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肾病综合征出血热
相关语句
  nephrotic syndrome with hemorrhagic fever
     Clinical values of detecting thrombus-regulated protein on nephrotic syndrome with hemorrhagic fever
     肾病综合征出血热血栓调节蛋白测定的临床价值
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  “肾病综合征出血热”译为未确定词的双语例句
     Objective To observe the removal of tumor necrosis factor-α (TNF-α ), interleukin-6 (IL-6) and endothelin-1 (ET-1) in continuous renal replacement therapy (CRRT) on hemorrhagic fever with renal syndrome (HFRS) patients, and investigate the effect of inflammatory mediators on HFRS.
     目的 通过观察连续性肾替代治疗 (CRRT)对肾病综合征出血热 (HFRS)患者肿瘤坏死因子α(TNF α)、白介素 6(IL 6 )及内皮素 1(ET 1)的清除作用 ,探讨炎症介质在HFRS中的作用。
短句来源
     There were 105 cases in total, with 4 cases died. The cases were found all over the district, including 11 towns and 70 administrative villages. The cumulative incidence rate was 2.90 / 100000, the mortality rate was 0.11/10 000, and the case fatality rate was 3.81%.
     9年共发生肾病综合征出血热105例,死亡4例,累计发病率为2.90/10万,死亡率为0.11/10万,病死率3.81%;
短句来源
     ADULT MOUSE MODEL OF HEMORRHAGIC FEVER WITH RENAL SYNDROME
     肾病综合征出血热的成龄鼠模型
短句来源
     Radiolabeling of HFRSV in Infected Cells
     肾病综合征出血热病毒(HFRSV)的细胞内放射性标记
短句来源
     These observations suggest that the dynamic changes of IL-6 concentrations were in accord with the developments ofHFRS and that IL-6 might be one of the factorsleading to the pathologic lesions of HFRS.
     提示IL-6含量变化与病程进展一致,是引起肾病综合征出血热病理损伤的重要因素之一;
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  相似匹配句对
     Das nephrotische Syndrom
     肾病综合征
短句来源
     Management of Idiopathic Nephrotic Syndrome in Children
     肾病综合征的治疗
短句来源
     Radiolabeling of HFRSV in Infected Cells
     肾病综合征出血热病毒(HFRSV)的细胞内放射性标记
短句来源
     ADULT MOUSE MODEL OF HEMORRHAGIC FEVER WITH RENAL SYNDROME
     肾病综合征出血热的成龄鼠模型
短句来源
     Clinical values of detecting thrombus-regulated protein on nephrotic syndrome with hemorrhagic fever
     肾病综合征出血热血栓调节蛋白测定的临床价值
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Intracerebral infection of hemorrhagic fever with renai syndrome(HF-RS ) virus proves highly pathogenic for newborn mice, but harmless for adult mice. We observed that cyclophosphamide ( CY )-immunosuppressed adult mice were Susceptible to acute infection leading to death.4-8 week old C57 mice or outbred Kunming strain mice inoculated in-tracerebrally with HFRS virus A-16 strain and immunosuppressed with four 50mg/kg CY doses at days -1, +1, + 2, + 4 (day O:virai infection), developed a lethal disease(94% mortality...

Intracerebral infection of hemorrhagic fever with renai syndrome(HF-RS ) virus proves highly pathogenic for newborn mice, but harmless for adult mice. We observed that cyclophosphamide ( CY )-immunosuppressed adult mice were Susceptible to acute infection leading to death.4-8 week old C57 mice or outbred Kunming strain mice inoculated in-tracerebrally with HFRS virus A-16 strain and immunosuppressed with four 50mg/kg CY doses at days -1, +1, + 2, + 4 (day O:virai infection), developed a lethal disease(94% mortality ) , and were mori-bund by 14-18 days postinfection. Specific virai antigen was regularly found in brain, lung, spleen, liver and kidney by indirect IF assay. His-topathologic study showed vascular changes including hyperemia, hemorr-hage, exudate, degeneratiem and necrosis of parenchymal tissues of brain, lung, liver and kidney. Based on these findings, We suggest that C57 mice or kunming strain mice may be used as an animal modei for inves-tigation of the disease.

