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慢性乙型病毒性肝炎chb
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  “慢性乙型病毒性肝炎(chb)”译为未确定词的双语例句
     Objective To observe effect of psychic intervention on recombinant interferon-α2b(rIFN-α2b) therapy in patients with chronic hepatitis B(CHB).
     目的分析心理干预对慢性乙型病毒性肝炎(CHB)患者重组干扰素-α2b(rIFN-α2b)疗效的影响。
短句来源
     Objective To evaluate the clinical significance of determining the serum transforming growth factor beta-1(TGF-β1) in the patients with chronic viral hepatitis B(CHB).
     目的 评价慢性乙型病毒性肝炎 (CHB)患者血清转化生长因子 β1(TGF β1)测定的临床意义。
短句来源
     Objective To study the relationship between the expression of CD80/CD28 in peripheral blood T lymphocytes and virus load in patients with chronic hepatitis B (CHB).
     目的研究慢性乙型病毒性肝炎(CHB)患者外周血T淋巴细胞CD80/CD28表达率与血清HBV-DNA之间的相关关系。
短句来源
     ObjectiveTo observe the relation between serum soluble intercellular adhesion molecule-1(sICAM-1)and liver fibrosis in chronic hepatitis B(CHB), chronic severe hepatitis B(CSH) and liver cirrhosis(LC).
     【目的】探讨可溶性细胞间粘附分子 1(sICAM 1)在慢性乙型病毒性肝炎 (CHB)、重型乙型病毒性肝炎 (CSH)及肝硬化 (LC)患者血清中的水平及其与肝纤维化的关系。
短句来源
     Methods Pre-PHA-cultivated and post-PHA-cultivated expression levels of CCR5 and CD30 of PMBC of 20 hepatitis B patients and 20 normal subjects were assayed by flow cytometry.
     方法对 2 0例正常人群 (NC)及 2 0例慢性乙型病毒性肝炎 (CHB)患者外周血单核细胞 (PMBC)经植物血凝素 (PHA)培养前后CCR5、CD30的表达水平进行了检测。
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  相似匹配句对
     New Management of Chronic Viral Hepatitis B
     慢性病毒性肝炎治疗新方法
短句来源
     OBJECTIVE:To evaluate the therapeutic effects of interferon combined with kushenin in the treatment of Chronic Hepatitis B(CHB).
     目的 :评价干扰素联合苦参素治疗慢性病毒性肝炎 (CHB)的疗效。
短句来源
     Scientific Treatment and Prevention for Chronic Viral Hepatitis B
     慢性病毒性肝炎的科学治疗与预防
短句来源
     Analysis on the Investigation About the Prevalence Rate of Chronic HBV Infection
     慢性病毒性肝炎患病率调查方法的探讨
短句来源
     Clinical meaning of serum ferritin,iron in chronic hepatitic B
     慢性病毒性肝炎血清铁及铁蛋白检测
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Objective\ To study the relationship between the changes of Interleukin and Receptor in serum of patients with chronic hepatitis B (CHB) before and after Interferon α (IFN α) treatment and expression of HBV marker. Methods: Enzyme liked immunosorbent assay (ELISA) were performed in 25 patients with CHB to determine levels of IL 6\, IL 2\,TNF α\, IL 8\, sIL 2R in serum. Results: Our date showed that the IL 6 level in response group after IFN α treatment was significantly lower than that befor (P<0.05)....

Objective\ To study the relationship between the changes of Interleukin and Receptor in serum of patients with chronic hepatitis B (CHB) before and after Interferon α (IFN α) treatment and expression of HBV marker. Methods: Enzyme liked immunosorbent assay (ELISA) were performed in 25 patients with CHB to determine levels of IL 6\, IL 2\,TNF α\, IL 8\, sIL 2R in serum. Results: Our date showed that the IL 6 level in response group after IFN α treatment was significantly lower than that befor (P<0.05). The level of IL 2 in unresponse group after IFN α treatment was significantly decreased, but the level in response group was significantly increased (P<0.01), but the serum sIL 2R level in patients with response was significantly decreased (P<0.01). The TNF α level in both response and unresponse group after IFN α treatment was significantly decreased (P<0.01), but the serum IL 8 level was increased. Conclusion\ The results suggest that HBV replication in patients with CHB could be also affected by immunoregulation of IFN α for IL 6\,IL 2\,sIL 2R, but HBV replication could be not affected by TNF α and IL 8 levels in serum.

