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前列腺癌患者
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  patients with prostate cancer
     Changes of serum T-PSA, F-PSA and F/T ratio in patients with prostate cancer and its clinical significance
     前列腺癌患者血清T-PSA、F-PSA水平和F/T比值变化及临床意义
短句来源
     while in 69 patients with prostate cancer patients, total, free PSA and the ratio were ( 136.09 ± 198.02 )μg/L,( 13.74 ± 24.11 )μg/L, ( 0.11 ± 0.03 ) respectively,and the differences were obvious.
     69例前列腺癌患者TRSA,FPSA分别为(136.09±198.02)μg/L,(13.74±24.11)ug/L,明显高于正常男性(P<0.01),F/T比值为(0.11±0.03),明显低于正常男性(P<0.01)。
短句来源
     Results The mean values of (F/T)/PSAD were significantly lower for patients with prostate cancer in different PSA levels (<4.0,4.0—,10.1—,>20.0 μg/L), when compared with benign prostate hypertrophy patients. This difference has arrived statistical significance (P<0.05).
     结果不同血清PSA水平(<4.0,4.0~,10.1~和>20.0μg/L)的前列腺癌患者的(F/T)/PSAD值与良性前列腺增生患者比较,差异有统计学意义(P<0.05);
短句来源
     Detection of DD3 mRNA in peripheral blood of patients with prostate cancer and its clinical significance
     前列腺癌患者外周血DD3 mRNA的检测及临床意义
短句来源
     Quantitative detection of differential display code 3 mRNA in peripheral blood of patients with prostate cancer
     外周血差异显示编码3mRNA定量检测在前列腺癌患者诊断与治疗监测中的初步应用
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  prostate cancer patients
     Results Serum PSA level increased with GS for prostate cancer patients(r0.369,P<0.001).
     结果前列腺癌患者GS越高,血清PSA水平越高(r=0.369,P<0.001)。
短句来源
     The prostate cancer patients with GSTM1 null genotype had lower onset age (mean,68.1±8.3 years) than those with GSTM1 genotype (mean, 71.9±7.4 years)( P =0.031).
     GSTM1基因缺失型前列腺癌患者的平均年龄 [( 6 8.1± 8.3)岁 ]低于GSTM1未缺失的患者[( 71.9± 7.4 )岁 ,P =0 .0 31]。
短句来源
     while in 69 patients with prostate cancer patients, total, free PSA and the ratio were ( 136.09 ± 198.02 )μg/L,( 13.74 ± 24.11 )μg/L, ( 0.11 ± 0.03 ) respectively,and the differences were obvious.
     69例前列腺癌患者TRSA,FPSA分别为(136.09±198.02)μg/L,(13.74±24.11)ug/L,明显高于正常男性(P<0.01),F/T比值为(0.11±0.03),明显低于正常男性(P<0.01)。
短句来源
     Test result of 35 normal males was (1.45±1.42) μg/L (±s) and that of 11 prostate cancer patients was (26±27.2)μg/L.
     11例前列腺癌患者血清PSA的范围(x±s)为(26±27.2)μg/L。
短句来源
     The expression of prostate cancer specific gene DD3 in peripheral blood of prostate cancer patients
     前列腺癌特异性基因DD3在前列腺癌患者外周血中表达的意义
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  “前列腺癌患者”译为未确定词的双语例句
     Results The ADC of lymph nodes was significantly greater in patients with benign prostate hyperplasia [(2.282±0.573)×10-3 mm2/s] than that with prostate cancer [(1.607±0.256)×10-3 mm2/s)](P=0.000).
     结果良性前列腺增生患者淋巴结的平均ADC值[(2.282±0.573)×10-3mm2/s]明显大于前列腺癌患者[(1.607±0.256)×10-3mm2/s](P=0.000)。
短句来源
     The ADC between lymph nodes with short axis smaller than 1.0 cm [(1.602±0.267)×10-3 mm2/s] and that with short axis greater than 1.0 cm [(1.610±0.254)×10-3 mm2/s] in patients of prostate cancer showed no statistical significance (P=0.459).
     前列腺癌患者短径<1.0cm的淋巴结[(1.602±0.267)×10-3mm2/s]与≥1.0cm淋巴结的ADC值[(1.610±0.254)×10-3mm2/s]无显著性统计学差异(P=0.459)。
短句来源
     No signi ficant difference was seen in the mean ADC values of the bladder between the nor mal group (1.29±0.30)×10~-3 mm~2/s and the PCa group (1.27±0.21)×10~ -3 mm~2/s (t=1.15, P=0.48).
     前列腺癌患者膀胱的ADC值为(1.27±0.21)×10-3mm2/s,对照组膀胱ADC值为(1.29±0.30)×10-3mm2/s,2组之间差异无统计学意义(t=1.15,P=0.48)。
短句来源
     Methods 61 patients clinical data was analyzed retrospectively.
     方法 回顾性分析61 例前列腺癌患者的临床资料。
短句来源
     Methods The conventional histopathological, Gleason grading, and P504s, p63 and 34βE12 immunohistochemistry(SP method) were applied in 71 cases of prostate adenocarcinoma.
     方法常规光镜观察71例前列腺癌患者的病理组织学形态并进行Gleason分级评分,应用免疫组织化学(SP法)检测P504s、p63、34βE12的表达。
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  patients with prostate cancer
Influence of Organ at Risk Definition on Rectal Dose-Volume Histograms in Patients with Prostate Cancer Undergoing External-Beam
      
