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老年肾病综合征
相关语句
  elderly nephrotic syndrome
     Clinical analysis of 21 cases of acute renal failure in elderly nephrotic syndrome
     老年肾病综合征并发急性肾功能衰竭21例临床分析
短句来源
     Objective To explore the clinical feature,pathology and prognosis in elderly nephrotic syndrome(NS) with acute renal failure(ARF).
     目的 深入探讨老年肾病综合征 (NS)并发急性肾功能衰竭 (ARF)的临床、病理及预后。
短句来源
  “老年肾病综合征”译为未确定词的双语例句
     Clinical study of infection in nephrotic syndrome in the elderly
     老年肾病综合征并发感染的临床研究
短句来源
     Steroid and immunosuppressive agent were effective,with the relief rate of 47 8%,the effective rate of 30 4% and the uneffective rate 21 7%.
     老年肾病综合征病人用激素或激素加免疫抑制剂治疗的缓解率为 47 8% ,有效率为 3 0 4% ,未缓解率为 2 1 7%。
短句来源
     Clinical and Pathological Analyses in Nephrotic Syndrome of Elder
     老年肾病综合征临床和病理分析
短句来源
     Nephrotic syndrome in the elderly:clinical and pathological analyses
     老年肾病综合征的临床表现和病理类型分析
短句来源
     Results 513 cases of nephrotic syndrome were diagnosed in an adult population,61(11 9%)of whom were older than 60 years at the first onset.
     结果  住院成人肾病综合征病人共 5 13例 ,其中老年肾病综合征 61例 ,占 11 9%。
短句来源
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  相似匹配句对
     Das nephrotische Syndrom
     肾病综合征
短句来源
     Clinical and Pathological Analyses in Nephrotic Syndrome of Elder
     老年肾病综合征临床和病理分析
短句来源
     Management of Idiopathic Nephrotic Syndrome in Children
     肾病综合征的治疗
短句来源
     Clinical study of infection in nephrotic syndrome in the elderly
     老年肾病综合征并发感染的临床研究
短句来源
     Nephrotic syndrome in the elderly:clinical and pathological analyses
     老年肾病综合征的临床表现和病理类型分析
短句来源
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OBJECTIVE To characterize P selectin expression by renal tissue and peripheral blood in old patients with nephrotic syndrome. METHODOLOGY Renal biopsy specimen and peripheral bloods from 26 old patients with nephrotic syndrome were collected. Renal tissue from 8 normal kidneys and peripheral bloods from 30 age matched normal volunteers were used as control. Renal frozen sections were coated with fluorescent isothiocyanate conjugated monoclonal anti CD62P antibody. The number of platelets expressing P selectin...

OBJECTIVE To characterize P selectin expression by renal tissue and peripheral blood in old patients with nephrotic syndrome. METHODOLOGY Renal biopsy specimen and peripheral bloods from 26 old patients with nephrotic syndrome were collected. Renal tissue from 8 normal kidneys and peripheral bloods from 30 age matched normal volunteers were used as control. Renal frozen sections were coated with fluorescent isothiocyanate conjugated monoclonal anti CD62P antibody. The number of platelets expressing P selectin were counted by flow cytometry. RESULTS The number of platelets expressing p selectin were significantly increased in old patients with nephrotic syndrome as compared with the normal controls. Glomerular P selectin staining was found in 22 of 26 old patients with nephrotic syndrome, while the staining was negative in 8 normal renal tissues. The intensity of glomerular staining was correlated with the amount of proteinuria. CONCLUSION The increased expression of P selectin in glomeruli and peripheral platelets may contribute to glomerular pathology in old patients with nephrotic syndrome.

目的:探讨粘附分子P选择素(CD62P)在老年肾病综合征(NS)中的变化。方法:采用流式细胞术和直接免疫荧光标记单克隆抗体对老年NS患者周围血和肾活检组织进行了CD62P表达的研究。结果:①26例老年NS患者周围血CD62P表达量较正常组显著增高(P<0.01);②肾组织中显示CD62P表达22例(84.62%),表达部位常见于肾小球系膜区、血膜袢,其次为肾小管、间质小血管及球囊壁。③CD62P在周围血表达水平与肾组织表达程度呈显著正相关(P<0.01),血、肾组织的表达与患者尿蛋白定量呈正相关(P<0.05)。结论:CD62P在老年NS患者肾组织和周围血中表达增强,提示其在NS发病机制中具有重要作用

Serum lipid levels in 63 elderly chronic renal failure

目的探讨血清脂质水平对老年肾脏病的影响。方法测定了63例老年慢性肾功能衰竭、44例老年慢性肾功能衰竭血液透析及36例老年肾病综合征病人血清脂质代谢的各项指标,并与正常健康人进行比较。结果老年慢性肾衰病人脂质代谢异常,表现为TG、LDL增高,HDL、ApoAI、ApoAI/ApoB降低,TC、ApoB正常;老年慢性肾衰血液透析组TG、LDL增高,HDL、ApoAI、ApoB、ApoAI/ApoB降低,TC正常;老年肾病综合征CHO、TG、LDL、ApoB增高,HDL、ApoAI、ApoAI/ApoB降低。各组与正常健康组比较均有差异。结论对老年肾脏疾病血清脂质含量的检测,有助于通过膳食及降脂药物的治疗减轻肾损害,消除心血管并发症的危险因素。

Objective To understand the nephrotic syndrome in the elderly. Methods clinical and pathological analyses were performed in 61 patients with nephrotic syndrome,whose ages were over 60 between the beginning of 1980 and the end of 1999 in PUMC hospital. Results 513 cases of nephrotic syndrome were diagnosed in an adult population,61(11 9%)of whom were older than 60 years at the first onset.Among them,49 cases (80 3%),had chronic glomerulonephitis...

