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    Study on the Clinical Risk Factors, Polymorphism of Lipoprotein Lipase Gene and Its Post-heparin Plasma Activity Among Patients with Premature Coronary Heart Disease
    早发冠心病患者临床危险因素、脂蛋白脂酶P,H基因多态性及其酶活性研究
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    The Expression of Adhesion Molecules in Serum of Patients with CHD and Intervention Study with AT_1 Receptor Antagonists
    粘附分子在冠心病患者血清中的表达及AT_1受体拮抗剂的干预研究
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    The Study on Vulnerable Blood in the Elderly Male Patients with CAD and Effect of Hcy on the Expression of TM and TFPI in ECV304 Cells
    老年男性冠心病患者脆性血液的临床研究及Hcy对内皮细胞表达TM和TFPI的影响
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    The Study of Angiographic Evaluation on Tissue Level Perfusion in Patients with Non-ST-eleva-tion Acute Coronary Syndrome
    非ST段抬高型急性冠脉综合征患者组织微灌注的冠脉造影评价研究
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    Clinical Trials of AngⅡ Blockers in Treating Patients with Both Type 2 Diabetes Mellitus and Atherosclerosis, and the Relationship between ACE (I/D), AT_1R (A1166C) Gene Polymorphism and Early Effectiveness of ACEI
    T2DM合并AS患者ACE(I/D)、AT_1R(A1166C)基因多态性与ACEI近期疗效相关性的研究
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  in patient with
    Evaluation of Right Ventricular Function in Patient with Chronic Cor Pulmonale by Gamma Cardiac Function Device
    心功能仪对肺心病患者右心功能的评价
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    COXSACKIE B VIRUS INFECTION IN PATIENT WITH SUSPECTED VIRAL MYOCARDITIS
    上海15所医院病毒性心肌炎患者中柯萨奇B组病毒感染情况
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    Study of Relationship between LVMI and Arrhythmia in Patient with Hypertension
    超声检测高血压病患者左室心肌重量指数与心律失常关系的探讨
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    Resistance of Circulation in Patient with Coronary Heart Disease
    冠心病患者的循环阻力
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    Objective To explore predictive value of high sensitivity C-reaction protein(hsCRP) for assessing follow-up short-term brain infarction in patient with atrial fibrillation.
    目的探讨高敏C-反应蛋白(hsCRP)对心房颤动(AF)患者近期发生脑梗死的预测价值。
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    Changes of Coupling Factor 6 and Brain Natriuretic Peptide 1-76 in Primary Hypertension
    高血压患者偶联因子6、脑钠肽1-76变化
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    Effect of HMG-COA Reductase Gene Polymorphism on the Rate of Reaching Lipid Target in Hyperlipidemic CHD Subjects Using Atorvastatin
    HMG-COA还原酶基因多态性及阿托伐他汀对冠心病高脂血症患者降脂达标率的研究
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    Cyclin D1、ERCC1 Gene Polymorphism and Susceptibility to Childhood Acute Lymphoblastic Leukemia in a Chinese Population
    中国儿童急性淋巴细胞白血病患者Cyclin D1、ERCC1基因多态性的研究
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    The Immunoreactivity and Effect on Platelet Aggregation of ITP IgG Antibody and Its Fragments
    ITP患者IgG酶切片段的免疫活性及其对血小板聚集功能的影响
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    CLINICAL ANALYSIS OF HEMODYNAMIC CHANGES IN ESSENTIAL HYPERTENSION
    原发性高血压患者血液动力学变化的临床分析
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  patients
Genomic DNA was extracted from blood samples of healthy controls and from patients with HBV infection.
      
The immunoassay was used to check the BALP of the blood serum that was from 42 primary osteosarcoma patients.
      
The patients were followed up from five months to 49 months with an average of 24.3 months.
      
Detection of abnormal myocardial perfusion is crucial to the prognosis of patients with coronary artery disease (CAD) after they have undergone percutaneous coronary intervention (PCI).
      
For those patients with acute or total occlusion, the levels of myocardial perfusion before and after PCI were similar, as determined by IC-MCE and visually analyzed from 61 segments (P >amp;lt; 0.05).
      
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Successful thrombolysis in patient with right heart thromboembolism
      
Results of various studies: In patient with ischemic-conditioned heart failure, the reduction of mortality with beta blockers is attributed to a reduction of sudden cardiac death.
      
