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骨髓
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  bone marrow
    The Effect of Proliferation,Differentiation to Osteoblast and Expression of Cbfa1 of SD Rat'S Bone Marrow Stromal Cells in Vitro by Morinda Officinalis How
    巴戟天对大鼠骨髓基质细胞增殖、成骨分化及Cbfα1基因表达的影响
短句来源
    Effects of Papaver Pollen on the Frequency of Micronuclei of Bone Marrow Erythrocytes in Mice
    罂粟花粉对小鼠骨髓微核细胞率的影响
短句来源
    Effect of Aluminum Potassium Sulfate on Micronucleus of Bone Marrow Polychromatic Erythrocyte in Mice
    明矾对小鼠骨髓多染红细胞微核的影响
短句来源
    Effects of Lycium barbarum polysaccharides on proliferation and differentiation of hematopoietic stem cells and progenitors of granulocytes and macrophages in mouse bone marrow
    枸杞多糖对小鼠骨髓造血干细胞、粒单系祖细胞增殖分化的影响
短句来源
    The Influence of 5-Fluorouracil on Micronucleus Rate of Bone Marrow Cells and Embryonal Liver Blood Cells in Pregnant Mice
    氟脲嘧啶对孕鼠骨髓和胎肝血细胞微核率的影响
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  marrow
    Proliferation, Differentiation and Apoptosis Molecular Biology Study on the Adjust Mechanism of SD Rat's Marrow Stromal Cell by Sthenia Skeleton Herbs Mixture in Vitro
    补骨合剂对大鼠骨髓基质细胞增殖、分化及凋亡的分子调控机理研究
短句来源
    The Effect of Proliferation,Differentiation to Osteoblast and Expression of Cbfa1 of SD Rat'S Bone Marrow Stromal Cells in Vitro by Morinda Officinalis How
    巴戟天对大鼠骨髓基质细胞增殖、成骨分化及Cbfα1基因表达的影响
短句来源
    Effects of Papaver Pollen on the Frequency of Micronuclei of Bone Marrow Erythrocytes in Mice
    罂粟花粉对小鼠骨髓微核细胞率的影响
短句来源
    Effect of Aluminum Potassium Sulfate on Micronucleus of Bone Marrow Polychromatic Erythrocyte in Mice
    明矾对小鼠骨髓多染红细胞微核的影响
短句来源
    Effects of Lycium barbarum polysaccharides on proliferation and differentiation of hematopoietic stem cells and progenitors of granulocytes and macrophages in mouse bone marrow
    枸杞多糖对小鼠骨髓造血干细胞、粒单系祖细胞增殖分化的影响
短句来源
更多       
  bone morrow
    Femur bone morrow slides were made by Wright's staining and qualitative and quantitative observation on bone marrow image.
    采用姬姆萨-瑞氏染色法制作股骨骨髓涂片,对骨髓象进行定性、定量观察;
短句来源
  “骨髓”译为未确定词的双语例句
    Protective effects of Panax notoginsenoside Rb_1 and Rg_1 preconditioning on angiotensin Ⅱ induced hypertrophied neonatal rat myocytes against hypoxia-reoxygenation injury and effect of Panax notoginsenoside Rg_1 on thansduction from BMSCs to cardi
    参三七皂甙Rb_1、Rg_1预适应对AngⅡ致肥厚心肌细胞H/R损伤的保护作用及Rg_1对5-AZ诱导大鼠骨髓基质细胞向心肌细胞转化的影响
短句来源
    EFFECT OF ELECTROACUPUNCTURE ON PERIPHERAL LEUKOCYTE COUNT, CFU-GM FREQUENCY AND PLASMA cGMP LEVEL IN RAT
    电针刺激对大鼠外周血白细胞、骨髓CFU—GM及血浆cGMP含量的影响
短句来源
    EFFECTS OF FETAL LIVER CELL-FREE LIQUID ON THE HEMATOPOIETIC CELLS IN MURINEMARROW AFTER LARGE DOSE CHEMOTHERAPY
    无细胞胎肝液对大剂量化疗后小鼠骨髓造血细胞的影响
短句来源
    Methods Forty BALB/c mice were randomly allocated to 4 groups: a normal control group, a model group, cyclosporine A (CSA) group and FZYYG group.
    方法:BALB/c小鼠40只随机分为正常组、模型对照组、环孢霉素A对照组、扶正养营颗粒实验组,记数外周血象、骨髓有核细胞,测定骨髓造血组织容量及bcl-2表达。
短句来源
    Results:Rat mesenchymal stem cells could be separated and amplified in vitro.
    结果:大鼠骨髓间充质干细胞可通过贴壁法成功分离并可在体外大量扩增。
短句来源
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为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  bone marrow
The effects of hematopoietic stem/progenitor cells (HSPCs) expanded in the two step coculture with human bone marrow mesenchymal stem cells (hMSCs) on the hematopoietic reconstruction of irradiated NOD/SCID mice were studied.
      
