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   小叶增生症 的翻译结果: 查询用时:0.023秒
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小叶增生症
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  breast proliferative disease
     Methods:The expression of PCNA was detected by s-p immunohisto-chemistry method in 63 cases of primary breast carcinoma and 11 cases of breast proliferative disease. The expression degree of PCNA in different histological grades,clinical stages and lymph node metastasis were analyzed.
     方法:采用免疫组化S-P法,检测63例原发性乳腺癌和11例乳腺小叶增生症中PCNA的表达,并分析其在不同病理分级、临床分期及有无淋巴结转移病例中的表达强度。
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  lobular hyperplasia
     The parafin-embedded tissue blocks of 50 primary breast carcinoma, 10 breast fibroadenoma and 10 lobular hyperplasia were reviewed by PAP method for staining estrogen receptor ( ER ) , progestrone receptor ( PR ) and carcinoembryonic antigen ( CEA ) , with the nuclear DNA content in 30 specimens of carcinoma measured with JX-1 medical image analysis system.
     应用PAP方法对50例乳腺癌、10例乳腺纤维瘤和10例乳腺小叶增生症石蜡切片进行雌激素受体、孕激素受体和癌胚抗原检测,其中30例乳腺癌应用JX-1医用图象分析系统测定了细胞核DNA含量。
短句来源
     Methods: Breast lobular hyperplasia was induced by estradiol(E2 0. 2 mg/d, im, for 30 days). Tamoxifen(TAM), an antiestrogen,was added to the feed in a dose of 0. 5 mg/d for 30 days.
     方法:用苯甲酸雌二醇(estradiol,E2)诱发卵巢健全小鼠乳腺小叶增生症,E2剂量为0.2mg/d肌肉注射,连续30d,以TAM0.5mg/d拌入饲料中,连续喂养30d。
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  “小叶增生症”译为未确定词的双语例句
     Efficacy of Tamoxifen for Breast Cystic Hyperplasia
     他莫昔芬治疗乳腺小叶增生症(附288例报告)
短句来源
     Methods: Immunohistochemical EnVision method was used to detect the expression of E--cad, cyclinD_1 and Ki--67protein in 63 cases with IDC(the IDC group), 15cases with adenoma and 15 cases with adenosis(the constrast group).
     方法:用免疫组织化学EnVision二步法检测63例乳腺浸润性导管癌(invasive ductal carcinoma,IDC)组织中E--cad、cyclinD_1、Ki--67蛋白的表达情况,设为IDC组; 另检测15例乳腺纤维腺瘤及15例乳腺小叶增生症乳腺组织中E--cad、cyclinD_1、Ki--67蛋白的表达情况,设为对照组。
短句来源
     Methods 288 cases of breast cystic hyperplasia were entered randomly as experimental group,it was given tamoxifen 10mg~20mg Bid for 1~3 months;
     方法 门诊随机选择乳腺小叶增生症患者治疗组 2 88例 ,用他莫昔芬 10mg ,每日 2次 ,半月复诊一次 ,待症状缓解后改 10mg每日维持 ,根据临床分型用药 1~ 3个月。
短句来源
     Treatment of 31 Cases Lobes of Mammary Gland Hyperplasia With Promoting Qi and Removing Blood Stasis and Phlegm
     行气化瘀消痰法治疗乳腺小叶增生症31例临床观察
短句来源
     Objective To study the clinical effect of tamoxifen on the treatment of breast cystic hyperplasia.
     目的 探讨他莫昔芬治疗乳腺小叶增生症的疗效。
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  相似匹配句对
     Drug Therapy of Benign Prostatic Hyperplasia
     前列腺增生的药物治疗
短句来源
     Giant Lymph Node Hyperplasia
     巨大淋巴结增生
短句来源
     Objective To study the clinical effect of tamoxifen on the treatment of breast cystic hyperplasia.
     目的 探讨他莫昔芬治疗乳腺小叶增生的疗效。
短句来源
     Efficacy of Tamoxifen for Breast Cystic Hyperplasia
     他莫昔芬治疗乳腺小叶增生(附288例报告)
短句来源
     Treatment of 31 Cases Lobes of Mammary Gland Hyperplasia With Promoting Qi and Removing Blood Stasis and Phlegm
     行气化瘀消痰法治疗乳腺小叶增生31例临床观察
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  lobular hyperplasia
On final histological diagnosis, there were 56 malignant tumours, 14 benign nodules (9 fibroadenomas, two cases of adenosis, two cases of focal fibrosis and one case of epitheliosis) and six atypical lesions (atypical ductal or lobular hyperplasia).
      