Recurrent nephrotic syndrome in patient with multiple sclerosis treated with interferon beta-1a
      
The circadian rhythm of body core temperature (CRT) is normal in patient with congenital generalized anhidrosis
      
Night-time HRV did not differ in patient with and without autonomic neuropathy.
      
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The clinical features of 415 attacks of rheumatic fever observed in 365 adult patients are described, and some of the diagnostic problems are discussed, 102 of the attacks were considered to be initial and 313 recurrent attacks. Pre-existing chronic valvular disease was diagnosed in 184 cases. The attack rate of rheumatic fever by season was found to be highest in late Winter and Spring, with the peak incidence in the months of March and April. A history of preceding sore throat was elicited in 41% of the rheumatic...

The clinical features of 415 attacks of rheumatic fever observed in 365 adult patients are described, and some of the diagnostic problems are discussed, 102 of the attacks were considered to be initial and 313 recurrent attacks. Pre-existing chronic valvular disease was diagnosed in 184 cases. The attack rate of rheumatic fever by season was found to be highest in late Winter and Spring, with the peak incidence in the months of March and April. A history of preceding sore throat was elicited in 41% of the rheumatic attacks, and inflammatory signs in the pharynx and tonsils were observed in 58.6% of the attacks. The antistreptolysin O titer was above 250 units in 80% of the cases examined. Among the clinical manifestations arthritis and carditis were most common, occurring in 55.7% and 49.9% respectively, while arthralgia without frank inflammatory signs was noted in 30% of the attacks. The incidence of arthritis was lower in the cases with chronic valvular defects than in cases without. In 29% of the cases ECG abnormalities constituted the sole clinical evidence of carditis. Since prolongation of P-R interval or higher grades of atrioventricular block are relatively common in rheumatic fever and other manifestations of rheumatic carditis like murmurs, cardiac enlargement, pericarditis and heart failure are equally non-speclfic, it is suggested that a-v block be included as evidence of carditis rather than considered as a minor manifestation if one adopts Jones' criteria for the diagnosis of rheumatic fever. In the presence of chronic valvular disease frank arthritis was uncommon and signs of carditis were often masked by those of valvular defects so that in 38.5% of cases the diagnosis of rheumatic activity had to depend upon a combination of clinical and laboratory signs generally concidered as minor rheumatic manifestations according to Jones' criteria.

1.本文报告成人急性风湿热366例,經住院观察的急性发作共415次,其中102次診断为初发,313次为复发。发作見于已有慢性心瓣缺损者計184例(218次发作),无心瓣缺损証据者182例(197次发作)。对发病季节、与溶血性鏈球菌感染的关系、临床表現、实验室发見、病程及病死率等作了分析。重点討論了本病的診断问題。 2.风湿热在春冬二季的发病率較高,41%的风湿发作前有咽痛,58.6%的风湿发作时咽部尚有炎症表現,仅24.7%的风湿发作前后均无咽炎的証据。約有80%发作中抗鏈球菌溶血素“O”滴定度在250单位以上。以上数字有力地說明了风湿热和鏈球菌感染之间的密切关系。 3.临床表現中以关节炎最为常見,发生率为55.7%,仅有关节酸痛的有30%。已有慢性心瓣缺损的病例中仅37.6%有关节炎,其发生率远低于无慢性心瓣缺损的病例(75.6%)。 4.心炎見于49.9%的发作中,其临床表現有时颇不明显。仅在心电图檢查中发見者有41例,占所有經过心电图檢查的心炎病例的29%。由此可見心电图检查对診断心炎的独特价值。 5.在曾作心电图檢查的250次发作中有82次(32.8%)发見房窒傳导阻滞,其中68次为P-R间期延长。作...