Effects of malondialdehyde on growth and proliferation of human bone marrow mesenchymal stem cells in vitro
      
Malondialdehyde (MDA) is a well known inducer of carbonyl stress in a variety of human cells, however, its effects on human bone marrow mesenchymal stem cells (hMSCs) have not been documented.
      
In this study, murine mononuclear cells (MNCs) were isolated from bone marrow and cultured in suspension, and then Lin-CD117+ HSCs were isolated by immunomagnetic beads.
      
Cytokines mRNA in bone marrow-derived dendritic cells in asthmatic mouse
      
更多          
  marrow
The effects of hematopoietic stem/progenitor cells (HSPCs) expanded in the two step coculture with human bone marrow mesenchymal stem cells (hMSCs) on the hematopoietic reconstruction of irradiated NOD/SCID mice were studied.
      
Effects of malondialdehyde on growth and proliferation of human bone marrow mesenchymal stem cells in vitro
      
Malondialdehyde (MDA) is a well known inducer of carbonyl stress in a variety of human cells, however, its effects on human bone marrow mesenchymal stem cells (hMSCs) have not been documented.
      
In this study, murine mononuclear cells (MNCs) were isolated from bone marrow and cultured in suspension, and then Lin-CD117+ HSCs were isolated by immunomagnetic beads.
      
Cytokines mRNA in bone marrow-derived dendritic cells in asthmatic mouse
      
更多          
  bone morrow
Immunotherapy in the patients whose bone morrow was positive for MRD post-AHSCT may intensify remission and reduce relapse rates.
      
Effect of homoharringtonine on bone morrow CD34+CD7+ cells in chronic granulocytic leukemia
      
Increased sensitivity and specificity of flow cytometry and polymerase chain reaction techniques enable us to detect few CLL cells in peripheral blood and bone morrow.
      
Expression of CD28 and CTLA4 on T cells in bone morrow of immune-mediated aplastic anemia mice
      
A case is presented in which a grossly abnormal distribution of bone morrow following failed hip replacement would have led to the false diagnosis of osteomyelitis.
      
更多          


The antifertility effect of gossypol was discovered and confirmed by Chinese Scientific workers during therecent years through experiments onanimals and clinical studies.However,It's toxicity to animals and the develop-ment of side effects in some of thesubjects following gossypol administra-tion have also been reported.In orderto analyze the cause and effect rela-tionship between the toxicity and thenature of metabolism of gossypol,wehave conducted experiments designedto obtain information concerning themetabolic...

