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慢性感染     
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  chronic infection
     Molecular basis for the apoptosis of CD_4~+ T cells induced by chronic infection of Schistosoma japonicum
     日本血吸虫慢性感染致CD_4~+ T细胞凋亡的分子基础
短句来源
     The results indicated that 911 inhibited both acute and chronic infection of HIV 1 to MT 4 and H 9 cells with its half effect concentration (EC 50 ) at [HT5,5”] 4.44 mg·L 1 and 0.32mg·L 1 respectively in vitro.
     结果发现 911可明显抑制HIV- 1对 MT4 细胞的急性感染和 H9细胞的慢性感染 ,其半数有效浓度 ( EC50 )分别为 4 .4 4 mg· L-1和 0 .32mg· L-1;
短句来源
     Chronic infection of hepatitis B virus (HBV) is the main pathogenic factor for development of hepatocellular carcinoma (HCC).
     乙型肝炎病毒(hepatitis B virus,HBV)慢性感染,是引发肝硬变(liver cirrhosis,LC)和肝细胞癌(hepatocellular carcinoma,HCC)的主要原因。
短句来源
     87% with NP30 in the group of chronic infection which was comparable to 86% with GAA but lower than that of 98% with SEA.
     在慢性感染时NP30抗体的检出率为87%,与GAA(86%)的无差别,但低于SEA(98%)的。
短句来源
     Conclusion Chronic infection of HCV up-regulates the mRNA expression of IL-8, I-309, MIG and TARC in PBMC.
     结论HCV慢性感染能诱导外周血单个核细胞表达IL8、I309、MIG和TARC。
短句来源
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  chronic infections
     Chronic infections with hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most important risk factors for the development of HCC in humans.
     乙型肝炎病毒(hepatitis B virus,HBV)和丙型肝炎病毒(hepatitis C virus,HCV)的慢性感染是人HCC发生的最重要的危险因素。
短句来源
     The prevalent rate of hypertention(HT),coronary heart disease(CHD),diabetic retinopathy(DR),diabetic nephropathy(DN),diabetic neuropathy(DNP),diabetic chronic infections and diabetic lipidemia were 19.7%,9.4%, 14.15% ,16.03%,24.5%,20.25%,and 42.5% respectively.
     HT、CHD、DR、DN、DNP和慢性感染、糖尿病脂血症的患病率分别为 19.7%、9.4%、14.15 %、16 .0 3%、2 4.5 %、2 0 .75 %和 42 .5 % ;
短句来源
     CONCLUSION: There is apoptosis in PBMC of the HBV chronic infections.
     结论:HBV慢性感染患者PBMC存在凋亡,其凋亡率较健康组明显增加.
短句来源
     Recently, growing evidences have been presented to support the association between the chronic infections and CD4+CD25+ regulatory T cells.
     对曼氏血吸虫慢性感染的研究已经开始涉及CD4~+CD25~+调节性T细胞的免疫调节作用,但迄今为止,在日本血吸虫感染的研究中尚无有关报道。
短句来源
     Epidemiological study on four hepatitis related viruses associated with chronic infections
     4种引起慢性感染的肝炎相关病毒的流行病学研究
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  chronically infected
     After 15 hours, the number of EOS increased significantly in the skin of chronically infected mice.
     攻击感染15b后,慢性感染鼠皮肤内的嗜酸粒细胞(EOS)较初次感染鼠明显增加.
短句来源
     AGB also inhibited the syncytium formation between the normal C8166 celland HIV-1 chronically infected H9 cell in co-culture.
     阻断HIV-1慢性感染H9细胞与正常C8166细胞间融合的作用。
短句来源
     Three-color flow cytometry was performed to study intracellular protein levels of IFN-γ、IL-4 of CD4 + cell. Results In the CD4 + cell of chronically infected mice, IL-4 was remarkably increase d at both transcription and protein expression levels (P<0.05), especially a fter stimulation with soluble egg antigen (P<0.01);
     结果 日本血吸虫慢性感染小鼠CD4+细胞中IL 4的转录及蛋白表达水平均明显高于正常小鼠 (P <0 .0 5) ,尤其以可溶性虫卵抗原刺激后最为显著 (P <0 .0 1) ;
短句来源
     Conclusion In chronically infected PDH model, virion and DHBV specific protein synthesis were inhibited by rDuIFNγ in a concentration dependent manner.
     结论 DuIFN γ在体外DHBV慢性感染的PDH模型中可抑制病毒复制
短句来源
     At the peak time of viremia,the positive cells accounted for more than 95% of the total in chronically infected ducks,whereas 24%~58% in acutely infected ones.
     急性感染组病毒复制高峰期阳性细胞仅为 2 4 %~ 5 8% ,慢性感染组可 >95 % ;
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  chronic infectious
     The Etiological Diagnosis of Chronic Infectious Meningitis
     慢性感染脑膜炎的病因诊断
短句来源
     The Clinical Evaluation of Ion Introduction Remedy in Chronic Infectious Root Canal Treatment
     离子导入法应用于慢性感染根管治疗的临床疗效观察
短句来源
     The anemia fo chronic disease(ACD) is one of the most common sy ndromes, which was found in the patients with chronic infectious,inflammatory,an d neoplastic disorders.
     慢性感染、炎症及肿瘤性疾病所伴有的贫血通常称为慢性病性贫血(ACD),是临床最常见的综合征之一.
短句来源
     Exclusive criteria:lesion in great vessels,diseases in connective tissues,malfunction of liver and kidney,acute and chronic infectious patients.
     排除标准:排除大血管病变,结缔组织疾病,无肝肾功能不全,无急性和慢性感染患者。
短句来源
     Cytomegalovirus(CMV) is an important pathogen of congenital and postnatal infections in children,which causes a series of acute and chronic infectious diseases and nervous system sequelaes.
     巨细胞病毒(CMV)是儿童先天性感染和生后获得性感染的重要病原,可引起多种急、慢性感染和神经系统迟发后遗症。
短句来源

