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渗透量
相关语句
  permeation quantity
    The permeability coefficient and cumulative permeation quantity(8 h) of DET sustained release cream were 0.0157 mg·cm-2·h-1 and 0.13 mg·cm-2,respectively.
    cm-. 2h-1,8 h累积渗透量为0.13 mg.
短句来源
    The penetration of ketoprofen in the cataplasm through the BLAB/c mouse skin followed zero-order dynamics in 24 h. Its release equation in vitro was Q= 10. 196 t-7. 954 7 (r=0. 998 8). The cumulative permeation quantity in 24 h was 244. 70μg/cm2 through BLAB/c mouse skin in vitro.
    巴布剂中的酮洛芬24 h内以零级动力学经皮渗透,体外经皮释药方程为Q=10.196 t-7.954 7(r=0.998 8),24 h累积渗透量为244.70μg/cm2。
短句来源
    The permeation enhancing multiple of 3% Azone group is the highest which is 8.1.CONCLUSION With the cumulative permeation quantity of ferulic acid as the index, 3% azone is more suitable to act as a permeation enhamer of CHP.
    结论 以阿魏酸累积渗透量为指标 ,选择 3%氮酮作为复方骨质增生贴剂的渗透促进剂更为适宜
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  “渗透量”译为未确定词的双语例句
    The permeation rate was 77.68μg/h·cm2.This film showed a remarkable therapeutic effect on asthma.
    0~12h累积渗透量为40.4%,渗透速率77.68μg/cm2·h,本品有显著平喘作用,其作用优于氨茶碱溶液剂。
短句来源
    A second order derivative spectrophotometric method was developed for the permeative determination of ketoprofen in vitro .
    为进一步探讨酮洛芬透皮给药的可行性,用二阶导数光谱法测定酮洛芬体外经皮渗透量
短句来源
    RESULTS: The penetration equation of ketoprofen film was Q=0.438 5 t-0.103 0 (r=0.999 8). The cumulative release level in 8 h was 3.507 mg·cm -2 through rat skin in vitro.
    结果:KTP涂膜剂体外透皮释药方程为:Q=0.4385t-0.1030(r=0.9998),8h累积渗透量为3.507mg·cm-2;
短句来源
    The tritium water penetration amount through skin was applied as an index of evaluating skin barrier function.
    方法对3天龄SD大鼠的活体皮肤进行氯仿涂搽、接触10和20min的处理,采用静式渗透模型,以氚水经皮渗透量作为皮肤屏障功能的评价指标。
短句来源
    The results showed that 1%~5% menthnol and 1%~5% azone markedly enhanced the cumulation penetration (Q) and the penetration rate ( k ) of 2% ketoprofen Gel ( P <0 01);
    比较其结果,1% ~5% 薄荷脑、1% ~5% 氮酮对2% 酮洛芬凝胶的累积渗透量Q 及渗透速率k 均显著地提高(P< 0.01);
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For the purpose of comparison, percutaneous absorption of three radioactive pesticides (3H-Paraoxon, 14C-Chlordimeform and 14C-Permethrin) was studied in vivo in rabbits and guinea pigs, and pairing with in vitro test on pieces of skin flap which had been stripped from adjacent area of the same animal.Results showed that the amount of permeation is time dependent. The amount of permeation of in vitro test was on the whole higher than that of in vivo. The data between the two sets of test were closely correlated...

For the purpose of comparison, percutaneous absorption of three radioactive pesticides (3H-Paraoxon, 14C-Chlordimeform and 14C-Permethrin) was studied in vivo in rabbits and guinea pigs, and pairing with in vitro test on pieces of skin flap which had been stripped from adjacent area of the same animal.Results showed that the amount of permeation is time dependent. The amount of permeation of in vitro test was on the whole higher than that of in vivo. The data between the two sets of test were closely correlated in cases of Paraoxon in both rabbits and guinea pigs and of Chlordimeform in rabbits. Data of radioassay from blood samples proved to be not a good indicator of absorption on account of variations in their permeation rate and uneven re-distribution in the body.In view of the relative rapidity, simplicity and sensitivity of in vitro assay, especially in the case with guinea pig skin, which has a comparable permeability to human skin, it is therefore suggested that in vitro test with guinea pig skin could be used in place of in vivo test for percutaneous absorption of chemicals.

本文用同体动物皮肤配对,比较了~3H-对氧磷、~(14)C-杀虫脒、~(14)C-拟除虫菊酯经离体与活体皮肤的吸收。结果表明离体实验的时间-渗透量相关程度,一般均高于活体实验,同时见到对氧磷在兔和豚鼠皮以及杀虫脒在兔皮上存在离体与活体皮肤渗透量的高度相关。由于活体实验中化学物经皮肤渗透入血液的再分配等原因,致使用血液中的放射性量不能完全代表经皮肤的渗透量。本文实验结果表明采用离体皮肤进行化学物经皮肤吸收的研究,可以估计活体皮肤吸收的状况,且具有快速、灵敏、节约材料等优点。建议今后可采用渗透速度接近人皮的豚鼠皮,进行化学物经皮吸收的离体实验来替代活体实验。

Heparin 50 mg/kg injected intravenously to rabbits can reduce the permeability of aortic endothelia,which is enhanced by intravenous noradrenaline, It can reduce the permeability of the Evan's blue-Albumine compounds,and reduce both the quantity and depth of the compound.Higher effects can be obtained with increasing dosages both high and lower active heparins,but it has no relation with the anticoagulation action.

给家兔静脉注射不同效价的肝素,利用显微荧光扫描术研究内皮细胞的通透性,见由去甲肾上腺素所致的主动脉内皮细胞通透性增加有抑制作用,可降低主动脉内皮细胞对伊文思蓝-白蛋白复合物的通透性,对单位面积内伊文思蓝的渗透量和主动脉壁伊文思蓝的渗透深度,均有非常显著的影响。

A special kind of silicone matrix containing estradiol (E_2) formaking of "microreservoir partition-controlled transdermal drug delivery system"is introduced. With. Franz diffusion cell and Valia-Chien diffusion cell, the resultsshowed: (1) E_2 release from the TDS fitted the Higuchi equation; (2) E_2 skinpermeation rate was nearly zero-order. The E_2 transdermal rate and amountcould be adjusted by changing the component proportions and/or adding variousenhancers of different proportions in matrix.

报道了一种采用国产硅橡胶为骨架材料的“微小贮库分配控制型”药物透皮释放系统(TDS)。Franz渗透池TDS体外释放试验和Valia-Chien渗透池皮肤渗透试验表明;①雌二醇从TDS的体外释放规律符合Higuchi方程式;②雌二醇TDS的皮肤渗透速率接近零级速率。改变TDS配方中不同组分的比例或加入不同类型、不同比例的透皮吸收促进剂可以调节雌二醇的皮肤渗透速率与渗透量

 
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