The antifertility effect of gossypol was discovered and confirmed by Chinese Scientific workers during therecent years through experiments onanimals and clinical studies.However,It's toxicity to animals and the develop-ment of side effects in some of thesubjects following gossypol administra-tion have also been reported.In orderto analyze the cause and effect rela-tionship between the toxicity and thenature of metabolism of gossypol,wehave conducted experiments designedto obtain information concerning themetabolic fate of gossypol in rats fol-lowing the oral administration of ~(14)C-gossypol acetic acid.Wistar male rats selected for uniformity of weight (105—200g body weight) were placed in individual metaboliccages that were designed to controlexperimental conditions.A single oraldose (94μci/35mg) of radioactive gos-sypol (sp.act.2.665μci/mg) was givento each rat in one group of experi-ments,and in another group the ratswere given labeled gossypol at thedosage of 4.5μci/5mg/day for 2—3 weeksconsecutively.The rats were anesthetized and frozen in acetone cooled to-78℃ with dry ice after varying intervals of time.Whole body andmicro-autoradiography of various or-gan tissues were performed according tothe methods described elsewhere.Ob-servations on the absorption,distribu-tion,accumulation and elimination of~(14)C-gossypol in the rat body as wellas cytopathological examination on theH.E.stained histological sections werecarried out.(1) The whole-body autoradio-graphs demonstrated that the radioac-tivity was located mainly over thegastro-intestinal tract and liver,andthe contents of different parts of the alimentary canal had the highest acti-vity 1-2 days following a single oraldose of ~(14)C-labeled gossypol.At thefourth day,there was a general increasein the activity in all tissues,and theradioactivity in the main visceral organswere rapidly reached to their highestlevel by the 9th day.Strong accumu-lation could be observed in the liver,spleen,kidney,adrenal,pancreas,mu-scle,lymph node,thymus,pitutary,testis and salivary gland in the 9th day autoradiograph.14 days after the administration,the radioactivity in alltissues and organs were markedly de-creased,Only in bones and lymphnodes still contained high activities.Most of the tissues had no detectableor having very low activity 19 daysafter the oral dosing,indicated that nolong term accumulation of gossypolretained in the visceras.(2) The pattern of absorption anddistribution of radioactivity in the bodyof rats that on continuous administra-tion of ~(14)C-gossypol (4.5μci/5mg/day)was basically similar to the rats thatreceived a single oral dose.In both dosage cases,the alimentary canaland liver had the highest activity,followed by the spleen,lymph nodes,heart,kidney,adrenal,bone marrow,salivary gland,thymus,muscle,testis,epididymis,accessory sex glands,pan-creas,lung and urinary bladder inwhich decreased their radioactivitiesin order.Gossypol was usually unde-tectable in the brain and spinal cordor having the lowest activity only,evidently there was blood-brain barrier that protected the brain against passage of gossypol.(3) The organs concerned withelimination of gossypol,spleen,lymphnode,thymus,bone marrow as well asthe reticulo-endothelial cells of variousvisceral organs (i.e.Kupffer cells ofliver,dust and septal cells of lung,lymphocytes,plasma cells and macro-phages in different tissues) showed highconcentrations of radioactivity,sugges-ted that the reticulo-endothelial systemmight play a part in the detoxicationof gossypol in the body.(4) Cytological examination reve-aled that,with the exception of thetestis,no pathological changes weredetectable in the organs and tissuessuch as liver,spleen,heart,kidney,lung,pancreas and bone marrow.Thefact that the testis is the only organthat is damaged at low dosage of gos-sypol and that the radioactivity in thetestis is lower than that in the aboveorgans indicates that the selective orhigher susceptibility of the testis togossypol is not due to concentration ofgossypol in the testis,but to a highervulnerabilit sensitivity of the testis to the drug. (5) The results revealed that there was rather high radioactivity in the endocrine organs concerned with re- production and water and salts metabo- lism (i.e.adrenal gland,pituitary andthe Leydig cells of interstitial tissuesof testis),and a significant but lowamounts of radioactivity in the nucleiof hypothalamus as well as the medianeminence,suggests the possibility thatgossypol might effect in some degreeon the above endocrine hormone secre-tions and on the autonomic nervouscenter as well.(6) The possible cause and effectcorrelation between the clinical sym-ptoms (i.e.The transient weakness,SGPT and ECG changes,hypokalemicand thirsty etc.) and gossypol adminis-tration in connection with the distribu-tion of ~(14)C-gossypol in high amountsin the corresponding tissues and organssuch as skeletal muscle,liver,heart,kidney and salivary gland in this reportwas discussed.

