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   血液肿瘤细胞 的翻译结果: 查询用时:0.288秒
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血液肿瘤细胞     
相关语句
  hematological tumor cell
     Expression of survivin gene and protein in hematological tumor cell lines
     不同血液肿瘤细胞株survivin基因和蛋白表达及意义的研究
短句来源
     To investigate transcription factor PAX5 expression characteristics in childhood acute leukemic cells, expression levels of PAX5 and CD19 mRNA in 6 hematological tumor cell lines and bone marrow cells of 6 normal children, 58 de novo patients and 4 relapse acute leukemic children, including 39 cases of B-ALL,10 cases of T-ALL and 13 cases of AML, were detected by a real-time RT-PCR.
     为了观察了解儿童急性白血病细胞中转录因子PAX5的表达特性,采用实时定量RT-PCR方法测定了6个血液肿瘤细胞株以及6例正常儿童、58例初发和4例复发急性白血病儿童(其中包括39例B-ALL,10例T-ALL和13例AML)骨髓细胞中PAX5和CD19mRNA的表达水平。
短句来源
     There was different uptake of G3139 among the malligant hematological tumor cell strains, and the uptake in cells derived from monocyte, B lymphocyte and myeloid cell was much higher than that in cells derived from T lymphocyte.
     不同来源的血液肿瘤细胞株摄取G31 39的能力不同 ,单核细胞、B淋巴细胞和髓系粒细胞来源的白血病细胞的摄取能力明显高于T淋巴细胞来源的白血病细胞 ;
短句来源
  haematolological tumor cell
     Expression of the transcription factor PAX5/BSAP in childhood acute leukemic cells and haematolological tumor cell lines
     PAX5/BSAP在儿童急性白血病细胞和血液肿瘤细胞株中的表达研究
短句来源
     Objective To investigate transcription factor PAX5/BSAP expression characteristics in childhood acute leukemic cells and haematolological tumor cell lines.
     目的了解儿童急性白血病细胞和血液肿瘤细胞株中转录因子PAX5/BSAP的表达特性。
短句来源
  hematological tumour cell
     Expression of survivin gene in hematological tumour cell strains
     血液肿瘤细胞株细胞survivin基因表达以及ATRA对NB4细胞株survivin基因表达的调节
短句来源
     It was found that survivin gene was expressed in 11 hematological tumour cell strains (k562, HL-60, U937, HEL, 6T-CEM, NB4, Jurkat, Raji, MUTZ-1, Dami and k562/ADR cell strain).
     不同类型的血液肿瘤细胞株survivin砍NA表达有明显的差异性,Dami与k562,HL币0,Jurkat,MUTZ一1,Raji,6T一CEM;
短句来源
     Expression of Survivin gene in hematological tumour cell lines
     Survivin基因在血液肿瘤细胞株细胞的表达
短句来源
     AIM: To investigate the expression profile of survivin gene in hematological tumour cell strains.
     目的 :检测survivin基因在血液肿瘤细胞株细胞的表达。
短句来源
     Objective To investigate the expression profile of Survivin gene in hematological tumour cell lines.
     目的 探讨 Survivin基因在血液肿瘤细胞株细胞的表达及其可能的机制。
短句来源
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  malignant hematopoietic cells
     Objective To detect the relationship between sensitivity of malignant hematopoietic cells to arsenic trioxide (As 2O 3) and cellular capacity against oxidation.
     目的 探讨血液肿瘤细胞对三氧化二砷 (As2 O3 )的敏感性和细胞抗氧化能力的关系。
短句来源
     Conclusion Intracellular GSH level and/or catalase activity are important factors to determine sensitivity of malignant hematopoietic cells to As 2O 3 induced apoptosis.
     结论 细胞内GSH水平和过氧化氢酶的活性是决定血液肿瘤细胞对As2 O3 敏感性的重要因素。
短句来源
     The relationship between sensitivity to arsenic trioxide and antioxidative capacity of malignant hematopoietic cells
     血液肿瘤细胞对氧化砷的敏感性与其抗氧化能力的关系
短句来源

 

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      malignant hematopoietic cells
    In this international study the reactivity profiles of monoclonal antibodies were analyzed on normal and malignant hematopoietic cells.
          
    Firstly, the expression of CD7 on malignant hematopoietic cells might be related to a distinct level of differentiation within a given disease entity.
          
    Here we show that NPM acts as a cellular p53 negative regulator to protect normal and malignant hematopoietic cells from stress-induced apoptosis.
          
    We have observed that ERG3 is the dominant isoform in normal and malignant hematopoietic cells.
          


