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一次环
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     Objective To evaluate the efficiency of double encircling in the treatment of recurrent retinal detachment failure to single encircling procedure Method We studied retrospectively 104 cases undergone double encircling or double encircling combined with vitrectomy from 1996 1 to 1999 3 Results The retinal reattachment,visual acuity and complication following surgery were assessed after mean follow-up of 6-18 months The success rate for the surgery was 91 35%.
     方法 回顾分析自 1996年 1月至 1999年 3月进行双环扎手术或双环扎结合玻璃体手术的 10 4例 10 4眼。 其中 6 8眼有一次环扎手术史 ,16眼有一次环扎 +玻璃体切除手术史 ,2 0眼有两次以上包括环扎的视网膜脱离手术史。
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     DQrC
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120 pieces of silk suture (1#&4# ) were sterilized with formaldehyde at differrent time period,Group II and III each had 20 pieces and was disinfected with ethylene oxide or high pressure respectively.The tension of each silk suture was measured with tensomether. The result showed that there was no significant difference compared with the control groups (P>0. 05 ). This suggests that silk suture maintains the same tension in the experiments: after repeated sterilization with formaldehyde, with ethylene oxide,...

120 pieces of silk suture (1#&4# ) were sterilized with formaldehyde at differrent time period,Group II and III each had 20 pieces and was disinfected with ethylene oxide or high pressure respectively.The tension of each silk suture was measured with tensomether. The result showed that there was no significant difference compared with the control groups (P>0. 05 ). This suggests that silk suture maintains the same tension in the experiments: after repeated sterilization with formaldehyde, with ethylene oxide, or with highpressure sterilization once.

将1#、4#丝线共80条分4组(消毒时间分别为1日、1周、2周和3周),用甲醛熏蒸消毒。另两组1#、4#丝线共40条分别用环氧乙烷和高压蒸气消毒。消毒后测试其拉力强度,结果与对照组相比,差异无显著性(P>0.05)。结论:丝线经甲醛反复熏蒸或经一次环氧乙烷消毒、高压蒸气消毒后,拉力强度不受影响。

Aim To observe the relation between the blood cyselosporine concentration. Methods The therapeutic drug monitoring data of cyclosporine in 97 kidney - transplanted recipi ents in 8 weeks, from May 1995 to October 1996, were analysed retrospectively. The re cipients were sorted in three groups, the normal group, the acute rejection group and the acute toxicity group. Blood cyclosporine concentration was measured by FPIA with mon oclonal antibody reagent. Results In normal group, 62 recipients had good kidney...

Aim To observe the relation between the blood cyselosporine concentration. Methods The therapeutic drug monitoring data of cyclosporine in 97 kidney - transplanted recipi ents in 8 weeks, from May 1995 to October 1996, were analysed retrospectively. The re cipients were sorted in three groups, the normal group, the acute rejection group and the acute toxicity group. Blood cyclosporine concentration was measured by FPIA with mon oclonal antibody reagent. Results In normal group, 62 recipients had good kidney function, with average daily dose of cyclosporine 5.2± 1. 9 mg/ kg · d, the blood concen- tration of cyclosporine was 309. 85 ± 131. 69 μg/L ; In acute rejection group, the average daily dose in 26 recipients was 4.8±1.6mg/kg·d, the blood concentration of cyclosporine pend- ing rejection episode was 165. 80± 123. 13 μg/ L; In acute toxicity group, the average daily dose in 9 recipients was 6. 2 ±1. 0 mg/ kg· d, the cyclosporine blood concentration pending toxicity episode was 556. 51 ± 102. 50 μg/ L. There was no sigificant difference among the three groups on the average daily dose of cyclosporine (P> 0. 05). However the blood concentration of cyclosporine in three groups varied greatly and there was significant dif ference among them(P< 0.05, even P< 0.01 between acute rejection group vs toxicity group) . Conclusion In therapeutic drug monotoring of cyclosporine measurement of blood drug concentration is extremely important . More acute rejection episodes occur with low blood concentration of cyclosporine, while more toxicity episodes happen with high blood concentration.