观察慢性乙型病毒性肝炎 (CHB)患者 ( 2 5例 )经α 干扰素 (IFN α)抗病毒治疗前后血清中细胞因子和受体水平的变化与乙肝病毒消长之间的关系。收集治疗前后血清标本ELISA法同步检测 ,根据治疗后乙肝病毒复制指标 (HBV DNA)阴转分应答组 ( 10例 )与无应答组 ( 15例 )进行统计学分析。治疗后两组血清中IL 6水平下降 ,尤其应答组下降明显 ;治疗后应答组IL 2水平明显升高 (P <0 .0 1) ,sIL 2R水平则明显下降 ;但治疗后两组TNF α均较治疗前下降 ,相反IL 8水平升高接近正常人水平 ;CHB患者体内存在免疫功能的失调 ,通过IFN α免疫调节 (IL 6、IL 2、sIL 2R)对病毒复制影响具有重要作用。但TNF α和IL 8表达与病毒复制消长无相关关系

Objective:To evaluate the curative effect of using Lamivudine and Interferon for chronic hepatitis B.Methods:Lamivudine and Interferon separated or combined therapeutics application were took place in chronic hepatitis B patients and the dynamic variety about symptoms,ALT,viral marker before and after therapy were observed.Results:There was 81.6%(62/76)HBV DNA,38.2%(26/68)HBeAg negative rate and 25%(16/68) anti HBe positive rate in combined application group at the end of therapy.The Lamivudine or Interferon...

Objective:To evaluate the curative effect of using Lamivudine and Interferon for chronic hepatitis B.Methods:Lamivudine and Interferon separated or combined therapeutics application were took place in chronic hepatitis B patients and the dynamic variety about symptoms,ALT,viral marker before and after therapy were observed.Results:There was 81.6%(62/76)HBV DNA,38.2%(26/68)HBeAg negative rate and 25%(16/68) anti HBe positive rate in combined application group at the end of therapy.The Lamivudine or Interferon application alone showed 70.8%(17/24),33.3%(10/30)HBV DNA;10%(2/20),40%(12/30)HBeAg negative rate and 5%(1/20),10%(3/30)anti HBe positive rate respectively.All the sera ALT became normal after 12 weeks later.The symptoms of hepatitis were improved.The application of interferon showed more side effect,but commonly did not affect the therapeutics.Conclusion:There is a better curative effect in combined application group in general.

目的 :观察拉米夫定 (3- TC)与干扰素 (IFN)联合与单用治疗慢性乙型病毒性肝炎 (CHB)的疗效。方法 :以 2种药物分别单用或联合应用 ,治疗 130例 CHB患者 ,观察治疗前后各自临床症状、AL T、病毒标志物水平的变化。结果 :治疗结束时联合用药组 HBV- DNA阴转率为 81.6 % (6 2 / 76 ) ,HBe Ag阴转率为 38.2 % (2 6 / 6 8) ,抗 - HBe阳转率为 2 5 % (17/ 6 8) ;单用 3TC组 HBV- DNA阴转率为 70 .8% (17/ 2 4) ,HBe Ag阴转率为 10 % (2 / 10 ) ,抗 - HBe阳转率为 5 % (1/ 2 0 ) ;单用 IFN组 HBV- DNA阴转率为 33.3% (10 / 30 ) ,HBe Ag阴转率为 40 % (12 / 30 ) ,抗 - HBe阳转率为 10 % (3/ 30 )。各组患者 AL T水平于 12周以后均正常。肝炎临床症状改善 ,应用 IFN者副作用稍多 ,但多数患者可以耐受治疗。结论 :联合用药组综合疗效优于单独用药组

Objective To study that if CCR5 and CD30 could be respectively used as the cell surface markers of 1,2 type of T helper and cytotoxic cell (Th1/Tc1,Th2/Tc2)and the roles of Th/Tc subtype cells in the immunological pathogenesis of viral hepatitis.Methods Pre-PHA-cultivated and post-PHA-cultivated expression levels of CCR5 and CD30 of PMBC of 20 hepatitis B patients and 20 normal subjects were assayed by flow cytometry.Results Before cultivation,there...