1.本文报告成人急性风湿热366例,經住院观察的急性发作共415次,其中102次診断为初发,313次为复发。发作見于已有慢性心瓣缺损者計184例(218次发作),无心瓣缺损証据者182例(197次发作)。对发病季节、与溶血性鏈球菌感染的关系、临床表現、实验室发見、病程及病死率等作了分析。重点討論了本病的診断问題。 2.风湿热在春冬二季的发病率較高,41%的风湿发作前有咽痛,58.6%的风湿发作时咽部尚有炎症表現,仅24.7%的风湿发作前后均无咽炎的証据。約有80%发作中抗鏈球菌溶血素“O”滴定度在250单位以上。以上数字有力地說明了风湿热和鏈球菌感染之间的密切关系。 3.临床表現中以关节炎最为常見,发生率为55.7%,仅有关节酸痛的有30%。已有慢性心瓣缺损的病例中仅37.6%有关节炎,其发生率远低于无慢性心瓣缺损的病例(75.6%)。 4.心炎見于49.9%的发作中,其临床表現有时颇不明显。仅在心电图檢查中发見者有41例,占所有經过心电图檢查的心炎病例的29%。由此可見心电图检查对診断心炎的独特价值。 5.在曾作心电图檢查的250次发作中有82次(32.8%)发見房窒傳导阻滞,其中68次为P-R间期延长。作者等认为,P-R间期延长或更高度的房室傳导阻滞,若发見于有鏈球菌感染之后的年青患者,应作为急性风湿性心炎的診断依据之一。 6.在已有慢性心瓣病的病例中,有38.5%得根据Jones氏診断标准中的几項次要表現而診断为风湿活动。 7.366例中58.5%有风湿热的复发,其中半数发生子初发以后的第一年內。住院期的当时病死率为6.5%。

Chromosome analysis of metaphases from bone marrow cells or cul-tured peripheral blood lymphocytes of 15 patients with blood disorderswas carried out. The final diagnoses of 12 patients were confirmed aschronic myeloid leukemia(CML). The clinical diagnoses of another 2 pa-tients were acute myeloid leukemia(AML), and the other 1 was secondarypolycythemia. Cytogenetically, the Ph~1 chromosomes were found among 11 of 12 pa-tients with CML, the mean of Ph~1 positive cells was 72.3%. The presenceof Ph~1 chromosomes...

Chromosome analysis of metaphases from bone marrow cells or cul-tured peripheral blood lymphocytes of 15 patients with blood disorderswas carried out. The final diagnoses of 12 patients were confirmed aschronic myeloid leukemia(CML). The clinical diagnoses of another 2 pa-tients were acute myeloid leukemia(AML), and the other 1 was secondarypolycythemia. Cytogenetically, the Ph~1 chromosomes were found among 11 of 12 pa-tients with CML, the mean of Ph~1 positive cells was 72.3%. The presenceof Ph~1 chromosomes in 2 cases with AML was emphasized and their diag-noses were discussed in detail. The percentage of Ph~1 positive cells in thecase of so called secondary polycythemia was 69.4%, the revised diagno-sis of this case was more likely to be polycythemia vera.

对15例血液病患者进行了骨髓或外周血培养细胞的染色体观察。15例中12例临床确诊为慢性粒细胞白血病,2例诊断为急性粒细胞白血病,1例为继发性红细胞增生症。在12例慢性粒细胞白血病中,11例Ph~1染色体为阳性(阳性率平均为72.3%),1例为Ph~1阴性;2例急性粒细胞白血病患者的骨髓中期分裂细胞具Ph~1染色体者分别占1/4及1/5,其中1例还发现微小体;1例继发性红细胞增生症患者,70%的骨髓中期分裂细胞为Ph~1染色体阳性,并发现染色体碎裂细胞。

Karyotypes were studied by routine Giemsa technique in 3 patients(No.1, No.2 and No.3) with CGL. The examination was made duringblast crisis in 2 patients, No.1 and No.2, and before blastic stage inNo.2 and No.3. In all of them, Ph~1 chromosome was observed, theywere, therefore, Ph~1 positive CGL. During blastic crisis, 53% of thecells were double Ph~1 hyperdiploid in patient No.2 and the majority ofthe supernumerary chromosomes being A_3 ; patient No.1 was hypodi-ploid. Before the acute transformation, patient...

Karyotypes were studied by routine Giemsa technique in 3 patients(No.1, No.2 and No.3) with CGL. The examination was made duringblast crisis in 2 patients, No.1 and No.2, and before blastic stage inNo.2 and No.3. In all of them, Ph~1 chromosome was observed, theywere, therefore, Ph~1 positive CGL. During blastic crisis, 53% of thecells were double Ph~1 hyperdiploid in patient No.2 and the majority ofthe supernumerary chromosomes being A_3 ; patient No.1 was hypodi-ploid. Before the acute transformation, patient No.2 and No.3 had afew cells with abnormal karyotype, but many cells maintained in latemetaphase. The possible significance of these findings has been discus-sed.

作者观察了两例慢粒急变和一例急变前患者的染色体变化。发现它们均为Ph~1阳性型慢粒。急变前即有少许细胞含异常染色体,较多细胞处于晚中期阶段。急变时1例有较多的含2个Ph~1的超二倍体,超出的多为3号染色体;另一例异常细胞为亚二倍体。

 
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