Objective To examine the expression of endothelin-1(ET-1), somatostatin receptor 2(SSR_2), angiotensin Ⅱreceptor type 1(AT_1) and prostaglandin-E_2 receptor(ER_2) in the hepatic stellate cells of experimental rat liver fibrosis, and to investigate the effect of interleukin-10 on them.
Objectives: To investigate the protective effects of silymarin liposomes (L-SIL) on the acute experimental hepatitis induced respectively by carbon tetrachloride (CCL4), D-galactosamine (D-Ga1N), Bacillus Calmette-Guerin (BCG) plus lipopolysaccharides (LPS) compared with silymarin tablets (T-SIL) and to study the acute toxicity of L-SIL.
Both the approaches showed good correlation between experimental and observed biological activity in both training (r >amp;gt; 0.8) and test set (r =0.75 for 2D and r =0.68 for 3D QSAR model) with statistical significance >amp;gt; 99.5%.
It is demonstrated that the results of inverse computation by that method are more similar to the experimental ones measured by some destructive method.
The experimental results show that the adsorption isotherm of naringin by X-5 resin can be described by the Langmuir isotherm equation.
The fundamental experimental outcome above may provide a new clue for red tide chemical forecast by inspecting the NO change.
The errors of the model are quite close to the experimental errors.
An experimental rat model of Parkinson's disease induced by Japanese encephalitis virus
The authors have used an experimental rat model of chronic aluminum (Al) intoxication to reproduce pathological signs analogous to those observed in humans for Alzheimer's disease or dialysis encephalopathy.
An experimental rat model of aluminum accumulation in the brain was developed to aid in determining neurotoxity of aluminum (Al).
The aim of this project was to study, at high resolution, the spatial distribution of lead in enamel and coronal dentine using an experimental rat model.
S 100 protein in experimental rat tumors of the central and peripheral nervous system