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儿童难治性肾病综合征
相关语句
  childhood refractory nephrotic syndrome
     The Application of Cyclosporine A in Childhood Refractory Nephrotic Syndrome
     环孢霉素A在儿童难治性肾病综合征的应用
短句来源
  children intractable nephrotic synrdrome
     Therapy Development of Children Intractable Nephrotic Synrdrome
     儿童难治性肾病综合征的治疗进展
短句来源
  children with obstinate nephrotic syndrome
     The effect of CTX pulse therapy on the plasma IgG in children with obstinate nephrotic syndrome
     儿童难治性肾病综合征环磷酰胺冲击治疗对血清IgG的影响
短句来源
     Objective To explore the therapeutic effect of CTX on the children with obstinate nephrotic syndrome (ONS) and the relationship between the level of plasma IgG before and after CTX pulse therapy and the therapeutic effect. Method The serum IgG was detected by immune transmission before treatment after the children with nephrotic syndrome were (NS) diagnosed.
     目的 :探讨环磷酰胺 (CTX)治疗儿童难治性肾病综合征 (ONS)的疗效及治疗前后血清IgG水平与其治疗效应之间的关系。
短句来源
  “儿童难治性肾病综合征”译为未确定词的双语例句
     Analysis of the Pathology and Clinical Features on Refractory Nephrotic Syndrome in 34 Children
     儿童难治性肾病综合征34例临床与病理分析
短句来源
     Damage of Tubulointerstitium with in Children the Persistent Nephrotic Syndrome
     儿童难治性肾病综合征小管间质损害的分析
短句来源
     Objective:To investigate the clinical therapeutic effectiveness of intravenous immunoglobulin(IVIG) in the treatment of refractory nephritic syndrome(RNS) in children.
     目的:探讨静脉注射用免疫球蛋白(IVIG)对儿童难治性肾病综合征(RNS)的临床疗效。
短句来源
     STUDIES ON REFRACTORY NEPHROTIC SYNDROME IN CHILDRN—CLINICAL ANALYSIS OF 95 Cases
     儿童难治性肾病综合征的探讨95例临床分析
短句来源
     Objective To explore the curative effect and long-term sexual gland impairment of continuous stosstherapy with a large dose of cyclophosphamide(CTX) in treatment of nephrotic syndrome(NS) in children in Zhuang nationality.
     目的探讨大剂量环磷酰胺(CTX)冲击治疗壮族儿童难治性肾病综合征(肾病)的疗效及远期对性腺的损害。
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    This paper is to present the study of the CTX pulse therapy for 30 cases of CRNS. with a curative effect of ninty precent in the near future,Twenty of the thivty cases got the curative ef- fect in the first period of tveatmoent,twenty一six of the 30 cases in the second period and twenty一sev- en of 30 cases in the third one. The side effect in the near future shows that three cases have a shght tri- chomadesis,two cases with nauses and vomiting and one case WBC reduced to 2. 8X 1Oa/L. The resulf of the tveatment...

    This paper is to present the study of the CTX pulse therapy for 30 cases of CRNS. with a curative effect of ninty precent in the near future,Twenty of the thivty cases got the curative ef- fect in the first period of tveatmoent,twenty一six of the 30 cases in the second period and twenty一sev- en of 30 cases in the third one. The side effect in the near future shows that three cases have a shght tri- chomadesis,two cases with nauses and vomiting and one case WBC reduced to 2. 8X 1Oa/L. The resulf of the tveatment shows that CTX一PT is an effective method to cure RNS with less side effect

    儿童难治性肾病综合征30例。本文用环磷酰胺冲击(CTX一PT)治疗。结果:近期疗效90%,20/30例在第一疗程有效,26/30例在第二疗程有效,27/30在第三疗程有效。近期副作用:轻度脱发3例,恶心、呕吐2例,1例外周血WBC降为2.8X109/L结果表明:CTX一PT不失为一种治疗RNS有效、副作用少的方法。

    In order to approach the therapy development of children intractable nephrotic syndrome,the treatment methods of this disease were summarized. Adrenocortical hormone,Methyprednison,Cytotoxin Drug,CsA are commonly used in clinical practice.CTX is one of the wide used drugs among cytotoxin type.Stosstherapy with methyprednison is now put to clinical use more and more recently.The use of CsA is limited because of its high price.The other treatment include anticogulant therapy,immunoemhaement therapy,light quantum...

    In order to approach the therapy development of children intractable nephrotic syndrome,the treatment methods of this disease were summarized. Adrenocortical hormone,Methyprednison,Cytotoxin Drug,CsA are commonly used in clinical practice.CTX is one of the wide used drugs among cytotoxin type.Stosstherapy with methyprednison is now put to clinical use more and more recently.The use of CsA is limited because of its high price.The other treatment include anticogulant therapy,immunoemhaement therapy,light quantum therapy.

    为探讨儿童难治性肾病综合征的治疗进展 ,笔者综述近年来儿童难治性肾病综合征的治疗方法。结果以肾上腺皮质激素、甲基强的松龙、细胞毒药物、环孢菌素 A治疗常见 ,其中细胞毒药物中以环磷酰胺冲击治疗应用广泛 ,甲基强的松龙冲击治疗近年应用渐多 ,环孢菌素 A由于价格昂贵 ,限临床使用 ;其它方法有抗凝疗法、免疫增强疗法、光量子疗法等

    Objectives: The aim of the study was to evaluate the therapeutic effects of 6 mercaptopurine in the treatment of refractory childhood nephrotic syndrome (NS). Methods: According to the varieties of NS, 6 mercaptopurine (2 mg/kg body weight daily) combined with corticosteroid or 6 mercaptopurine (2 mg/kg body weight daily) alone after tapering of steroids were given to 28 consecutive children with primary NS in our hospital. Results: One month after the use of 6 mercaptopurine, proteinuria was decreased....

