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骨髓
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  bone marrow
    Effects of Surface Modification of Biogegradable Polymers PLGA on the Adhesion, Proliferation and Differentiation of Rabbit Bone Marrow Stromal Cells in Vitro and in Vivo
    组织工程材料的表面修饰对骨髓基质细胞粘附、增殖及定向成骨细胞分化的影响及体内成骨效应
短句来源
    Experimental Study on Tissue Engineering of Heart Valves with Bone Marrow Mesenchymal Stem Cells
    骨髓间质干细胞构建组织工程心脏瓣膜的实验研究
短句来源
    Experimental Study on Transfecting Gene into Bone Marrow Mesenchymal Stem Cells to Develop Tissue Engineering Heart Valves
    基因转染骨髓间质干细胞构建组织工程心脏瓣膜的实验研究
短句来源
    Experimental Studies on One New Tissue-engineering Bone Using Bone Marrow Mesenchymal Stem Cells, Bovine Bone Morphorgenetic Protein and Silk Fibroin
    构建骨髓间充质干细胞/牛骨形态发生蛋白/丝素蛋白组织工程骨的实验研究
短句来源
    Experimental Research on Construction of Small Diameter Tissue Engineering Blood Vessel with Bone Marrow Mesenchymal Stem Cells
    骨髓间充质干细胞构建小口径组织工程化血管的实验研究
短句来源
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  human marrow
    Biocompatibility between Nacre-PDLLA artificial bone and human marrow stroma cells
    珍珠层人工骨与人骨髓基质细胞的生物相容性
短句来源
    In vivo chondrogenesis of induced human marrow mesenchymal stem cells in nude mice
    诱导的人骨髓间充质干细胞在裸鼠体内生成软骨的实验研究
短句来源
    Cytocompatibiltiy of degradable calcium metaphosphate with human marrow mesenchymal stem cells
    人骨髓间质干细胞与新型可降解材料生物相容性的实验研究
短句来源
    Objective: To investigate the feasibility of constructing tissue engineering heart valves (TEHV) by human autologous saphenous venous derived endothelial cells (hECs) and myofibroblasts (hMFbs), and human marrow mesenchymal stem cells (hMSCs) for the future clinical application.
    目的:探索以人自体大隐静脉内皮细胞及骨髓间充质干细胞构建组织工程心脏瓣膜(TEHV)的可行性,为将来的临床应用奠定基础。
短句来源
    YHPD plus light irradiation was selectively more efficient for killing K 562 cells than normal human marrow progenitors. Under the condition of a 5log reduction in the survival of K 562 cells, 15.97% of normal human CFU GM survived. These results indicate that the photochemotherapy mediated by YHPD might be used for purging bone marrow in vitro.
    YHPD加光照对K562细胞具有强大杀伤作用,对正常造血祖细胞影响较小,在能够杀伤白血病细胞大于5个对数级,其体外已不能形成集落的情况下,正常人骨髓-巨噬细胞集落形成单位(CFU-GM)尚有15.97%,提示该法可望用于骨髓体外净化
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  “骨髓”译为未确定词的双语例句
    Cartilage Induction of Human Mesenchymal Stem Cells and Experiment on Compound Porous Materials as Cells' Scaffold in Vitro
    人骨髓基质干细胞成软骨诱导及多孔复合材料作为细胞载体的体外实验研究
短句来源
    Application of Mesenchymal Stem Cells in Tissue Engineered Skin
    骨髓间充质干细胞在组织工程皮肤中的应用
短句来源
    Constructing Tissue-engineering Cartilage with TGF-β1 Gene Modified Mesenchymal Stem Cells Loaded in Chitosan
    TGF-β1基因修饰骨髓间充质干细胞复合壳聚糖构建组织工程软骨
短句来源
    Articular Cartilage Tissue-engineering Based on MSCs and Biodegradable Porous Bioceramics
    基于骨髓间充质干细胞和可降解多孔生物陶瓷材料的关节软骨组织工程研究
短句来源
    RESULTS:①In the orientational cultivation,5.0×105 of BMSCs in the primary culture was increased to 6.0×109 of ECs,that was increased 1.2×104 times after 8 generations incubated,which could satisfy the requirement of high density seeding.
    结果:①5.0×105个骨髓基质细胞体外定向培养的内皮细胞共传8代,最后获得了6.0×109个内皮细胞,扩增了约1.2×104倍,可以满足高密度种植内皮细胞的需求。
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  bone marrow
The effects of hematopoietic stem/progenitor cells (HSPCs) expanded in the two step coculture with human bone marrow mesenchymal stem cells (hMSCs) on the hematopoietic reconstruction of irradiated NOD/SCID mice were studied.
      