目的 观察环孢素血药浓度与肾移植效果间关系。方法 对97例接受同种异体肾脏移植术受者术后8周内206例次环孢素血药浓度监测结果进行回顾性分析,按照受者术后的临床表现、生化指标将其分为术后正常组、急性排斥组、急性毒性组,采用荧光偏振免疫测定法,以单克隆抗体试剂测定环孢素血药浓度。结果 术后正常组62例移植肾功能良好,环孢素的给药剂量为52±1.9 mg/kg·d,171例次环孢素血药浓度的平均值为309.85±131.69μg/L;术后急性排斥组 26例,距发生排斥反应最近一次的环孢素血药浓度平均为165.80±123.13μg/L,环孢素的给药剂量为 4.8±1.6mg/kg·d;术后急性毒性组9例,距发生毒性反应最近一次的环孢素血药浓度平均为556.51±102.50μg/L,环孢素的给药剂量为6.2±1.0mg/kg·d。三组之间环孢素的给药剂量无显著性差异(P>0.05),但环孢素血药浓度却相差很大,两两之间有显著性差异(正常组与排斥组 P< 0.05;正常组与毒性组P< 0.05;排斥组与毒性组P< 0.01)。结论 环孢素浓度较低时,出现排斥反应的可能性较大;而环孢素浓度较高时,发生毒性反应的机会较...

目的 观察环孢素血药浓度与肾移植效果间关系。方法 对97例接受同种异体肾脏移植术受者术后8周内206例次环孢素血药浓度监测结果进行回顾性分析,按照受者术后的临床表现、生化指标将其分为术后正常组、急性排斥组、急性毒性组,采用荧光偏振免疫测定法,以单克隆抗体试剂测定环孢素血药浓度。结果 术后正常组62例移植肾功能良好,环孢素的给药剂量为52±1.9 mg/kg·d,171例次环孢素血药浓度的平均值为309.85±131.69μg/L;术后急性排斥组 26例,距发生排斥反应最近一次的环孢素血药浓度平均为165.80±123.13μg/L,环孢素的给药剂量为 4.8±1.6mg/kg·d;术后急性毒性组9例,距发生毒性反应最近一次的环孢素血药浓度平均为556.51±102.50μg/L,环孢素的给药剂量为6.2±1.0mg/kg·d。三组之间环孢素的给药剂量无显著性差异(P>0.05),但环孢素血药浓度却相差很大,两两之间有显著性差异(正常组与排斥组 P< 0.05;正常组与毒性组P< 0.05;排斥组与毒性组P< 0.01)。结论 环孢素浓度较低时,出现排斥反应的可能性较大;而环孢素浓度较高时,发生毒性反应的机会较多。

Objective To evaluate the efficiency of double encircling in the treatment of recurrent retinal detachment failure to single encircling procedure Method We studied retrospectively 104 cases undergone double encircling or double encircling combined with vitrectomy from 1996 1 to 1999 3 Results The retinal reattachment,visual acuity and complication following surgery were assessed after mean follow-up of 6-18 months The success rate for the surgery was 91 35%.9 of 11 cases with anterior proliferative...

Objective To evaluate the efficiency of double encircling in the treatment of recurrent retinal detachment failure to single encircling procedure Method We studied retrospectively 104 cases undergone double encircling or double encircling combined with vitrectomy from 1996 1 to 1999 3 Results The retinal reattachment,visual acuity and complication following surgery were assessed after mean follow-up of 6-18 months The success rate for the surgery was 91 35%.9 of 11 cases with anterior proliferative vitreoretinopathy were reattached for the retina(success rate 81 82%) Moreover, 13 out of 16 cases with retinal impaction and fixed fold showed retinal reattachment(success rate 81 25%) Besides,retinal reattachment occurred in 73 of 77 cases with new retinal tears (success rate 94 81%) Conclusions The double encircling is a simple and efficient method to treat recurrent retinal detachment failure to single encircling procedure.

目的 探讨双环扎手术在有过手术史的复发性视网膜脱离的临床效果。方法 回顾分析自 1996年 1月至 1999年 3月进行双环扎手术或双环扎结合玻璃体手术的 10 4例 10 4眼。其中 6 8眼有一次环扎手术史 ,16眼有一次环扎 +玻璃体切除手术史 ,2 0眼有两次以上包括环扎的视网膜脱离手术史。结果 随访 6至 18个月 ,手术成功率 91.35 % ;其中前部玻璃体视网膜病变的 11眼中 9眼视网膜复位 ,成功率为 81.82 % ;视网膜嵌顿和固定皱襞的 16眼中 13眼视网膜复位 ,成功率 81.2 5 % ;视网膜新裂孔的 77眼中 73眼视网膜复位 ,成功率 94.81%。结论 对于部分有过手术史的复发性视网膜脱离 ,双环扎手术是一种简便有效的手术方法。

 
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