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缓解后治疗
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  postremission therapy
     DFS of allogeneic hematopoietic stem cell transplantation(HSCT) and intermediate-dose cytarabine/high dose cytarabine(IDAC) groups were better than the group received routine dose cytarabine as postremission therapy(P<0.01).
     采用异基因造血干细胞移植(HSCT)和中或高剂量阿糖胞苷作为缓解后治疗患者的DFS率明显高于接受常规剂量阿糖胞苷者(P<0.01)。
短句来源
     HIGH-DOSE CYTARABINE AS INTENSIVE POSTREMISSION THERAPY FOR ACUTE MYELOGENOUS LEUKEMIA: EFFECT ON LONG-TERM DISEASE-FREE SURVIVAL
     大剂量阿糖胞苷对急性髓细胞白血病缓解后治疗的无病生存影响
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  “缓解后治疗”译为未确定词的双语例句
     Follow-up study of HA-IDAra-C program on after-remission acute myeloid leukemia
     HA-IDAra-C方案对急性髓系白血病缓解后治疗的研究
短句来源
     Conclusion AML with t(8;21) is not a single defined AML subset, and patients with additional chromosome abnormalities have a worse prognosis. HSCT and IDAC could improve the outcome.
     结论t(8;21)AML-M2也存在异质性,有附加染色体异常对预后有不良影响,采用HSCT和中或高剂量阿糖胞苷作为缓解后治疗有利于延长患者生存期。
短句来源
     Long duration of discontinUe drugs,or insufficient intensity of chemotherapy,duplicated use of ATRA and same protocol were major factors causing relapse.
     停药过长、化疗不力、多次重复ATRA或应用同一方案作缓解后治疗,均系引起复发的重要因素。
短句来源
     Methods: Fourteen patients with AML, which were induced to complete remission, were treated with HA-ID-Ara-C program.
     方法 :1 4例AML患者常规诱导达完全缓解后 ,用HA -IDAra-C方案进行缓解后治疗
短句来源
     5)After intensification therapy, 10 of 22 patients received hematological stem cell transplantation(HSCT), include 5 cases of allogeneic HSCT and 5 cases of autogeneic HSCT. All patients maintain disease-free survival from one month to fourteen months
     (7)6/22例Ph~+或BCR/ABL~+-ALL患者中,联合伊马替尼与hyper-CVAD/MA作为缓解后治疗,5例在强化疗后接受了HSCT(2例为同胞相合供者,1例为同胞半相合供者,2例自体移
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     After penicillin was used, his symptoms greatly improved.
     青霉素治疗症状明显缓解
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     no remission within 28days with induction treatment;
     诱导化疗28d未缓解
短句来源
     Both cases were alleviated after nerve releasing.
     经神经松解症状缓解
短句来源
     Edema was relieved with the help of therapy of dehydration and dexamethasone.
     经脱水、激素治疗缓解
短句来源
     ⑦ Therapy and prognosis: 2 LG patients were improved and 2 died.
     W G 经治疗, 多数患者病情缓解;
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  postremission therapy
Therefore, the optimal postremission therapy for AML remains to be defined, and further improvements in treatment strategies are required.
      
This article reviews the results of important trials in which TSC was used as an induction regimen in de novo, relapsed, or refractory acute myelogenous leukemia or as postremission therapy.
      
This finding complicates the evaluation of postremission therapy options, which CCG 2891 also evaluated.
      
Intensification of postremission therapy included multiple courses of high-dose chemotherapy and/or myeloablative therapy followed by stem-cell rescue from either allogeneic or autologous sources.
      
High-dose cytosine arabinoside and daunorubicin postremission therapy in adults with de novo acute myeloid leukemia
      
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Bone marrow findings at the time of complete remission were analyzed in 124 patients with acute leukemia to determine if some variables were predictive for remission duration. Percentage of blasts, promyelocytes (promonocytes or prolymphocytes), erythroid precursors, granulocytes (myelocytes and more mature cells) and lymphocytes and celluarity in the marrow aspirate were analyzed. In addition, DNA contents were measured by flow cytometry in 6 cases to detect the residual leukemic cells in remission marrow and...

Bone marrow findings at the time of complete remission were analyzed in 124 patients with acute leukemia to determine if some variables were predictive for remission duration. Percentage of blasts, promyelocytes (promonocytes or prolymphocytes), erythroid precursors, granulocytes (myelocytes and more mature cells) and lymphocytes and celluarity in the marrow aspirate were analyzed. In addition, DNA contents were measured by flow cytometry in 6 cases to detect the residual leukemic cells in remission marrow and to identify the prognostic significance of the abnormal DNA contents. The data failed to demonstrate any statistically significant difference in remission duration. In order to prolong the remission duration, we consider that the post-remission therapy including consolidation, intensification and maintenance is of great importance.

