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   免疫诱导 在 基础医学 分类中 的翻译结果: 查询用时:0.232秒
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免疫诱导
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  “免疫诱导”译为未确定词的双语例句
    Induction of the Anti Idiotypic Antibody Bearing Internal Image of 9 1C3 Molecule by Gene Immunization
    基因免疫诱导9.1C3分子内影像类抗独特型抗体的产生
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    To investigate the immune effects of combined DNA immunization of human interleukin 12 and Mycobacterium tuberculosis ESAT-6 antigen.
    人白细胞介素12(IL-12)与结核分枝杆菌免疫优势抗原ESAT-6真核表达质粒联合基因免疫,诱导免疫应答效果观察。
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    INDUCING ANTIBODY RESPONSE AGAINST E2 GLYCOPROTEIN OF HEPATITIS C VIRUS IN BALB/c MICE BY PLASMID DNA BASED IMMUNIZATION
    基因免疫诱导小鼠产生抗丙型肝炎病毒E2糖蛋白抗体
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    T cell vaccination induces regulatory T cell response in BALB/c mice
    卵清白蛋白特异性T细胞免疫诱导BALB/c小鼠的调节性免疫应答
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    Humoral immune responses in mice to the recombinant expressed protein and the nucleic acid vaccine of circumsporozoite protein gene of Plasmodium falciparum
    恶性疟原虫CSP基因重组蛋白及DNA免疫诱导小鼠体液免疫应答比较
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T lymphocyte subpopulation from the

以鼠伤寒杆菌G30株为对照,应用间接免疫荧光法检测了痢疾杆菌福氏2a经口服及腹腔免疫后,小鼠派伊尔氏(PP)节结、肠系膜淋巴结(MLN)及脾脏(SPt)中L3T4~+、Lyt2~+T细胞亚群的变化;并以MTT比色法测定了ConA诱导的淋巴细胞增殖反应。实验发现:无论是口服还是腹腔途径,这两种细菌都诱导出基本相似的T淋巴细胞反应,即L3T4亚群在PP及MLN中均有显著升高,而Lyt2亚群均无明显变化;口服途径仅PP淋巴细胞的增殖反应有明显升高,腹腔途径主要为MLN出现淋巴细胞显著的增殖反应。提示:在痢疾菌感染免疫中以L3T4亚群起主要作用;PP作为粘膜免疫的诱导部位;经口途径主要诱导肠道局部淋巴细胞的免疫应答,经腹腔途径虽能诱导多部位免疫应答但有否抗粘膜感染保护作用尚待研究。

Mice of Kunming strain were infected with Schistosoma japonicum cercariae previously incubated with various concentrations of acridine mutagen ICR-170 for different time durations. At 6 weeks after infection, the mice were autopsied. The results showed that 24 out of 28(85. 7%) adult female worms had deformed or lacked ovaries and vitelline glands when the cercariae were treated with the agent at a concentration of 10μg/ml and incubated at 30. 5℃ for 30min. No apparnet changes were observed in the male worms...

Mice of Kunming strain were infected with Schistosoma japonicum cercariae previously incubated with various concentrations of acridine mutagen ICR-170 for different time durations. At 6 weeks after infection, the mice were autopsied. The results showed that 24 out of 28(85. 7%) adult female worms had deformed or lacked ovaries and vitelline glands when the cercariae were treated with the agent at a concentration of 10μg/ml and incubated at 30. 5℃ for 30min. No apparnet changes were observed in the male worms inhabiting the mesenteric and portal veins with the females worms in their gynecophoral canals. The mutagenized female schistosomes obtained from the present experiment might be served as another form of attenuated worms for the induction of protective immunity.

吖啶诱变剂ICR-170和血吸虫尾蚴温育(30.5℃)后,经皮感染小鼠,6wk解剖,检视成虫发育情况,发现10μg/ml30min组28条雌虫中,发生卵巢、卵黄腺全缺或畸变者24条,诱变率高达85.7%;雄虫未见明显影响;所有不育的畸变雌虫仍被雄虫抱合,寄居在肠系膜静脉或肝门静脉内。本实验为进一步研究保护性免疫的诱导,提供了另一种形式的致弱虫体抗原。

The morphologic and distributive characterizations of intraepithelial lymphocyte (IEL) in ileum and the dome area of Peyer′s patch in BALB/c mice which took salmonella typhi were observed by electron microscopy and immunohistochemistry, in order to inquire about the role of IEL in the mucosal immune response under antigen inducement. By immunohistochemistry the results suggest that there are two types lymphocytes, T and B in IEL of ileum and the dome area, and B lymphocytes are more obvious. Under electron microscope,...

The morphologic and distributive characterizations of intraepithelial lymphocyte (IEL) in ileum and the dome area of Peyer′s patch in BALB/c mice which took salmonella typhi were observed by electron microscopy and immunohistochemistry, in order to inquire about the role of IEL in the mucosal immune response under antigen inducement. By immunohistochemistry the results suggest that there are two types lymphocytes, T and B in IEL of ileum and the dome area, and B lymphocytes are more obvious. Under electron microscope, IEL constitutes small and moderate lymphocytes, and there are two types of morphology in the moderate lymphocytes in IEL. One type has fewer cell organelles, and there are tight contact among these cells and microvilli; the other has plentiful organelles and distended endoplasmic reticulum. Some IEL were observed in epithelium, and others in the intercellular space of epithelia. Therefore, intestinal epithelia is not only the effector site but inductive site of the mucosal immunity as well. These suggest that the bacteria may induce lymphocytes to migrate into the epithelia of intestine and dome area, and the epithelia of dome area tend to take antigen more easily than that of intestine.

采用免疫组织化学和电镜方法,观察了BALB/c小鼠灌服伤寒杆菌后回肠及集合淋巴小结圆顶区肠上皮内淋巴细胞(intraepitheliallymphocyte,IEL)的形态和分布特征,以探讨IEL在抗原诱导下的粘膜免疫应答中的作用。经免疫组织化学方法证实灌服伤寒杆菌后回肠及集合淋巴小结圆顶区肠上皮内含B和T两种淋巴细胞,以B淋巴细胞为主;电镜下可见上皮内淋巴细胞主要由小和中等淋巴细胞组成,且后者有两种形态。一种细胞器较少,与上皮微绒毛之间有紧密接触。另一种细胞器丰富,内质网呈扩张状态。同时观察到IEL有的位于上皮细胞内,有的位于相邻的上皮细胞间隙内。本研究提示,小肠上皮不仅为粘膜免疫效应部位,而且也是免疫诱导部位。提示伤寒杆菌能诱导淋巴细胞向小肠上皮和圆顶区上皮迁移,且圆顶区上皮比小肠上皮更易接受抗原刺激。

 
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