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前列腺移行带特异性抗原密度
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  prostate specific antigen transition zone density
     Objective To determine the predictive value of serum prostate specific antigen (PSA),prostate specific antigen density (PSA D) and prostate specific antigen transition zone density(PSAT) in prostate biops y.
     目的探讨血清前列腺特异性抗原(PSA)、前列腺特异性抗原密度(PSAD)和前列腺移行带特异性抗原密度(PSAT)在前列腺穿刺活检中的意义。
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  “前列腺移行带特异性抗原密度”译为未确定词的双语例句
     Objective To study and to compare the prostate specific antigen density of the transitional zone(PSAT),the prostate specific antigen (PSA) and prostate specific antigen densigy (PSAD) in the diagnosis of prostate carcinoma.
     目的 比较前列腺移行带特异性抗原密度 (PSAT)与前列腺特异性抗原 (PSA)及前列腺特异性抗原密度 (PSAD)在前列腺癌诊断中的意义。
短句来源
     Objective:To evaluate the diagnostic efficacy of the prostate specific antigen density of the transitional zone(PSAT) and the prostatic biopsy for prostatic cancer.
     目的 :评价前列腺移行带特异性抗原密度 (PSAT)与前列腺穿刺活检联合检测在前列腺癌 (PCa)诊断中的价值。
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  相似匹配句对
     Prostate specific antigen density of transition zone in detecting prostate cancer
     前列腺移行特异抗原密度检测前列腺癌的临床观察
短句来源
     Diagnostic Value of Prostate Specific Antigen Density of Transition Zone in Prostate Cancer
     超声测量移行前列腺特异性抗原密度前列腺癌的诊断价值
短句来源
     Research on the specific antigen associated with prostate.
     前列腺特异性抗原的相关性研究
短句来源
     Quantitative analysis of histological components in prostatic transition zone
     前列腺移行组织学定量分析
短句来源
     Prostate Specific Antigen Density in Screening of Prostate Cancer
     前列腺特异性抗原密度前列腺癌筛选中的应用
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Objective To study and to compare the prostate specific antigen density of the transitional zone(PSAT),the prostate specific antigen (PSA) and prostate specific antigen densigy (PSAD) in the diagnosis of prostate carcinoma. Methods From Aug. 1998 to Nov.1999,78 cases with a serum PSA 4~20 ng/ml underwent biopsy of the prostate.After the histopathological diagnosis has been established,the value of PSA,PSAD and PSAT were evaluated. Results Of the 78 cases,32 were prostate cancer (Pca) and 46 benign prostatic...

Objective To study and to compare the prostate specific antigen density of the transitional zone(PSAT),the prostate specific antigen (PSA) and prostate specific antigen densigy (PSAD) in the diagnosis of prostate carcinoma. Methods From Aug. 1998 to Nov.1999,78 cases with a serum PSA 4~20 ng/ml underwent biopsy of the prostate.After the histopathological diagnosis has been established,the value of PSA,PSAD and PSAT were evaluated. Results Of the 78 cases,32 were prostate cancer (Pca) and 46 benign prostatic hyperplasia (BPH).The mean value of PSA in Pca and BPH patients were (14.32±1.46) ng/ml and (13.89±1.52) ng/ml,the difference being statistically insignificant.The mean value of PSAD were 0.43±0.14 and 0.36±0.17,the difference was statistically significant ( P < 0.05 ).The mean value of PSAT were 0.75±0.19 and 0.31±0.06,the difference of PSAT was statistically very significant ( P <0.01).Conclusions PSAD and PSAT are valuable and helpful in the screening diagnosis of prostate cancer in patients with PSA less than 20 ng/ml.PSAT seems to be more reliable.

目的 比较前列腺移行带特异性抗原密度 (PSAT)与前列腺特异性抗原 (PSA)及前列腺特异性抗原密度 (PSAD)在前列腺癌诊断中的意义。 方法 对 78例PSA 4~ 2 0ng/ml的患者行前列腺穿刺活检后比较PSA、PSAD和PSAT指标。 结果  78例中 ,病理诊断为前列腺癌 (PCa) 32例 ,良性前列腺增生 (BPH) 4 6例 ,二者PSA平均值分别为 (14.32± 1.46 )ng/ml、(13 .89± 1.5 2 )ng/ml,二者相比差别无显著性意义 (P >0 .0 5 ) ;PSAD平均值分别为 0 .43± 0 .14、0 .36± 0 .17,二者相比差别有显著性意义 (P <0 .0 5 ) ;PSAT平均值分别为 0 .75± 0 .19、0 .31± 0 .0 6 ,二者相比差别有非常显著性意义 (P <0 .0 1)。 结论 PSAD和PSAT对预测PSA <2 0ng/ml的患者是否患前列腺癌有较大帮助 ,特别是PSAT更为准确。