Methods: Total RNA was isolated from patients with prostate cancer and from normal people, and poly(A) RNA was further purified.
      
The relationship of PSA, PSAD and clinicopathological stage in patients with prostate cancer
      
Some herbal agents and micronutrients have demonstrated biologic activity that may benefit patients with prostate cancer.
      
Management of asymptomatic rise in prostatic-specific antigen in patients with prostate cancer
      
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  prostate cancer patients
Identification of a high frequency of chromosomal rearrangements in the centromeric regions of prostate cancer patients
      
The aim of the present investigation was to study the major chromosomal aberrations (CA) like deletion, translocation, inversion and mosaic in prostate cancer patients of Tamilnadu, Southern India.
      
Analysis of Competing Risk Parameters in Irradiated Prostate Cancer Patients
      
Retrospective competing risk analysis of prognostic factors in definitive-irradiated prostate cancer patients.
      
Dose to Bone Marrow Using IMRT Techniques in Prostate Cancer Patients
      
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The androgen receptors in biopsy specimens of 22 cases of human prostatic cancer(PC) were studied by radioligand binding assay. The cytoplasmic androgen receptor (AcR) and nuclear androgen receptor(AnR) densities wewe 305.70±461.68 and 363.04±391.44 pmol/g protein respectively, both were significantly higher than those of 36 benigh prostatic hypertrophy (BPH) and 9 normal prostate(NP). Among the prostatic cancers, the AnR/AcR ratios were significantly different between metastatic and primary cancers. This result...

The androgen receptors in biopsy specimens of 22 cases of human prostatic cancer(PC) were studied by radioligand binding assay. The cytoplasmic androgen receptor (AcR) and nuclear androgen receptor(AnR) densities wewe 305.70±461.68 and 363.04±391.44 pmol/g protein respectively, both were significantly higher than those of 36 benigh prostatic hypertrophy (BPH) and 9 normal prostate(NP). Among the prostatic cancers, the AnR/AcR ratios were significantly different between metastatic and primary cancers. This result suggested that there might be migration of AR from nucleus to cytosoi in the process of metastasis. The serum testosterone studied by RIA method are significantly lower than that of BPH and NP. Thawmounted autoradiography demonstrated that AR were mainly located in epithelial cells of the glandular tissue of prostate.

采用放射配基结合分析法测定人前列腺癌(PC)穿刺标本的雄激素受体(AR)含量,其胞浆受体(AcR)及胞核受体(AnR)分别为305.70±461.68,363.04±391.44pmol/g蛋白,与36例前列腺增生症(BPH)及9例正常前列腺组织含量相比均有显著性差异,显示前列腺癌的雄激素依赖性。22例前列腺癌患者中未转移组的AnR/AcR比值明显大于转移组,提示前列腺癌转移过程中AnR向胞浆转移的可能性。前列腺癌患者的血清睾酮水平明显低于前列腺增生症患者及正常人。放射自显影术显示雄激素受体定位以前列腺上皮细胞核为主,表明雄激素通过与核内受体结合调控肿瘤发生发展的可能性。

Anti-HNK-1 monoclonal antibody(MAb)originally found to direct against natural killer cells, was revealde to be reactive with non-cancerous and cancerous prostatic epithelial cells.However, the clinical significane of HNK-1 antigen remains unknown. In this report,the expression of HNK-1 antigen on prostatic cancer was immunohistochemically investigated by avidin biotin peroxidase comples(ABC) method with anti-HNK-1 MAb. The relationships between the immunoreactions and tumor defferentiation and surveval rate...