    Objectives: The aim of the study was to evaluate the therapeutic effects of 6 mercaptopurine in the treatment of refractory childhood nephrotic syndrome (NS). Methods: According to the varieties of NS, 6 mercaptopurine (2 mg/kg body weight daily) combined with corticosteroid or 6 mercaptopurine (2 mg/kg body weight daily) alone after tapering of steroids were given to 28 consecutive children with primary NS in our hospital. Results: One month after the use of 6 mercaptopurine, proteinuria was decreased. The duration of improvement was 9~28 days, with mean duration of 17 days. Over all effective rate was 85.7%. Among different varieties of NS, the best therapeutic effect was noted in steroid dependent children; the better therapeutic effect in steroid resistant children; and good therapeutic effect in frequently relapsing children. The effective rates were 100%, 84.6%, 81.8% respectively. All the pathological varieties of 28 children were confirmed by renal biopsy. The better therapeutic effects were noted in slight mesangial proliferative glomerulonephritis (MsPGN) and minimal change nephrotic syndrome (MCNS). The less therapeutic effect was noted in membranoproliferative glomerulonephritis (MPGN). Their therapeutic effective rates were 92.9%, 80%, 66.7% respectively. Unfortunately, drug induced aplastic anemia was seen in 2 cases. Slight gastrointestinal reactions were present in 6 cases. There were no side reaction on the gonad. Conclusions: The great difference in the therapeutic effects is related to the different pathologic varieties of NS. With regard to the treatment of refractory NS in children, the pathological varieties should be confirmed by renal biopsy as soon as possible. Based on the renal biopsy, 6 mercaptopurine can be considered in the treatment of MsPGN and MCNS. As a result, relapses could be reduced; the duration of remission could be prolonged, and the side reactions from steroid treatment could be avoided. The use of 6 mercaptopurine for the treatment of refractory NS is one of the effective therapy.

    目的 :儿童难治性肾病是原发性肾病综合征中激素耐药、激素依赖、频繁复发病例的总称 ,但目前尚缺乏有效的治疗措施 ,6 巯基嘌呤是治疗难治性肾病综合征的有效药物之一。国外有学者曾报道与泼尼松联合应用能减少肾病复发 ,延长缓解期。但国内未见将 6 巯基嘌呤用于儿童难治性肾病的治疗 ,作者重点探讨 6 巯基嘌呤在儿童难治性肾病综合征中的治疗作用与不良反应。 方法 :对该科住院的 2 8例原发性肾病综合征患儿 ,根据不同肾病类型 ,在院外已使用激素者 ,如为激素耐药型与频繁复发型入院后逐渐减用激素 ,先减至原剂量隔日疗法 ,减量的同时加用 6 巯基嘌呤 (2mg/kg·d-1)、疗程 1年 ,激素每 2~ 4周减 5~ 10mg ,减至隔天 0 .5mg/kg维持 1年 ;如为激素依赖型入院后继用激素 (2mg/kg·d-1) ,同时加用 6 巯基嘌呤 (2mg/kg·d-1)、疗程 1年 ,待肾病缓解后 ,激素逐渐减量 ,具体方法同激素耐药型和频繁复发型。 结果 :经 6 巯基嘌呤治疗 1个月后 ,患儿尿蛋白明显减少 ,起效时间为9~ 2 8天 ,平均 17天 ,总有效率为 85 .7%。在...

    目的 :儿童难治性肾病是原发性肾病综合征中激素耐药、激素依赖、频繁复发病例的总称 ,但目前尚缺乏有效的治疗措施 ,6 巯基嘌呤是治疗难治性肾病综合征的有效药物之一。国外有学者曾报道与泼尼松联合应用能减少肾病复发 ,延长缓解期。但国内未见将 6 巯基嘌呤用于儿童难治性肾病的治疗 ,作者重点探讨 6 巯基嘌呤在儿童难治性肾病综合征中的治疗作用与不良反应。 方法 :对该科住院的 2 8例原发性肾病综合征患儿 ,根据不同肾病类型 ,在院外已使用激素者 ,如为激素耐药型与频繁复发型入院后逐渐减用激素 ,先减至原剂量隔日疗法 ,减量的同时加用 6 巯基嘌呤 (2mg/kg·d-1)、疗程 1年 ,激素每 2~ 4周减 5~ 10mg ,减至隔天 0 .5mg/kg维持 1年 ;如为激素依赖型入院后继用激素 (2mg/kg·d-1) ,同时加用 6 巯基嘌呤 (2mg/kg·d-1)、疗程 1年 ,待肾病缓解后 ,激素逐渐减量 ,具体方法同激素耐药型和频繁复发型。 结果 :经 6 巯基嘌呤治疗 1个月后 ,患儿尿蛋白明显减少 ,起效时间为9~ 2 8天 ,平均 17天 ,总有效率为 85 .7%。在不同的肾病类型中 ,激素依赖型疗效最好 ,依次为激素耐药型、频繁复发型 ,其有效率分别为 10 0 %、84 .6 %、81.8%。 2 8例均经肾活检明确病理类型 ,其病理类型与疗效的关系 ,以M

     
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