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钙通道     
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  calcium channel
     Calcium channel blockade and anti-free-radical actions of panaxadiol saponins Rb_1, Rb_2,Rb_3, R_c, and R_d
     人参二醇组皂苷Rb_1,Rb_2,Rb_3,R_c和R_d的钙通道阻滞作用和抗自由基作用(英文)
短句来源
     Effect of 6,7-dimethoxycoumarin on α_1-R,H_1-R,M_3-R and calcium channel
     6,7二甲氧基香豆素对α_1受体、H_1受体、M_3受体和钙通道作用
短句来源
     CAP 25 nmol/L shifted the steady-state activation curve ofICa-Lto the left and changed half activation potential (V0.5) from (-20.76±2.0) mV to (-26.71±2.0) mV (P<0.05), indicating that low-dose CAP may modify the voltage-dependent activation of calcium channel.
     CAP 25 nmol/L可明显使稳态激活曲线左移,激活中点电压(V0.5)由-20.76±2.0mV变至-26.71±3.0mV(P<0.05),表明低浓度CAP改变了钙通道激活的电压依赖性。
短句来源
     The effect of CACNA1H gene G773D mutation on calcium channel function
     CACNA1H基因G773D突变对钙通道功能的影响
短句来源
     A Study on L Type Calcium Channel, Ca 2+ Handling and Na +/Ca 2+ Exchange Function of Infarcted Myocardial Cells
     心肌梗塞细胞L型钙通道、钙运作(Ca~(2+)handling)及钠/钙交换功能研究
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  calcium channels
     The expression of voltage-gated calcium channels α1 subunit in mouse islets was significantly decreased to 0.792±(0.078) of that in control conditions (P<0.01,n=5).
     木黄酮处理12h后,小鼠胰岛中电压依赖性钙通道的α1亚单位的表达明显减少,降低为对照组的0.792±0.078(P<0.01,n=5)。
短句来源
     Effects of TGF-β_1 and PDGF antibody on L-type calcium channels in cultured hepatic stellate cells
     TGF-β_1抗体和PDGF抗体对肝星状细胞L型钙通道的影响
短句来源
     Effects of IQ 23 on calcium channels in guinea pig ventricular myocytes and the xenogeneic calcium channel α 1 subunit expressed in CHO H 10 cells 1
     IQ_(23)对豚鼠心室肌细胞钙通道和CHO H_(10)细胞异源表达的钙通道α_1亚单位的作用
短句来源
     L-typevoltage-gated calcium channels (L-VGCCs) consist with alC (D) subunit and secondary subunit.
     中枢神经系统L-型电压门控钙通道(L-type voltage-gated calcium channels,L-VGCCs)由α1C(D)亚基和辅助亚基组成。
短句来源
     And the coexpression of α1 D and α1 E demonstrate the presence of L-type and R-type calcium channels in mammalian spiral ganglion cells.
     α1D和α1E亚单位的共表达证明在哺乳动物的螺旋神经节细胞中有L型和R型电压依赖性钙通道
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  calcium current
     Studies on Changes of Delayed Rectifier Potassium Current(I_k) and L-type Calcium Current (I_(Ca,L)) During Ischemic Preconditioning in Guinea Pig Ventricular Myocytes
     豚鼠心室肌细胞膜延迟整流钾通道电流(I_k)及L型钙通道电流(I_(Ca,L))在缺血预适应过程中的变化的实验研究
短句来源
     CCK-8 REVERSES THE INHIBITORY EFFECT OF k-OPIOID RECEPTOR AGONIST U50488H ON CALCIUM CURRENT IN RAT DORSAL ROOT GANGLION NEURON
     CCK—8翻转k-受体激动剂U50488H对急性分离大鼠背根神经节神经元上钙通道的抑制效应
短句来源
     Effects of 17β-Estradiol on Action Potential and L-Type Calcium Current in Guinea Pig Ventricular Myocytes
     17β-雌二醇对豚鼠心室肌细胞动作电位及L型钙通道电流的影响
短句来源
     Dip 3 μmol/L markedly shifted the steady-state inactivation curve of ICa-L to the left, and accelerated the voltage-dependent steady-state inactivation of calcium current.
     Dip3μmol/L可明显使钙电流稳态失活曲线左移,加速钙通道电压依赖性稳态失活。
短句来源
     10 and 100 μmol/L amiloride depressed amplitude of L-type calcium current, but did not change the shape of its I-V curve.
     阿米洛利在 10~ 10 0 μmol/L范围内抑制L型及T型钙通道电流。
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  calcium-channel
     Evaluation of Calcium-channel Blockers for Prevention of Recurrent Variceal Hemorrhage in Patients with Cirrhosis
     钙通道阻滞剂预防食管静脉曲张破裂出血的评价
短句来源
     Effects of neuromuscular blocker (NMB) of atracurium (ATC) and vecuronium (VCR ) in patients on calcium - channel blocker(CCB), nifedipine, therapy were studied with Accelograph.
     观察了钙通道阻滞药(CCB)硝苯吡啶(Nif)与阿屈可林(ATC)或维库溴铵(VCR)联用对患者神经肌肉阻滞(NMB)效应的影响。
短句来源
     Cardiovascular effects of calcium-channel blocker with radionuclide ventriculography
     核素心室造影评价钙通道阻滞剂的即刻心泵功能
短句来源
     RESULTS & CONCLUSION:It is proved that calcium-channel blocker, by the use of many years in the clinic,has satisfactory result of decreasing blood pressure;
     结果与结论 :钙通道阻滞剂经过多年的临床应用 ,其降压效果已被临床接受 ;
短句来源
     Results showed that LFD had a dramatic postive inotropic effect on the isolated rats'left ventricular papillary muscle(P<0.05). This effect was not influenced by propranolol(a beta-adrenergic blocker),but verapamil(a calcium-channel blocker)obviously antagonized it.
     结果表明:该方对大鼠离体左室乳头肌有显著的正性肌力效应(P<0.05),β受体阻断剂心得安对这一效应无明显影响,钙通道阻滞剂异搏定能明显拮抗这一效应。
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  calcium channel
The addition of a calcium channel blocker verapamil and a chelating agent EGTA to inhibit Ca2+ influx from the medium eliminated the AP spike and diminished reversible alkalization of the external solution.
      
