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肝细胞肝癌     
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  hepatocellular carcinoma
     Expressions of p21~(WAF1/CIP1) and p27~(KIP1) in Hepatocellular Carcinoma
     肝细胞肝癌中p21~(WAF1/CIP1)和p27~(KIP1)蛋白表达的研究
短句来源
     In 46 patients with hepatocellular carcinoma,1-and 2-year recurrence rate after operation were 13.04%(6/46) and 23.91%(11/46),1-and 2-year mortality were 6.52%(3/46) and 13.04%(11/46).
     46例肝细胞肝癌中,术后1、2年复发率分别为13.04%(6/46)、23.91%(11/46); 病死率分别为6.52%(3/46)、13.04%(6/46),生存率分别为93.47%(43/46)及86.95%(40/46)。
短句来源
     The Expression of Survivin, NF-κB and nm-23h1 Protein in Hepatocellular Carcinoma
     Survivin、NF-κB和nm-23h1在肝细胞肝癌中的表达及意义
短句来源
     Expression and Significance of COX-2, Ki-67, survivin in Hepatocellular Carcinoma
     COX-2,Ki-67,survivin在肝细胞肝癌中的表达及其意义
短句来源
     The relationships between expression of P21~(WAF1) and p53 and between P21~(WAF1) and PCNA in tissues of hepatocellular carcinoma and liver cirrhosis
     肝细胞肝癌和肝硬变组织中P21~(WAF1)与P53,PCNA表达之间的关系
短句来源
更多       
  hepatocellular carcino ma
     Expressions of p21~(WAF1/CIP1) and p27~(KIP1) in Hepatocellular Carcinoma
     肝细胞肝癌中p21~(WAF1/CIP1)和p27~(KIP1)蛋白表达的研究
短句来源
     In 46 patients with hepatocellular carcinoma,1-and 2-year recurrence rate after operation were 13.04%(6/46) and 23.91%(11/46),1-and 2-year mortality were 6.52%(3/46) and 13.04%(11/46).
     46例肝细胞肝癌中,术后1、2年复发率分别为13.04%(6/46)、23.91%(11/46); 病死率分别为6.52%(3/46)、13.04%(6/46),生存率分别为93.47%(43/46)及86.95%(40/46)。
短句来源
     The Expression of Survivin, NF-κB and nm-23h1 Protein in Hepatocellular Carcinoma
     Survivin、NF-κB和nm-23h1在肝细胞肝癌中的表达及意义
短句来源
     Expression and Significance of COX-2, Ki-67, survivin in Hepatocellular Carcinoma
     COX-2,Ki-67,survivin在肝细胞肝癌中的表达及其意义
短句来源
     The relationships between expression of P21~(WAF1) and p53 and between P21~(WAF1) and PCNA in tissues of hepatocellular carcinoma and liver cirrhosis
     肝细胞肝癌和肝硬变组织中P21~(WAF1)与P53,PCNA表达之间的关系
短句来源
更多       
  “肝细胞肝癌”译为未确定词的双语例句
     Expression and Significance of E2f-3, Bcl-2 in Hepatocellular Carcinomar
     肝细胞肝癌中E2f-3、Bcl-2的表达及意义
短句来源
     Methods The dynamic changes of CD3~+,CD4~+,CD8~+,CD8~+CD28~+,CD16~+CD56~+ subsets were detected in 163 patients with HCC by flowcytometry,and MTT colometric assay was applied to detect the activity of IL-2 perioperatively.
     方法163例肝细胞肝癌患者手术前及手术后5、101、5 d外周血CD3+、CD4+、CD8+、CD8+CD28+、CD16+CD56+的变化用流式细胞仪检测,白细胞介素2(IL-2)活性用MTT比色法测定。
短句来源
     Expression of C,E,NS3 and NS4 region antigens of Hepatitis C virus
     肝细胞肝癌中丙型肝炎病毒C区、E区、NS3区、NS4区抗原的表达
短句来源
     Results: The positive rate of expression of SSTR 1 mRNA was 18.7%(9/48) in the tissues of hepatic carcinoma and 31.3%(16/48) in the adjacent tissues of cancers.
     结果48例肝细胞肝癌患者的癌组织和癌旁组织中SSTR1mRNA表达的阳性率分别为18.7%(9/48)和31.3%(16/48);
短句来源
     Expression of p21~(WAF1/CIP1)and Rb Proteins in Hepatocelluar Carcinoma by Tissue Chip
     利用组织芯片研究p21~(WAF1/CIP1)和Rb基因在肝细胞肝癌中的表达
短句来源
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  hepatocellular carcinoma
Cancer-related genes harbored in the loss regions containing a high frequency of hepatocellular carcinoma (HCC) were selected.
      
We recognized and honoured the important contributions of these Chinese pioneers in portal hypertension, recurrent pyogenic cholangitis, hepatocellular carcinoma and liver transplantation.
      
Surgical treatment of hepatocellular carcinoma with cirrhotic esophageal varices and hypersplenism: a 184 case report
      
In treating hepatocellular carcinoma (HCC) patients with advanced cirrhosis, one of the most difficult problems is concomitant esophageal varices and hypersplenism.
      
Clinical outcomes of ATP-tumor chemosensitivity assay directed chemotherapy in hepatocellular carcinoma
      
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  the hepatocellular cancer
Expression of the NT/N gene may provide insight into the particular cell lineage that gives rise to the hepatocellular cancer.
      


In 1974, primary hepatomas wereinduced in Wistar rats by treatmentwith Diethylnitrosamine (DENA) andfrom them an AFP(+) transplantablehepatoma designated as BERH-2 wasestablished in the same rat strain. Theprimary tumor was derived from pa-renchymal liver cells and up to nowthe transplantable tumor line has givena steady growth rate and has beenserially passed through more than 70generations. By means of immunodif-fusion and rocket immunoelectrophoresis,both the sera from rats bearing theprimary hepatoma and...

