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气道功能     
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  airway function
     The resultsshowed: (1) There was no significant diffe-rence in VC/VC_(pr), FEV_(1.0)%, MVV/MVV_(pr),V_(50)/H, V_(25)/H and the rates of abnormal anddoubtful abnormal small airway function(SAF) between two groups.
     结果表明:(1)两组VC/VC_(PR)、FEV_(1.0)%、MVV/MVV_(PR)、V_(50)/H、V_(25)/H、小气道功能异常率及可疑异常率均无显著性差异。
短句来源
     _(15), (?) _(50) and FEP as indices of small airway function in addition to VC, MVV, FEV_1% and MMEF.
     认为肺功能检查项目,除VC、MVV、FEV_1%和MMEF外,有条件应增加V_(50)、V_(25)和FEP等小气道功能检查;
短句来源
     In the tests for small airway function, SBN2 was the most sensitive in all indexes, and the next were CC/TLC% and (?) 50/H.
     资料分析表明,在检出小气道功能异常方面SBN_2最敏感,其次是CC/TLC%和V_(50)/H。
短句来源
     Effects of 21d-6°Head Down Bed rest on Pulmonary Gas Distribution and Little Airway Function.
     21d-6°头低位卧床对肺气体分布和小气道功能影响的实验观察
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     Results Small airway function in the patients with lung cancer significantly declined. V_(25)% and V_(50)% were <80%.
     结果肺癌组中小气道功能指标明显降低,V25%、V50%均<80%。
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  airway functions
     Therefore, the convex type, the prolongation of MTT 45%~55% and MTT 70% 80% , and the decrease of ·V 50 and ·V 25 should all be used as sensitive indices for testing small airway functions.
     因而凸型F-V曲线、MTT45%~55%及MTT70%~80%延长、·V50、·V25下降都是检查小气道功能的敏感指标。
短句来源
     A comparative study of the determinations of small airway functions
     小气道功能测定的比较研究
短句来源
     Thereafter 2 years, the rate of natural decrement in small airway functions were lower than that of the contcol (P<0.05).
     部分人员随诊2年,其小气道功能自然下降率明显低于对照组(P<0.05)。
短句来源
     Conclusion In comparison with MEFV curve, ·V FRC and ·V FRC/FVC are also sensitive to small airway functions, and the degree of decrease in their values can reflect the severity of disease.
     结论与 MEFV曲线相比 ,·VFRC、·VF RC/ FVC仍然是检查小气道功能的敏感指标 ,其下降的程度可反映疾病严重的程度。
短句来源
     To evaluate the clinical significance of maximal midexpiratory time(MET) in testing small airway functions for smokers,the routine ventilatory functions,MET and F V curve configurations were studied in 116 passive and light,heavy active smokers.
     为评价最大呼气中段时间(MET)对检查吸烟者小气道功能的临床意义,我们对116 例被动吸烟者和轻、重度主动吸烟者的常规肺通气功能、MET和F-V曲线形状进行了探讨。
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  airways function
     It also proves that in these patients, the rates of abnormality in large airways function(LAF) and SAF are 23.8% and 52.3% respectively. The difference is 28.5%, P<0.01. Even in thosepatients whose LAF arenormal,the mean values of their SAF are lower than that of the control group.
     又证实在Ⅰ期矽肺病人中,大、小气道异常率分别为23.8%、52.3%,相差28.5%,P<0.01,且大气道功能正常的病人小气道功能测得值亦低于对照组。
短句来源
     STUDY ON THE SMALL AIRWAYS FUNCTION VALUES IN WORKING CAPABILITY IDENTIFICATION OF SILICOTIC PATIENTS
     几项小气道功能检测在矽肺病人劳动能力鉴定中应用的研究
短句来源
     Small airways function(SAF) in 195 cases of silicosis and 104 cases of health workers are reported.
     本文对195例矽肺病人和104例健康工人的小气道功能进行了研究。
短句来源
     Effect of Ceramic Dust on the Small Airways Function in Workers
     陶瓷尘对工人小气道功能的影响
短句来源
     The small airways function were. measured from 339 workers exposed to ceramic dust and 329 nonexposed.
     选择接触陶瓷粉尘工人339名和非接触者329名,对其小气道功能进行了测定。
短句来源
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  airway responsiveness
     To evaluate the value of measurement of pulmonary function and airway responsiveness in the diagnosis of cough variant asthma,we measured the pulmonary ventilating function,small airway function and airway responsiveness of 38 patients with cough variant asthma,normal control group and the patients with typical bronchial asthma. The results showed that pulmonary ventilating function and small ariway function in cough variant asthma group were better than those in typical bronchial asthma group;
     为探讨肺功能及气道反应性测定在诊断咳型哮喘发作中的作用,检测了38例咳型哮喘病人和具有可比性的正常人及典型支气管哮喘病人的通气功能、小气道功能及气道反应性.结果咳型哮喘组通气功能及小气道功能介于正常组和典型哮喘组之间;
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  airway function
Airway inflammation and structural airway changes can lead to this heightened airway response, but the mechanisms by which they modify airway function are still unclear.
      
