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骨髓
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  bone marrow
    Preliminary Research on Gene Expression in Mouse Bone Marrow Early after High-dose Radiation in Vivo
    大剂量照射后早期小鼠骨髓表达基因的初步研究
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    Analysis of the Differentially Expressed Genes in Postirradiation Mouse Bone Marrow and Function Investigation of SIRT1
    小鼠骨髓辐射后基因表达差异分析及SIRT1功能研究
短句来源
    INCIDENCE OF CATARACTS OBSERVED IN MICE SURVIVED IRRADIATION AND BONE MARROW TREATMENT
    照射和骨髓治疗活存小鼠中白内障的发生率
短句来源
    THE INFLUENCE OF NEUTRON-GAMMA MIXED RADIATION ON BONE MARROW DNA SYNTHESIS IN MICE
    中子-γ射线混合照射对小鼠骨髓DNA合成的影响
短句来源
    DYNAMIC CHANGES OF SOME INDICES OF BONE MARROW TYPE AND GASTROINTESTINAL TYPE RADIATION SICKNESS IN MICE IRRADIATED WITH 10-16 GY γ-RAYS
    10—16戈瑞照射小鼠某些骨髓型和胃肠型指标的动态变化
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  “骨髓”译为未确定词的双语例句
    There were 20 Wister rats in the group of high exposure dose(2Gy),20 in low dose(0.5Gy). 10 rats were chosen randomly from each group to transplant MSCs,the other 10 as controls.
    高剂量(2Gy)放射线照射组Wister大鼠20只,低剂量(0.5Gy)放射线照射组Wister大鼠20只,各组中随机取10只移植骨髓间充质干细胞作为实验组,剩余未移植大鼠10只作为对照组。
短句来源
    Experimental study of MSCs in treatment of acute hematopoietic radiation injury
    间充质干细胞治疗急性骨髓型放射病的实验研究
短句来源
    Application of DISA SPECT in Evaluating Myocardial Metabolism and Perfusion of Patients with Stem Cell Myocardial Transplantation after Myocardial Infarction
    DISA SPECT对心梗后骨髓干细胞移植心肌灌注和代谢的评价
短句来源
    STUDY ON RADIATION PROTECTION EFFECTS OF ZINC ON MICE MYELOID ELEMENT CULTURED IN VITRO
    锌对体外培养小鼠骨髓造血细胞辐射防护作用研究
短句来源
    Additionally, studies of single or several genes can not meet the systemic requirement.
    对于研究辐射对骨髓系统损伤机制而言,单个或几个基因的研究不能满足实验的需要,所需要的是高通量的研究工具。
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  bone marrow
The effects of hematopoietic stem/progenitor cells (HSPCs) expanded in the two step coculture with human bone marrow mesenchymal stem cells (hMSCs) on the hematopoietic reconstruction of irradiated NOD/SCID mice were studied.
      
Effects of malondialdehyde on growth and proliferation of human bone marrow mesenchymal stem cells in vitro
      
Malondialdehyde (MDA) is a well known inducer of carbonyl stress in a variety of human cells, however, its effects on human bone marrow mesenchymal stem cells (hMSCs) have not been documented.
      
In this study, murine mononuclear cells (MNCs) were isolated from bone marrow and cultured in suspension, and then Lin-CD117+ HSCs were isolated by immunomagnetic beads.
      
Cytokines mRNA in bone marrow-derived dendritic cells in asthmatic mouse
      
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23 cases (4.09%) of intussusception were observed in 562 dogs succumbed to acute radiation sickness or combination with burn and blast injury.All intussusception cases were seen in dogs died of bone marrow death and intestinal death,but not in central nervous system death or immediate rediation death. In treated animals the incidence of intussusception was 6.36%(14/220 cases) while in controls only 2.63%(9/342 cases).The incidence of intussusception in radiation sickness was 0.61%(1/164 cases) and increaced...