Objective:To evaluate the diagnostic efficacy of the prostate specific antigen density of the transitional zone(PSAT) and the prostatic biopsy for prostatic cancer.Method:The diagnostic value of PSAT for 73 cases with a serum PSA>10 ng/ml underwent prostate biopsy were evaluated.Result:In the 73 cases, 48 were prostate cancer(PCa) and 25 benign prostatic hyperplasia(BPH). The mean value of PSAT were 0.67± 0.15 and 0.38± 0.14, respectively, the difference of PSAT had magnificant statistical significance...

Objective:To evaluate the diagnostic efficacy of the prostate specific antigen density of the transitional zone(PSAT) and the prostatic biopsy for prostatic cancer.Method:The diagnostic value of PSAT for 73 cases with a serum PSA>10 ng/ml underwent prostate biopsy were evaluated.Result:In the 73 cases, 48 were prostate cancer(PCa) and 25 benign prostatic hyperplasia(BPH). The mean value of PSAT were 0.67± 0.15 and 0.38± 0.14, respectively, the difference of PSAT had magnificant statistical significance (P< 0.01). The histopathology after operations indicated that there were 6 Pca in 25 BPH cases, The mean value of PSAT were 0.40± 0.12 (6 Pca) and 0.31± 0.07 (19 BPH), the difference between them was statistically significant (P< 0.05).Conclusion:PSAT is more sensitive than the prostatic biopsy for the diagnosis of PCa, especially for the screening diagnosis. The combination of the PSAT and the prostatic biopsy is valuable for the clinical diagnosis and treatment of Pca.

目的 :评价前列腺移行带特异性抗原密度 (PSAT)与前列腺穿刺活检联合检测在前列腺癌 (PCa)诊断中的价值。方法 :对 4 9例血清PSA >10 μg/L患者行前列腺穿刺活检后 ,部分给予重复穿刺及手术治疗 ,综合比较PSAT。结果 :4 9例中 ,前列腺活检病理检查诊断为PCa 2 4例 (4 8.98% ) ,良性前列腺增生 (BPH) 2 5例 (5 1.0 2 % ) ,其PSAT平均值分别为 (0 .6 1± 0 .11)、(0 .38± 0 .13) μg/L ,两者相比差别有统计学意义 (P <0 .0 1) ;后者行手术治疗后病理检查诊断为PCa 6例 (2 4 % ) ,BPH 19例 (76 % ) ,其PSAT平均值分别为 (0 .4 0± 0 .11)、(0 .32± 0 .0 7) μg/L ,两者相比差别有统计学意义 (P <0 .0 5 )。结论 :PSAT对PCa ,特别是早中期PCa的诊断 ,比前列腺穿刺活检更为敏感 ,二者联合检测对临床诊治有重要的价值和意义。

Objective To determine the predictive value of serum prostate specific antigen (PSA),prostate specific antigen density (PSA D) and prostate specific antigen transition zone density(PSAT) in prostate biops y. Methods Prostate biopsy was performed in 192 subjects ; among them, 184 subjects had PSA≥4 ng/ml,and 8 subjects had PSA<4 ng/ml and positive findings for digital rectal examination and transrectal ultrasound, whi ch were suspicious of cancer.The associations of PSA, PSAD and PSAT with the pro state biopsy...