Objective To understand the nephrotic syndrome in the elderly. Methods clinical and pathological analyses were performed in 61 patients with nephrotic syndrome,whose ages were over 60 between the beginning of 1980 and the end of 1999 in PUMC hospital. Results 513 cases of nephrotic syndrome were diagnosed in an adult population,61(11 9%)of whom were older than 60 years at the first onset.Among them,49 cases (80 3%),had chronic glomerulonephitis 7 cases(11 5%) had diabetic nephropathy.The clinical features presented little difference from those of younger patients,although 54 1% of the patients manifested anemia,18% showed acute renal insufficiency and 32 8% displayed chronic renal insufficiency.Mesangial glomerulonephritis is the particularly common type in biopsy.Damage to the interstitium in the kidney was often observed.Steroid and immunosuppressive agent were effective,with the relief rate of 47 8%,the effective rate of 30 4% and the uneffective rate 21 7%. Conclusions The nephrotic syndrome in elderly patients is not common and the clinical features differ little from those of younger patients,although complicated anemia,inpotentially acute renal insufficiency and chronic renal insufficiency are more common than those in the young.The ratio of infection are higher than that in their younger counterparts.Chronic glomerulonephritis is the most common cause of the nephrotic syndrome in the elderly,mesangial glomerulonephritis is particularly common in pathological detection.Nephrotic syndrome in the elderly responded well to corticosteroids and immunosuppressive agents.

目的 进一步了解老年肾病综合征的临床表现和病理特点。  方法  对北京协和医院 1980~ 1999年底住院老年肾病综合征病人进行临床表现和病理类型分析。  结果  住院成人肾病综合征病人共 5 13例 ,其中老年肾病综合征 61例 ,占 11 9%。原发病为原发性肾小球肾炎者 49例 ,占 80 3 % ,糖尿病肾病者 7例 ,占 11 5 %。临床表现以浮肿、血尿为主 ,贫血的发生率为 5 4 1% ,慢性肾功能不全 (CRF)为 3 2 8%。肾活检发现 ,在非糖尿病肾病中 ,系膜增殖性肾小球肾炎最常见 ,其次是局灶增殖性肾小球肾炎 ,并且肾间质纤维化比较多见 ( 15 /2 1)。老年肾病综合征病人用激素或激素加免疫抑制剂治疗的缓解率为 47 8% ,有效率为 3 0 4% ,未缓解率为 2 1 7%。一般激素或激素加免疫抑制剂效果较好 ,单用雷公藤多甙效果不如前者。合并感染者占 2 3 %。  结论  在肾病综合征病人中老年人所占比例并不高 ,其临床表现与年轻人的肾病综合征相似 ,但合并贫血、急性肾功能不全 (ARF)、CRF和感染的比例较高 ,...

目的 进一步了解老年肾病综合征的临床表现和病理特点。  方法  对北京协和医院 1980~ 1999年底住院老年肾病综合征病人进行临床表现和病理类型分析。  结果  住院成人肾病综合征病人共 5 13例 ,其中老年肾病综合征 61例 ,占 11 9%。原发病为原发性肾小球肾炎者 49例 ,占 80 3 % ,糖尿病肾病者 7例 ,占 11 5 %。临床表现以浮肿、血尿为主 ,贫血的发生率为 5 4 1% ,慢性肾功能不全 (CRF)为 3 2 8%。肾活检发现 ,在非糖尿病肾病中 ,系膜增殖性肾小球肾炎最常见 ,其次是局灶增殖性肾小球肾炎 ,并且肾间质纤维化比较多见 ( 15 /2 1)。老年肾病综合征病人用激素或激素加免疫抑制剂治疗的缓解率为 47 8% ,有效率为 3 0 4% ,未缓解率为 2 1 7%。一般激素或激素加免疫抑制剂效果较好 ,单用雷公藤多甙效果不如前者。合并感染者占 2 3 %。  结论  在肾病综合征病人中老年人所占比例并不高 ,其临床表现与年轻人的肾病综合征相似 ,但合并贫血、急性肾功能不全 (ARF)、CRF和感染的比例较高 ,最常见的病因是慢性肾小球肾炎 ,其病理类型以系膜增殖型肾小球肾炎最常见 ,其次是局灶增殖型肾小球肾炎。老年肾病综合征患者对激素或激素加免疫抑制剂治疗的反应尚可。

 
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