Furthermore, a recent study on their role as part of the innate immune response has demonstrated that γδ T cells regulate airway function independently of αβ T cells.
      
The effect of bucindolol on the airway function of asthmatics
      
Effects of single oral doses of bisoprolol and atenolol on airway function in nonasthmatic chronic obstructive lung disease and
      
Effect of neutral endopeptidase inhibitor on airway function and bronchial responsiveness in asthmatic subjects
      
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  airway functions
The complex anatomy of the larynx is a consequence of its various airway functions.
      
Expiratory flows, averaged over pre-selected segments of the spirogram, are used in assessment of airway functions.
      
This finding suggests that the infiltration of airway smooth muscle by mast cells is associated with the disordered airway functions found in asthma.
      
  airways function
We have studied eight adult atopic asthmatic patients in a randomized double-blind, placebo-controlled, cross-over trial in order to examine the effects of the 5 HT2 antagonist ketanserin on airways function (FEV1, FVC, V50(χ), and V25(π)).
      
Blind marking scores for the 81mKr images of the asthmatic subjects related significantly to small airways function.
      
Radioaerosol abnormalities in the asthmatic subjects included excessive deposition of the radioaerosol in the central airways and related significantly to small airways function.
      
Radioaerosol abnormalities in patients with poor small airways function probably reflect (1) uneven distribution of ventilation to different regions of the lung periphery and (2) changed patterns of airflow in the bronchial tree.
      
Studies with animal models of allergic asthma have shown the effectiveness of antagonists of adhesion molecules in blocking the development of airway inflammation and changes in airways function.
      
更多          
  airway responsiveness
In this review, we describe several novel genes, including ADAM33, ADRB2, and eotaxin, that modify airway responsiveness in asthmatic patients.
      
Inhalation challenges with direct-acting stimuli histamine and methacholine are widely used to measure airway responsiveness.
      
Careful standardization is important so as to best differentiate normal from increased airway responsiveness and to permit comparison between methods.
      
Effect of one hour of passive cigarette smoking on lung function and airway responsiveness in adults and children with asthma
      
There were no significant differences in lung function and airway responsiveness between exposure to ambient air or ETS.
      
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  其他


Routine pulmonary ventilation tests. MMF. MEFV and CV are determined in 107 young adults of age 20-30. including smokers, asthmatics in remission, and the healthy control group. The sensitivity of these indices are compared in assessing the dysfunction of the small airways. It is found that in smoker group. PEFR is the most sensitive. MMF and MEFV the next. For asthmatics in remission. MMF is the most sensitive. MEFV. DN2% and CC/TLC% the next. CV/VC% is not sensitive for both groups. MEFV seems to be superior...

Routine pulmonary ventilation tests. MMF. MEFV and CV are determined in 107 young adults of age 20-30. including smokers, asthmatics in remission, and the healthy control group. The sensitivity of these indices are compared in assessing the dysfunction of the small airways. It is found that in smoker group. PEFR is the most sensitive. MMF and MEFV the next. For asthmatics in remission. MMF is the most sensitive. MEFV. DN2% and CC/TLC% the next. CV/VC% is not sensitive for both groups. MEFV seems to be superior to CV. while DN2% and MMF may also be utilized.