Effects of malondialdehyde on growth and proliferation of human bone marrow mesenchymal stem cells in vitro
      
Malondialdehyde (MDA) is a well known inducer of carbonyl stress in a variety of human cells, however, its effects on human bone marrow mesenchymal stem cells (hMSCs) have not been documented.
      
In this study, murine mononuclear cells (MNCs) were isolated from bone marrow and cultured in suspension, and then Lin-CD117+ HSCs were isolated by immunomagnetic beads.
      
Cytokines mRNA in bone marrow-derived dendritic cells in asthmatic mouse
      
更多          
  human marrow
Expansion of CD34+ cells from human umbilical cord blood by FL and/or TPO gene transfected human marrow stromal cell lines
      
The expression of P-gp on the surface of CD34+ cells from healthy human marrow was examined by flow cytometry.
      
Human marrow was obtained as material discarded during total hip replacement and was established in culture with phenol red-free α-MEM with 10% fetal bovine serum (FBS) and antibiotics.
      
Insulin-like growth factor I (IGF-I) and its binding proteins were secreted by human marrow cells, in amounts that increased with time in culture.
      
In this pilot study, we evaluated the efficiency of a selective depletion of human marrow T cytotoxic lymphocytes (CD8), a subset essential to induce GVHD in mice.
      
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1. An evaluation of toxicity and safetyPolyvinylalcohol(PVA), with molecular weights of 20, 000-30, 000, is one of the synthetic polymers that has been used in medicine. It can be absorbed into the blood. In this study its LD 50 was found to be 11, 833mg/kg or 13.428mg/kg (mouse. i. p), cumulative coefficient k>5, manifesting low toxicity. However, in experimental animals it may cause toxic effects Whilt the dose was over 2.5g/kg/day×7 or 5g/kg/day×3.The effects of PVA on liver and kidney tissue have been observed....

1. An evaluation of toxicity and safetyPolyvinylalcohol(PVA), with molecular weights of 20, 000-30, 000, is one of the synthetic polymers that has been used in medicine. It can be absorbed into the blood. In this study its LD 50 was found to be 11, 833mg/kg or 13.428mg/kg (mouse. i. p), cumulative coefficient k>5, manifesting low toxicity. However, in experimental animals it may cause toxic effects Whilt the dose was over 2.5g/kg/day×7 or 5g/kg/day×3.The effects of PVA on liver and kidney tissue have been observed. No tissue damage was found with a dosage lower than 0.5g/kg/day×30, but with doses over 2.5g/kg/day×7 or 5g/kg/day ×39 degeneration and necrosis of liver and kidney were demonstrated.In conculusion: PVA toxicity and safety is relative to the dose adminstered.2. The effect of PVA on hematologyThe effects of PVA on hematology have been observed. results showed that haemolysis rate was<5 %, W. B. C was slightly increased and Hb decreased; haemopoietic stem cells showed no damage, micronuclei rate was not increased, These findings suggested that PVA has acceptable blood compatibility.

本文从低聚合度PVA对造血系统影响的研究指出:PVA的体外溶血率小于5%,白细胞有轻度增高,血色素下降,造血干细胞和骨髓嗜多染性红血球微核率未受影响,因此PVA具有较好的血液相容性。

The intramedullary nailing in fixation of femoral shaft fractures is roy prevalent today. However, the e are some cases with nail angulation or broken nails occasionally encounted. In followup of 67 operations the autho s have collected 4 cases(6%)with 15° angulation in their own hospital and 3 cases with 15°-13°(average 21°) angulation transferred from othe: units Of the 7 cases, 3 we e associated with nail b eaks, all of which use V-shaped nails.The authors designed an experiment fo biodynamic observation...