分析124例急性白血病完全缓解期骨髓象表现及其对缓解期的影响。所用参数为增生程度及原始细胞、早幼粒(幼单、幼淋)细胞、有核红细胞、中幼粒细胞以下粒细胞和淋巴细胞的百分数。另有6例用流式细胞仪检测完全缓解期骨髓单个核细胞的DNA含量,以期发现残存白血病细胞及异常DNA含量的预后意义。结果表明,以上参数对缓解期的长短无明显影响。要延长缓解期,坚持缓解后治疗(巩固、维持和强化)极为重要。

Twenty four cases suriving acute leukemia for more than 3 years in our hospital are reported, among which, 12 cases are of acute lymphatic leukemia and acute nonlymphatic leukemia each, with the longest survival of 17 years. The key to long survival in cases of acute leukemia lies in strong combined chemotherapy given soon after the diagnosis is confirmed. Efforts should be made to achieve complete remission in a short period time, than persistent treatment should be carried out after that, and supporting therapy...

Twenty four cases suriving acute leukemia for more than 3 years in our hospital are reported, among which, 12 cases are of acute lymphatic leukemia and acute nonlymphatic leukemia each, with the longest survival of 17 years. The key to long survival in cases of acute leukemia lies in strong combined chemotherapy given soon after the diagnosis is confirmed. Efforts should be made to achieve complete remission in a short period time, than persistent treatment should be carried out after that, and supporting therapy should be enforced so that patients might prolong their survival or might even achieve complete recovery.

本文报告我院存活3年以上急性白血病24例(急淋与急非淋各12例),存活最长者17年。急白获得长生存期的关键在于确诊后立即给予强有力的联合化疗,争取短期内达CR,之后坚持巩固治疗和缓解后的治疗,加强支持疗法等,可使病人延长生存期,甚至治愈。

In 12 patients of relapsed and refractory acute promyeloeytic leukemia(APL)treated with protocols of mitoxantrone plus cytarabine(Ara-C),with or without etoposide(MAE)or H (Harringtonine)AE,total complete remission(CR)rate was 83%.CR rate reached to 90% in 10 cases of relapsed group.5 patients were reindueed by all-trans retinoic acid(ATRA),among which 3 cases were CR,1 was partial remission(PR)and 1 case was unresponsed.3 relapsed cases were resistance,7 relapsed cases were due to discontinue drugs for 6~22...

In 12 patients of relapsed and refractory acute promyeloeytic leukemia(APL)treated with protocols of mitoxantrone plus cytarabine(Ara-C),with or without etoposide(MAE)or H (Harringtonine)AE,total complete remission(CR)rate was 83%.CR rate reached to 90% in 10 cases of relapsed group.5 patients were reindueed by all-trans retinoic acid(ATRA),among which 3 cases were CR,1 was partial remission(PR)and 1 case was unresponsed.3 relapsed cases were resistance,7 relapsed cases were due to discontinue drugs for 6~22 months(medium 11 months),up to date the CR_2 durations were 1~18 months(medium 6 months).The suppression of bone marrow was the major side effect.Duration of survival was 12~47 months(medium 39 months)so far in 9 cases achieved CR_2,2 cases among them were 3 relapse,1 case was secondary relapse,6 cases were in continued remission.Long duration of discontinUe drugs,or insufficient intensity of chemotherapy,duplicated use of ATRA and same protocol were major factors causing relapse.

本组采用MA/MAE或HAE方案治疗12例复发性难治性急性早幼粒细胞白血病患者,总CR率83%,复发组10例的CR率达90%。5例采用全反式维甲酸(ATRA)作再诱导治疗,其中3例CR,1例PR,1例无效。3例复发系耐药,7例复发因停药6~22个月(中数11个月)。至今CR_2持续期为1~18个月(中数为6个月)。MA(E)方案的主要毒副作用为骨髓抑制,一般均可耐受。9例复发获CR_2者迄今存活12~47个月(中数39个月),其中2例第三次复发,1例第二次复发,6例处于持续缓解中。停药过长、化疗不力、多次重复ATRA或应用同一方案作缓解后治疗,均系引起复发的重要因素。

 
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