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孕期变化
相关语句
  相似匹配句对
     Change
     变化
短句来源
     The echo and flow dynamic change of fetal lung during pregnancy
     孕期胎肺回声和血液动力学变化
短句来源
     Change of serum compound W in normal pregnant women
     正常妇女孕期血清W物质的变化
短句来源
     Change of the interpersonal relationships ;
     人际关系的变化;
     strengthen pregnant health care;
     加强孕期保健;
短句来源
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In Kung ding albino pregnant mouse uterus,we found a specific kind of cells,called Granulated Metrial Gland(G0G)cells.These cells were roughly circular with relatively pale staining cytoplasm,contbaining numerous diastase resistant PAS positive granules.GMG cells were distributed in the decidua basalis and metrial gland cells area(that was called the mesometrial triangle in non pregnant uterus).GMG cells were not found in virgin uteri. They appeared after pregnancy,increased in number after implantation,reduced...

In Kung ding albino pregnant mouse uterus,we found a specific kind of cells,called Granulated Metrial Gland(G0G)cells.These cells were roughly circular with relatively pale staining cytoplasm,contbaining numerous diastase resistant PAS positive granules.GMG cells were distributed in the decidua basalis and metrial gland cells area(that was called the mesometrial triangle in non pregnant uterus).GMG cells were not found in virgin uteri. They appeared after pregnancy,increased in number after implantation,reduced in the last few days of gestation,and disappeared after delivery.The GMG cells appeared only in pregnant uteri.They possessed close relationship with pregnancy.

在昆明种小白鼠的子宫内证实有一类具有特殊性的细胞一颗粒子宫腺细胞。该细胞具有如下特点:1.体积大,胞质内含耐淀粉酶消化的PAS阳性颗粒;2.分布位置特殊,位于子宫系膜三角区和基蜕膜;3.具有孕期变化,孕早期出现,中期最多,后期减少,产后消失。该类细胞的出现及消失与妊娠过程同步,故作者认为其与妊娠关系密切。

Objective To explore the changes in bone mineral density and biochemical markers of bone metabolism in normal pregnancy. Methods Bone mineral density(BMD) and serum concentrations of calcium(Ca), phosphorous(P), alkaline phosphatase(ALP), osteocalcin(BGP) were measured in 63 normal manual working pregnant women and 21 normal fertile mental working women. Among the pregnant women, 21 were studied during the first trimester (5~13 weeks), 21 during the second trimester (>13~28 weeks) and 21 during the third trimester(>28...

Objective To explore the changes in bone mineral density and biochemical markers of bone metabolism in normal pregnancy. Methods Bone mineral density(BMD) and serum concentrations of calcium(Ca), phosphorous(P), alkaline phosphatase(ALP), osteocalcin(BGP) were measured in 63 normal manual working pregnant women and 21 normal fertile mental working women. Among the pregnant women, 21 were studied during the first trimester (5~13 weeks), 21 during the second trimester (>13~28 weeks) and 21 during the third trimester(>28 weeks). In addition fasting urinary hydroxyproline/creatinine (Hp/Cr) and calcium/creatinine (Ca/Cr) ratio were measured in these subjects. Results No significant differences in BMD and serum concentrations of Ca and P were found during pregnancy ( P >0 05). Urinary Hp/Cr and Ca/Cr ratio tended to rise through pregnancy to term. But there was no significant difference among 4 groups( P >0 05). Serum concentrations of ALP and BGP in first and second trimesters were similar to those in nonpregnant wonen, but they rose rapidly in third trimester. There was significant difference between the third trimester group and the other groups ( P <0 05). Conclusion Pregnancy had not a significant effect on BMD. Changes in serum and urine markers of bone formation and resorption suggest that bone turnover may be inhabited in first and second trimesters, but significantly increased in third trimester.