23 cases (4.09%) of intussusception were observed in 562 dogs succumbed to acute radiation sickness or combination with burn and blast injury.All intussusception cases were seen in dogs died of bone marrow death and intestinal death,but not in central nervous system death or immediate rediation death. In treated animals the incidence of intussusception was 6.36%(14/220 cases) while in controls only 2.63%(9/342 cases).The incidence of intussusception in radiation sickness was 0.61%(1/164 cases) and increaced to 4.49%(8/178 cases) in combined injury with burn and blast injury.The incidence of intussusception was 7.11%(17/239 cases) in bone marrow death and decreaced to 2.34%(6/256 cases) in intestinal death. The earlest intussusception occured in the dog died at 23.5 th hour after irradia- tion and the latest on 23.9 th day.The average survival time was 11.96±5.64 days. The incidence of intussusception was highest in 2nd-3rd weeks after irradiation.Doses inducing intussusception were 137—4965 rads while most cases were induced by doses between 265—1500 rads.The threshold dose for inducing intussusception in simple radia- tion sickness was 660 rads;in radiation sickness combined with burn it was 265 rads; in radiation sickness combined with burn and blast injury it was 137 rads. Among 23 cases of intussusception there were single intussusception (20 cases) and multiple intussusception including double (2 cases) and triple (1 case) intussusception.Small intestinal intussusception (jejuno-jejunal-and ileo-ileal-intussusception) was about 61%, ileocolic-intussusception was about 17%,duodeno-gastro-intussusception was about 9%, multiple intussusception was about 13%. According to pathological changes,the intussusception may be classified as simple type (5 cases),oedematous type (1 case) and necrotic type (17 cases).These may represent the processes of development of changes.In necrotic type,one could see necrosis of mu- cosa,venous stasis,edema,fibrinous exudation,hemorrhage and infection.The characte- ristic features of intussusception in radiation sickness and combined radiation injury were that the above mentioned changes occured more often and more severe than in common clinical intussusception,and that there were no infiltration of granulocytes.

562例急性放射病与放射复合烧伤、冲击伤死亡狗共发生肠套迭23例(4.09%),全部出现在骨髓型和肠型病例,未见于脑型与射线下死亡者。治疗组动物的肠套迭发生率达6.36%(14/220例),而效应组为2.63%(9/342例);单纯放射病时肠套迭的发生率为0.61%(1/164例),复合烧伤或复合烧伤、冲击伤时为4.49%(8/178例);骨髓型放射病时肠套迭的发生率为7.11%(17/239例),较肠型者2.34%(6/256例)显著增高。肠套迭最早见于照后23.5小时,最迟23.9天死亡狗,平均11.96±5.64天,以照后第二、三周发生率较高。肠套迭病例的照射剂量在137—4965拉德之间,其中265—1500拉德最多见。狗单纯放射病时并发肠套迭的照射阈剂量为660拉德,放烧复合伤时为265拉德,放烧冲复合伤时为137拉德。23例肠套迭中见单套迭(20例)和多套迭两种,后者包括双套迭(2例)和三套迭(1例)。小肠套迭(空空肠套迭和回回肠套迭)约占61%,回结肠套迭约占17%,十二指肠胃套迭约9%,多发型约13%。依据肠套迭病理变化,可分为单纯型(5例)、水肿型(1例)和坏死型(1...

562例急性放射病与放射复合烧伤、冲击伤死亡狗共发生肠套迭23例(4.09%),全部出现在骨髓型和肠型病例,未见于脑型与射线下死亡者。治疗组动物的肠套迭发生率达6.36%(14/220例),而效应组为2.63%(9/342例);单纯放射病时肠套迭的发生率为0.61%(1/164例),复合烧伤或复合烧伤、冲击伤时为4.49%(8/178例);骨髓型放射病时肠套迭的发生率为7.11%(17/239例),较肠型者2.34%(6/256例)显著增高。肠套迭最早见于照后23.5小时,最迟23.9天死亡狗,平均11.96±5.64天,以照后第二、三周发生率较高。肠套迭病例的照射剂量在137—4965拉德之间,其中265—1500拉德最多见。狗单纯放射病时并发肠套迭的照射阈剂量为660拉德,放烧复合伤时为265拉德,放烧冲复合伤时为137拉德。23例肠套迭中见单套迭(20例)和多套迭两种,后者包括双套迭(2例)和三套迭(1例)。小肠套迭(空空肠套迭和回回肠套迭)约占61%,回结肠套迭约占17%,十二指肠胃套迭约9%,多发型约13%。依据肠套迭病理变化,可分为单纯型(5例)、水肿型(1例)和坏死型(17例)。三型可能是肠套迭局部病变由轻到重依次发展的过程。肠套迭局部粘膜坏死、静脉淤滞、水肿、纤维素渗出、出血,并发细菌感染。其特点是上述病变较临床上肠套迭更多见,更严重;病变部位缺乏炎细胞反应。

A number of 180—200 gram healthy adult rats were dividedinto two groups.One group were simply irradiated with various doses(100—600 fads)of ~(60)Co γ-rays,and the other group were exposed to samedosage of γ-rays in eombination with 15% 2nd degree burns.The incidenceof chromosomal aberrations in cells of bone marrow of both groups of ratswere examined 24 hours later.The incidence of all type of chromosomalaberrations between simple burn group and the control group,between theirradiation-burn group and the simple...

