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   n-myc 的翻译结果: 查询用时:0.02秒
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儿科学
眼科与耳鼻咽喉科
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nmyc
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  n-myc
     The results also indicated that the simultaneous amplification rate of L-myc and N-myc, N-myc and C-myc, C-myc and L-myc was 16% (6/38), 26% (10/38), 16%(6/38)respectively.
     结果还显示:L-myc和N-myc同时扩增占16%(6/38),N-myc和C-myc同时扩增占26%(10/38),而C-myc和L-myc同时扩增占16%(6/38),没有一例三种基因同时扩增。
短句来源
     Relation Among DNA Content,N-myc Gene Amplification and the Clinical Prognosis
     小儿神经母细胞瘤DNA含量、N-myc基因扩增与临床预后的关系
短句来源
     mRNA Expression of N-myc Gene, IGF II Gene in Wilms'Tumor
     肾母细胞瘤N-myc、IGFⅡ基因mRNA的表达
短句来源
     The results reveal:the mortality of patients with N-myc gene amplification(7/10)was higher than those without N-myc gene amplification(1/8);
     结果表明,有N-myc基因扩增的死亡率(7/10)明显高于无扩增的(1/8);
短句来源
     C-myc and N-myc were amplified in all emtastasized lymph node of 10 ovarian carcinoma, L-myc was in only 2. No amplification of myc gene family was found in benign tumor and normal tissue.
     在淋巴结转移的10例卵巢癌标本中,C-myc与N-myc全部扩增,L-myc扩增只有2例,良性肿瘤及正常组织均未有扩增。
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  n myc
     Results Amplification of N myc oncogene was found in 24 of 25 cases (96.0%). The N myc copy number in oculometastasis group (51.3±32.4) was higher than that in non oculometastasis group (4.3±2.8) ( P <0.05), and the 2 year survival rate of the former was significantly lower than that of the latter ( P <0.05).
     结果25例中有24例(96%)出现N-myc扩增,眼部转移组平均拷贝数(51.3±32.4)显著高于无眼部转移组的平均拷贝数(4.3±2.8),P<0.05,且前者两年生存率明显低于后者。
短句来源
     Objective To study the effects of amplification of N myc oncogene on the oculometastasis and prognosis of neuroblastoma (NB).
     目的通过定量研究小儿神经母细胞瘤(NB)N-myc基因扩增倍数,观察NB眼部转移以及与预后的关系。
短句来源
     The multiples of amplification were 2.1 7.3 In cervical metastasis lymph nodes, one case had C myc amplification and one had amplification of mixed band of N myc and L myc.
     在颈淋巴结转移癌中有1例C-myc扩增,1例N-myc和L-myc融合带扩增。
短句来源
  “n-myc”译为未确定词的双语例句
     To study the amplification rate of myc gene family in ovarian carcinoma tissues. Methods: In this study, PCR combined with polyacrylamide gel electrophoresis and laser scanning techniques was employed to test myc gene family in 38 ovarian carcinom, 20 paracarcinoma, 4 ovarian benign epithelial tumor, 2 normal ovarian tissues.
     本研究采用聚合酶链反应(PCR)结合中性聚丙烯酰胺凝胶电泳和激光扫描技术,对38例卵巢癌、20例癌旁组织、4例卵巢良性上皮性肿瘤及2例正常卵巢组织进行myc基因家族检测,发现在卵巢癌组织中C-myc、N-myc、L-myc扩增率分别为47%、42%、42%。
短句来源
     Methods The authors detected the bone marrow and metastasized tumor in 25 cases of NB in stage Ⅳ with differential polymerase chain reaction, among whom 15 had oculometastasis.
     方法选择25例Ⅳ期NB患儿(有眼部转移15例、无眼部转移10例)做骨穿,有眼部转移者并取转移灶组织,用内参照差示聚合酶链反应(PCR)的方法确定NB细胞的N-myc拷贝数。
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  nmyc
Fluorescence in situ hybridization combined with immunofluorescent staining for rapid detectionof Nmyc amplification in neurobla
      
Fluorescence in situ hybridization was applied with fluorescent probes specific for Nmyc genes afterwards.
      
Results: Fluorescence in situ hybridization can be combined with immunofluorescent staining in detecting Nmyc amplification in neuroblastoma patients.
      
Conclusion: The technique described allows search of tumor cells in the bone marrow as well as detection of Nmyc amplification in interphase nuclei.
      
Amplification of the NMYC gene was detected in six patients with hyperdiploid tumors, two of whom were considered resistant to primary treatment.
      
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To determine the association of fragile sites with leukemias and lymphomas,we examined 22 patients with leukemia or lymphoma (6 Hodgkin lymphomas,6 non-Hodgkin lymphomas,5 acute lymphocytic leukemia,3 acute nonlymphocytic leukemia,2 lymphosarcoleukemia) and 15 normal controls ranging in age from 4 to 56 years.The results were: (1) The average chromosome structural aberration rate of patients(12.98%) was much higher than that of the control group(0.73%).Fifteen cancer patients carried fragile sites,12 of them...