目的 探讨妊娠期骨密度和骨代谢的变化。方法 对合肥市健康脑力劳动孕妇63例和非孕对照组21例分别测定桡骨骨密度(BMD)、血钙(Ca)、磷(P)、碱性磷酸酶(ALP)、骨钙素(BGP)以及尿羟脯氨酸/肌酐(HP/Cr)和尿钙/肌酐(Ca/Cr)比值。结果 ①孕期桡骨骨密度无明显变化,与非孕对照组比较有下降,但差异无显著性(P>005);②血Ca和P浓度孕期与对照组比较,差异无显著性(P>005);③血ALP和BGP在晚孕组明显升高,与非孕对照组和早、中孕组比较差异有显著性(P均<005);④尿HP/Cr和Ca/Cr在孕期有随孕周增加而升高的趋势,但各孕组间及与对照组比较差异无显著性(P均>005)。结论 妊娠期骨密度有下降,但无明显改变。而骨代谢生化指标在晚孕期变化明显,显示晚孕期骨转换率增加。

Objective To investigate the fluorescence quantitative PCR (FQ-PCR) based on TaqMan-MGB( Minor Groove Binder) technique for quantification of fetal DNA in maternal plasma and its variation during pregnancy. Methods Maternal DNA extracted from 237 plasma samples obtained from 30 pregnant women (5-40 gestational weeks and post delivery). The TaqMan-MGB probe and SRY primers were designed to amplify the SRY gene sequence of Y chromosome in maternal plasma by FQ-PCR. Results This system was sensitive enough to detect...

Objective To investigate the fluorescence quantitative PCR (FQ-PCR) based on TaqMan-MGB( Minor Groove Binder) technique for quantification of fetal DNA in maternal plasma and its variation during pregnancy. Methods Maternal DNA extracted from 237 plasma samples obtained from 30 pregnant women (5-40 gestational weeks and post delivery). The TaqMan-MGB probe and SRY primers were designed to amplify the SRY gene sequence of Y chromosome in maternal plasma by FQ-PCR. Results This system was sensitive enough to detect a male DNA among 20 000 female DNA. Fetal DNA can be detected in maternal plasma as early as 6+6 weeks of gestation and increased with the pregnant progress with the peak level at the third trimester. Between 24- 48 h after delivery, the SRY gene was negative in maternal plasma. The percentage of fetal DNA concentration in maternal total plasma DNA was 4. 88% in the first trimester, 6. 10% in the second and 4. 77% in the third trimester. The SRY positive signal was obtained from samples of 13 women bearing male fetuses and no signal was detected for all of the 17 women bearing female fetuses. Conclusions The FQ-PCR for quantification of fetal DNA in maternal plasma is highly sensitive, specific and reliable. Fetal DNA does present in maternal plasma at a higher concentraton. FQ-PCR may be useful in nonin-vasive prenatal diagnosis.

目的探讨荧光定量PCR(fluorescenecequantitativePCR,FQ-PCR)方法检测孕妇血浆中胎儿DNA的可行性,探讨胎儿DNA在孕妇血浆中的含量及其在孕期的变化规律。方法以胎儿SRY基因序列作为胎儿DNA在孕妇血浆中的标志,应用荧光MGB(MinorGrooveBinder)探针实时定量PCR方法连续测定30例孕妇在不同孕期和产后共237份血浆标本中胎儿DNA的含量。结果使用该方法最低可检测到20000个女性DNA中的一个男性DNA。孕妇血浆中最早检出SRY序列的时间为孕6+6周。孕8周起,所有怀男胎孕妇的标本中均可检出SRY序列,其含量随着妊娠的进展而增高,在晚期妊娠达高峰,产后24-48h血浆中SRY序列检测均为阴性。胎儿DNA在孕妇血浆总DNA含量中的相对浓度分别为孕早期4.88%、孕中期6.10%、孕晚期4.77%。全部实验无假阳性和假阴性出现。结论FQ-PCR方法是一种灵敏度和准确性高,特异性强的定量检测孕妇血浆中胎儿游离DNA的方法,孕妇血浆中存在高浓度的胎儿DNA,可用于无创伤性产前基因诊断。

 
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