以~(14)C 标记的醋酸棉酚喂饲成年雄性大鼠,一次口服组的剂量为94微居里/35毫克;累加服药组为4.5微居里/日。分别于服药后不同时期取材制成整体或组织放射自显片。追踪标记棉酚在体内各脏器和组织中的吸收,分布和累积的定位变化动态。相应的组织切片用H、E 染色,作细胞病理学观察。结果摘述如下:1.一次口服标记棉酚后1—2天,标记物主要分布于胃、肠道和肝脏中。4—9天后,心、脾、肺、肾、胰、睾丸、附睾、附属性腺、肾上腺、垂体、胸腺、唾腺、骨髓、淋巴结和肌肉等脏器组织中的活性均迅速达到各自的高峰水平。以后标记物逐渐扩布至全身。14天后,活性明显下降。19天后,活性已不易追踪。未见有长期定位的累积现象。累加服药组的吸收和分布状态与一次服药组基本相同。2.定位于各脏器组织中的标记物活性强度以消化道为最高,其次为肝脏。以下的大体顺序为:脾、淋巴结>心、肾、垂体、肾上腺、骨髓>唾腺、胸腺、肌肉、睾丸、附睾、附属性腺、胰、肺>血液> 膀胱>脑及骨髓。骨质在后期活性略有升高。脑和脊髓的活性反应微弱,可能与血脑屏障的保护性作用有关。3.脾脏、淋巴结、胸腺、骨髓和各脏器中的网状内...

以~(14)C 标记的醋酸棉酚喂饲成年雄性大鼠,一次口服组的剂量为94微居里/35毫克;累加服药组为4.5微居里/日。分别于服药后不同时期取材制成整体或组织放射自显片。追踪标记棉酚在体内各脏器和组织中的吸收,分布和累积的定位变化动态。相应的组织切片用H、E 染色,作细胞病理学观察。结果摘述如下:1.一次口服标记棉酚后1—2天,标记物主要分布于胃、肠道和肝脏中。4—9天后,心、脾、肺、肾、胰、睾丸、附睾、附属性腺、肾上腺、垂体、胸腺、唾腺、骨髓、淋巴结和肌肉等脏器组织中的活性均迅速达到各自的高峰水平。以后标记物逐渐扩布至全身。14天后,活性明显下降。19天后,活性已不易追踪。未见有长期定位的累积现象。累加服药组的吸收和分布状态与一次服药组基本相同。2.定位于各脏器组织中的标记物活性强度以消化道为最高,其次为肝脏。以下的大体顺序为:脾、淋巴结>心、肾、垂体、肾上腺、骨髓>唾腺、胸腺、肌肉、睾丸、附睾、附属性腺、胰、肺>血液> 膀胱>脑及骨髓。骨质在后期活性略有升高。脑和脊髓的活性反应微弱,可能与血脑屏障的保护性作用有关。3.脾脏、淋巴结、胸腺、骨髓和各脏器中的网状内皮系细胞(枯否氏细胞、尘细胞、淋巴细胞、浆细胞、巨噬细胞等)均呈现高强度的放射活性。表明网状内皮系统可能参与清除棉酚的解毒过程。4.实验中出现较高活性分布的心、肝、脾、肾、肺、胰、骨髓等主要脏器组织均未见有细胞病理改变,而处于中等活性水平的睾丸曲细精管则出现明显的细胞损伤。表明生精上皮细胞对棉酚的敏感性较其他脏器组织为高。毒性反应与剂量水平在一定范围内似无正比相关,而与细胞的敏感性和耐受性的高低则有密切关系。5.与生殖及水盐代谢有关的内分泌腺:肾上腺、垂体和睾丸间质细胞均有较高的放射活性。丘脑下部有关核团及正中隆突亦有微弱的活性定位。提示了棉酚在某种条件下对上述内分泌激素分泌及植物性神经中枢产生影响的可能性。6.本报导联系临床上出现的口干、乏力及过渡性肝功能和心电图异常等毒性症状与相应脏器(唾腺、肌肉、肝及心脏)中标记棉酚活性分布的状态及其间的可能相关予以讨论。

In this study one group of experimental mice received a single doseof 850 or 900 rads ~(60)Co γ-ray of whole body irradiation to induce acuteradiation sickness, then they were treated with thymosin F_5 preparedfrom calf thymus; in an other group the mice had been treated withthymosin F_5 and then exposed to the same dose of ~(60)Co irradiation.The therapeutic and preventive effects of thymosin F_5 were observed. The results of this study indicated that thymosin F_5 had some effecton increasing the number of...