    A very useful method,fluorescent(Hoechst33258)staining is improved to detect apoptosis in suspension cultured HL-60,,K562 cells in vitro.The procedure involving cell fixating,making slide,staining and detecting can be finished in 2h,and this allows a survey of several thousand cells by a quick microscopic scan even when the apoptosis rate is extremely low( l%).Consequently,this method should be an easy,fast,and highly reliable system for routine laboratory detecting of apoptosis in suspension cultured...

    A very useful method,fluorescent(Hoechst33258)staining is improved to detect apoptosis in suspension cultured HL-60,,K562 cells in vitro.The procedure involving cell fixating,making slide,staining and detecting can be finished in 2h,and this allows a survey of several thousand cells by a quick microscopic scan even when the apoptosis rate is extremely low( l%).Consequently,this method should be an easy,fast,and highly reliable system for routine laboratory detecting of apoptosis in suspension cultured cancer cells.

    改良了观察血液肿瘤细胞凋亡形态学的荧光染色法。其程序包括细胞固定、、制片、染色、现察等步骤,简单易行;整个细胞凋亡检测过程在2h内即可完成,且检出率极高,甚至在细胞凋亡发生率仅为1%的情况下,仍可快速检出。因此,该染色法具有方便、快速、实用性强的特点。适用于常规实验室细胞凋亡形态学观察。

    Human hematopoietic stem cells, like most somatic cells, lose telomeric DNA upon each cell division, so hematopoietic cells in different stage of development show various telomere length, and then display various pro-liferative potential and repopulation ability. Moreover, the malignant hematopoietic cells also show significantly shorter telomere and higher telomerase activity than those in the normal hematopoietic cells. These findings have implications for the control mechanism of primitive hematopoietic cells'...

    Human hematopoietic stem cells, like most somatic cells, lose telomeric DNA upon each cell division, so hematopoietic cells in different stage of development show various telomere length, and then display various pro-liferative potential and repopulation ability. Moreover, the malignant hematopoietic cells also show significantly shorter telomere and higher telomerase activity than those in the normal hematopoietic cells. These findings have implications for the control mechanism of primitive hematopoietic cells' proliferation, differentiation, maturation and apoptosis, and could provide certain theoretical foundation for researching the pathogenesis, diagnosis and a new therapy strategy for malignant hematopoietic diseases.

    人类造血细胞与大多数体细胞一样,其端粒也随着细胞的每次分裂而不断丧失,因此不同发育阶段的造血细胞以及不同分化阶段的造血细胞其端粒的平均长度是不同的,并显示出相应不同的增殖和分化潜能与支持造血能力。端粒酶虽然在某种程度上能延缓造血干细胞自身端粒缩短的速度,但决不能完全阻止其丢失,并且正常造血细胞与恶性血液肿瘤细胞的端粒长度及其端粒酶活性也存在着明显的差异。这些发现为更深入地探讨正常造血细胞增殖、分化、成熟和凋亡的调控机制以及恶性血液肿瘤的发病机理、诊断和治疗的新策略研究提供了重要的理论依据。

    Objective: To investigate effects of phenylarsine oxide (PAO) on hematopoietic maligant cell lines. Methods: Eight cell lines from hematopoietic malignancies were treated with 0. 01 μmol/L, 0. 05 μmol/L and 0. 1μmol/ L of PAO for different days. Cell viability was assessed by trypanblau exclusion, and the distribution of cellular DNA contents was measured on flow cytometry. Results and Conclusion: PAO had a wider effect spectrum on hematopoietic malignant cell lines in terms of growth inhibition and apoptosis...

    Objective: To investigate effects of phenylarsine oxide (PAO) on hematopoietic maligant cell lines. Methods: Eight cell lines from hematopoietic malignancies were treated with 0. 01 μmol/L, 0. 05 μmol/L and 0. 1μmol/ L of PAO for different days. Cell viability was assessed by trypanblau exclusion, and the distribution of cellular DNA contents was measured on flow cytometry. Results and Conclusion: PAO had a wider effect spectrum on hematopoietic malignant cell lines in terms of growth inhibition and apoptosis induction, and 0. 05 μmol/L and 0. 1μmol/L of PAO could inhibit growth of some hematopoietic malignant cells with or without apoptosis induction. However, cell lines from different origins had the different sensitivity to PAO.

    目的:了解氧化酚砷(Phenylarsine oxide, PAO)对血液肿瘤细胞系的影响。方法: 8种血液肿瘤系经0.01μmol/L、0.05μmol/L和0.1μmol/L的PAO处理达一定时间后,经台盼蓝排除法计数细胞活力和应用流式细胞仪检测细胞DNA含量分布。结果和结论:在生长抑制和诱导凋亡方面,PAO对血液肿瘤细胞的效应谱相对较广,0.05μmol/L和0.1μmol/L的PAO能抑制某些血液肿瘤细胞的生长,并诱导其凋亡。但是,不同来源的血液肿瘤细胞系对PAO的敏感性不完全相同。

     
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