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Controlled by a high-resolution piezoelectric driver designed for scanning probe microscopy, the distance between the micropipette point and the polymer surface was kept to a few tens of nm.
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Penetration of cells membrane by the piezoelectric driver
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We have improved the conventional design by introducing a multilayer piezoelectric driver and a Si solid-state detector in place of the conventional elements.
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The piezoelectric driver can work at high frequencies (0.1-2 kHz) and the new set up can be assembled in a very compact way (a cylinder of approximate 15 cm length and 2 cm diameter).
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By increasing the piezoelectric driver voltage to 4 volts, jitceased and no improvements werenotedat voltages.
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