The intramedullary nailing in fixation of femoral shaft fractures is roy prevalent today. However, the e are some cases with nail angulation or broken nails occasionally encounted. In followup of 67 operations the autho s have collected 4 cases(6%)with 15° angulation in their own hospital and 3 cases with 15°-13°(average 21°) angulation transferred from othe: units Of the 7 cases, 3 we e associated with nail b eaks, all of which use V-shaped nails.The authors designed an experiment fo biodynamic observation which proved that the ability of anti-angulation in V-shaped nails were significantly lowe than that of the plum floweshaped nails, especially used in cases of comminuted, oblique fractures and under some conditions such as sustained in extra-traumatic force, the V-shaped nail easily deformed. The direction of nail insertion markedly influenced the nailing quality. If the open side of the V-shaped nail faced the medial aspect of the ext emily it pored to be stronger than that which faced the lateral side of the ext emity. The latter resulted in lowe lug of 18.8% of the anti-angulating force, as shown in the 4 cases in the p esent series. The experiment also proved that if the e was cortical defect at the fracture site, cortical support against forces of strain would be lost and would increase the nail strain. In other words, the V-shaped nail decreased 21.9%in anti-angulating force. Such angulation happened in 6 cases. The remaining case in nail angulation was caused by trauma.

本文通过对7例股骨髓针固定术后发生弯曲折断的分析,结合对髓针的抗弯性能测试,提出髓针发生弯曲折断的力学因素。 7例全部是V形體针,测试证明V形针的抗弯性能明显低于梅花形體针,V形针不能承受某些异常因素增加的弯曲应力。在粉碎骨折、斜形骨折和外伤情况下,容易发生变形。并发现,V形针置针方向对其抗弯性能很有影响,即V形顶角在外侧其抗弯性能较强,相反,如V形顶角在内侧而开口向外侧者,抗弯性能即减弱18.8%。本文有4例即是V形针顶角在内侧而发生弯曲折断者。 经测试,在骨折时如股骨内侧皮质缺损,从而失掉接触支撑力时,V形针的抗弯性能减少21.9%,在粉碎骨折和斜形骨折,由于内侧支点的丧失,使髓针承受过大的弯曲应力,而发生髓针弯曲折断的现象,本组即有5例。

The susceptibility between murine bone marrow hemopoietic cells and splenic lymphocytes to four major factors was compared. These factors included toxicity of DMSO, cooling rate, Tris-NH4Cl treatment, and dilution. When the concentration of DMSO was high above 20%, the proliferative functions or viability of both kinds of cells decreased severely. Hemopietic stem cells and lymphocytes were more injured in rapid cooling than in slow cooling and their damage intensity seemed alike at the same fast cooling condition....

The susceptibility between murine bone marrow hemopoietic cells and splenic lymphocytes to four major factors was compared. These factors included toxicity of DMSO, cooling rate, Tris-NH4Cl treatment, and dilution. When the concentration of DMSO was high above 20%, the proliferative functions or viability of both kinds of cells decreased severely. Hemopietic stem cells and lymphocytes were more injured in rapid cooling than in slow cooling and their damage intensity seemed alike at the same fast cooling condition. Pretreatment of bone marrow cells with Tris-HN4Cl did not significantly accentuate injury of frozen-thawed hemopoietic stem cells.Diluting frozen-thawed cells at ice bath or rapidly was harmful to both cells. No significant differential susceptibilities of both kinds of cells to every factor were found. These results indicate that to selectively destroy or inactivate lymphocytes among bone marrow cells may be impossible.

本实验研究了小鼠骨髓造血细胞和脾淋巴细胞对二甲基亚砜、降温速率、Tris-NH4Cl以及复温后处理这4个主要冻存损伤因素的敏感性差异。发现高浓度二甲基亚砜、快速降温、复温后快速稀释对造血细胞和淋巴细胞都有明显的损伤效应。它们的台盼蓝着染率增加,增殖能力下降,甚至几乎丧失。但是两种细胞对冷冻损伤的敏感性无明显差异。提示难以用冷冻方式选择性地杀灭造血组织中的免疫活性细胞。

 
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