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   急性特发性血小板减少性紫癜 的翻译结果: 查询用时:0.267秒
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急性特发性血小板减少性紫癜
相关语句
  acute idiopathic thrombocytopenic purpura
     Eexpression of Foxp3 and CD4~+CD_(25)~+ Regulation T Cells in Children with Acute Idiopathic Thrombocytopenic Purpura
     Foxp3基因表达与CD4~+CD_(25)~+调节性T细胞在急性特发性血小板减少性紫癜发病中的作用
短句来源
     Relationship between acute idiopathic thrombocytopenic purpura and human parvovirus B 19 infection
     急性特发性血小板减少性紫癜与人细小病毒B19感染的关系
短句来源
     OBJECTIVE To study the relationship between acute idiopathic thrombocytopenic purpura(ITP) in children and human parvovirus(HPV) B 19 infection.
     [目的]探讨儿童急性特发性血小板减少性紫癜(ITP)与人细小病毒B 19(HPVB 19)感染的关系.
短句来源
     Objective To investigate the amount of CD4+CD_(25)~+ regulation T cells(Tr cells) and the expression of Foxp3 in peripheral blood in children with acute idiopathic thrombocytopenic purpura(AITP),and analyze the relationship between CD4+CD_(25)~+ Tr cells and the immunopathogenesis of AITP.
     目的研究Foxp3基因与CD4+CD25+调节性T细胞(Tr细胞)在急性特发性血小板减少性紫癜(AITP)患儿中的表达变化,探讨其在AITP发病机制中的作用。
短句来源
     Objective To explore the significant changes of transcription factor GATA- 1 and nuclear factor erygthroid 2 (NF -E2) in megakaryocytes of bone marrow in children with acute idiopathic thrombocytopenic purpura( AITP).
     目的探讨转录因子GATA-1和NF-E2在急性特发性血小板减少性紫癜(AITP)患儿骨髓巨核细胞表达水平的改变及其意义。
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  “急性特发性血小板减少性紫癜”译为未确定词的双语例句
     Objective To investigate the amount of CD4+CD25+ regulation T cells and the levels of related cytokines in peripheral blood in acute ITP children,and to analyze the relationships between CD4+ CD25+ regulation T cells and the immunopathogenesis of AITP.
     目的检测急性特发性血小板减少性紫癜(AITP)患儿外周血CD4+CD25+调节性T细胞(regulationTcells,Tr细胞)及相关细胞因子的变化,探讨它们在AITP发病机制中的作用。
短句来源
     Objective To investigate the expression of Fas,FasL on T cell subsets and thrombocyte in patients with idiopathic thrombocytopenic purpura(ITP) and disuss the role of Fas,FasL in ITP pathogenesis.
     目的检测凋亡相关蛋白Fas、FasL在急性特发性血小板减少性紫癜(ITP)患儿T细胞亚群及血小板中的表达,分析其在ITP发病机制中的作用。
短句来源
     Methods TGF-β_1 and TPO levels in the serum and bone marrow of children with ITP,AA,ALL were detected using enzyme-linked immunosorbent assay(ELISA).
     方法采用ELISA法测定急性特发性血小板减少性紫癜、再生障碍性贫血、急性淋巴细胞白血病患儿血清及骨髓上清液中TGF-β1、TPO水平。
短句来源
     Objective To investigate lymphocytes apoptosis,Bcl-2 protein and Bax protein expression in children with acute idiopathic thrombocytopenic purura(AITP).
     目的探讨急性特发性血小板减少性紫癜(AITP)患儿外周血淋巴细胞凋亡情况及凋亡蛋白Bc l-2和Bax蛋白表达情况。
短句来源
     Objective To discuss the most effectiveness method to treat children ITP.
     目的探讨儿童急性特发性血小板减少性紫癜(ITP)治疗的最有效方法。
短句来源
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  相似匹配句对
     Observation of immunologic status in children with acute idiopathic thrombocytopenic purpura.
     急性特发性血小板减少性紫癜免疫功能的观察
短句来源
     Treatment of the acute children idiopathic thrombocytopenic purpura with impact therapeutics of methylprednisolone
     甲基强的松龙冲击疗法治疗儿童急性特发性血小板减少性紫癜
短句来源
     Acute Appendictics
     急性阑尾炎
短句来源
     Acute Infectious Hepatitis (4)
     急性传染性肝炎
短句来源
     Splenectomy for idiopathic thrombocytopenic purpura
     脾切除治疗特发性血小板减少性紫癜
短句来源
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  acute idiopathic thrombocytopenic purpura
A case of fatal intracranial hemorrhage is reported in an eleven year old girl with acute idiopathic thrombocytopenic purpura following a viral infection.
      
Controversies in the management of acute idiopathic thrombocytopenic purpura
      


wo hundred and forty cases of thirteen kinds ofblood diseases were treated with splenectomy. The effec-tive rates of 130 cases of ITP were 83. 1%.The opera-tive effects in 25 CAA 11 AIHA and 11 cases withHBE-β thalassemia were 65. 2%, 66. 6%, 90. 9% re-spectively. The Hb level in 29 cases of HbH diseasse and18 cases of HS were increased with an average value of35g/L and 58. 6g/L after splenectomy.The liner tropic equation (Y= 8. 432- 0.874X) thatwe established might be used to predict the effects ofsplenectomy...

wo hundred and forty cases of thirteen kinds ofblood diseases were treated with splenectomy. The effec-tive rates of 130 cases of ITP were 83. 1%.The opera-tive effects in 25 CAA 11 AIHA and 11 cases withHBE-β thalassemia were 65. 2%, 66. 6%, 90. 9% re-spectively. The Hb level in 29 cases of HbH diseasse and18 cases of HS were increased with an average value of35g/L and 58. 6g/L after splenectomy.The liner tropic equation (Y= 8. 432- 0.874X) thatwe established might be used to predict the effects ofsplenectomy in patients with HbH discase.Gallstones were detected in 8 out of 75 hemolytic ane-mia. Splenectomy and cholecystectomy were carried outsimultaneously in 7 cases. To perform both procedures amedian upper abdominal incision was proved to be thebest approach. The distribution of T, B lymphocytes and T cell sub-populations in the spleens of ITP patients were studiescomparatively with that of incident rupture. The mor-phology and ultrastructure of spleens of some blood dis-eases were studied too. These experimental results of-fered new description for etiology of some blood diseasesand the mechanisrn of their curative effect.