In this study one group of experimental mice received a single doseof 850 or 900 rads ~(60)Co γ-ray of whole body irradiation to induce acuteradiation sickness, then they were treated with thymosin F_5 preparedfrom calf thymus; in an other group the mice had been treated withthymosin F_5 and then exposed to the same dose of ~(60)Co irradiation.The therapeutic and preventive effects of thymosin F_5 were observed. The results of this study indicated that thymosin F_5 had some effecton increasing the number of survival experimental animal about 35-62.2% in 30-day limit compared with control group. The thymus, spleenand blood pictures of the animal survived were examined .It was foundthat the weight of thymus and bone marrow nucleated cell counts werebigher than those in control group (P<0.01) .The bone marrow stem cellassay was also observed. In vitro experiment thymosin F_5 was addedto the culture medium, and in vivo experiment thymosin F_5 injectedinto the irradiated mice, the colonies of stem cells in both experimentswere markedly increased than those in the control. It is evident thatthe thymosin F_5 had protective effect on thymus and bone marrow ofexperimental mice with acute radiation sickness.

本文报导从新鲜小牛胸腺制备的胸腺素F_5,对~(60)钴γ射线照射后小白鼠的予防和治疗效果。结果表明:用胸腺素F_5治疗照射动物,其30天存活率可提高35~62.2%。存活动物的胸腺组织较对照组重,骨髓有核细胞计数较对照组高。胸腺素F_5对正常及照射小鼠骨髓干细胞体外培养均有明显刺激作用。初步探讨了胸腺素F_5对急性放射病治疗作用的可能机制。

In order to probe into the patho-genic factors of the esophageal cancerin Sichuan, the mouse bone marrowmicronucleus test of the metabolicextracts of predominant fungi-A. ver-sicolor and P. cyclopium in pickledvegetables was used for the detectionof mutation. 196 mice of three strains were used:C_(57) (174 animals), ICR (12 animals)and Kunming (10 animals). The me-tabolic extracts were injected hypo-dermically once a day for 2, 3 or up to5 days. Six or thirty even fifty fourhours after the last injection, all...

In order to probe into the patho-genic factors of the esophageal cancerin Sichuan, the mouse bone marrowmicronucleus test of the metabolicextracts of predominant fungi-A. ver-sicolor and P. cyclopium in pickledvegetables was used for the detectionof mutation. 196 mice of three strains were used:C_(57) (174 animals), ICR (12 animals)and Kunming (10 animals). The me-tabolic extracts were injected hypo-dermically once a day for 2, 3 or up to5 days. Six or thirty even fifty fourhours after the last injection, all micewere killed and smears of bone marrowof the sternum were obtained bysqueezing it with a hemostat. Afterdrying, the smears were stained withGiemsa's dye and studied under micro-scope in oil immersion. Only the micro-nuclei of polychromatophilic red bloodcells were scored. In each mouse, 1000such cells were examined and thenumber of those bearing micronucleusrecorded. The micronucleus rates of metabolicextracts in ten strains of A. versicolorand that in eight strains of P. cyclopiumwere calculated. Positive results werefound in eight and five strains withsignificant and highly significant dif-ferences respectively. However, thecorrelation between the results of mi-cronucleus test and distribution of theesophageal cancer in the high incidencearea could not be proved. There wasa positive correlation between themicronucleus rates and dosage of me-tabolic extracts of A. versicolor. Inthis test,C_(57) and Kunming mice weremore sensitive to the metabolic extractsof A. versicolor than ICR mice. The optimal time to take the bonemarrow was six or thirty hours after thelast injection, because the micronu-cleus rate was high at that time andwas lower after fifty four hours. This method was successful for thedetection of mutagenicity of the meta-bolic extracts of A. versicolor andP. cyclopium in pickled vegetablescollected from a high incidence area ofesophageal cancer in Sichuan province.The metabolic extracts of A. versicolorin eight of ten strains and that of P.cyclopium in five of eight strains werefound to be mutagenitic. The authorsbelieve that the application of mousebone marrow micronucleus test of fungimetabolic extracts in the examinationof mutation was completely feasible.

本文报告用我省食管癌高发地区,居民食用的酸菜样品中,分离所得优势真菌杂色曲霉及圆弧青霉的代谢提取物,作小鼠骨髓微核试验,进行致突变检测。结果发现大多数菌株具有阳性反应。对杂色曲霉代谢提取物的敏感动物、剂量效应关系以及在体内致突变作用的时间关系,分别进行了检测。

 
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