All cases of histologically verified lobular carcinoma in situ, atypical ductal or lobular hyperplasia, radial scar or atypical papillary lesion were correctly diagnosed preoperatively.
      
Sclerosing lobular hyperplasia: sonographic pathologic correlation
      
The objective was to evaluate the sonographic findings of sclerosing lobular hyperplasia (SLH) of the breast and to correlate the sonographic findings and the pathologic features.
      
This study consisted of 9 patients with pathologically proven sclerosing lobular hyperplasia who had undergone a preoperative imaging study.
      
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The parafin-embedded tissue blocks of 50 primary breast carcinoma, 10 breast fibroadenoma and 10 lobular hyperplasia were reviewed by PAP method for staining estrogen receptor ( ER ) , progestrone receptor ( PR ) and carcinoembryonic antigen ( CEA ) , with the nuclear DNA content in 30 specimens of carcinoma measured with JX-1 medical image analysis system. The results showed : ( 1 ) the positive rate for ER, PR and CEA of breast carcinoma wes 68%, 66% and 64% respectively, ( 2 ) the 3 biological markers were...

The parafin-embedded tissue blocks of 50 primary breast carcinoma, 10 breast fibroadenoma and 10 lobular hyperplasia were reviewed by PAP method for staining estrogen receptor ( ER ) , progestrone receptor ( PR ) and carcinoembryonic antigen ( CEA ) , with the nuclear DNA content in 30 specimens of carcinoma measured with JX-1 medical image analysis system. The results showed : ( 1 ) the positive rate for ER, PR and CEA of breast carcinoma wes 68%, 66% and 64% respectively, ( 2 ) the 3 biological markers were closely correlated with the degree of differentiation of the cancer tissue, ( 3 ) the correlationship was good between the biological markers and the DNA content. These findings indicate that detection of CEA could be a supplementary means for early and differential diagnosis of breast carcinoma, and that the 3 biological markers and DNA content might be used as important parameters to understand the growth state and estimate the prognosis.

应用PAP方法对50例乳腺癌、10例乳腺纤维瘤和10例乳腺小叶增生症石蜡切片进行雌激素受体、孕激素受体和癌胚抗原检测,其中30例乳腺癌应用JX-1医用图象分析系统测定了细胞核DNA含量。结果表明:(1)三种生物学标志物在乳腺癌的表达率分别为68%、66%和64%;(2)三种生物学标志物的表达与乳腺癌分化程度密切相关;(3)三种生物学标志物与乳腺癌细胞核DNA含量具有良好的相关性。提示:癌胚抗原在乳腺癌有较高的表达率,可望作为乳腺癌早期诊断和鉴别诊断的辅助手段;三种生物学标志物和D-NA含量能够反映乳腺癌的分化程度,均可作为评估预后的指标。

Three lectin receptors of tissues from 50 cases of breast carcinomas and 20 cases breast benign lesions were studied with ABC method. The results showed that there was no significant difference in the expression of three lectin receptors between breast benign and malignant lesions. The ConA receptor of breast carcinomas was mainly localized in the cytoplasm,while that of fihroadenoma mainly in the cytomembrane (P<0. 05). Both LCA and PSA receptors were mainly localized in the cytoplasm in three breast lesions....