对240例血液病脾切除术的疗效与合并症进行了分析;同时提出急性特发性血小板减少性紫癜(急性ITP)合并严重出血并危及生命时,应行紧急脾切除术;本组中75例溶血性贫血(HA)合并胆结石8例,其中7例采用上腹正中切口行脾脏和胆囊同期手术;另外对切除的脾脏进行了观察研究。

Using PCR and ELISA skills,human parvovirus B19(HPV B19),Epstein Barr virus(EBV),cytomegalovirus(CMV)and hepatitis B virus(HBV) were detected in 32 children with acute idiopathic thrombocytopenic purpura(ITP).The results showed that positive HPV B19 DNA was observed on 8 cases(25.0%)in the ITP group and 1 in the control group( P <0.05).Positive EBV DNA,CMV DNA and HBV antigens were detected on 2,3 and 2 cases,respectively.The total positive rate of these 4 viruses was 46 9%(15/32). It is suggested that...

Using PCR and ELISA skills,human parvovirus B19(HPV B19),Epstein Barr virus(EBV),cytomegalovirus(CMV)and hepatitis B virus(HBV) were detected in 32 children with acute idiopathic thrombocytopenic purpura(ITP).The results showed that positive HPV B19 DNA was observed on 8 cases(25.0%)in the ITP group and 1 in the control group( P <0.05).Positive EBV DNA,CMV DNA and HBV antigens were detected on 2,3 and 2 cases,respectively.The total positive rate of these 4 viruses was 46 9%(15/32). It is suggested that the pathegenesis of nearly 1/2 childhood ITP cases probably correlates with virus infections,specially HPV B19 infection.

应用 P C R 和 E L I S A 技术对32 例急性特发性血小板减少性紫癜( I T P) 患儿的外周血进行了人细小病毒 B19( H P V B19) 、 E B 病毒( E B V) 、巨细胞病毒( C M V) 及乙型肝炎病毒( H B V) 系列检测。结果:病例组 H P V B19 D N A 阳性8 例(25 .0 % ) ,与正常对照组比较有显著性差异( P< 0 .05) 。 E B V D N A 阳性2 例, C M V D N A 阳性3 例, H Bs Ag 和 H Be Ag 同时阳性2 例,4种病毒的总阳性率为46 .9 % (15/32 例) 。提示:近半数儿童 I T P 病例的发生可能与上述病毒感染有关,而 H P V B19 较其他病毒与 I T P 的关系更为密切。

Objective To explore the significance of serum thrombopoietin (TPO) and its receptor (c MPL) mRNA changes in platelets in children with acute idiopathic thrombocytopenic purpura (AITP). Methods The serum TPO and platelet associated IgG (PAIgG) were detected by ELISA. The mRNA levels of c MPL in platelets were determined by semi quantitative reverse transcription polymerase chain reaction (RT PCR). Results Before treatments in chidren with ITP the serum TPO levels were mildly elevated and c MPL mRNA...

Objective To explore the significance of serum thrombopoietin (TPO) and its receptor (c MPL) mRNA changes in platelets in children with acute idiopathic thrombocytopenic purpura (AITP). Methods The serum TPO and platelet associated IgG (PAIgG) were detected by ELISA. The mRNA levels of c MPL in platelets were determined by semi quantitative reverse transcription polymerase chain reaction (RT PCR). Results Before treatments in chidren with ITP the serum TPO levels were mildly elevated and c MPL mRNA levels in platelets were decreased, when compared with normal controls. After the treatment with high does methylprednisolone, the serum TPO levels decrease gradually along with the elevation of platelets. The c MPL mRNA levels in platelets increased with the decrease of PAIgG levels. Conclusion The platelet quantity might regulate the serum TPO level. The down regulated transcription of c MPL mRNA might cause maturity disturbance of megakaryocytes and decrease production of platelets, which may be one of the important factors in the pathogenesis of AITP.

目的 探讨急性特发性血小板减少性紫癜 (AITP)患儿血小板生成素 (TPO)及血小板TPO受体c MPLmRNA基因转录水平变化的意义。方法 采用ELISA法检测血清TPO、血小板相关抗体 (PAIgG)水平 ;半定量RT PCR法检测外周血血小板c MPLmRNA的相对量。结果 AITP患儿初治时血浆TPO水平增高 ,血小板c MPLmRNA较低 ;经大剂量甲基强的松龙冲击治疗后 ,伴随血小板计数增高 ,血清TPO水平逐渐下降 ,血小板c MPLmRNA增高 ,且与PAIgG呈负相关。结论 血小板数可调控血清TPO水平 ;AITP患儿初诊时c MPLmRNA基因转录下调 ,可能导致骨髓巨核细胞成熟障碍 ,血小板生成减少 ,是AITP发病的重要因素之一。

 
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