After entering into the cell through the N-type calcium channel, calcium binds to calmodulin, and triggers calcium release from intracellular calcium store by activating the caffeine-sensitive but ryan-odine-insensitive mechanism.
      
CACNA1S gene encodes the α1 subunit of the calcium channel.
      
Removing Ca2+ from the bath or using calcium channel antagonist (CdCl2, Nifedipine) greatly inhibited the [Ca2+]i increase induced by ONOO-1, suggesting that the opening of L-Ca2+ channel makes a great contribution to the [Ca2+]i increase.
      
Identification and characterization of human neuronal voltage-gated calcium channel gamma 3 subunit gene
      
更多          
  calcium channels
H2O2 has been recently shown to accelerate the overall channel opening process in voltage-dependent calcium channels in plant and animal cells.
      
Study of the activity of calcium channels that are regulated by intracellular calcium stores in mouse embryonic stem cells
      
The inhibitor of voltage-dependent calcium channels diltiazem (10 and 100 μM) decreased the rate of ovulation in Ringer solution but did not affect it in a chloride-free medium or decreased the ovulation inhibitory effect of this medium.
      
Role of Calcium Channels in Phytochrome-Mediated Regulation of Gravitropic Response
      
The effect of the inhibitors of calcium channels on red-light (R)-mediated inhibition of gravitropic bending was studied in excised wheat (Triticum aestivumL.) coleoptiles.
      
更多          
  calcium current
Using isolation cell procedure and whole cell recording, we found that 10 μM quinidine (34.77±6.5%, n=5) and 0.5 μM flecainide (50.46±6.2%, n=4) decrease calcium current in human atrium.
      
It is concluded that, at therapeutical concentrations, quinidine and flecainide modify the action potential plateau phase in a different manner, which is not only related to the calcium current decrease.
      
It is implied that this effect is mediated via ICa, the inward calcium current, which makes a larger than normal contribution to direct contractile activation in hypothermic myocardium.
      
Influence of phorbol esters on contractile force, action potential and calcium current of isolated guinea-pig heart tissues
      
In isolated ventricular cardiomyocytes the inward calcium current was halved by either 1 μmol/l PDB or 10 μmol/l PMA.
      
更多          
  calcium-channel
Dual Effect of Inorganic Calcium-Channel Blockers on Contraction of Smooth Muscles of the Frog
      
Treatments with alternative techniques like DCA, TEC and ELCA as well as phamacological attempts like GP IIb/IIIA inhibitors, vasodilators and calcium-channel blockers do not improve outcome.
      
Conclusions The alpha-blocker terazosin is as effective as atenolol when combined with either an ACE inhibitor or a calcium-channel blocker as a part of a multidrug regimen to achieve sufficient blood pressure control.
      
It has been shown that various calcium-channel antagonists may delay plaque formation in animal models.
      
On balance, the articles reviewed prove that dihydropyridine calcium-channel blockers score particularly well in the prevention of cardiovascular complications in diabetic patients with hypertension.
      
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