4~8周龄的近交系C57或杂交昆明系小鼠,脑内接种肾病综合征出血热(HFRS)病毒。在第-l、+1,+2、+4天注射环磷酰胺50mg/kg体重(第0天感染病毒),可使小鼠由隐性感染变为急性致死性感染,病死率为94%。在病死动物的脑,肺、肝、脾和肾等器官中,检查翻HFRS病毒抗原。这些器官显示微血管系统和实质组织的病变。这种成龄鼠模型可用于本病的研究。

The interleukin-6 (IL-6) concentrations in 102 serum samples sequentially collectedfrom 36 patients with hemorrhagic fever with renalsyndrome (HFRS) were determined by double antibody sandwich ELISA. It was observed that serumIL-6 concentrations in HFRS patients were elevated6 days before onset of disease and at the fever and oliguria stages of the disease in comparison with normal controls. The IL-6 concentrations in HFRSpatients reached peak value at day 6 after onset of disease and began to decrease from...

The interleukin-6 (IL-6) concentrations in 102 serum samples sequentially collectedfrom 36 patients with hemorrhagic fever with renalsyndrome (HFRS) were determined by double antibody sandwich ELISA. It was observed that serumIL-6 concentrations in HFRS patients were elevated6 days before onset of disease and at the fever and oliguria stages of the disease in comparison with normal controls. The IL-6 concentrations in HFRSpatients reached peak value at day 6 after onset of disease and began to decrease from day 7,serum IL-6 concentrations greatly increased at fever stage,peaked at oliguria stage. There were significant differences among the IL-6 concentrations in mild.middle, severe and grave type of patients with HFRS. Serum IL-6 levels were positively associatedwith urine protein in HFRS patients. These observations suggest that the dynamic changes of IL-6 concentrations were in accord with the developments ofHFRS and that IL-6 might be one of the factorsleading to the pathologic lesions of HFRS. IL-6 was closely related to the seventy of HFRS and thus it could reflect the prognosis and outcome as well as the seventy of renal impairment of HFRS patients.

用双抗体夹心ELISA法检测36例肾综合征出血热102份系列血清中IL-6含量,发现患者血清IL-6含量在6病日前及发热低血压期均高于正常;6病日达高峰,7病日开始下降;发热期明显升高,少尿期达峰值;IL-6含量在轻、中、重及危重型患者之间有明显差异;IL-6与尿蛋白在含量间明显正相关。提示IL-6含量变化与病程进展一致,是引起肾病综合征出血热病理损伤的重要因素之一;且与病情轻重密切相关,可一定程度判定患者预后和转归,反映肾损伤程度。

To assess the value of reverse transcription polymerase chain reaction (RTPCR) and indirected ELISA for disagnosising patients sera with hemorragic fever with renal syndrome(HFRS).Methods RTPCR was used to detected hantavirus(HV) RNA and specific IgM antibody was detected by indirected ELISA in sera of patients with HFRS in different phase.Results The total positive was 847%,according to the days after onset of disease the HVRNA detection rate was 100%,60%,33.3% on the days of less the 7,8~14 and more than...

To assess the value of reverse transcription polymerase chain reaction (RTPCR) and indirected ELISA for disagnosising patients sera with hemorragic fever with renal syndrome(HFRS).Methods RTPCR was used to detected hantavirus(HV) RNA and specific IgM antibody was detected by indirected ELISA in sera of patients with HFRS in different phase.Results The total positive was 847%,according to the days after onset of disease the HVRNA detection rate was 100%,60%,33.3% on the days of less the 7,8~14 and more than 15 respectively.On the other hand,HVIgM detection rate was 64%,90%,66.6% respectively,the total IgM detection rate was 70.05%.The difference was nonsignificant (P>0.05).Conclusions RTPCR and ELISA were specific,sensitive methods for diagnosing HFRS patients.They can supply other than replace each other for raising accurately diagnositic rate.

寻找一种快速、敏感、特异的诊断肾病综合征出血热 (HFRS)方法。方法 采用碘化钠 -异硫氰酸胍 -氯仿法抽提病毒核酸 ,逆转录聚合酶链反应 (RT-PCR)检测不同病程中 HFRS患者血清中的汉坦病毒感染情况 ,并采用间接酶联免疫吸附试验 (EL ISA)检测特异性 Ig M抗体。结果  84.7%患者血清中汉坦病毒核酸检测为阳性 ,其中病程为 1周内者检出率为 10 0 % ,1~ 2周者为 6 0 % ,超过 2周者为 33.3% ,而特异性 Ig M的总检出率为 70 .0 5 % ,病程在 1周、1~ 2周、超过 2周者检出率分别为 6 4%、90 %、6 6 .6 %。结论 RT-PCR和 ELISA都是 HFRS的特异性诊断方法 ,两者可相互补充 ,提高诊断率

 
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