A number of 180—200 gram healthy adult rats were dividedinto two groups.One group were simply irradiated with various doses(100—600 fads)of ~(60)Co γ-rays,and the other group were exposed to samedosage of γ-rays in eombination with 15% 2nd degree burns.The incidenceof chromosomal aberrations in cells of bone marrow of both groups of ratswere examined 24 hours later.The incidence of all type of chromosomalaberrations between simple burn group and the control group,between theirradiation-burn group and the simple irradiated group were very similar.Thedifference between them was not significant.By regression analysis it showedthat:not only were their models the same,but also the regression equationsof the same indicators of the above-mentioned groups were almost equal.The above results showed that combination with 15% 2nd degree burnsdidn't affect incidence of γ induced chromosomal aberrations in the cells ofbone marrow,so the incidence of chromosomal aberrations of bone marrowcells can still be used as a biological dosimeter for the individuals withirradiation-burn damage.

100—600拉德~(60)Coγ线和该剂量复合15%二度烧伤各组,伤后24小时,单纯烧伤和对照组之间,放烧复合伤和单纯照射组之间,染色体畸变无显著性差异,经回归分析表明,不仅模式相同而且同一指标的回归方程式几乎相等,大鼠复合15%二度烧伤对骨髓细胞染色体畸变没产生影响,因此,染色体畸变分析有作为放烧复合伤时生物剂量仪的可能性。

The effects of dose fractionation on the survival rate, the numbers ofbone marrow cells (BMC) and hemopoietic stem cells (CFU-S) per femur, and the self-renewal capacity of the CPU-S in ICR/JCL and LACA mice were investigated. It wasfound that dose fractionation affected the mouse survival rate significantly. At 2 monthsafter 18 Gy irradiation. the survival rates of mice received 6 doses of 3.0 Gy and 4 dosesof 4.5 Gy were about 40% and 15% respectively, but all mice died after 3 doses of 6.0Gy. When the total...

The effects of dose fractionation on the survival rate, the numbers ofbone marrow cells (BMC) and hemopoietic stem cells (CFU-S) per femur, and the self-renewal capacity of the CPU-S in ICR/JCL and LACA mice were investigated. It wasfound that dose fractionation affected the mouse survival rate significantly. At 2 monthsafter 18 Gy irradiation. the survival rates of mice received 6 doses of 3.0 Gy and 4 dosesof 4.5 Gy were about 40% and 15% respectively, but all mice died after 3 doses of 6.0Gy. When the total dose of 12 Gy was split into 2-4 fractions, most mice survivedmore than 5 months. Although the numberof BMC per femur recovered to normal ornear normal level after 2 months of irradiation, the number of CFU-S per femur wasonly about 40% and the self-renewal capacity of the CFU-S was only about 25% of theage-paired controls. This kind of hemopoietic residual damage remained unchanged up to11 months after irradiation and no significant differences were found among the variousdose fractionation groups.

研究了剂量分割对ICR/JCL和LACA小鼠的活存率,股骨中骨髓细胞(BMC)和造血干细胞(CFU-S)数,以及CFU-S自我更新能力的影响。剂量分割对小鼠的存活率有明显的影响。在18Gy照射后2个月,接受3.0Gy 6次照射和4. 5 Gy 4次照射的小鼠分别活存40%和15%,但6.0 Gy3次照射小鼠已全数死亡。当总剂量12Gy分割成2—4次照射时,大多数小鼠能活存5个月以上。虽然每根股骨中的BMC数在照后2个月恢复至正常或接近正常水平,但股骨CFU-S含量只相当于同令对照的40%,CFU-S自我更新能力只相当于25%。这种造血残留损伤在照后11个月时仍然存在,在不同的剂量分割组之间未见明显的差别。

 
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