Objective To study that if CCR5 and CD30 could be respectively used as the cell surface markers of 1,2 type of T helper and cytotoxic cell (Th1/Tc1,Th2/Tc2)and the roles of Th/Tc subtype cells in the immunological pathogenesis of viral hepatitis.Methods Pre-PHA-cultivated and post-PHA-cultivated expression levels of CCR5 and CD30 of PMBC of 20 hepatitis B patients and 20 normal subjects were assayed by flow cytometry.Results Before cultivation,there was no discrepancy between NC and CHB,but the CCR5 levels of the two groups were higher than that of CD30;After cultivation,CCR5 of CHB was higher than that of NC,but CD30 was lower than NC;CD30,CDR5 and CCR5/CD30 levels between pre-cultivation and post-cultivation had obvious discrepancy.Conclusion ①CCR5 and CD30 could be used as the specific markers of Th,Tc subtypes.②Abnormal or disorder expression levels between CCR5 and CD30 might have some relationship with the pathogenesis of viral hepatitis.

目的 为研究细胞趋化因子受体 5 (CCR5 )及细胞分化抗原 30 (CD30 )作为 1类辅助性T细胞 /细胞毒性T细胞 (Th1/Tc1)、2类辅助性T细胞 /细胞毒性T细胞 (Th2 /Tc2 )表面标志的可行性及辅助性T细胞 (Th) /细胞毒性T细胞亚群 (Tc)在病毒性肝炎免疫发病机制中的作用。方法对 2 0例正常人群 (NC)及 2 0例慢性乙型病毒性肝炎 (CHB)患者外周血单核细胞 (PMBC)经植物血凝素 (PHA)培养前后CCR5、CD30的表达水平进行了检测。结果 ①培养前 ,NC与CHB患者PM BC的CCR5及CD30的表达无明显的差别 (P >0 0 5 ) ,但两组CCR5的表达均高于CD30 (P <0 0 5 )。②培养后 ,CHB患者CCR5高于NC(P >0 0 5 ) ,而CD30则低于NC(P <0 0 5 )。③培养后 ,NC的CCR5表达较培养前明显的减少 (P <0 0 5 ) ,而NC及CHB患者的CD30的表达较培养前均明显的增加 (P <0 0 5 ) ;培养后 ,CHB患者CCR5的减少量低于NC ,而CD30的增加量少于NC(P <0 ...

目的 为研究细胞趋化因子受体 5 (CCR5 )及细胞分化抗原 30 (CD30 )作为 1类辅助性T细胞 /细胞毒性T细胞 (Th1/Tc1)、2类辅助性T细胞 /细胞毒性T细胞 (Th2 /Tc2 )表面标志的可行性及辅助性T细胞 (Th) /细胞毒性T细胞亚群 (Tc)在病毒性肝炎免疫发病机制中的作用。方法对 2 0例正常人群 (NC)及 2 0例慢性乙型病毒性肝炎 (CHB)患者外周血单核细胞 (PMBC)经植物血凝素 (PHA)培养前后CCR5、CD30的表达水平进行了检测。结果 ①培养前 ,NC与CHB患者PM BC的CCR5及CD30的表达无明显的差别 (P >0 0 5 ) ,但两组CCR5的表达均高于CD30 (P <0 0 5 )。②培养后 ,CHB患者CCR5高于NC(P >0 0 5 ) ,而CD30则低于NC(P <0 0 5 )。③培养后 ,NC的CCR5表达较培养前明显的减少 (P <0 0 5 ) ,而NC及CHB患者的CD30的表达较培养前均明显的增加 (P <0 0 5 ) ;培养后 ,CHB患者CCR5的减少量低于NC ,而CD30的增加量少于NC(P <0 0 5 )。④培养前CHB患者CCR5 /CD30低于NC ,而培养后高于NC(P <0 0 5 ) ,两组培养后CCR5 /CD30均明显低于培养前 (P <0 0 5 )。结论 ①CCR5及CD30目前可作为Th及Tc细胞亚群相对特异性的细胞表面标志物 ;②CHB患者体内CCR5及CD30的异常表达或两者表达的失衡即Th/Tc细胞亚群的失衡与病毒性肝炎的发病

 
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