Anti-HNK-1 monoclonal antibody(MAb)originally found to direct against natural killer cells, was revealde to be reactive with non-cancerous and cancerous prostatic epithelial cells.However, the clinical significane of HNK-1 antigen remains unknown. In this report,the expression of HNK-1 antigen on prostatic cancer was immunohistochemically investigated by avidin biotin peroxidase comples(ABC) method with anti-HNK-1 MAb. The relationships between the immunoreactions and tumor defferentiation and surveval rate were studied. Of the 52 cases with prostatic cancer, 49 cases (94%)were reactive with anti-HNK-1 MAb and the immunoreaction was associtated with the histological defferetiantion of prostatic cancer. Well differentiated cancer has shown the highest percentage of positive cancer has shown the gighest percentage of pasitive cancre cells and the strongest staining, while poorly differentiated cancer had the lowest percentage and the weakest staining. Further study on the five year surviveal rate and the interval without progression by Kaplan-Meier method on 33 stage D2 cases who had received endocrine therapy revealed that a higher surveval rate and a longer ingterval without progression being observed in the group with more tha twothirds of positive cancer cells. This suggests that expressino of HNK-1 antigen on prostatic cancer may serve as a useful prognostic foactor for patients with prostatic cancer.

采用抗HNK-1单克隆抗体,对52例前列腺癌组织的石蜡切片进行免疫组化(ABC法)研究。观察免疫组化染色后,阳性癌细胞的比率及染色强度,并探讨抗HNK-1免疫组化反应与患者5年生存率及非进展率的关系。结果表明:52例前列腺癌患者中,49例呈阳性染色,总阳性率为94%。阳性癌细胞比率及染色强度均与肿瘤分化度有关。高分化癌的阳性癌细胞比率最高,染色最深;低分化癌的阳性癌细胞比率最低,染色最弱。用Kaplan-Meier法对33例D_2期患者5年生存率及非进展率研究表明:阳性癌细胞比率大于2/3组,其生存率及非进展率显著高于阳性癌细胞比率低于2/3组。结果提示:抗HNK-1单克隆抗体可检测前列腺癌的存在,而且HNK-1抗原的含量与肿瘤的分化有关,分化越好,HNK-1含量越高;反之越低。HNK-1抗原的检测对判断前列腺癌患者的预后具有重要意义。

Prostate specific antigen desity (PSAD)was studied in 10 cases of non-metastatic prostate cancer and 200cases of BPH.The mean PSAD values for prostate cancer and BPH were 0. 711 and 0. 075 respectively(P<0. 001). 8 out of 9 patients with PSAD greater than 0.2 had prostate cancer, in which 3 had a PSA less than 10ng/ml and 1 below 2. 8 ng/ml. In contrast. none of the 16 patients with PSAD less than 0. 1 had prostate cancer.Furthermore,7 out of 16 BPH patients were found to have a PSA greater than 2. 8 ng/ml and...

Prostate specific antigen desity (PSAD)was studied in 10 cases of non-metastatic prostate cancer and 200cases of BPH.The mean PSAD values for prostate cancer and BPH were 0. 711 and 0. 075 respectively(P<0. 001). 8 out of 9 patients with PSAD greater than 0.2 had prostate cancer, in which 3 had a PSA less than 10ng/ml and 1 below 2. 8 ng/ml. In contrast. none of the 16 patients with PSAD less than 0. 1 had prostate cancer.Furthermore,7 out of 16 BPH patients were found to have a PSA greater than 2. 8 ng/ml and another 3 greater than 10ng/ml.these results showed that PSAD might be an effective indicator in screening early prostate cancer when the serum PSA has been moderately elevated or normal.

对10例非转移性前列腺癌和20例前列腺增生的前列腺特异性抗原密度(PSAD)进行研究。前列腺癌平均PSAD值为0.711,而前列腺增生为0.075;两者有极显著性差异(P<0.001)。9例PSAD>0.2者,8例为前列腺癌。16例PSAD<0.1者,无1例前列腺癌。8例前列腺癌患者中有3例前列腺特异性抗原(PSA)<10ng/ml,1例<2.8ng/ml。16例前列腺增生患者中7例PSA>2.8ng/ml,3例>10ng/ml。表明血清PSA轻中度增高或正常时,PSAD可作为前列腺癌早期筛选诊断的有效指标之一。

 
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