Accession number HSU20428 was given by NCBIgenebank in 1995, and was named by Gene Nomenclature Committee as ST14 (suppression of tumorigenicity 14) in 1998. The data from human genome project (HOP) shows that SNC19/ST14 gene contains 19 exons and 18 introns that span 50420 bp.
p16 gene is located on chromsome 9p21. The total length of cDNA is 8. 5 kb, consists of three exons and two introns. The exon 1 is 126bp,the exon 2 is 307bp and the exon 3 is 11bp. p16 gene encodes the protein of 16KD, consists of 156 amino acid.
Its gene, CDH1, is located in region 22.1 on the long arm of chromosome 16, including 16 exons and 15 introns, encoding a 120-kDa transmembrane calcium-dependent glycoprotein, with a shorter soluble proteolytic product of 80 kDa.
Any mutation in the porypyrimidine (py) tract and the branch point consensus sequence of introns that affected splicing did so by interfering with efficient spliceosome assembly and splicing of pre - mRNAs.
内含子的嘧啶富集区[the polypyrimidine(py)tract]和支点一致序列(the branch point consensus sequence)中的任何突变都将通过干扰剪接体组装效率和mRNA前体(premRNA)的剪接直接影响剪接过程。
The result indicated that the sequence was 1,813 bp (BamHI and SacI were introduced at the 5' and 3' end) including 7 extrons and 6 introns, coding 238 amino acids.
Studies on the statistical characteristics of EID show that there were 103, 848 genes, 478,484 introns, and 582,332 exons, with an average of 4.61 introns and 5.61 exons per gene.
Results of the statistical analysis on the data from nine model species showed that in eukaryotes, higher species do not necessarily have more introns or exons in a gene than lower species.