Objective To determine the predictive value of serum prostate specific antigen (PSA),prostate specific antigen density (PSA D) and prostate specific antigen transition zone density(PSAT) in prostate biops y. Methods Prostate biopsy was performed in 192 subjects ; among them, 184 subjects had PSA≥4 ng/ml,and 8 subjects had PSA<4 ng/ml and positive findings for digital rectal examination and transrectal ultrasound, whi ch were suspicious of cancer.The associations of PSA, PSAD and PSAT with the pro state biopsy results were analyzed. Results Prostate can cer on prostate biopsy was detected in 100 of the 192 subjects (52.1%). Among th e 8 subjects with PSA<4ng/ml, one had prostate rhabdomyosarcoma and 7 had BPH.A mong the 93 subjects with serum PSA>20 ng/ml,80(86.0%) had prostate cancer.Amon g the 91 subjects with serum PSA from 4 to 20 ng/ml,19 (20.9%) had prostate canc er.The results indicated that for subjects with serum PSA 4-20 ng/ml and PSAD>0 .10 or PSAT>0.10,the sensitivity was 100%, the specificity was 11.1% or 4.2%, a nd the positive predictive value was 22.9% or 21.6%, such that negative prostate biopsy of 8.8% or 3.3% was avoided.Within the range of serum PSA of 4-20 ng/ml, in positive biopsy group and negative biopsy group,PSA values were (13.2±4.7) a nd (11.4±4.6)ng/ml,respectively (P>0.05);PSAD values were 0.36±0.18 and 0. 19±0.09,respectively ( P= 0.001 );PSAT values were 0.67±0.36 and 0.32 ±0.18, respectively (P=0.000).The area under ROC curve for PSA, PSAD and PS AT were 0.613,0.810 and 0.833, respectively,which indicated that PSAD and PSAT w ere significantly better predictors than PSA(P<0.05). Conclusion s When PSA level is more than 20 ng/ml,prostate biopsy should be per formed.When PSA level ranges 4-20 ng/ml,PSAD and PSAT have a greater value for p redicting whether prostate biopsy should be performed.

目的探讨血清前列腺特异性抗原(PSA)、前列腺特异性抗原密度(PSAD)和前列腺移行带特异性抗原密度(PSAT)在前列腺穿刺活检中的意义。方法对192例患者行前列腺穿刺活检,其中PSA≥4ng/ml者184例,PSA<4ng/ml且直肠指诊及经直肠B超有阳性发现者8例。对PSA、PSAD和PSAT与前列腺穿刺活检的关系进行分析。结果192例患者中经前列腺穿刺诊断为前列腺癌(PCa)100例,活检阳性率52.1%,其中8例PSA<4ng/ml者中,活检结果为前列腺横纹肌肉瘤1例,良性前列腺增生7例;93例PSA>20ng/ml者中80例为PCa,活检阳性率86.0%;91例PSA4~20ng/ml者中19例为PCa,活检阳性率20.9%。血清PSA4~20ng/ml患者,PSAD>0.10或PSAT>0.10时,敏感性均为100%,特异性为11.1%或4.2%,阳性预测值为22.9%或21.6%,可避免8.8%(8/91)或3.3%(3/91)阴性穿刺结果。血清PSA4~20ng/ml时,前列腺穿刺阳性组和阴性组PSA分别为(13.2±4.7)和(11.4±4.6)ng/ml(P>0.05);PSA...

目的探讨血清前列腺特异性抗原(PSA)、前列腺特异性抗原密度(PSAD)和前列腺移行带特异性抗原密度(PSAT)在前列腺穿刺活检中的意义。方法对192例患者行前列腺穿刺活检,其中PSA≥4ng/ml者184例,PSA<4ng/ml且直肠指诊及经直肠B超有阳性发现者8例。对PSA、PSAD和PSAT与前列腺穿刺活检的关系进行分析。结果192例患者中经前列腺穿刺诊断为前列腺癌(PCa)100例,活检阳性率52.1%,其中8例PSA<4ng/ml者中,活检结果为前列腺横纹肌肉瘤1例,良性前列腺增生7例;93例PSA>20ng/ml者中80例为PCa,活检阳性率86.0%;91例PSA4~20ng/ml者中19例为PCa,活检阳性率20.9%。血清PSA4~20ng/ml患者,PSAD>0.10或PSAT>0.10时,敏感性均为100%,特异性为11.1%或4.2%,阳性预测值为22.9%或21.6%,可避免8.8%(8/91)或3.3%(3/91)阴性穿刺结果。血清PSA4~20ng/ml时,前列腺穿刺阳性组和阴性组PSA分别为(13.2±4.7)和(11.4±4.6)ng/ml(P>0.05);PSAD分别为0.36±0.18和0.19±0.09(P=0.001);PSAT分别为0.67±0.36和0.32±0.18(P=0.000)。血清PSA、PSAD和PSAT的ROC曲线下面积分别为0.613、0.810和0.833,PSAD和PSAT的ROC曲线下面积与PSA比较,差异均有统计学意义(P<0.05)。结论PSA>20ng/ml时应做前列腺穿刺活检;PSA4~20ng/ml时,PSAD和PSAT对预测患者是否行前列腺穿刺活检有较大帮助。

 
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