In 1974, primary hepatomas wereinduced in Wistar rats by treatmentwith Diethylnitrosamine (DENA) andfrom them an AFP(+) transplantablehepatoma designated as BERH-2 wasestablished in the same rat strain. Theprimary tumor was derived from pa-renchymal liver cells and up to nowthe transplantable tumor line has givena steady growth rate and has beenserially passed through more than 70generations. By means of immunodif-fusion and rocket immunoelectrophoresis,both the sera from rats bearing theprimary hepatoma and those during suc-cessive transplant generations were shownto contain AFP. Moreover, there existeda positive correlation between the growthrate of this hepatoma and the amountof AFP found in host serum. Based onultrastructure observations, two types oftumor cells having matrices with diffe-rent electron densities were found.

1974年在Wistar品系大鼠用DENA诱发得原发性肝癌,移植于同品系幼鼠建立了一株AFP为阳性的大鼠移植性肝癌,命名为BERH-2。病理鉴定为肝细胞肝癌,至今已三年多,传至第70余代,目前生长稳定。利用免疫学方法测定这株BERH-2肝癌的原发灶及建株过程中各代宿主的血清,AFP恒呈阳性。超微结构表明存在着基质电子密度不同的两类细胞。BERH-2肝癌的生长与宿主血清中AFP含量的增加呈平行的正相关。

Hepatocellular carcinoma.was induced in all the male albino rats with an average body weight of 145±25.8gm by feeding diethylnitrosanaine(DEN)96.1±1.61 to 185 ±0 mg,during 90±1.73 to 195±0 days. Many hyperplastic and carcinogenic nodules instead of normal lobular structure were observed in the affected liver.The maximum diameter of the carcingenic nodule is 3.5 cm. The tumour tissues can be divided into three types:A,B,and M.Type A is com- posed of large-sized acidophilic hepatomic cells which are arranged in...

Hepatocellular carcinoma.was induced in all the male albino rats with an average body weight of 145±25.8gm by feeding diethylnitrosanaine(DEN)96.1±1.61 to 185 ±0 mg,during 90±1.73 to 195±0 days. Many hyperplastic and carcinogenic nodules instead of normal lobular structure were observed in the affected liver.The maximum diameter of the carcingenic nodule is 3.5 cm. The tumour tissues can be divided into three types:A,B,and M.Type A is com- posed of large-sized acidophilic hepatomic cells which are arranged in the form of hepatocarcinoma muraliosum duplex or triplex.Type B is composed of small-sized baso- philic hepatomic cells which are arranged in the form of hepatocarcinoma muraliosum multiplex.Type M is composed of mixed acidophilic and basophilic hepatomic cells. When 98.1±1.61 mg of DEN was fed in a duration of 90±1.73 days only Type A hepatomic tissue was induced,while 123±2.35 mg in a duration of 123±3.81 days was fed all the three types of hepatomic tissue were observed in liver and also meta- stases of the hepatonaic tissue. Large-sized hepatomic cells with multiple nuclei were found in all the three types of hepatomic tissue.The metastatic hepatomic tissue belongs to Type A or B. The hepatomic cells are PAS-negative in contrast with the normal strongly PAS- positive hepatic cells;in hyperplasnc nodules;and more DNA and RNA inhepatomic nodules thanin normal cells.The basophilic substance in the hepatomic cells appears in the form of concentric lamellae,reticulum,rough or dust-like particles.The precarcinogenic or carcinogenic area in liver is characterized by the decrease of glycogen,increase of baso- philia and nuclear DNA,and the change of hepatocellular muraliosum from simplex to multiplex. From the above observation the author advances a hypothesis that the hepatomic tissue arises from the burst of cell division of the hepatic cells in the hyperplastic nodules.

本实验采用口喂二乙基亚硝胺(DEN)诱发大白鼠肝癌,在肝癌模型建立过程中观察其癌变过程和肝癌组织的结构特点。1.口喂 DEN 诱发肝癌,在总剂量达96.1±1.61毫克至185±0毫克;致癌日期90±1.73天至195±0天时可使体重146±25.8克雄性大白鼠全部获得肝细胞肝癌。2.口喂 DEN 总剂量达96.1±1.61毫克,致癌日期90±1.73天可获得 A 型(嗜酸性)肝癌组织;总剂量达123±2.35毫克,致癌日数123±3.81天起可获得 B 型(嗜硷性)、A 型和 M 型(混合型)三型肝癌组织与肝癌的转移材料。3.采用 PAS 反应法,在显微镜下很易鉴别增生结节和肝癌结节,因前者呈强阳性而后者呈阴性。在某些增生结节与肝癌结节中均存在一些 PAS 反应呈弱阳性的肝细胞(或肝癌细胞)。4.肝细胞癌变过程中的特点是糖原下降最后消失,嗜硷性物质(核糖核酸)和去氧核糖核酸增加。

This study investigates the ultrastructural changes of hepatocytes during hepatocarcinogenesis in Sprague-Dawley rats fed with diethylnitrosamine(DEN). The liver cells underwent a series of ultrastructural changes before they became light microscopically demonstrable malignant cells. Occurrence of these transitional changes in oval cells strongly indicates that the oval cells may be the precursor of hepatoma.

报道二乙基亚硝胺诱发Sprague-Dawley(SD)大鼠肝癌发生过程中肝细胞超微结构的动态改变。发现早在肉眼和光镜发现肿瘤之前,肝细胞就发生了一系列超微结构改变,且观察到卵圆细胞向高度嗜硷性肝细胞、肝细胞肝癌转化的连续变化谱。

 
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