 

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      chronic infection
    Special attention should be given to treatment of foci of chronic infection and of the carrier state of certain microorganisms.
          
    An acute to chronic infection progressed in mice infected with this mixture of anaerobic bacteria, whereas no infection resulted when either organism was injected alone.
          
    The results suggest thatFusobacterium, which contains the more potent endotoxin, predisposes the animals to chronic infection withBacteroides which predominates during the chronic phase.
          
    The former were considered to be acute hepatitis B infections and the latter chronic carriers superinfected with another virus or acute exacerbation of chronic infection.
          
    The postulated risk should mainly be attributed to misdiagnosis of cases of superinfection of chronic carriers or acute exacerbation of chronic infection.
          
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      chronic infections
    The data are discussed and compared with the other chronic infections of the central nervous system.
          
    Patients with acute urinary tract infections given 400 mg bacampicillin and patients with chronic infections given double that dosage showed equally good results.
          
    The resistant organisms emerged particularly in certain clinical settings where large numbers of organisms frequently causing chronic infections are present and/or in loci where quinolone concentrations may not be optimal.
          
    All these studies indicate that FQs exert immunomodulatory activities in particular in latent or chronic infections.
          
    Sharing routes of transmission, hepatitis C virus (HCV) and human immunodeficiency virus type 1 (HIV-1) are often harbored in the same host, establishing chronic infections characterized by high serum viral loads.
          
    更多          
      chronically infected
    A cell line chronically infected with the 6/94 virus has been maintained for more than 100 passagesin vitro.
          
    Close correlation between hepatitis C virus serology and polymerase chain reaction in chronically infected patients
          
    Surveillance with abdominal ultrasound of chronically infected cirrhotic patients is the only realistic approach for hepatocellular carcinoma (HCC) treatment improvement, because it allows for detection of small, better treatable tumors.
          
    Approximately four million Americans have been exposed to the hepatitis C virus (HCV) and are anti-HCV positive; almost three million are chronically infected and HCV RNA positive.
          
    In 2006, five such candidate drugs have entered phase II clinical trials in patients chronically infected with hepatitis C, including small molecule inhibitors of the HCV NS3 serine protease and NS5B RNA-dependent RNA polymerase.
          
    更多          
      chronic infectious
    burgdorferi from patients with chronic Lyme disease certainly defines the nature of the illness and establishes that it is of chronic infectious etiology.
          
    Accumulation of neutrophils occurs in chronic infectious rhinosinusitis, foreign body reactions, and immunodeficiencies.
          
    Relevant inflammatory diseases include general and chronic infectious diseases as well as localized acute or chronic infections of the male genitourinary tract.
          
    Open biopsy was necessary for diagnosis, since the radiological abnormalities are consistent with other chronic infectious diseases.
          
    A decrease in lymphocyte signal-transduction molecules, described in cancer patients and patients with chronic infectious diseases, has been proposed as a possible mechanism leading to an impaired immune response in cancer patients.
          
    更多          


    Three cases of spino-cerebellar degeneration were reported. Case 1 had been observed for ten years. The main symptoms were ataxia, accompanied by ophthalmoplegia and hypertonia of extrapyramidal type. Autopsy demonstrated lesions in the oculomotor nuclei and substantia nigra, suggesting that the ataxia might be related to Parkinsonism. Case 2 presented a typical clnical picure of cerebellar type of hereditary ataxia, but there was also demyelination in the spinal posterion funiculus. Case 3 was clinically typical...

