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重组cho细胞乙肝疫苗
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  “重组(cho细胞)乙肝疫苗”译为未确定词的双语例句
     The residual DNA in purified rabies vaccine, hepatitis B vaccine made by recombinant DNA techniques in CHO cell, Heamorrhagic Fever with Renal Syndrome (HFRS) vaccine and shigella polysaccharide vaccine were detected by labeled probe of digoxigenin.
     用地高辛标记探针检测由传代细胞系生产的人用精制狂犬病疫苗、重组 (CHO细胞 )乙肝疫苗、出血热疫苗及痢疾多糖结合疫苗原液中残余DNA含量。
短句来源
     For understanding the long-term immune efficacy of hepatitis B(HB)vaccine from 1986~1999, the newborns in Wuxing town of Zhengding County of Hebei Province integrated with EPI Program were universally vaccinated by 0,1,6 month schedule after their birth.
     观察了正定县吴兴乡新生儿实施乙型肝炎 (乙肝 )疫苗普种后 14年的免疫学效果。 该乡自 1986年开始对所有新生儿结合农村计划免疫 ,按 0、1、6个月程序接种 3剂乙肝疫苗 ,在 1986~ 1996年用血源乙肝疫苗 ,1997~ 1999年用重组 (CHO细胞 )乙肝疫苗。
短句来源
     The anti-HBs positive rates and GMT of CHO recombinant vaccine were higher than those of recombinant yeast-derived vaccine. GMT induced by 10μg CHO recombinant vaccine was obviously higher than that induced by 10μg recombinant yeast-derived vaccine,but the anti-HBs positive rates had no significant differentce.
     重组(CHO细胞)乙肝疫苗抗 HBs阳性率和GMT高于重组(酵母)乙肝疫苗,重组(CHO细胞)乙肝疫苗10 μg诱导的抗 HBsGMT显著优于10 μg重组(酶母)乙肝疫苗,但抗HBs阳性率差异无显著的统计学意义。
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  相似匹配句对
     Objective To explore the possibility of astragalus polysaccharide(APS)used as an adjuvant of recombinant HB vaccine prepared with CHO cells.
     目的 探讨黄芪多糖(APS)作为重组CHO细胞乙肝疫苗免疫佐剂的可行性。
短句来源
     Study on Stability of Recombinant CHO Cell HB Vaccine
     重组(CHO细胞)乙型肝炎疫苗稳定性的研究
短句来源
     Study on High-level Expression of Recombinant Hepatitis B Surface Antigen in CHO Cell
     重组CHO细胞高效表达乙肝表面抗原的研究
短句来源
     Recombinant Hepatitis B (CHO-derived) Surface Antigen Vaccine and Its Immune Effects
     重组乙型肝炎疫苗(CHO细胞)及其应用
短句来源
     Large-Scale Cultivation of CHO Cells Produsing HBV Vaccine Using Fibral-cel Carrier
     乙肝疫苗基因工程CHO细胞的新型载体的大量培养
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Objective To explore the possibility of astragalus polysaccharide(APS)used as an adjuvant of recombinant HB vaccine prepared with CHO cells. Methods Mix APS with recombinant HBsAg( CHO cell) and carry out toxicity, allergy and efficacy tests in animals. Results The APS showed mild toxicity and no allergic reaction. The serum and -HBs positive conversion rate of the animals immunized with the vaccine using APS as adjuvant was significantly higher than that using Al(OH)3. Conclusion APS is a potential adjuvant...

Objective To explore the possibility of astragalus polysaccharide(APS)used as an adjuvant of recombinant HB vaccine prepared with CHO cells. Methods Mix APS with recombinant HBsAg( CHO cell) and carry out toxicity, allergy and efficacy tests in animals. Results The APS showed mild toxicity and no allergic reaction. The serum and -HBs positive conversion rate of the animals immunized with the vaccine using APS as adjuvant was significantly higher than that using Al(OH)3. Conclusion APS is a potential adjuvant of HB vaccine.

目的 探讨黄芪多糖(APS)作为重组(CHO细胞)乙肝疫苗免疫佐剂的可行性。方法APS与重组(CHO细胞)乙肝病毒表面抗原(HBsAg)混合制成疫苗,进行了动物毒性试验、过敏试验及效力试验。结果 该佐剂毒性轻微,无过敏反应,同一剂量组动物血清抗-HBs阳转率高于Al(OH)3对照组。结论APS是一种很有潜力的疫苗佐剂。

The residual DNA in purified rabies vaccine, hepatitis B vaccine made by recombinant DNA techniques in CHO cell, Heamorrhagic Fever with Renal Syndrome (HFRS) vaccine and shigella polysaccharide vaccine were detected by labeled probe of digoxigenin.The results showed that the method has a high sensitivity and specificity.It is suitable for the detection of residual DNA in the biological products.