To determine the association of fragile sites with leukemias and lymphomas,we examined 22 patients with leukemia or lymphoma (6 Hodgkin lymphomas,6 non-Hodgkin lymphomas,5 acute lymphocytic leukemia,3 acute nonlymphocytic leukemia,2 lymphosarcoleukemia) and 15 normal controls ranging in age from 4 to 56 years.The results were: (1) The average chromosome structural aberration rate of patients(12.98%) was much higher than that of the control group(0.73%).Fifteen cancer patients carried fragile sites,12 of them carried multiple fragile sites,but none of the controls carried any.There was a statistically significant difference between the two groups (P<0.005).(2) These patients carried 21 autosomal fragile sites (including 14 constitutive fragile sites and 7 heritable fragile sites): 1q44,2q11,2q23,2q37,3p14,4q31,5q31,6q26,8q22,8q24,9q13,10q22,10q23,10q25,11q13,12q13,13q34,14q13,14q24,16p12 and 16q22.(3) Eight breakpoints were located at the bands where oncogenes exist: 1p31 and Blym-1,2p23 and Nmyc,6q23 and myb,8q22 and mos.8q24 and myc,11q13 and bcl-1,15q26 and fes,17q21 and erbA.(4) Four breakpoints were near the fragile sites: 1p32 near fra(1p31),2p23 near fra(2p24),7p15 near fra(7p14),7q22 near fra(7q21).One breakpoint(1p12) was near the Nras(lp13).Five of the fragile sites (8q22,11q13,12q13,16p12 and 16q22) correspond with cancer breakpoints.The role of fragile sites in carcinogenesis is not yet known,but according to our results the association of fragile sites with leukemias and lymphomas is evident which deserves further investigation.

对22例白血病、淋巴瘤病人和15例正常人进行了外周血淋巴细胞染色体脆性部位检测。结果表明,病人组的染色体畸变率、脆性部位检出率显著高于正常对照。通过G显带能准确定位的94个断点中包括了21种常染色体脆性部位,8个与癌基因在同一区带的断点。以上结果提示脆性部位同白血病、淋巴瘤之间有一定的相关。

The mRNA expression of N-myc gene and insulinlike grouwth factor-Ⅱ(IGF Ⅱ) gene were studied in 13 cases with Wilms'tumor.In DNA- RNA Northern hybridization, expression of Nmyc mRNA was found in 12 tumors and IGF Ⅱ mRNA in 11 tumors. Higher expression of ICFⅡand mRNA was observed in most tumors with poor differentiation. The results revealed that the N-myc gene and IGF II gene are probably involved in the development of wilms'tumor.

应用Northernblot杂交,研究13例肾母细胞瘤N-myc癌基因和类胰岛素生长因子Ⅱ(IGFⅡ)基因mRNA的表达,发现12例N-mycmRNA的表达增强,11例有明显的IGFⅡmRNA的表达,分化较差的病,IGFⅡmRNA多为高表达,提示肾母细胞瘤的发生发展过程中,可能也涉及癌基因和生长因子基因的异常。

A comprehensive study of geochemistry was made on a series of the Jinning period (1. 0~0. 75Ga) igneous rocks from the Wudang region, South Qinling Orogenic belt (SQOB). It shows that the volcanics of Wudang Gp, aged ca. 1. 0-0. 95 Ga, have the affinities of arc magmas , and could be compared, in terms of geochemistry and ages, with those from the adjacent Xixiang Gp located at the northern margin of the Yangtze craton (NMYC) and Mogouxia volcanics from SQOB in Shanxi province. Yaolinghe volcanics and...

A comprehensive study of geochemistry was made on a series of the Jinning period (1. 0~0. 75Ga) igneous rocks from the Wudang region, South Qinling Orogenic belt (SQOB). It shows that the volcanics of Wudang Gp, aged ca. 1. 0-0. 95 Ga, have the affinities of arc magmas , and could be compared, in terms of geochemistry and ages, with those from the adjacent Xixiang Gp located at the northern margin of the Yangtze craton (NMYC) and Mogouxia volcanics from SQOB in Shanxi province. Yaolinghe volcanics and Wudang mafic dikes, which emplaced into both Wudang and Yaolinh Gps, share the magma characteristics of the continental rift, and are thought to be the equivalents of Tiechanshan alkaline volcanics and Wangjiangshan mafic swarms from the NMYC, which were radiometriolly dated as ca. 0. 82-0. 78 Ga. The similar experience in tectonic evolution from subduction zone transforming to continental rifting in the two regions indicates that the NMYC and SQOB belong to a unigue continental block, even though the later one is earmarked of strong deformation due to the Phanerozoic orogeny. TDM model ages of ca. 1. 2~0. 9 Ga and high positive ENd values for the Neoproterozoic igneous rocks of the Wudang region demonstrate that the Jinning events played extremely significant role in both crust growth and lithosphere evolution of the regiona.

对南秦岭武当地区武当群火山岩、基性侵入岩墙群和耀岭河群火山岩系统的元素和Nd同位素地球化学研究表明,武当群火山岩为形成于约1.0~0.9Ga的新元古代陆缘岛弧火山岩,而耀岭河群火山岩与武当地区基性侵入岩墙群为0.82~0.78Ga形成的大陆裂谷型同源岩浆岩;它们分别可与扬子克拉通北缘西乡群和南秦岭陕西境内的镇安磨沟峡火山岩、扬子克拉通北缘的火地垭群铁船山组碱性火山岩和望江山基性侵入岩群相对比,揭示出南秦岭与扬子克拉通北缘于晋宁期属统一的陆块。扬子克拉通北缘和南秦岭大量的新元古代岩浆岩所具有的1.2~0.9Ga Nd同位素模式年龄和较高的εNd正值等特征表明,晋宁期是扬子克拉通地壳增生和大陆岩石圈演化的重要时期之一。

 
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