    Three cases of spino-cerebellar degeneration were reported. Case 1 had been observed for ten years. The main symptoms were ataxia, accompanied by ophthalmoplegia and hypertonia of extrapyramidal type. Autopsy demonstrated lesions in the oculomotor nuclei and substantia nigra, suggesting that the ataxia might be related to Parkinsonism. Case 2 presented a typical clnical picure of cerebellar type of hereditary ataxia, but there was also demyelination in the spinal posterion funiculus. Case 3 was clinically typical of Friedreich's ataxia, but degenerative lesions in the cerebellum and lumbo-sacral nerve roots were shown, suggesting that the symptoms were related to Charcot-Marie-Tooth type of myotrophy. Myocardiac degeneration was also present in this patient. The presence of lymphocytic infiltration in the lesion suggested that there was chronic inflammation and/or immunological reaction.

    本文报告3例脊髓小脑变性。例1临床观察10年,主要表现为共济失调,伴眼肌麻痹和锥体外型肌张力过高,尸检证实中脑动眼神经核及黑质有病变,提示共济失调症与巴金森氏症有密切关系。例2临床上为典型的遗传性小脑共济失调,病理上脊髓后索有脱鞘病变。例3临床上为典型Friedreich型共济失调;病理上亦见小脑、腰骶神经病变,提示与Charcot-Marje-Tooth神经型肌萎缩有关,病变部位见到淋巴细胞浸润或可提示慢性感染和(或)免疫反应。

    Chronic HBV carriers tend to cluster in families.The serum HBV markers,anti-HBcIgM,HBV DNA and HBV DNA polymerase of 170 residents in families withhepatocellular carcinoma(HCC)were studied.The frequencies of positive serum anti-HBc,HBeAg,anti-HBcIgM,HBV DNA and DNA polymerase were 85.3%,21.8%,3.5% 17.6% and 18.9% respectively.These were similar to the results of HCC group(96.5%,22.8%,2.6%,11.4% and 13% respectively).The prevalence,of hepatitis andhepatoma was the highest in the families of maternal relatives...

    Chronic HBV carriers tend to cluster in families.The serum HBV markers,anti-HBcIgM,HBV DNA and HBV DNA polymerase of 170 residents in families withhepatocellular carcinoma(HCC)were studied.The frequencies of positive serum anti-HBc,HBeAg,anti-HBcIgM,HBV DNA and DNA polymerase were 85.3%,21.8%,3.5% 17.6% and 18.9% respectively.These were similar to the results of HCC group(96.5%,22.8%,2.6%,11.4% and 13% respectively).The prevalence,of hepatitis andhepatoma was the highest in the families of maternal relatives with hepatoma.It maysupport that transmission of HBV from carrier mothers to their children in earlyinfancy is the main way causing persistent infection.Our data showed that the longerhistory of HBV infection,the lower frequency of free HBV DNA in serum.Thefrequency of positive serum HBV DNA in cases with history of hepatitis over 5 yrsis much lower than that of less than 5 yrs.It suggests that HBV DNA may integratin the host cell genome during the persistent HBV infection.These results show thatepeople in families with HCC patients would have higher risk of developing HCC.

    慢性乙肝携带具有积聚倾向,我们对170例具有肝癌家属史的本地居民进行了血清HBV 感染标志,Anti-HBc IgM,HBV DNA 和 HBV DNA 聚合酶检测,其检测结果 Anti-HBc、HBeAg、Anti-HBc IgM、HBV DNA、HBV DNA 聚合酶阳性率分别为85.3%、21.8%、3.5%、17.6%和18.9%,近似于肝癌组阳性率96.5%,22.8%,2.6%,11.4%和13%。在母系肝癌家庭成员中肝炎发生率和肝癌阳性率最高,支持母系垂直传播是构成 HBV 感染的重要途径。肝炎病史越长,血清中游离的 HBV 抗原阳性率越低,5年以上肝炎病史者血清 HBV DNA 阳性率比5年以下的肝炎患者或无肝炎病史者均明显为低,提示 HBV 长期感染后病毒基因可能整合入肝细胞内并发生质的变化。综合所测结果认为肝癌患者家庭成员中的 HBV 慢性感染者是发生肝癌的危险人群。

    From June 1983 to July 1985 11 Cases of infectious wounds of the extremities were treated with transplantation of microvascular skin flaps or musculocutaneous flaps. Among them 9 Cases were Chronic infectious wounds and 2 new infectious wounds; 10 were Successfully cured and lfailed Satisfactory results had been obtained by using this method for the repair of infectious wounds.

    本文介绍了采用带血管的皮瓣、肌皮瓣移植的方法治疗四肢感染创面11例。包括慢性感染溃疡、慢性骨髓炎并瘘管形成9例;新鲜创面感染2例。仅1例因静脉受骨残端压迫致回流障碍失败外,余均获得成功。并总结了成功的经验与失败的教训。

     
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