本文对青年人(20~30岁)健康组、吸烟组和缓解期哮喘组共107例作了常规肺通气功能,最大呼气中段流速(MMF)、最大呼气流速容量曲线(MEFV)、闭合气量(CV)的测定,并对检溯小气道功能异常的各项指标的敏感性作了比较。结果吸烟组以呼气峰流速率(PEFR)最为敏感,其次为MMF、MEFV;缓解期哮喘组以MMF最敏感,其次为MEFV、氮浓度差百分比(D_(N2)%)和闭合总量/肺总量百分比(CC/TLC%);而闭合气量/肺活量百分比(CV/VC%)不敏感。认为小气道功能检测MEFV优于CV,D_(N2)%和MMF也可作为敏感性指标。

This report presents the resultsusing a simplified method to determinethe Mean Transit Time (MTT) andPartial Mean Transit Time of smallairways (MTT_(p-s)) in 180 normalsubjects and 120 cases of Chronicobstructive pulmonary disease (COPD).The physiological factors includingage, sex, height and weight whichmight affect more or less MTT andMTT_(p-s) were analyzed, the linearregression equations closely correlatedto age formulated, and the relation-ships of MTT and MTT_(p-s) to theparameters of V_(75), V_(25), CV/VC...

This report presents the resultsusing a simplified method to determinethe Mean Transit Time (MTT) andPartial Mean Transit Time of smallairways (MTT_(p-s)) in 180 normalsubjects and 120 cases of Chronicobstructive pulmonary disease (COPD).The physiological factors includingage, sex, height and weight whichmight affect more or less MTT andMTT_(p-s) were analyzed, the linearregression equations closely correlatedto age formulated, and the relation-ships of MTT and MTT_(p-s) to theparameters of V_(75), V_(25), CV/VC etc.discussed. An analysis of the deter-mined values on 9 items of lungfunction in 120 cases of COPD showedthat MTT and MTT_(p-s) were sensitiveparameters in the diagnosis of smallairways obstruction. The ratios ofthe actual values over the predictedvalues increased progressively alongwith the severity of the airwaysobstruction and the lung diseases, andespecially that as MTT_(p-s) appeared tooffer the highest detection rate ofabnormality, it might be of practicalvalue in estimating the degrees ofobstructive emphysema. MTT_(p-s) re-flected actually the emptying rate ofthe. pulmonary slowly emptying units,expressing distribution characteristicsin mathematics estimates on the 62. 5-87.5% FVC part of the forced expira-tory curve, so MTT_(p-s) might be recom-mended as the most sensitive param-eters in detecting small airwaysobstruction.

本文报道用改良简化法和计算公式测定180例正常人和120例慢性阻塞性肺部疾病患者的平均通过时间,以及反映小气道功能的部分平均通过时间。求出了与年龄相关的直线回归方程,分析了平均通过时间、反映小气道功能的部分平均通过时间的影响因素和临床意义。初步认为平均通过时间和反映小气道功能的部分平均通过时间是检测小气过阻塞敏感的肺功能指标。

The correlation between five parameters in small airway function tests (CV/VC%, CC/TLC%, △N_2/L, and ) in 93 healthy adults and 32 patients with limited pulmonary disease was reported. The correlation between and was closer in both the healthy adults group and the patients group. No significant correlation was found between CV/VC% and △N_2/L in healthy male group and patients group, but slight correlation was found between CV/VC% and △N_2/L in healthy female group The machanism of those phenomena was tentatively...

The correlation between five parameters in small airway function tests (CV/VC%, CC/TLC%, △N_2/L, and ) in 93 healthy adults and 32 patients with limited pulmonary disease was reported. The correlation between and was closer in both the healthy adults group and the patients group. No significant correlation was found between CV/VC% and △N_2/L in healthy male group and patients group, but slight correlation was found between CV/VC% and △N_2/L in healthy female group The machanism of those phenomena was tentatively discussed. The authors suggest that in the assessment of small airway function it is better to use several parameters together.

本文报告了93名健康成人和32例肺部局限性病变患者五项小气道功能指标(CV/VC%,CC/TLC%、AN_2/L、_(50)和_(25))之间的相关性,发现健康成人和肺部疾病患者的守_(60)与_(26)之间的相关性最好,而健康男性和肺部疾病组的CV/VC%与△N_2/L无显著相关,健康女性组CV/VC%与△N_2/L仅轻度相关,对于上述现象的原因提出初步推测,并认为在判断小气道功能时应将各项指标综合考虑。

 
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