用地高辛标记探针检测由传代细胞系生产的人用精制狂犬病疫苗、重组 (CHO细胞 )乙肝疫苗、出血热疫苗及痢疾多糖结合疫苗原液中残余DNA含量。结果表明 ,该方法特异性强 ,灵敏度高 ,可用于上述生物制品中残余DNA含量的检测

For understanding the long-term immune efficacy of hepatitis B(HB)vaccine from 1986~1999, the newborns in Wuxing town of Zhengding County of Hebei Province integrated with EPI Program were universally vaccinated by 0,1,6 month schedule after their birth.The plasma-derived HB vaccine was used in 1986~1996,while the CHO cell recombinant HB vaccine was used in 1997~1999. The vaccine coverage rate were 87.16% during 1986~1999 and 93.74% during 1997~1999....

For understanding the long-term immune efficacy of hepatitis B(HB)vaccine from 1986~1999, the newborns in Wuxing town of Zhengding County of Hebei Province integrated with EPI Program were universally vaccinated by 0,1,6 month schedule after their birth.The plasma-derived HB vaccine was used in 1986~1996,while the CHO cell recombinant HB vaccine was used in 1997~1999. The vaccine coverage rate were 87.16% during 1986~1999 and 93.74% during 1997~1999. The serum samples were collected in 1999 to detect HBsAg,anti-HBs and anti-HBc by SPRIA kit and compared them with that of the children of the same age and the same place before immunization.The results showed that after universal immunization of HB vaccine,the anti-HBs protective positive rate in 1~14 year old children was 94.7%~10.27%,the GMT(S/N value)was 76.72~5.62 which gradually decreased following growth of age,level of HBsAg did not rise before 10 years old.The total positive rate of HBsAg in 1~14 year old children was 1.27%,the protective rate 87.9% when compared with 10.5% in children of the same age and same town before immunization(95%IC 83.18%~93.38%). The positive rate of anti-HBc was 2.28%, it decreased about 93.56% as compared with in children of the same age and same town before immunization,and a rising ten dency in 10~14 year old children about 4.59%~2.74% was noticed.The data above indicated that the immune efficacy of HB vaccine within 10 years is satisfactory,the supplementary immunization is not necessary within this period

观察了正定县吴兴乡新生儿实施乙型肝炎 (乙肝 )疫苗普种后 14年的免疫学效果。该乡自 1986年开始对所有新生儿结合农村计划免疫 ,按 0、1、6个月程序接种 3剂乙肝疫苗 ,在 1986~ 1996年用血源乙肝疫苗 ,1997~ 1999年用重组 (CHO细胞 )乙肝疫苗。全程接种率 1986~ 1996年为 87 16 %,1997~ 1999年为 93 74%。于 1999年普查采血 ,用固相放射免疫试剂检测乙肝病毒表面抗原 (HBsAg)与抗体 (抗 -HBs)以及乙肝病毒核心抗体 (抗 -HBc) ,并与本地免疫前同龄儿童HBsAg阳性率进行比较 ,计算乙肝疫苗的免疫效果。结果显示 :乙肝疫苗免疫后 ,1~ 14岁儿童保护性抗 -HBs阳性率为 94 74%~ 10 2 7%,S/N值几何平均滴度 (GMT)为 76 72~ 5 6 2 ,随着免疫年限的延长而逐渐降低 ;HBsAg在 10岁以前无升高趋势 ,1~ 14岁儿童的HBsAg总阳性率 1 2 7%,与免疫前同龄儿童的 10 5 %相比 ,保护率为 87 9%(95 %可信限 83 18%~ 93 38%)。抗 -HBc阳性率为 ...

观察了正定县吴兴乡新生儿实施乙型肝炎 (乙肝 )疫苗普种后 14年的免疫学效果。该乡自 1986年开始对所有新生儿结合农村计划免疫 ,按 0、1、6个月程序接种 3剂乙肝疫苗 ,在 1986~ 1996年用血源乙肝疫苗 ,1997~ 1999年用重组 (CHO细胞 )乙肝疫苗。全程接种率 1986~ 1996年为 87 16 %,1997~ 1999年为 93 74%。于 1999年普查采血 ,用固相放射免疫试剂检测乙肝病毒表面抗原 (HBsAg)与抗体 (抗 -HBs)以及乙肝病毒核心抗体 (抗 -HBc) ,并与本地免疫前同龄儿童HBsAg阳性率进行比较 ,计算乙肝疫苗的免疫效果。结果显示 :乙肝疫苗免疫后 ,1~ 14岁儿童保护性抗 -HBs阳性率为 94 74%~ 10 2 7%,S/N值几何平均滴度 (GMT)为 76 72~ 5 6 2 ,随着免疫年限的延长而逐渐降低 ;HBsAg在 10岁以前无升高趋势 ,1~ 14岁儿童的HBsAg总阳性率 1 2 7%,与免疫前同龄儿童的 10 5 %相比 ,保护率为 87 9%(95 %可信限 83 18%~ 93 38%)。抗 -HBc阳性率为 2 2 6 %,与免疫前同龄儿童的 35 1%相比 ,降低了 93 5 6 %。新生儿乙肝疫苗免疫后随年龄的增长保护性抗体水平逐年下降 ,HBsAg阳性率 10~ 14岁开始出现升高趋势 ,而在 10岁以前未见升高趋势 ,说明免疫后 10年间效果良好 ,无需加强免疫。

 
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