺部产生一肿瘤,通过传统三维四束对穿(前,后,左,右)来模拟计算呼吸运动对肿瘤剂量分配的影响。结果在本次模拟研究中,从不同呼吸相位产生的剂量的差别可达40%。目标剂量容积直方图明显存在区别。结论初步的研究证明了四维数字人体模型用于蒙特卡罗模拟计算中的潜能。

 
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