Three lectin receptors of tissues from 50 cases of breast carcinomas and 20 cases breast benign lesions were studied with ABC method. The results showed that there was no significant difference in the expression of three lectin receptors between breast benign and malignant lesions. The ConA receptor of breast carcinomas was mainly localized in the cytoplasm,while that of fihroadenoma mainly in the cytomembrane (P<0. 05). Both LCA and PSA receptors were mainly localized in the cytoplasm in three breast lesions. There was good correlation beween ConA receptor expression and the differentiation of breast carcinoma as well as in LCA receptor expression and the tumor size. There were no clear relationships between the expression of three lectin receptors and CEA. ER and PR of breast carcinoma.

运用ABC法研究50例乳腺癌三种凝集素受体(Lectin-R)的表达,并以乳腺纤维瘤和乳腺小叶增生症各10例作为对照。结果表明:该三种凝集素受体在乳腺良、恶性病变中的表达率无显著性差异。COnA-R在乳腺癌以胞浆型定位为主,在纤维腺瘤则以胞膜型多见(P<0.05)。LCA-R和PSA-R在乳腺三种病变中均以胞浆型为主。ConA-R与乳腺癌分化程度具良好的相关性;LCA-R与乳腺癌瘤体大小有关。该三种凝集素受体与ER、PR及CEA的表达未显示密切的关联。

Objective:To establish a model of breast lobular hyperplasia in mice with normal ovaries and to evaluate the curative effect of tamoxifen on the animal model. Methods: Breast lobular hyperplasia was induced by estradiol(E2 0. 2 mg/d, im, for 30 days). Tamoxifen(TAM), an antiestrogen,was added to the feed in a dose of 0. 5 mg/d for 30 days. Results: The breast lobular hyperplasia was really induced in 22 mice injected with E2. By light microscopy, there were lesions similar to human simple lobular hyperplasia...

Objective:To establish a model of breast lobular hyperplasia in mice with normal ovaries and to evaluate the curative effect of tamoxifen on the animal model. Methods: Breast lobular hyperplasia was induced by estradiol(E2 0. 2 mg/d, im, for 30 days). Tamoxifen(TAM), an antiestrogen,was added to the feed in a dose of 0. 5 mg/d for 30 days. Results: The breast lobular hyperplasia was really induced in 22 mice injected with E2. By light microscopy, there were lesions similar to human simple lobular hyperplasia of breasts in 9 mice(41%), similar to human adenoid lobular hyperplasia in 6(27%), similar to human papillomatosis in 5(23%) and similar to human cystic hyperplasia in 2(9%). And there were mild, moderate and severe epithelial hyperplasia in 12(54%), 5(23%) and 5(23%), respectively. An alleviative effect on lobular hyperplasia was shown when TAM was preventively or therapeutically used.Immunolabelling method showed that the positive rates of antiestradiol and antiprogesterone of rabbit to experimental animal were 41% and 9%, respectively. Conclusion: The breast lobular hyperplasia in mice with normal ovaries can be well induced by E2 with a dose of 0.2 mg/d, for 30 days,and it is a modified animal model.TAM has markedly preventive and therapeutical effect on breast lobular hyperplasia in mice.

目的:建立卵巢健全乳腺小叶增生模型,评估Tamoxifen(TAM)对小鼠乳腺小叶增生的治疗效果。方法:用苯甲酸雌二醇(estradiol,E2)诱发卵巢健全小鼠乳腺小叶增生症,E2剂量为0.2mg/d肌肉注射,连续30d,以TAM0.5mg/d拌入饲料中,连续喂养30d。结果:模型组注射E222只小鼠均发生乳腺小叶增生病变,光镜下9只(41%)形态似人类单纯性小叶增生,6只(27%)形态似人类腺性小叶增生,5只(23%)形态似人类乳头状瘤病,2只(9%)形态似人类囊性小叶增生。其中上皮呈轻度增生12只(54%),高度增生5只(23%),不典型增生5只(23%)。预防组及治疗组病变明显减轻。免疫标记:兔抗雌二醇阳性率41%,兔抗孕酮阳性率90%。结论:E20.2mg/d连续用30d,可造成卵巢健全小鼠乳腺小叶增生的新模型,TAM具有明显抑制和治疗乳腺小叶增生的作用。

 
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